Abstract:
BACKGROUND:Reliable and safe sedation is a prerequisite for endoscopic interventions. The current standard is rather safe, yet, an objective device to measure sedation depth is missing. To date, anaesthesia monitors based on processed electroencephalogram (EEG) have not been utilised in conscious sedation. OBJECTIVE:To investigate EEG parameters to differentiate consciousness in endoscopic propofol sedation. METHODS:In total, 171 patients aged 21-83 years (ASA I-III) undergoing gastrointestinal and bronchial endoscopy were enrolled. Standard monitoring and a frontotemporal 2-channel-EEG were recorded. The state of consciousness was identified by repeated requests to squeeze the investigator's hand. RESULTS:In total, 1132 state of consciousness transitions were recorded in procedures ranging from 5 to 69 minutes. Thirty-four EEG parameters from the frequency domain, time-frequency domain and complexity measures were calculated. Area under the curve ranged from 0.51 to 0.82 with complexity and optimised frequency domain parameters yielding the best results. CONCLUSION:Prediction of the state of consciousness with processed EEG parameters is feasible, and results for sedation in endoscopic procedures are similar to those reported from general anaesthesia. These results are insufficient for a clinical application, but prediction capability may be increased with optimisation and modelling.
journal_name
United European Gastroenterol Jjournal_title
United European gastroenterology journalauthors
Garbe J,Eisenmann S,Kantelhardt JW,Duenninghaus F,Michl P,Rosendahl Jdoi
10.1177/2050640620959153subject
Has Abstractpub_date
2020-09-14 00:00:00pages
2050640620959153eissn
2050-6406issn
2050-6414pub_type
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