Abstract:
:ABSTRACT Background: The association between disability and depression is complex, with disability well established as a correlate and consequence of late life depression. Studies in community samples report that greater volumes of cerebral white matter hyperintensities (WMHs) seen on brain imaging are linked with functional impairment. These vascular changes are also associated with late life depression, but it is not known if depression is a modifier in the relationship between cerebrovascular changes and functional impairment. Methods: The study sample was 237 older adults diagnosed with major depression and 140 never depressed comparison adults, with both groups assessed at study enrollment. The dependent variable was the number of limitations in basic activities of daily living (ADL), instrumental ADLs, and mobility tasks. The independent variable was the total volume of cerebral white matter lesions or hyperintensities assessed though magnetic resonance imaging. Results: In analyses controlling for age, sex, race, high blood pressure, and cognitive status, a greater volume of WMH was positively associated with the total number of functional limitations as well as the number of mobility limitations among those older adults with late life depression but not among those never depressed, suggesting the association between WMH volume and functional status differs in the presence of late life depression. Conclusions: These findings suggest older patients with both depression and vascular risk factors may be at an increased risk for functional decline, and may benefit from management of both cerebrovascular risk factors and depression.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Hybels CF,Pieper CF,Landerman LR,Payne ME,Steffens DCdoi
10.1017/S1041610214000829subject
Has Abstractpub_date
2014-05-09 00:00:00pages
1-9eissn
1041-6102issn
1741-203Xpii
S1041610214000829pub_type
杂志文章abstract:BACKGROUND:The aim of the present study was to investigate the psychometric characteristics of the Perceived Stress Scale (PSS) in a sample of dementia patients and their spousal caregivers. METHODS:We investigated the reliability and validity of the 14-item PSS in a sample of 80 couples, each including one spouse who...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217001387
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:This article analyzes the natural history of wandering behavior throughout the course of dementia. DESIGN:Prospective, 10-year, longitudinal study of wandering behavior in dementia, with autopsy follow-up. SETTING:Participants with dementia, living at home with a carer. All lived in Oxfordshire, UK. PARTIC...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610201007542
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:The clinical presentations in dementia with Lewy bodies (DLB) and frontotemporal dementia (FTD) overlap considerably with that of Alzheimer's disease (AD) despite different pathological processes. Autopsy studies have also shown that multiple brain pathology occurs frequently, even in cases with a single cli...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209009454
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Verbal fluency (VF) tasks are simple and efficient clinical tools to detect executive dysfunction and lexico-semantic impairment. VF tasks are widely used in patients with suspected dementia, but their accuracy for detection of mild cognitive impairment (MCI) is still under investigation. Schooling in partic...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209990639
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:The use of benzodiazepines is associated with increased risk of fall-related injuries in the elderly. However, it is unclear if the risks vary across the products and how they depend on the pattern of use and dosage. Specifically, the possibility of cumulative effects of past benzodiazepine use has not been ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211002031
更新日期:2012-04-01 00:00:00
abstract::ABSTRACTAssociations between high body mass index (BMI) and subsequent cognitive decline, reported in elderly averaging below age 75, become less consistent at older ages. We compared the associations of BMI with cognition in moderately old (ages 75-84, N = 154) and oldest-old (85+, N = 93) samples. BMI and cognition ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218001412
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Depressive symptoms are common in patients with Alzheimer's disease (AD) and increase the caregiver burden, although the etiology and pathologic mechanism of depressive symptoms in AD patients remain unclear. In this study, we tried to clarify the cerebral blood flow (CBF) correlates of subjective depressive...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213002573
更新日期:2014-05-01 00:00:00
abstract::The World Alzheimer Report 2016 estimated that 47 million people are living with dementia worldwide (Alzheimer's Disease International, 2016). In the inaugural World Health Organization Ministerial Conference on Global Action against Dementia, six of the top ten research priorities were focused on prevention, identifi...
journal_title:International psychogeriatrics
pub_type: 评论,杂志文章
doi:10.1017/S1041610218000042
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:The Cambridge Cognitive Examination (CAMCOG) is a useful test in screening for Alzheimer's disease (AD). However, the interpretation of CAMCOG cut-off scores is problematic and reference values are needed for different educational strata. Given the importance of earlier diagnoses of mild dementia, new cut-of...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021000116X
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:A past history of self-harm is a significant risk factor for suicide in older people. The aims of this study are to (i) characterize older people who present with self-harm to emergency departments (EDs); and (ii) determine the predictors for repeat self-harm and suicide. METHODS:Demographic and clinical da...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217000308
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND AND AIM:Previous research suggested caregiver singing could influence persons with severe dementia to communicate with increased competence, to cease aggression, and to cease disruptive screaming, while at the same time they seemed to understand what was going on when being cared for during morning care sess...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:Whereas the State-Trait Anxiety Inventory (STAI-Y) is probably the most widely used self-reported measure of anxiety, the lack of current norms among elderly people appears to be problematic in both a clinical and research context. The objective of the present study was to provide normative data for the STAI...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212000300
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:There is a paucity of simulation-based dementia education programmes for acute care settings that support the development of interpersonal skills pertinent to good care. Moreover, few studies measure the effectiveness of such programmes by evaluating the persistence of practice change beyond the immediate ti...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218002193
更新日期:2020-12-01 00:00:00
abstract::ABSTRACTBackground:Dementia is a neurodegenerative syndrome that interferes with multiple aspects of life, including cognition, daily functioning, and behavior. Despite the large heterogeneity in symptom development, these three domains are seldom studied simultaneously. This study investigates how trajectories of the...
journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/S1041610217000321
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Workforce shortages to meet the mental health needs of the world's aging population are well documented. Within the field of professional geropsychology in the U.S.A., a national conference was convened in 2006 to delineate competencies for psychological practice with older adults and a training model for th...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209991736
更新日期:2010-09-01 00:00:00
abstract::There is no doubt that family carers who look after a family member with dementia or with a functional mental illness fulfill an important role, not only for their loved one, but also for the health and aged care systems of the countries they live in. Due to increasing life expectancy, but also improved healthcare the...
journal_title:International psychogeriatrics
pub_type: 社论
doi:10.1017/S1041610217002150
更新日期:2017-12-01 00:00:00
abstract::Cross-sectional data from Phase 1 of the Canadian Study of Health and Aging was used to examine the relationship between two self-report health measures: "How would you say your health is these days?"(HEALTH) and "How much do your health troubles stand in the way of your doing the things you want to do?"(TROUBLE). The...
journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/s1041610202008165
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Differentiating Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), two of the commonest forms of dementia in older age, remains a diagnostic challenge. To assist with better understanding of the differences between the conditions during life, we assessed limbic and subcortical brain volumes in AD,...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610215001805
更新日期:2016-04-01 00:00:00
abstract::ABSTRACTObjectives:The objectives of the study were to examine the trajectory of spirituality among older adults, to investigate the roles of gender and religion on the developmental trajectory of spirituality, and to explore whether the linear growth of spirituality accelerated or decelerated at time points at which ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218000029
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Suicide is a major public health concern. The elderly have the highest rate of suicide and they make more lethal suicide attempts and have fewer psychiatric interventions than young people. Furthermore, they have old-age specific psychosocial difficulties. The present study investigated psychosocial risk fac...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211000263
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:There has been an increasing interest in the relationship between severity of disease and costs in the care of people with dementia. Much of the current evidence is based on cross-sectional data, suggesting the need to examine trends over time for this important and growing cohort of the population. METHODS...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610214002063
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:This study was conducted to estimate prevalence rates and risk factors for late-life depression in a large nationwide representative sample from Taiwan. METHODS:A total of 5,664, randomly sampled individuals aged ≥55 years were enrolled. Clinically, relevant depressive symptoms were classified using the Cen...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217000199
更新日期:2017-07-01 00:00:00
abstract::ABSTRACTObjectives:Behavioral and psychological symptoms of dementia (BPSD) are nearly universal in dementia, a condition occurring in more than 40 million people worldwide. BPSD present a considerable treatment challenge for prescribers and healthcare professionals. Our purpose was to prioritize existing and emerging...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218000534
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:The study of predeath grief is hampered by measures that are often lengthy and not clearly differentiated from other caregiving outcomes, most notably burden. We aimed to validate a new 11-item Caregiver Grief Questionnaire (CGQ) assessing two dimensions of predeath grief, namely relational deprivation and em...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610219000309
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:While dementia is more common in older people and suicide rates in many countries are higher among the elderly, there is some doubt about the association between these two phenomena. METHODS:A search of the major relevant databases was carried out to examine the evidence for this possible association. RESU...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610209009065
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Previous studies have thoroughly investigated the prevalence and risk factors for completed suicide. In marked contrast is the lack of a better understanding of attempted suicide in the elderly. The aim of this study was to estimate the prevalence of attempted suicide in the elderly and examine the associate...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610216002283
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Although interpersonal interactions are thought to affect psychopathology in schizophrenia, there is a paucity of data about how older adults with schizophrenia manage interpersonal conflicts. This paper examines interpersonal conflict strategies and their impact on positive symptom remission in older adults...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212001093
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The Geriatric Anxiety Inventory (GAI) was developed for assessing anxiety in older adults. The objectives of this work were: (a) to analyze the psychometric properties of the Spanish version of the GAI, and (b) to explore the associations between anxiety and other variables related to emotional distress (dep...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211001505
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:To examine the effects of complex cognitive (mahjong) and physical (Tai Chi) activities on dementia severity in nursing home residents with dementia. METHODS:Cluster-randomized open-label controlled design. 110 residents were randomized by nursing home into three conditions: mahjong, Tai Chi, and simple han...
journal_title:International psychogeriatrics
pub_type: 杂志文章,随机对照试验
doi:10.1017/S1041610213002524
更新日期:2014-04-01 00:00:00
abstract::Health-related quality of life (HRQL) was investigated in 211 inhabitants of five residential homes in The Netherlands and was assessed again 1 year later. It was examined (a) if HRQL was related to the presence of specific general medical illnesses, (b) if comorbidity resulted in poorer HRQL, independent of the type ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610299006067
更新日期:1999-12-01 00:00:00