Abstract:
:Understanding of vascular substrates of cognitive decline in the elderly is evolving to include a major emphasis on the impact of small vessel disease (SVD). While existing concepts of multi-infarct dementia and strategic infarct dementia remain valid, they present difficulty in generalizing clinicopathological correlations from patient to patient. The range and significance of lesions that should be included as manifestations of SVD are unresolved, as is their impact on, and association with, neurodegenerative changes. This mini-review summarizes the authors' views on SVD substrates leading to cognitive decline and proposes priorities for pathological investigations of human cerebrovascular mechanisms leading to cognitive decline.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Ince PG,Fernando MSdoi
10.1017/S1041610203008998keywords:
subject
Has Abstractpub_date
2003-01-01 00:00:00pages
71-5eissn
1041-6102issn
1741-203Xpii
S1041610203008998journal_volume
15 Suppl 1pub_type
杂志文章abstract::Older widowers have high rates of completed suicide but have rarely been the subject of systematic inquiry. We investigated the prevalence of depressive symptoms and major depressive episodes (MDEs) in recently widowed older men over the first 13 months after bereavement. We employed a matched-pair longitudinal design...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610299005591
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:Delirium is frequently observed in clinical practice, particularly in medical and surgical wards and more so among patients at risk, especially elderly with preexisting central nervous system impairments. OBJECTIVE:Despite the severe consequences of delirium, epidemiological data relating to incidence of de...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610202008499
更新日期:2002-09-01 00:00:00
abstract::ABSTRACTBackground:Evidence suggests that semantic interference may be a sensitive indicator of early dementia. We examined the utility of the Semantic Interference Test (SIT), a cognitive stress memory paradigm which taps proactive and retroactive semantic interference, for predicting progression from mild cognitive ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217002666
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:Issues concerning the association among attachment anxiety, depression and suicidal ideation among the elderly have rarely been explored. The present study investigated the relationship among attachment anxiety, depression and perceived support concerning suicidal ideation among older people. DESIGN:Cross-s...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161022000054X
更新日期:2020-05-07 00:00:00
abstract:BACKGROUND:Whilst previous surveys of mental health literacy of general practitioners (GPs) have shown high rates of recognition of common mental disorders, few studies have been carried out into GPs' understanding of presentations in late life. This study aims to determine GPs' recognition of mental disorders in older...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610208008235
更新日期:2009-04-01 00:00:00
abstract::Exposure to general anesthesia has been suggested as a possible cause of long-term cognitive impairment in elderly subjects. The present study reviews the literature in this field in order to describe postoperative cognitive impairment in elderly populations, to determine to what extent this may be attributed to anest...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/s1041610297004468
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:Effectiveness of educational interventions targeted at improving delirium care is limited by implementation barriers. Studying factors which shape learning needs can overcome these knowledge transfer barriers. This in-depth qualitative study explores learning needs of hospital staff relating to care needs of...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212002074
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:The IPA Taskforce on Mental Health Issues in Long-Term Care Homes seeks to improve mental health care in long-term care (LTC) homes. The aim of this paper is to provide recommendations on comprehensive assessment of depression and behavioral problems in order to further stimulate countries and professionals ...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610210000736
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:The elderly are at high risk of developing tuberculosis. The prevalence and incidence of depression and anxiety are higher in those with tuberculosis than in the general population. A positive correlation between national suicide rates and rates of mortality due to tuberculosis has been reported. METHODS:Th...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209990378
更新日期:2009-12-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610200006505
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:The purpose of the study was to examine the attention deficit hyperactivity disorder (ADHD) symptomatology across the lifespan by comparing older individuals' self-reports about current ADHD symptoms and symptoms in childhood. METHODS:The 25-item Wender Utah Rating Scale (WURS) was initially administered in...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212002050
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:This study aimed to assess the prevalence, incidence, and persistence of suicidal ideation (SI), and to investigate the psychosocial factors associated with these. METHODS:A total of 1,204 community dwelling elderly adults aged 65 years or older were evaluated at baseline, 909 (75%) of whom were followed tw...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213001634
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to investigate the psychometric characteristics of the Perceived Stress Scale (PSS) in a sample of dementia patients and their spousal caregivers. METHODS:We investigated the reliability and validity of the 14-item PSS in a sample of 80 couples, each including one spouse who...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217001387
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Hospital-treated deliberate self harm and suicide among older adults have rarely been examined at a national level. METHODS:The Irish Central Statistics Office provided suicide and undetermined death data for 1980-2006. The National Registry of Deliberate Self Harm collected data relating to deliberate self...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210001377
更新日期:2010-12-01 00:00:00
abstract::Nimodipine is a calcium antagonist which improves learning and memory in brain-lesioned or aged animals (LeVere & Sandin, 1989; Schuurman & Traber, 1989). It also accelerates the recovery of experimentally damaged sciatic nerves (van der Zee et al., 1987) and reduces age-associated gait abnormalities in aging rats (Sc...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::ABSTRACTBackground and Purpose:The impact of dementia-related stressors and strains have been examined for their potential to threaten the well-being of either the person with dementia or the family care partner, but rarely have studies considered the dyadic nature of well-being in dementia. The purpose of this study ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021800203X
更新日期:2019-05-01 00:00:00
abstract::Cross-sectional data from Phase 1 of the Canadian Study of Health and Aging was used to examine the relationship between two self-report health measures: "How would you say your health is these days?"(HEALTH) and "How much do your health troubles stand in the way of your doing the things you want to do?"(TROUBLE). The...
journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/s1041610202008165
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:A past history of self-harm is a significant risk factor for suicide in older people. The aims of this study are to (i) characterize older people who present with self-harm to emergency departments (EDs); and (ii) determine the predictors for repeat self-harm and suicide. METHODS:Demographic and clinical da...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217000308
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:The study of predeath grief is hampered by measures that are often lengthy and not clearly differentiated from other caregiving outcomes, most notably burden. We aimed to validate a new 11-item Caregiver Grief Questionnaire (CGQ) assessing two dimensions of predeath grief, namely relational deprivation and em...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610219000309
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Depression in late life is a risk factor for cognitive decline. Depression is also associated with increased disability and social support deficits; these may precede conversion to dementia and inform risk. In this study, we examined if baseline or one-year change in disability and social support predicted l...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610214002543
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Olfactory dysfunction, impaired smell identification in particular, is known as a diagnostic and a marker of conversion in Alzheimer's disease (AD). We aimed to evaluate the associations of olfactory identification impairments with cognition, illness severity, and progression in AD patients. METHODS:Fifty-s...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213000446
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Increasing out-of-pocket health expenditure among older people worsens the inequitable access to essential health services in low and middle-income countries (LMIC). We investigated various socioeconomic and health factors associated with out-of-pocket and catastrophic health expenditures among rural older p...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021200083X
更新日期:2012-10-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 信件
doi:10.1017/S1041610217002046
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:There is a paucity of simulation-based dementia education programmes for acute care settings that support the development of interpersonal skills pertinent to good care. Moreover, few studies measure the effectiveness of such programmes by evaluating the persistence of practice change beyond the immediate ti...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218002193
更新日期:2020-12-01 00:00:00
abstract::This paper provides a review of research issues and findings on the epidemiology of delirium. Despite the fact that research on this important geriatric syndrome has been conducted for many decades, several methodological issues make it difficult to compare findings across studies. In this paper we first discuss broad...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/s1041610291000625
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Quality of Life-Alzheimer's Disease (QOL-AD) is a widely used scale for the study of quality of life in patients with dementia. The aim of this study is the transcultural adaptation and validation of the QOL-AD scale in Portugal. METHODS:Translation and transcultural adaptation was performed according to st...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213000379
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:The Cambridge Cognitive Examination (CAMCOG) is a useful test in screening for Alzheimer's disease (AD). However, the interpretation of CAMCOG cut-off scores is problematic and reference values are needed for different educational strata. Given the importance of earlier diagnoses of mild dementia, new cut-of...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021000116X
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:A careful characterization of behavioral abnormalities in corticobasal degeneration syndrome (CBDS) and progressive supranuclear palsy (PSP) by reliable tools is still lacking. Literature data provided evidence of the usefulness of the Frontal Behavioral Inventory (FBI) to operationalize such disturbances, p...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209008862
更新日期:2009-06-01 00:00:00
abstract::This paper presents updated analyses on the genetic associations of sleep disruption in individuals with Alzheimer's disease (AD). We published previously a study of the association between single nucleotide polymorphisms (SNPs) found in eight genes related to circadian rhythms and objective measures of sleep-wake dis...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610219001777
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:One in three adults, most of whom are living in a care home at the time, dies with dementia. Their end-of-life is often in hospital, where they may experience uncomfortable interventions without known benefit and die rapidly with uncontrolled pain and comfort needs. This study aimed to improve end-of-life ca...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213001221
更新日期:2013-11-01 00:00:00