Abstract:
:ABSTRACTBackground:Little is known about the combined use of benzodiazepines and antidepressants in older psychiatric patients. This study examined the prescription pattern of concurrent benzodiazepines in older adults treated with antidepressants in Asia, and explored its demographic and clinical correlates. METHODS:The data of 955 older adults with any type of psychiatric disorders were extracted from the database of the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) project. Demographic and clinical characteristics were recorded using a standardized protocol and data collection procedure. Both univariate and multiple logistic regression analyses were performed. RESULTS:The proportion of benzodiazepine and antidepressant combination in this cohort was 44.3%. Multiple logistic regression analysis revealed that higher doses of antidepressants, younger age (<65 years), inpatients, public hospital, major comorbid medical conditions, antidepressant types, and country/territory were significantly associated with more frequent co-prescription of benzodiazepines and antidepressants. CONCLUSIONS:Nearly, half of the older adults treated with antidepressants in Asia are prescribed concurrent benzodiazepines. Given the potentially adverse effects of benzodiazepines, the rationale of benzodiazepines and antidepressants co-prescription needs to be revisited.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Zhong XM,Wang F,Zhang Q,Ungvari GS,Ng CH,Chiu HFK,Si TM,Sim K,Avasthi A,Grover S,Chong MY,Chee KY,Kanba S,Lee MS,Yang SY,Udomratn P,Kallivayalil RA,Tanra AJ,Maramis MM,Shen WW,Sartorius N,Mahendran R,Tan CH,doi
10.1017/S1041610217002563subject
Has Abstractpub_date
2019-05-01 00:00:00pages
685-691issue
5eissn
1041-6102issn
1741-203Xpii
S1041610217002563journal_volume
31pub_type
杂志文章,多中心研究abstract:BACKGROUND:Religious and spiritual issues are clearly important to the older adult population and may play a positive role in maintaining health and recovering from illness. This study systematically reviewed the literature examining the effects of religion and spirituality on health outcomes such as cognitive function...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610214001665
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abstract::ABSTRACTBackground:Dementia screening is a public health priority in Taiwan, where the prevalence of dementia is increasing because of an aging population. However, the reasons affect community-dwelling people to accept a referral to memory specialist clinic after dementia screening was still unclear. To investigate t...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217002733
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journal_title:International psychogeriatrics
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doi:10.1017/S1041610212000609
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journal_title:International psychogeriatrics
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doi:10.1017/S104161021400057X
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journal_title:International psychogeriatrics
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journal_title:International psychogeriatrics
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doi:10.1017/S1041610209990639
更新日期:2009-12-01 00:00:00
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journal_title:International psychogeriatrics
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doi:10.1017/s1041610201007542
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abstract:BACKGROUND:Acute exposure to sedative drugs may induce memory impairment, but there is mixed evidence that long-term sedative use may result in incident cognitive decline. The objective of this study was to investigate the use of sedative drugs and incident cognitive decline in a population-based sample of persons aged...
journal_title:International psychogeriatrics
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journal_title:International psychogeriatrics
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journal_title:International psychogeriatrics
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journal_title:International psychogeriatrics
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pub_type: 杂志文章,评审
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journal_title:International psychogeriatrics
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更新日期:2016-05-01 00:00:00
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更新日期:1999-03-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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