Effects of conventional and a novel colonic-release bile acid sequestrant, A3384, on fibroblast growth factor 19 and bile acid metabolism in healthy volunteers and patients with bile acid diarrhoea.

abstract：BACKGROUND:Biologically naïve patients with inflammatory bowel disease treated with vedolizumab (VDZ) are largely underrepresented in real-world cohorts. A multi-centre, observational cohort study was performed on the effectiveness and safety of VDZ in biologically naïve subjects with Crohn's disease (CD) and ulcerativ...

journal_title：United European gastroenterology journal

authors： Macaluso FS,Fries W,Renna S,Viola A,Muscianisi M,Cappello M,Guida L,Siringo S,Camilleri S,Garufi S,Privitera AC,Belluardo N,Giangreco E,Bertolami C,Vassallo R,Rizzuto G,Orlando R,Ventimiglia M,Orlando A,Sicilian Net

更新日期：2020-11-01 00:00:00

abstract：:Barrett's oesophagus is a pre-malignant condition associated with the development of oesophageal adenocarcinoma. Currently white light endoscopy and biopsy is the mainstay diagnostic tool. Yet this approach is troubled by issues related to cumbersome biopsy sampling, biopsy sampling errors and cost. Therefore in order...

journal_title：United European gastroenterology journal

authors： Sharma N,Srivastava S,Kern F,Xian W,Ming T,McKeon F,Ho KY

更新日期：2016-12-01 00:00:00

abstract：Background:Dysplasia in Barrett's esophagus (BE) biopsies is associated with low observer agreement among general pathologists. Therefore, expert review is advised. We are developing a web-based, national expert review panel for histological review of BE biopsies. Objective:The aim of this study was to create benchmar...

journal_title：United European gastroenterology journal

authors： van der Wel MJ,Duits LC,Klaver E,Pouw RE,Seldenrijk CA,Offerhaus G,Visser M,Ten Kate F,Tijssen JG,Bergman J,Meijer SL

更新日期：2018-07-01 00:00:00

abstract：:Stricturing Crohn's disease (CD) is a significant clinical problem. The presence of a stricture may be suggested by clinical symptoms. Cross-sectional imaging using computed tomography or magnetic resonance enterography is essential in diagnosing strictures as it allows further characterization and evaluation for comp...

journal_title：United European gastroenterology journal

authors： El Ouali S,Click B,Holubar SD,Rieder F

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The risk of esophageal adenocarcinoma (EAC) in non-dysplastic Barrett's esophagus (NDBE) is considered to be approximately 0.3% per year or even lower, according to population-based studies. Data from countries with low EAC incidence are scarce. Our principal aim was to determine the incidence of high-grade ...

journal_title：United European gastroenterology journal

authors： Pereira AD,Chaves P

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Multiple medications are associated with an increased risk of incident hepatic encephalopathy. Despite this known risk, medications such as opioids, benzodiazepines, gabapentin/pregabalin, and/or proton pump inhibitors are increasingly prescribed to persons with cirrhosis. Deprescribing is a promisi...

journal_title：United European gastroenterology journal

authors： Williams S,Louissaint J,Nikirk S,Bajaj JS,Tapper EB

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:Acute upper abdominal pain is a frequent symptom leading to hospital admission. OBJECTIVE:To determine whether a primary intra- and extraluminal diagnostic approach enabled by endoscopic ultrasound is as effective as a conventional diagnostic algorithm of transabdominal ultrasound followed by oesophagogastr...

journal_title：United European gastroenterology journal

authors： Jung A,Schlag C,Becker V,von Delius S,Lersch C,Jeliazkova P,Herner A,Bajbouj M,Schuster T,Meining A

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:Malignant vascular tumors of the liver are rare. The aim of this study was to investigate the applicability of gray scale and contrast-enhanced ultrasonography in patients with epithelioid hemangioendothelioma (EHE) of the liver and hepatic angiosarcoma (HA) and to describe the clinical presentation. METHOD...

journal_title：United European gastroenterology journal

authors： Schweitzer N,Soudah B,Gebel M,Manns MP,Boozari B

更新日期：2015-02-01 00:00:00

abstract：Objective:The objective of this article is to evaluate the relationship between off-hours hospital admission (weekends, public holidays or nighttime) and mortality for upper gastrointestinal hemorrhage (UGIH). Methods:Medline, Embase, Scopus, and the Chinese Biomedical Literature were searched through December 2016 to...

journal_title：United European gastroenterology journal

authors： Xia XF,Chiu PWY,Tsoi KKF,Chan FKL,Sung JJY,Lau JYW

更新日期：2018-04-01 00:00:00

abstract：:The human microbiota exerts multiple physiological functions such as the regulation of metabolic and inflammatory processes. High-throughput sequencing techniques such as next-generation sequencing have become widely available in preclinical and clinical settings and have exponentially increased our knowledge about th...

journal_title：United European gastroenterology journal

authors： Ammer-Herrmenau C,Pfisterer N,Weingarten MF,Neesse A

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Some studies have explored the prevalence of pancreatic cystic lesions (PCLs). Only one study based on magnetic resonance imaging (MRI) report examination focused specifically on intraductal papillary mucinous neoplasm (IPMN) in a European general population. The aim of this study was to evaluate th...

journal_title：United European gastroenterology journal

authors： Laurent L,Vullierme MP,Rebours V,Maire F,Hentic O,Francoz C,Durand F,Ruszniewski P,Lévy P

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Women conceiving following in vitro fertilization (IVF) likely have a variety of risk factors that predispose them to gastroesophageal reflux disease (GERD) in the future. OBJECTIVE:We aimed to investigate whether pregnancy through IVF may predispose to subsequent GERD compared with pregnancies without IVF....

journal_title：United European gastroenterology journal

authors： Turan I,Kitapcioglu G,Tavmergen Goker E,Sahin G,Bor S,Ege Reflux Study Group.

更新日期：2016-04-01 00:00:00

abstract：Introduction:Endoscopic mucosal resection and endoscopic submucosal dissection are demanding procedures. This study aims to establish face, content and expert validity of the live porcine model in performing endoscopic mucosal resection, endoscopic submucosal dissection, complication management and to assess it as a tr...

journal_title：United European gastroenterology journal

authors： Küttner-Magalhães R,Dinis-Ribeiro M,Bruno MJ,Marcos-Pinto R,Rolanda C,Koch AD

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Patients with primary oesophageal squamous cell carcinoma are at risk of developing multiple primary tumours in the upper aero digestive tract. To date, most studies are performed in the Asian population. We aimed to evaluate the risk of multiple primary tumours in the upper aero digestive tract and stomach ...

journal_title：United European gastroenterology journal

authors： van de Ven SE,Falger JM,Verhoeven RH,Baatenburg de Jong RJ,Spaander MC,Bruno MJ,Koch AD

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND AND AIMS:The search for a source of gastrointestinal bleeding is associated with two distinct approaches of trying to rule in a specific diagnosis or rule out any potential source of bleeding. The study aim was to understand the conceptual differences underlying the two searches. METHODS:The performance of ...

journal_title：United European gastroenterology journal

authors： Sonnenberg A

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Sphingosine kinase 1 (SphK1)/sphingosine-1-phosphate (S1P)/sphingosine-1-phosphate receptors (S1PRs) signaling plays a key role in inflammatory responses. Lei et al. showed that SphK1 inhibition presented a hepatoprotective effect on acute liver damage via decreasing hepatic high-mobility group box 1 (HMGB1)...

journal_title：United European gastroenterology journal

authors： Tian T,Tian W,Yang F,Zhao R,Huang Q,Zhao Y

更新日期：2016-10-01 00:00:00

abstract：Background:Cortiment®MMX® (budesonide MMX®) is currently approved for the induction of remission in mild-to-moderate ulcerative colitis (UC) patients when 5-ASA treatment is not sufficient. Data in real-life settings are lacking. Methods:This was a multicentre observational prospective cohort study conducted in Europe...

journal_title：United European gastroenterology journal

authors： Danese S,Hart A,Dignass A,Fiorino G,Louis E,Bonovas S,D'Haens G,Dotan I,Rogler G,Paridaens K,Peyrin-Biroulet L

更新日期：2019-11-01 00:00:00

abstract：:Fistulas and fibrosis or strictures represent frequent complications in irritable bowel disease (IBD) patients. To date, treatment options for fistulas are limited and surgery is often required. Similarly, no preventive treatment for fibrosis and stricture formation has been established. Frequently, stricture formatio...

journal_title：United European gastroenterology journal

authors： Scharl M,Bruckner RS,Rogler G

更新日期：2016-08-01 00:00:00

abstract：Background:Barrett's esophagus (BE) is rare in African Americans (AA). However, the risk difference magnitude in histologic BE prevalence between AA and non-Hispanic whites (nHw) has not been quantified to date. Objective:The objective of this article is to determine the degree of histologic BE risk difference between...

journal_title：United European gastroenterology journal

authors： Alkaddour A,Palacio C,Vega KJ

更新日期：2018-02-01 00:00:00

abstract：Background:Endoscopic mucosal resection is well-established for resecting flat or sessile benign colon polyps. The novel underwater endoscopic mucosal resection eschews submucosal injection prior to endoscopic mucosal resection. Reports about underwater endoscopic mucosal resection were limited to small series of singl...

journal_title：United European gastroenterology journal

authors： Cadoni S,Liggi M,Gallittu P,Mura D,Fuccio L,Koo M,Ishaq S

更新日期：2018-04-01 00:00:00

abstract：Background:Antibiotic-associated colitis caused by Clostridium difficile (C. difficile) is the most common cause of hospital-acquired diarrhea. The pathogenesis of C. difficile colitis is mediated by bacterial toxins. C. difficile infection (CDI) severity may be determined by the fecal level of these toxins. Objective...

journal_title：United European gastroenterology journal

authors： Cohen NA,Miller T,Na'aminh W,Hod K,Adler A,Cohen D,Guzner-Gur H,Santo E,Halpern Z,Carmeli Y,Maharshak N

更新日期：2018-06-01 00:00:00

abstract：Background:The need for a blood transfusion, defined as hemoglobin < 70 g/L, is the measure for assessing the risk levels in patients with upper gastrointestinal bleeding (UGIB). However, not all patients with a low hemoglobin level have a poor prognosis. Objective:We assessed the clinical predictive factors associate...

journal_title：United European gastroenterology journal

authors： Horibe M,Ogura Y,Matsuzaki J,Kaneko T,Yokota T,Okawa O,Nakatani Y,Iwasaki E,Nishizawa T,Hosoe N,Masaoka T,Yahagi N,Namiki S,Kanai T

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The 2016, United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis (HaPanEU) provided evidence-based recommendations for the management of chronic pancreatitis and allowed for the objective evaluation of the quality of care in several doma...

journal_title：United European gastroenterology journal

authors： de Rijk FE,Kempeneers MA,Bruno MJ,Besselink MG,van Goor H,Boermeester MA,van Geenen EJ,van Hooft JE,van Santvoort HC,Verdonk RC,Dutch Pancreatitis Study Group.

更新日期：2020-08-01 00:00:00

abstract：Background:Hepatic encephalopathy is associated with altered gut microbiota. Proton pump inhibitors increase the risk of small bowel bacterial overgrowth. Objectives:This was a case-control study aimed at exploring the relationship of proton pump inhibitor use with the risk of hepatic encephalopathy during hospitaliza...

journal_title：United European gastroenterology journal

authors： Zhu J,Qi X,Yu H,Yoshida EM,Mendez-Sanchez N,Zhang X,Wang R,Deng H,Li J,Han D,Guo X

更新日期：2018-10-01 00:00:00

abstract：Background:Very few data regarding the use of infliximab in children with very early-onset inflammatory bowel disease (VEO-IBD) have been reported. Objective:We aimed to assess the efficacy and the safety of infliximab in children with VEO-IBD compared with older children. Methods:Children treated with infliximab wer...

journal_title：United European gastroenterology journal

authors： Bramuzzo M,Arrigo S,Romano C,Filardi MC,Lionetti P,Agrusti A,Dipasquale V,Paci M,Zuin G,Aloi M,Strisciuglio C,Miele E,Pastore M,Martelossi S,Alvisi P,SIGENP IBD Working Group.

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Autoimmune gastritis (AIG) and adenocarcinoma-associated chronic atrophic gastritis (CAG) are both associated with oxyntic atrophy, but AIG patients demonstrate an increased risk of carcinoid tumors rather than the elevated risk of adenocarcinoma observed with CAG. We therefore sought to compare the characte...

journal_title：United European gastroenterology journal

authors： Jeong S,Choi E,Petersen CP,Roland JT,Federico A,Ippolito R,D'Armiento FP,Nardone G,Nagano O,Saya H,Romano M,Goldenring JR

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Peroral endoscopic esophageal myotomy (POEM) represents a less invasive alternative, as compared with conventional laparoscopic Heller myotomy for treating achalasia patients. In the last years, a number of prospective and retrospective experiences with POEM use for achalasia have been published. METHODS:Re...

journal_title：United European gastroenterology journal

authors： Barbieri LA,Hassan C,Rosati R,Romario UF,Correale L,Repici A

更新日期：2015-08-01 00:00:00

abstract：:The statements produced by the Consensus Conference on Diverticular Disease promoted by GRIMAD (Gruppo Italiano Malattia Diverticolare, Italian Group on Diverticular Diseases) are reported. Topics such as epidemiology, risk factors, diagnosis, medical and surgical treatment of diverticular disease (DD) in patients wit...

journal_title：United European gastroenterology journal

authors： Cuomo R,Barbara G,Pace F,Annese V,Bassotti G,Binda GA,Casetti T,Colecchia A,Festi D,Fiocca R,Laghi A,Maconi G,Nascimbeni R,Scarpignato C,Villanacci V,Annibale B

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Prevalence estimates for celiac disease (CD) depend on the method used. The role of deamidated gliadin peptide (DGP) and genetic testing in epidemiological studies and diagnostic settings of celiac disease (CD) has still to be established. OBJECTIVES:The objective of this article is to assess the prevalence...

journal_title：United European gastroenterology journal

authors： Leja M,Shums Z,Nikitina-Zake L,Gavars M,Kikuste I,Milo J,Daugule I,Pahomova J,Pirags V,Dzerve V,Klovins J,Erglis A,Norman GL

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Detection of cholangiocarcinoma (CC) remains a diagnostic challenge particularly in patients with primary sclerosing cholangitis (PSC). We recently established diagnostic peptide marker models in bile and urine to detect CC. Our aim was to combine both models to reach a higher diagnostic accuracy of CC diagn...

journal_title：United European gastroenterology journal

authors： Voigtländer T,Metzger J,Schönemeier B,Jäger M,Mischak H,Manns MP,Lankisch TO

更新日期：2017-08-01 00:00:00