Abstract:
:The statements produced by the Consensus Conference on Diverticular Disease promoted by GRIMAD (Gruppo Italiano Malattia Diverticolare, Italian Group on Diverticular Diseases) are reported. Topics such as epidemiology, risk factors, diagnosis, medical and surgical treatment of diverticular disease (DD) in patients with uncomplicated and complicated DD were reviewed by a scientific board of experts who proposed 55 statements graded according to level of evidence and strength of recommendation, and approved by an independent jury. Each topic was explored focusing on the more relevant clinical questions. Comparison and discussion of expert opinions, pertinent statements and replies to specific questions, were presented and approved based on a systematic literature search of the available evidence. Comments were added explaining the basis for grading the evidence, particularly for controversial areas.
journal_name
United European Gastroenterol Jjournal_title
United European gastroenterology journalauthors
Cuomo R,Barbara G,Pace F,Annese V,Bassotti G,Binda GA,Casetti T,Colecchia A,Festi D,Fiocca R,Laghi A,Maconi G,Nascimbeni R,Scarpignato C,Villanacci V,Annibale Bdoi
10.1177/2050640614547068subject
Has Abstractpub_date
2014-10-01 00:00:00pages
413-42issue
5eissn
2050-6406issn
2050-6414pii
10.1177_2050640614547068journal_volume
2pub_type
杂志文章abstract:BACKGROUND:Patients with primary oesophageal squamous cell carcinoma are at risk of developing multiple primary tumours in the upper aero digestive tract. To date, most studies are performed in the Asian population. We aimed to evaluate the risk of multiple primary tumours in the upper aero digestive tract and stomach ...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640620977129
更新日期:2020-12-03 00:00:00
abstract:Background:Endoscopic mucosal resection is well-established for resecting flat or sessile benign colon polyps. The novel underwater endoscopic mucosal resection eschews submucosal injection prior to endoscopic mucosal resection. Reports about underwater endoscopic mucosal resection were limited to small series of singl...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640617733923
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Reliable and safe sedation is a prerequisite for endoscopic interventions. The current standard is rather safe, yet, an objective device to measure sedation depth is missing. To date, anaesthesia monitors based on processed electroencephalogram (EEG) have not been utilised in conscious sedation. OBJECTIVE:T...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640620959153
更新日期:2020-09-14 00:00:00
abstract:Background:Sporadic nonampullary duodenal adenocarcinoma is a rare malignant neoplasm in which poor prognosis is often associated with delayed diagnosis. Objective:A case-control study was designed to evaluate the clinical and endoscopic characteristics of patients with nonampullary duodenal epithelial tumours (NADETs...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640618817689
更新日期:2019-03-01 00:00:00
abstract:Background:Over the past decades, multiple approaches to aspiration sclerotherapy of large symptomatic hepatic cysts have been investigated. However, comparative data are scarce. Objective:The objective of this article is to compare cyst reduction, symptomatic relief, and adverse events between ethanol sclerotherapy a...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640618764940
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Patients with Crohn's disease (CD) frequently complain of cognitive difficulties such as problems with concentration and clouding of thought, yet this has scarcely been objectively defined and underlying mechanisms remain unknown. OBJECTIVE:The objective of this article is to objectively measure cognitive i...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640616663397
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Prevalence estimates for celiac disease (CD) depend on the method used. The role of deamidated gliadin peptide (DGP) and genetic testing in epidemiological studies and diagnostic settings of celiac disease (CD) has still to be established. OBJECTIVES:The objective of this article is to assess the prevalence...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640615569379
更新日期:2015-04-01 00:00:00
abstract:Background:Since introduction of the MELD score in the liver allograft allocation system, renal insufficiency has emerged as an increasing problem. Here we evaluated the course of kidney function in patients with advanced renal insufficiency prior to liver transplantation (LT). Methods:A total of 254 patients undergoi...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640617707089
更新日期:2018-02-01 00:00:00
abstract::The European Society of Gastrointestinal Endoscopy (ESGE) and United European Gastroenterology (UEG) have a vision to create a thriving community of endoscopy services across Europe, collaborating with each other to provide high quality, safe, accurate, patient-centered and accessible endoscopic care. Whilst the bound...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640615624631
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Primary bile acid diarrhoea (BAD) is associated with increased bile acid synthesis and low fibroblast growth factor 19 (FGF19). Bile acid sequestrants are used as therapy, but are poorly tolerated and may exacerbate FGF19 deficiency. AIM:The purpose of this study was to evaluate the pharmacological effects ...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640616662432
更新日期:2017-04-01 00:00:00
abstract:Background and aims:The aim of this survey was to find out whether the perspectives of patients with inflammatory bowel disease concerning biosimilars have changed since the publication of our last survey carried out in 2014-2015. Methods:An online survey consisting of 19 questions was made available by the European F...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640619883704
更新日期:2019-12-01 00:00:00
abstract:Background:Cortiment®MMX® (budesonide MMX®) is currently approved for the induction of remission in mild-to-moderate ulcerative colitis (UC) patients when 5-ASA treatment is not sufficient. Data in real-life settings are lacking. Methods:This was a multicentre observational prospective cohort study conducted in Europe...
journal_title:United European gastroenterology journal
pub_type: 杂志文章,多中心研究
doi:10.1177/2050640619864848
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Sphingosine kinase 1 (SphK1)/sphingosine-1-phosphate (S1P)/sphingosine-1-phosphate receptors (S1PRs) signaling plays a key role in inflammatory responses. Lei et al. showed that SphK1 inhibition presented a hepatoprotective effect on acute liver damage via decreasing hepatic high-mobility group box 1 (HMGB1)...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640616637968
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Prucalopride is a selective, high-affinity, 5-hydroxytryptamine (serotonin) type 4 (5-HT4) receptor agonist with gastrointestinal prokinetic activities. This integrated analysis of data from three double-blind phase III trials (ClinicalTrials.gov: NCT00488137, NCT00483886, NCT00485940) compared the efficacy ...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640612474651
更新日期:2013-02-01 00:00:00
abstract:Background:Recent studies suggest that the prevalence of celiac disease is rising. We previously established the prevalence of celiac disease in healthy blood donors in 2002. Objective:The purpose of this study was to examine whether the prevalence of celiac disease and celiac disease autoimmunity has changed over tim...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640618818227
更新日期:2019-04-01 00:00:00
abstract::Stricturing Crohn's disease (CD) is a significant clinical problem. The presence of a stricture may be suggested by clinical symptoms. Cross-sectional imaging using computed tomography or magnetic resonance enterography is essential in diagnosing strictures as it allows further characterization and evaluation for comp...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640620901960
更新日期:2020-04-01 00:00:00
abstract:Background:Barrett's esophagus (BE) is rare in African Americans (AA). However, the risk difference magnitude in histologic BE prevalence between AA and non-Hispanic whites (nHw) has not been quantified to date. Objective:The objective of this article is to determine the degree of histologic BE risk difference between...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640617707862
更新日期:2018-02-01 00:00:00
abstract:Background:Dysplasia in Barrett's esophagus (BE) biopsies is associated with low observer agreement among general pathologists. Therefore, expert review is advised. We are developing a web-based, national expert review panel for histological review of BE biopsies. Objective:The aim of this study was to create benchmar...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640618764710
更新日期:2018-07-01 00:00:00
abstract:INTRODUCTION:Because of their many advantages, faecal immunochemical tests (FIT) are superseding traditional guaiac-based faecal occult blood tests in bowel screening programmes. METHODS:A quantitative FIT was adopted for use in two evaluation National Health Service (NHS) Boards in Scotland using a cut-off faecal hae...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640613489281
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To determine the survival outcome and prognostic factors of hepatocellular carcinoma (HCC) survival in patients who underwent radiofrequency ablation (RFA). METHODS:The Surveillance, Epidemiology and End Results (SEER) database was queried: There were 2588 HCC patients from 2004 to 2012 who underwent RFA. Th...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640616659024
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Diagnosing coeliac disease (CD) in patients on a gluten-free diet (GFD) is difficult. Ingesting gluten elevates circulating interleukin (IL)-2, IL-8 and IL-10 in CD patients on a GFD. OBJECTIVE:We tested whether cytokine release after gluten ingestion differentiates patients with CD from those with self-rep...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640619874173
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND AND AIMS:The aim of this study was to determine the mortality and re-bleeding rates, and the risk factors involved, in a cohort of patients with previous diverticular bleeding (DB). METHODS:In 2007, data on 2462 patients with lower gastrointestinal (GI) bleeding were collected prospectively at several Frenc...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640616647816
更新日期:2017-02-01 00:00:00
abstract:Background:There is no consensus on what constitutes adequate training for needle knife precut sphincterotomy. Objective:The purpose of this study was to determine the number of procedures required before effective and safe precut sphincterotomy can be achieved. Methods:This retrospective study examined the cumulativ...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640617701808
更新日期:2017-12-01 00:00:00
abstract::Ineffective esophageal motility (IEM) is the most frequently encountered esophageal motility disorder. Patients may present with a variety of symptoms, such as dysphagia, heartburn, odynophagia, and regurgitation. Over the past years, the landscape of esophageal motility testing has been revolutionized; however, our c...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640615585688
更新日期:2015-06-01 00:00:00
abstract:Introduction:Endoscopic mucosal resection and endoscopic submucosal dissection are demanding procedures. This study aims to establish face, content and expert validity of the live porcine model in performing endoscopic mucosal resection, endoscopic submucosal dissection, complication management and to assess it as a tr...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640617742484
更新日期:2018-05-01 00:00:00
abstract::The human microbiota exerts multiple physiological functions such as the regulation of metabolic and inflammatory processes. High-throughput sequencing techniques such as next-generation sequencing have become widely available in preclinical and clinical settings and have exponentially increased our knowledge about th...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640620944720
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Eosinophilic oesophagitis (EoO) has been associated with allergic disorders as well as aeroallergens. The current literature has shown a possible association between seasonal variation, mainly in the spring, and the incidence of EoO. However, this data was based on small population studies that did not exclu...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640614525152
更新日期:2014-04-01 00:00:00
abstract:Background:Intestinal microbiota and their metabolites (e.g. short-chain fatty acids (SCFAs)) may influence nonalcoholic fatty liver disease (NAFLD). Objective:The objective of this article is to analyze gut bacterial diversity together with fecal SCFA concentrations and immunophenotyping of peripheral blood in histol...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640618804444
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND AND AIM:The efficacy of clipping for preventing delayed bleeding after colorectal endoscopic resection is still controversial. To assess the efficacy of prophylactic clipping, we conducted a meta-analysis of randomized controlled trials. METHODS:We searched PubMed, the Cochrane library, and the Igaku-chuo-z...
journal_title:United European gastroenterology journal
pub_type: 杂志文章,评审
doi:10.1177/2050640616687837
更新日期:2017-10-01 00:00:00
abstract::Eosinophilic esophagitis (EoE) is an emerging esophageal inflammatory disorder affecting children and young adults. As a relatively new disease, EoE is still burdened by frequent diagnostic and therapeutic pitfalls in clinical practice. This manuscript posits a number of similarities with Crohn's disease, which may he...
journal_title:United European gastroenterology journal
pub_type: 杂志文章,评审
doi:10.1177/2050640616672953
更新日期:2017-10-01 00:00:00