Vitamin D deficiency predicts severe acute pancreatitis.

Abstract:

Background:The ability to predict the severity of disease is important to reduce morbidity and mortality in patients with acute pancreatitis (AP). Vitamin D deficiency has been associated with severity in various diseases. Objective:This study was conducted to assess vitamin D as a predictor of disease severity in patients with AP. Methods:Patients with AP were prospectively enrolled at Yonsei University Wonju College of Medicine from March 2015 to September 2017. Serum vitamin D was analyzed as soon as AP was diagnosed. The level of vitamin D was classified as normal (>20 ng/ml), insufficient (>10 and ≤20 ng/ml) or deficient (≤10 ng/ml). Results:Among 242 patients with AP, the prevalence of vitamin D deficiency was 56.2%, and 28.5% of patients had vitamin D insufficiency. Serum vitamin D level was negatively correlated with severity indexes, such as the Atlanta classification, Computed Tomography Severity Index, Bedside Index for Severity of Acute Pancreatitis, and Ranson score. The prevalence of vitamin D deficiency increased with severity of AP according to the Atlanta classification. Vitamin D deficiency was the independent factor for predicting severe AP (OR 5.37, 95% CI 1.13-25.57, p = 0.015) and intensive care unit admission (OR 3.09, 95% CI 1.24-7.69, p = 0.035). Conclusion:Vitamin D deficiency is associated with increased severity of AP and is a predictor for intensive care unit admission.

authors

Huh JH,Kim JW,Lee KJ

doi

10.1177/2050640618811489

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

90-95

issue

1

eissn

2050-6406

issn

2050-6414

pii

10.1177_2050640618811489

journal_volume

7

pub_type

杂志文章
  • Pancreas-specific plasma amylase for assessment and diagnosis of chronic pancreatitis: New insights on an old topic.

    abstract:Background:Pancreatic function testing and imaging are used to inform the diagnosis of chronic pancreatitis, but most of these methods are time- and cost-consuming or lack diagnostic accuracy. Objective:We investigated the utility of pancreas-specific plasma amylase for assessment and diagnosis of chronic pancreatitis...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章,多中心研究

    doi:10.1177/2050640619846011

    authors: Olesen SS,Krarup H,Poulsen JL,Christensen JH,Sheel ARG,Sutton R,Greenhalf W,Halloran C,Drewes AM

    更新日期:2019-08-01 00:00:00

  • Estimation of the prevalence of intraductal papillary mucinous neoplasm of the pancreas in the French population through patients waiting for liver transplantation.

    abstract:BACKGROUND AND AIMS:Some studies have explored the prevalence of pancreatic cystic lesions (PCLs). Only one study based on magnetic resonance imaging (MRI) report examination focused specifically on intraductal papillary mucinous neoplasm (IPMN) in a European general population. The aim of this study was to evaluate th...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640616664842

    authors: Laurent L,Vullierme MP,Rebours V,Maire F,Hentic O,Francoz C,Durand F,Ruszniewski P,Lévy P

    更新日期:2017-06-01 00:00:00

  • Prognostic factors of hepatocellular carcinoma survival after radiofrequency ablation: A US population-based study.

    abstract:OBJECTIVE:To determine the survival outcome and prognostic factors of hepatocellular carcinoma (HCC) survival in patients who underwent radiofrequency ablation (RFA). METHODS:The Surveillance, Epidemiology and End Results (SEER) database was queried: There were 2588 HCC patients from 2004 to 2012 who underwent RFA. Th...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640616659024

    authors: El-Fattah MA,Aboelmagd M,Elhamouly M

    更新日期:2017-03-01 00:00:00

  • Italian consensus conference for colonic diverticulosis and diverticular disease.

    abstract::The statements produced by the Consensus Conference on Diverticular Disease promoted by GRIMAD (Gruppo Italiano Malattia Diverticolare, Italian Group on Diverticular Diseases) are reported. Topics such as epidemiology, risk factors, diagnosis, medical and surgical treatment of diverticular disease (DD) in patients wit...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640614547068

    authors: Cuomo R,Barbara G,Pace F,Annese V,Bassotti G,Binda GA,Casetti T,Colecchia A,Festi D,Fiocca R,Laghi A,Maconi G,Nascimbeni R,Scarpignato C,Villanacci V,Annibale B

    更新日期:2014-10-01 00:00:00

  • Suboptimal care for chronic pancreatitis patients revealed by moderate to low adherence to the United European Gastroenterology evidence-based guidelines (HaPanEU): A Netherlands nationwide analysis.

    abstract:BACKGROUND AND OBJECTIVE:The 2016, United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis (HaPanEU) provided evidence-based recommendations for the management of chronic pancreatitis and allowed for the objective evaluation of the quality of care in several doma...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640620937610

    authors: de Rijk FE,Kempeneers MA,Bruno MJ,Besselink MG,van Goor H,Boermeester MA,van Geenen EJ,van Hooft JE,van Santvoort HC,Verdonk RC,Dutch Pancreatitis Study Group.

    更新日期:2020-08-01 00:00:00

  • The effect of off-hours hospital admission on mortality and clinical outcomes for patients with upper gastrointestinal hemorrhage: A systematic review and meta-analysis of 20 cohorts.

    abstract:Objective:The objective of this article is to evaluate the relationship between off-hours hospital admission (weekends, public holidays or nighttime) and mortality for upper gastrointestinal hemorrhage (UGIH). Methods:Medline, Embase, Scopus, and the Chinese Biomedical Literature were searched through December 2016 to...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640617732651

    authors: Xia XF,Chiu PWY,Tsoi KKF,Chan FKL,Sung JJY,Lau JYW

    更新日期:2018-04-01 00:00:00

  • The microbiome in pancreatic diseases: Recent advances and future perspectives.

    abstract::The human microbiota exerts multiple physiological functions such as the regulation of metabolic and inflammatory processes. High-throughput sequencing techniques such as next-generation sequencing have become widely available in preclinical and clinical settings and have exponentially increased our knowledge about th...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640620944720

    authors: Ammer-Herrmenau C,Pfisterer N,Weingarten MF,Neesse A

    更新日期:2020-10-01 00:00:00

  • Lack of seasonal variation in the incidence of eosinophilic oesophagitis in adolescent and adult non-PPI-responsive oesophageal eosinophilia midwestern US populations.

    abstract:BACKGROUND:Eosinophilic oesophagitis (EoO) has been associated with allergic disorders as well as aeroallergens. The current literature has shown a possible association between seasonal variation, mainly in the spring, and the incidence of EoO. However, this data was based on small population studies that did not exclu...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640614525152

    authors: Frederickson NW,Bayman L,Valestin J,Redd M,Lee YJ,Soubra M,Schey R

    更新日期:2014-04-01 00:00:00

  • Development of benchmark quality criteria for assessing whole-endoscopy Barrett's esophagus biopsy cases.

    abstract:Background:Dysplasia in Barrett's esophagus (BE) biopsies is associated with low observer agreement among general pathologists. Therefore, expert review is advised. We are developing a web-based, national expert review panel for histological review of BE biopsies. Objective:The aim of this study was to create benchmar...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640618764710

    authors: van der Wel MJ,Duits LC,Klaver E,Pouw RE,Seldenrijk CA,Offerhaus G,Visser M,Ten Kate F,Tijssen JG,Bergman J,Meijer SL

    更新日期:2018-07-01 00:00:00

  • A combined bile and urine proteomic test for cholangiocarcinoma diagnosis in patients with biliary strictures of unknown origin.

    abstract:BACKGROUND:Detection of cholangiocarcinoma (CC) remains a diagnostic challenge particularly in patients with primary sclerosing cholangitis (PSC). We recently established diagnostic peptide marker models in bile and urine to detect CC. Our aim was to combine both models to reach a higher diagnostic accuracy of CC diagn...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640616687836

    authors: Voigtländer T,Metzger J,Schönemeier B,Jäger M,Mischak H,Manns MP,Lankisch TO

    更新日期:2017-08-01 00:00:00

  • Rising incidence of acute pancreatitis in Sweden: National estimates and trends between 1990 and 2013.

    abstract:BACKGROUND:Recent reports from western countries have indicated an increased incidence and a decreased mortality in acute pancreatitis. However, the incidence assessment has often been hampered by the inclusion of both first-time and recurrent episodes of acute pancreatitis. METHODS:In this retrospective cohort study,...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640620913737

    authors: Oskarsson V,Hosseini S,Discacciati A,Videhult P,Jans A,Ekbom A,Sadr-Azodi O

    更新日期:2020-05-01 00:00:00

  • Clostridium difficile fecal toxin level is associated with disease severity and prognosis.

    abstract:Background:Antibiotic-associated colitis caused by Clostridium difficile (C. difficile) is the most common cause of hospital-acquired diarrhea. The pathogenesis of C. difficile colitis is mediated by bacterial toxins. C. difficile infection (CDI) severity may be determined by the fecal level of these toxins. Objective...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640617750809

    authors: Cohen NA,Miller T,Na'aminh W,Hod K,Adler A,Cohen D,Guzner-Gur H,Santo E,Halpern Z,Carmeli Y,Maharshak N

    更新日期:2018-06-01 00:00:00

  • When to let the fellow do the procedure.

    abstract:Background and aims:In complex endoscopies, the initial attempt is often associated with the highest success and subsequent attempts to achieve the same outcome have a higher failure rate. An attending physician needs to decide how the ultimate success may become compromised by letting a fellow start the procedure. A d...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640617696401

    authors: Sonnenberg A

    更新日期:2017-11-01 00:00:00

  • Effect of prophylactic clipping in colorectal endoscopic resection: A meta-analysis of randomized controlled studies.

    abstract:BACKGROUND AND AIM:The efficacy of clipping for preventing delayed bleeding after colorectal endoscopic resection is still controversial. To assess the efficacy of prophylactic clipping, we conducted a meta-analysis of randomized controlled trials. METHODS:We searched PubMed, the Cochrane library, and the Igaku-chuo-z...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章,评审

    doi:10.1177/2050640616687837

    authors: Nishizawa T,Suzuki H,Goto O,Ogata H,Kanai T,Yahagi N

    更新日期:2017-10-01 00:00:00

  • Middle-term mortality and re-bleeding after initial diverticular bleeding: A nationwide study of 365 mostly elderly French patients.

    abstract:BACKGROUND AND AIMS:The aim of this study was to determine the mortality and re-bleeding rates, and the risk factors involved, in a cohort of patients with previous diverticular bleeding (DB). METHODS:In 2007, data on 2462 patients with lower gastrointestinal (GI) bleeding were collected prospectively at several Frenc...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640616647816

    authors: Lorenzo D,Gallois C,Lahmek P,Lesgourgues B,Champion C,Charpignon C,Faroux R,Bour B,Remy AJ,Naouri C,Picon M,Poncin E,Macaigne G,Seyrig JA,Bernardini D,Bellaïche G,Grasset D,Henrion J,Heluwaert F,Piperaud R,Bordes

    更新日期:2017-02-01 00:00:00

  • Endoscopic modalities for the diagnosis of Barrett's oesophagus.

    abstract::Barrett's oesophagus is a pre-malignant condition associated with the development of oesophageal adenocarcinoma. Currently white light endoscopy and biopsy is the mainstay diagnostic tool. Yet this approach is troubled by issues related to cumbersome biopsy sampling, biopsy sampling errors and cost. Therefore in order...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章,评审

    doi:10.1177/2050640615619281

    authors: Sharma N,Srivastava S,Kern F,Xian W,Ming T,McKeon F,Ho KY

    更新日期:2016-12-01 00:00:00

  • A multicentre prospective cohort study assessing the effectiveness of budesonide MMX® (Cortiment®MMX®) for active, mild-to-moderate ulcerative colitis.

    abstract:Background:Cortiment®MMX® (budesonide MMX®) is currently approved for the induction of remission in mild-to-moderate ulcerative colitis (UC) patients when 5-ASA treatment is not sufficient. Data in real-life settings are lacking. Methods:This was a multicentre observational prospective cohort study conducted in Europe...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章,多中心研究

    doi:10.1177/2050640619864848

    authors: Danese S,Hart A,Dignass A,Fiorino G,Louis E,Bonovas S,D'Haens G,Dotan I,Rogler G,Paridaens K,Peyrin-Biroulet L

    更新日期:2019-11-01 00:00:00

  • Effect of aspirin cessation before endoscopy in Japanese patients with low-dose-aspirin-associated gastroduodenal mucosal injury.

    abstract:BACKGROUND:The incidence of upper gastrointestinal injury by low-dose aspirin (LDA) has increased. OBJECTIVE:We aimed to clarify the risk factors and prevention strategies associated with LDA-induced gastroduodenal ulcer in Japanese patients. METHODS:A retrospective study involving 284 LDA users who underwent oesopha...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640613491254

    authors: Ito Y,Sasaki M,Noguchi S,Yamaguchi S,Okaniwa N,Tanabe A,Noda H,Yanamoto K,Tamura Y,Kondo Y,Masui R,Izawa S,Iida A,Mizuno M,Ogasawara N,Funaki Y,Kasugai K

    更新日期:2013-08-01 00:00:00

  • Deprescribing medications that may increase the risk of hepatic encephalopathy: A qualitative study of patients with cirrhosis and their doctors.

    abstract:BACKGROUND AND AIMS:Multiple medications are associated with an increased risk of incident hepatic encephalopathy. Despite this known risk, medications such as opioids, benzodiazepines, gabapentin/pregabalin, and/or proton pump inhibitors are increasingly prescribed to persons with cirrhosis. Deprescribing is a promisi...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640620975224

    authors: Williams S,Louissaint J,Nikirk S,Bajaj JS,Tapper EB

    更新日期:2020-11-23 00:00:00

  • Distinct metaplastic and inflammatory phenotypes in autoimmune and adenocarcinoma-associated chronic atrophic gastritis.

    abstract:BACKGROUND:Autoimmune gastritis (AIG) and adenocarcinoma-associated chronic atrophic gastritis (CAG) are both associated with oxyntic atrophy, but AIG patients demonstrate an increased risk of carcinoid tumors rather than the elevated risk of adenocarcinoma observed with CAG. We therefore sought to compare the characte...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640616644142

    authors: Jeong S,Choi E,Petersen CP,Roland JT,Federico A,Ippolito R,D'Armiento FP,Nardone G,Nagano O,Saya H,Romano M,Goldenring JR

    更新日期:2017-02-01 00:00:00

  • Clinical outcomes using a faecal immunochemical test for haemoglobin as a first-line test in a national programme constrained by colonoscopy capacity.

    abstract:INTRODUCTION:Because of their many advantages, faecal immunochemical tests (FIT) are superseding traditional guaiac-based faecal occult blood tests in bowel screening programmes. METHODS:A quantitative FIT was adopted for use in two evaluation National Health Service (NHS) Boards in Scotland using a cut-off faecal hae...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640613489281

    authors: Steele RJ,McDonald PJ,Digby J,Brownlee L,Strachan JA,Libby G,McClements PL,Birrell J,Carey FA,Diament RH,Balsitis M,Fraser CG

    更新日期:2013-06-01 00:00:00

  • Ruling in or out a source of gastrointestinal bleeding.

    abstract:BACKGROUND AND AIMS:The search for a source of gastrointestinal bleeding is associated with two distinct approaches of trying to rule in a specific diagnosis or rule out any potential source of bleeding. The study aim was to understand the conceptual differences underlying the two searches. METHODS:The performance of ...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640614557319

    authors: Sonnenberg A

    更新日期:2014-12-01 00:00:00

  • Colonic motility in ulcerative colitis.

    abstract:BACKGROUND:Inflammatory conditions affecting the gut may cause motility disturbances, and ulcerative colitis - one of the main disorders among the inflammatory bowel diseases - may display abnormal colonic motility. AIM:To review the abnormalities of the large bowel in ulcerative colitis, by considering the motility, ...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章,评审

    doi:10.1177/2050640614548096

    authors: Bassotti G,Antonelli E,Villanacci V,Baldoni M,Dore MP

    更新日期:2014-12-01 00:00:00

  • Endoscopic submucosal dissection of gastric superficial neoplastic lesions: a single Western center experience.

    abstract:Background:Endoscopic submucosal dissection (ESD) allows "en bloc" resection of superficial gastric lesions. Objective:The aim of this study is to report "en bloc" resection rate, procedure results, post resection features, analysis of complications, and relapses at mid-long term follow-up on an Italian center case se...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640617722901

    authors: Petruzziello L,Campanale M,Spada C,Ricci R,Hassan C,Gullo G,Costamagna G

    更新日期:2018-03-01 00:00:00

  • Sphingosine kinase 1 inhibition improves lipopolysaccharide/D-galactosamine-induced acute liver failure by inhibiting mitogen-activated protein kinases pathway.

    abstract:BACKGROUND:Sphingosine kinase 1 (SphK1)/sphingosine-1-phosphate (S1P)/sphingosine-1-phosphate receptors (S1PRs) signaling plays a key role in inflammatory responses. Lei et al. showed that SphK1 inhibition presented a hepatoprotective effect on acute liver damage via decreasing hepatic high-mobility group box 1 (HMGB1)...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640616637968

    authors: Tian T,Tian W,Yang F,Zhao R,Huang Q,Zhao Y

    更新日期:2016-10-01 00:00:00

  • Endosonography For Right-sided and Acute Upper Intestinal Misery: the EFRAIM study: A prospective, randomized, controlled, blinded study.

    abstract:BACKGROUND:Acute upper abdominal pain is a frequent symptom leading to hospital admission. OBJECTIVE:To determine whether a primary intra- and extraluminal diagnostic approach enabled by endoscopic ultrasound is as effective as a conventional diagnostic algorithm of transabdominal ultrasound followed by oesophagogastr...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640613498589

    authors: Jung A,Schlag C,Becker V,von Delius S,Lersch C,Jeliazkova P,Herner A,Bajbouj M,Schuster T,Meining A

    更新日期:2013-10-01 00:00:00

  • Use of complementary and alternative medicine and low quality of life associate with the need for psychological and psychotherapeutic interventions in inflammatory bowel disease.

    abstract:INTRODUCTION:Patients with inflammatory bowel disease suffer from various symptoms, impairing their quality of life and often affecting psychosocial issues. This may lead to the need for additional psychological care. This study investigated patients' subjective need for integrated psychosomatic support and psychothera...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640620946874

    authors: Kutschera M,Waldhör T,Gröchenig HP,Haas T,Wenzl H,Steiner P,Koch R,Feichtenschlager T,Eckhardt G,Mayer A,Kirchgatterer A,Ludwiczek O,Platzer R,Papay P,Gartner J,Fuchssteiner H,Peters PG,Reicht G,Moser G,Dejaco C,V

    更新日期:2020-07-28 00:00:00

  • Underwater endoscopic colorectal polyp resection: Feasibility in everyday clinical practice.

    abstract:Background:Endoscopic mucosal resection is well-established for resecting flat or sessile benign colon polyps. The novel underwater endoscopic mucosal resection eschews submucosal injection prior to endoscopic mucosal resection. Reports about underwater endoscopic mucosal resection were limited to small series of singl...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640617733923

    authors: Cadoni S,Liggi M,Gallittu P,Mura D,Fuccio L,Koo M,Ishaq S

    更新日期:2018-04-01 00:00:00

  • Relationships between psychological state, abuse, somatization and visceral pain sensitivity in irritable bowel syndrome.

    abstract:Background and objective:Psychological states may interfere with visceral sensitivity. Here we investigate associations between psychosocial factors and visceral sensitivity in irritable bowel syndrome (IBS). Methods:Two IBS patient cohorts (Cohort 1: n = 231, Rome II; Cohort 2: n = 141, Rome III) underwent rectal bar...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640617715851

    authors: Grinsvall C,Törnblom H,Tack J,Van Oudenhove L,Simrén M

    更新日期:2018-03-01 00:00:00

  • Effect of low-dose aspirin use on pancreatic cancer development and morphological changes on imaging in IPMN: A long-term cohort study.

    abstract:Background:Aspirin use may reduce the incidence of pancreatic cancer (PC), but no data are available regarding its chemopreventive effects on intraductal papillary mucinous neoplasm (IPMN). We aimed to determine whether low-dose aspirin (LDA) reduces PC development and morphological changes on imaging in IPMN patients....

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640617693524

    authors: Takasaki Y,Nagata N,Imbe K,Hisada Y,Sekine K,Tajima T,Yanase M,Fujimoto K,Akiyama J,Uemura N

    更新日期:2017-11-01 00:00:00