Abstract:
:Ineffective esophageal motility (IEM) is the most frequently encountered esophageal motility disorder. Patients may present with a variety of symptoms, such as dysphagia, heartburn, odynophagia, and regurgitation. Over the past years, the landscape of esophageal motility testing has been revolutionized; however, our current treatment options for IEM still remain limited. Previous studies have suggested that buspirone, a serotonin receptor agonist, enhances esophageal peristalsis and lower esophageal sphincter (LES) function. Recent work provides the first evidence that buspirone may influence LES resting pressure in patients with systemic sclerosis. Future research should evaluate whether the beneficial effects of buspirone also apply to the broad clinical entity of esophageal dysphagia patients with IEM.
journal_name
United European Gastroenterol Jjournal_title
United European gastroenterology journalauthors
Scheerens C,Tack J,Rommel Ndoi
10.1177/2050640615585688subject
Has Abstractpub_date
2015-06-01 00:00:00pages
261-5issue
3eissn
2050-6406issn
2050-6414pii
10.1177_2050640615585688journal_volume
3pub_type
杂志文章abstract:Background:Antibiotic-associated colitis caused by Clostridium difficile (C. difficile) is the most common cause of hospital-acquired diarrhea. The pathogenesis of C. difficile colitis is mediated by bacterial toxins. C. difficile infection (CDI) severity may be determined by the fecal level of these toxins. Objective...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640617750809
更新日期:2018-06-01 00:00:00
abstract:Background:Aspirin use may reduce the incidence of pancreatic cancer (PC), but no data are available regarding its chemopreventive effects on intraductal papillary mucinous neoplasm (IPMN). We aimed to determine whether low-dose aspirin (LDA) reduces PC development and morphological changes on imaging in IPMN patients....
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640617693524
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:Malignant vascular tumors of the liver are rare. The aim of this study was to investigate the applicability of gray scale and contrast-enhanced ultrasonography in patients with epithelioid hemangioendothelioma (EHE) of the liver and hepatic angiosarcoma (HA) and to describe the clinical presentation. METHOD...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640614560604
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Variable prevalence rates between 2.4 and 35% have been reported for chronic constipation across different countries worldwide, with a low 5% for Germany. OBJECTIVES AND METHODS:We conducted a computer-assisted telephone interview among 15,002 representative individuals in Germany, asking about health-relat...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640615603009
更新日期:2016-06-01 00:00:00
abstract::The human microbiota exerts multiple physiological functions such as the regulation of metabolic and inflammatory processes. High-throughput sequencing techniques such as next-generation sequencing have become widely available in preclinical and clinical settings and have exponentially increased our knowledge about th...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640620944720
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND AND AIMS:The aim of this study was to determine the mortality and re-bleeding rates, and the risk factors involved, in a cohort of patients with previous diverticular bleeding (DB). METHODS:In 2007, data on 2462 patients with lower gastrointestinal (GI) bleeding were collected prospectively at several Frenc...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640616647816
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND AND AIMS:Multiple medications are associated with an increased risk of incident hepatic encephalopathy. Despite this known risk, medications such as opioids, benzodiazepines, gabapentin/pregabalin, and/or proton pump inhibitors are increasingly prescribed to persons with cirrhosis. Deprescribing is a promisi...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640620975224
更新日期:2020-11-23 00:00:00
abstract::One of the aims of the Young Talent Group (YTG) is to make United European Gastroenterology (UEG) more attractive for young fellows interested in gastroenterology, and to involve them actively in UEG activities, by collaborating with young GI sections (YGIS) across Europe. Therefore, the YTG launched a survey to colle...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640617713936
更新日期:2017-08-01 00:00:00
abstract::Eosinophilic esophagitis (EoE) is an emerging esophageal inflammatory disorder affecting children and young adults. As a relatively new disease, EoE is still burdened by frequent diagnostic and therapeutic pitfalls in clinical practice. This manuscript posits a number of similarities with Crohn's disease, which may he...
journal_title:United European gastroenterology journal
pub_type: 杂志文章,评审
doi:10.1177/2050640616672953
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Sphingosine kinase 1 (SphK1)/sphingosine-1-phosphate (S1P)/sphingosine-1-phosphate receptors (S1PRs) signaling plays a key role in inflammatory responses. Lei et al. showed that SphK1 inhibition presented a hepatoprotective effect on acute liver damage via decreasing hepatic high-mobility group box 1 (HMGB1)...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640616637968
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Recent reports from western countries have indicated an increased incidence and a decreased mortality in acute pancreatitis. However, the incidence assessment has often been hampered by the inclusion of both first-time and recurrent episodes of acute pancreatitis. METHODS:In this retrospective cohort study,...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640620913737
更新日期:2020-05-01 00:00:00
abstract::Barrett's oesophagus is a pre-malignant condition associated with the development of oesophageal adenocarcinoma. Currently white light endoscopy and biopsy is the mainstay diagnostic tool. Yet this approach is troubled by issues related to cumbersome biopsy sampling, biopsy sampling errors and cost. Therefore in order...
journal_title:United European gastroenterology journal
pub_type: 杂志文章,评审
doi:10.1177/2050640615619281
更新日期:2016-12-01 00:00:00
abstract:INTRODUCTION:Patients with inflammatory bowel disease suffer from various symptoms, impairing their quality of life and often affecting psychosocial issues. This may lead to the need for additional psychological care. This study investigated patients' subjective need for integrated psychosomatic support and psychothera...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640620946874
更新日期:2020-07-28 00:00:00
abstract:Objective:The objective of this article is to evaluate the relationship between off-hours hospital admission (weekends, public holidays or nighttime) and mortality for upper gastrointestinal hemorrhage (UGIH). Methods:Medline, Embase, Scopus, and the Chinese Biomedical Literature were searched through December 2016 to...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640617732651
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:The risk of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infection and clinical outcomes of coronavirus disease (COVID-19) in inflammatory bowel disease are unclear. METHODS:We searched PubMed and Embase with the keywords: inflammatory bowel disease, Crohn's disease, ulcerative colit...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640620972602
更新日期:2020-11-19 00:00:00
abstract:Background:Barrett's esophagus (BE) is rare in African Americans (AA). However, the risk difference magnitude in histologic BE prevalence between AA and non-Hispanic whites (nHw) has not been quantified to date. Objective:The objective of this article is to determine the degree of histologic BE risk difference between...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640617707862
更新日期:2018-02-01 00:00:00
abstract:Background:The ability to predict the severity of disease is important to reduce morbidity and mortality in patients with acute pancreatitis (AP). Vitamin D deficiency has been associated with severity in various diseases. Objective:This study was conducted to assess vitamin D as a predictor of disease severity in pat...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640618811489
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:To determine the survival outcome and prognostic factors of hepatocellular carcinoma (HCC) survival in patients who underwent radiofrequency ablation (RFA). METHODS:The Surveillance, Epidemiology and End Results (SEER) database was queried: There were 2588 HCC patients from 2004 to 2012 who underwent RFA. Th...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640616659024
更新日期:2017-03-01 00:00:00
abstract::Crohn's disease (CD) is a chronic inflammatory bowel disease that usually progresses to bowel damage, defined as strictures, fistulas and abscesses. These complications require intestinal resection and lead to further irreversible structural damage. Cross-sectional imaging, such as magnetic resonance imaging, computed...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640620908696
更新日期:2020-05-01 00:00:00
abstract:Background:The need for a blood transfusion, defined as hemoglobin < 70 g/L, is the measure for assessing the risk levels in patients with upper gastrointestinal bleeding (UGIB). However, not all patients with a low hemoglobin level have a poor prognosis. Objective:We assessed the clinical predictive factors associate...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640618764161
更新日期:2018-06-01 00:00:00
abstract:Background:Since introduction of the MELD score in the liver allograft allocation system, renal insufficiency has emerged as an increasing problem. Here we evaluated the course of kidney function in patients with advanced renal insufficiency prior to liver transplantation (LT). Methods:A total of 254 patients undergoi...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640617707089
更新日期:2018-02-01 00:00:00
abstract:Background:Dysplasia in Barrett's esophagus (BE) biopsies is associated with low observer agreement among general pathologists. Therefore, expert review is advised. We are developing a web-based, national expert review panel for histological review of BE biopsies. Objective:The aim of this study was to create benchmar...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640618764710
更新日期:2018-07-01 00:00:00
abstract::The European Society of Gastrointestinal Endoscopy (ESGE) and United European Gastroenterology (UEG) have a vision to create a thriving community of endoscopy services across Europe, collaborating with each other to provide high quality, safe, accurate, patient-centered and accessible endoscopic care. Whilst the bound...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640615624631
更新日期:2016-02-01 00:00:00
abstract:Background:There is no consensus on what constitutes adequate training for needle knife precut sphincterotomy. Objective:The purpose of this study was to determine the number of procedures required before effective and safe precut sphincterotomy can be achieved. Methods:This retrospective study examined the cumulativ...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640617701808
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND AND AIM:The efficacy of clipping for preventing delayed bleeding after colorectal endoscopic resection is still controversial. To assess the efficacy of prophylactic clipping, we conducted a meta-analysis of randomized controlled trials. METHODS:We searched PubMed, the Cochrane library, and the Igaku-chuo-z...
journal_title:United European gastroenterology journal
pub_type: 杂志文章,评审
doi:10.1177/2050640616687837
更新日期:2017-10-01 00:00:00
abstract:Background:Intestinal microbiota and their metabolites (e.g. short-chain fatty acids (SCFAs)) may influence nonalcoholic fatty liver disease (NAFLD). Objective:The objective of this article is to analyze gut bacterial diversity together with fecal SCFA concentrations and immunophenotyping of peripheral blood in histol...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640618804444
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to investigate the impact of obesity on disease activity and disease outcome in patients with inflammatory bowel disease. PATIENTS AND METHODS:The impact of obesity on inflammatory bowel disease disease activity and outcome was retrospectively assessed in 3075 patients enrolled ...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640620954556
更新日期:2020-12-01 00:00:00
abstract:Background:Recent studies suggest that the prevalence of celiac disease is rising. We previously established the prevalence of celiac disease in healthy blood donors in 2002. Objective:The purpose of this study was to examine whether the prevalence of celiac disease and celiac disease autoimmunity has changed over tim...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640618818227
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Women conceiving following in vitro fertilization (IVF) likely have a variety of risk factors that predispose them to gastroesophageal reflux disease (GERD) in the future. OBJECTIVE:We aimed to investigate whether pregnancy through IVF may predispose to subsequent GERD compared with pregnancies without IVF....
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640615597836
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Patients with Crohn's disease (CD) frequently complain of cognitive difficulties such as problems with concentration and clouding of thought, yet this has scarcely been objectively defined and underlying mechanisms remain unknown. OBJECTIVE:The objective of this article is to objectively measure cognitive i...
journal_title:United European gastroenterology journal
pub_type: 杂志文章
doi:10.1177/2050640616663397
更新日期:2017-06-01 00:00:00