Abstract:
OBJECTIVES:Geriatric depression complicates cognitive health in older adults. This study aims to investigate the impact of depressive symptoms on cognitive impairment in community-dwelling older adults, depending on whether cognitive dysfunction accompanied. DESIGN:A community-based longitudinal cohort study. SETTING:This study analyzed data from the Korean Longitudinal Study of Aging (KLoSA) from 2006 to 2018. PARTICIPANTS:Among 10,254 individuals who were registered in the KLoSA study, a total of 9119 subjects met the criteria, and 4547 subjects were included in the final analysis. The subjects were grouped into 4 categories based on depressive symptoms and cognitive dysfunction at baseline assessment: "normal control" (NC, n = 3341), "depression only" (Dep-only, n = 652), "cognitive dysfunction only" (CD-only, n = 393), and "depression with cognitive dysfunction" (Dep-CD, n = 161). MEASUREMENTS:Cognitive impairment 10 years later was defined as K-MMSE scores below two percentile on demographically adjusted norms. RESULTS:Ten-year survival, that is, not experiencing cognitive impairment, was 80 $$ \pm \,$$1% in NC group, 72 $$ \pm $$ 2% in Dep-only group, 52 $$ \pm $$ 3% in CD-only group, and 44 $$ \pm $$ 5% in Dep-CD group. The hazard ratio (HR) of the Dep-only group (HR = 1.18, 95% CI, 0.97-1.43, n.s.) did not differ from that of the NC group, but the HR of the Dep-CD group was significantly higher (HR = 2.85, 95% CI, 2.23-3.66, p < 0.001) than the NC group. When the Dep-CD group was compared to the CD-only group, the HR was 1.13 (95% CI, 0.85-1.49, n.s.), which indicates that it did not significantly differ from the CD-only group. CONCLUSIONS:Our findings suggest that depressive symptoms with cognitive dysfunction are associated with a higher risk of cognitive impairment. Furthermore, cognitive dysfunction occurring with depressive symptoms is as much a risk for cognitive impairment as is pure cognitive dysfunction. Thus, healthcare providers should pay close attention to the community-dwelling elderly when depressive symptoms occur with cognitive dysfunction.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Shin Mdoi
10.1017/S1041610220003622subject
Has Abstractpub_date
2020-11-16 00:00:00pages
1-11eissn
1041-6102issn
1741-203Xpii
S1041610220003622pub_type
杂志文章abstract:BACKGROUND:There are difficulties in accurately defining patients with vascular dementia (VaD) and, therefore, little is known about the characteristics of this population. OBJECTIVE:To examine the population characteristics in patients with VaD enrolled in two randomized, double-blind, placebo-controlled, 24-week cli...
journal_title:International psychogeriatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/S1041610203009190
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Few current studies explore psychological well-being among older Chinese immigrants in Australia. The study addressed this gap and provided preliminary data on psychological well-being among this group. Four indicators, namely depression, anxiety, loneliness, and quality of life, were used to present a compr...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610216001010
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Frailty is a complex health state of increased vulnerability associated with adverse outcomes such as disability, falls, hospitalization, and death. Along with physical impairments, cognition and quality of life may be affected in frail older adults. Yet, evidence is still lacking. The aim of this study was ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212000634
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:The use of benzodiazepines is associated with increased risk of fall-related injuries in the elderly. However, it is unclear if the risks vary across the products and how they depend on the pattern of use and dosage. Specifically, the possibility of cumulative effects of past benzodiazepine use has not been ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211002031
更新日期:2012-04-01 00:00:00
abstract::I read with great interest the study of Petrazzuoli et al. (2017) on exploring dementia management attitudes in primary care. The authors made a laudable effort to evaluate this important issue, which certainly needs timely attention. The high response rate from 25 member countries of the European General Practice Res...
journal_title:International psychogeriatrics
pub_type: 评论,信件
doi:10.1017/S1041610217003003
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Children of patients with young onset dementia (YOD) who are confronted with a parent who has a progressive disease, often assist in caregiving tasks, which may have a great impact on their lives. The objective of the present study is to explore the experiences of children living with a young parent with dem...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213001890
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:An association between metabolic syndrome (MetS) and disturbances in neurocognitive function has been identified in Caucasians but the nature and extent of impaired cognition in Asian MetS patients, who may be at greater risk of degenerative cognitive decline, remains unspecified. METHODS:A cross-sectional ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021400057X
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVES:To investigate the effect of a social robot intervention on depression, loneliness, and quality of life of older adults in long-term care (LTC) and to explore participants' experiences and perceptions after the intervention. DESIGN:A mixed-methods approach consisting of a single group, before and after quas...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610220000459
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:In dementia, cognitive and psychological disorders might interfere with maintaining social interactions. We have little information about the nature of these interactions of people with dementia in nursing homes. The aim of this study is to investigate social interactions between people with dementia and to ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610215002483
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To review the currently available data on the use of ketamine in the treatment of depression among older adults from randomized controlled studies. DESIGN:Randomized controlled trials. SETTING:Variable. PARTICIPANTS:60 years and older with depression. INTERVENTION:Ketamine. MEASUREMENTS:Change in Montgom...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610220000903
更新日期:2020-06-30 00:00:00
abstract:BACKGROUND:The clinical presentations in dementia with Lewy bodies (DLB) and frontotemporal dementia (FTD) overlap considerably with that of Alzheimer's disease (AD) despite different pathological processes. Autopsy studies have also shown that multiple brain pathology occurs frequently, even in cases with a single cli...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209009454
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Quality of Life-Alzheimer's Disease (QOL-AD) is a widely used scale for the study of quality of life in patients with dementia. The aim of this study is the transcultural adaptation and validation of the QOL-AD scale in Portugal. METHODS:Translation and transcultural adaptation was performed according to st...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213000379
更新日期:2013-07-01 00:00:00
abstract::ABSTRACT Background: The association between disability and depression is complex, with disability well established as a correlate and consequence of late life depression. Studies in community samples report that greater volumes of cerebral white matter hyperintensities (WMHs) seen on brain imaging are linked with fun...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610214000829
更新日期:2014-05-09 00:00:00
abstract::Few instruments are available with which to measure behavioral and psychological signs and symptoms in Hispanic patients with dementia. Therefore, the aim of the current study was to develop and evaluate a 17-item scale adapted from the Revised Memory and Behavior Problems Checklist. This measure, the Behavior Problem...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610201007438
更新日期:2001-03-01 00:00:00
abstract:OBJECTIVES:To quantitatively synthesize data on the accuracy of the Rowland Universal Dementia Assessment Scale (RUDAS) in different sociocultural settings and compare its performance to other brief screening instruments for the detection of dementia. DESIGN:Systematic review and meta-analysis. Literature searches wer...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610220000344
更新日期:2020-09-01 00:00:00
abstract::ABSTRACTBackground:Walking ability recently emerged as a sub-clinical marker of cognitive decline. Hence, the relationship between baseline gait and future cognitive decline was examined in geriatric patients. Because a "loss of complexity" (LOC) is a key phenomenon of the aging process that exhibits in multiple syste...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217002770
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Few studies have estimated care burden in large, representative, multi-ethnic Asian population-based informal caregivers of older adults with care needs. This study describes informal caregivers' care participation for a population-based sample of older adults with care needs in Singapore, investigates diffe...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021500160X
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Neuropsychiatric symptoms (NPS) are highly prevalent among nursing home patients with dementia. Several studies have investigated subsyndromes of NPS but the stability of these subsyndromes over time has rarely been examined. We have examined the stability over time of the factor structure of the Neuropsychi...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021100086X
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Dementia caregiving has been linked to negative consequences for mental health in caregivers. Although depression seems to be an enduring psychological consequence associated with caregiving, little is known about the longitudinal effects that modulating variables related to coping strategies have on caregiv...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211002237
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:A past history of self-harm is a significant risk factor for suicide in older people. The aims of this study are to (i) characterize older people who present with self-harm to emergency departments (EDs); and (ii) determine the predictors for repeat self-harm and suicide. METHODS:Demographic and clinical da...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217000308
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:The growing and welcome interest in the issues leading to distress and impairment in younger doctors has not been mirrored by a focus on the similar issues in older doctors which is surprising given the aging medical workforce. OBJECTIVES:To improve understanding of impairment in older doctors and to facili...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610207005431
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVES:People with dementia can face barriers when trying to access care after a diagnosis, particularly in young-onset dementia (YOD). Little is known about the effects of ethnicity on the use of anti-dementia medication and variations between age groups. The aim of this study was to analyze national data on varia...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610220000794
更新日期:2020-06-02 00:00:00
abstract:BACKGROUND:The study aimed to evaluate the Cognitive Assessment Battery (CAB) in a specialist clinic setting in order to find out if it if it could be a supplement to the Mini-mental State Examination (MMSE) and distinguish between normal aging, mild cognitive impairment (MCI) and dementia, as well as MCI of different ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210002334
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:Despite delirium being common in older hospitalized people, little is known about its management. The aims of this study are (1) to describe the pharmacological management of delirium in an acute care setting as a baseline measure prior to the implementation of newly developed Australian guidelines; and (2) t...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610208008028
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Clinical guidelines have the potential to assist in the management of aggression in dementia. This study aims to develop a conceptual framework for the construction of individualized guidelines for this group. METHODS:A concept map of the topic "How to manage aggression in dementia" was developed by reviewi...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212000014
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:A single-item depression measure may not be adequate in capturing the complex entity of mental health, despite wide use of this indicator in community studies. This study evaluated the accuracy of a single-question depression measure in comparison to two composite indices-the Center for Epidemiologic Studies...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217001673
更新日期:2018-01-01 00:00:00
abstract::In this review, we explore the relationship between epilepsy and cognition and between epilepsy and dementia. Chronic epilepsy, particularly mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis, may be associated with impaired cognition, which can be secondary to uncontrolled seizures, to adverse effects of...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/s1041610205002024
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Sleep disturbance is common in caregivers of older adults with memory disorders. Little is known, however, about the implications of caregivers' poor sleep with regard to their physical functioning. METHODS:In this cross-sectional study, we investigated the association between objectively measured sleep and...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209991153
更新日期:2010-03-01 00:00:00
abstract::The authors conducted a survey of members of the International Psychogeriatric Association (IPA) to determine the state of development of both the profession of geriatric psychiatry and services for mentally ill elderly. Ratings for both issues were based on a scale of 1 to 4, with 1 being little to no development and...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610298005444
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:This study aimed to explore the experiences and challenges of informal caregivers in Singapore with the intent of identifying the multi-dimensional unmet needs from their perspective and generating caregivers' needs checklist based on the findings. METHODS:Informal caregivers were relatives of people with d...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213001051
更新日期:2013-10-01 00:00:00