[Use of potentially inappropriate medication by the elderly in São Paulo, Brazil: SABE Study].

Abstract:

:Various medicines are considered unsuitable for older adults due to alterations in pharmacokinetics/pharmacodynamics, lack of therapeutic efficacy, and/or increased risk of adverse events exceeding potential benefits. The aim of this study was to determine the prevalence of potentially inappropriate medication among older adults in the city of São Paulo, Brazil. A population-based cross-sectional study was conducted in a sample of 1,254 individuals aged 60 years or older (participants in the SABE Study), representing the elderly population of the city in 2006. Potentially inappropriate medication was defined according to the Beers criteria. Prevalence of potentially inappropriate medication was 28%. Potentially inappropriate medication was associated with polypharmacy (p=0.001), two or more diseases (p=0.011), and female gender (p=0.007). Thirty-six potentially inappropriate medicines were identified, the majority of which involving prescription medications. Specific criteria are needed for the Brazilian population, in addition to awareness-raising on clinical pharmacology in older adults. Prescription protocols and software programs could assist in the process of rational prescribing in this age group.

journal_name

Cad Saude Publica

authors

Cassoni TC,Corona LP,Romano-Lieber NS,Secoli SR,Duarte YA,Lebrão ML

doi

10.1590/0102-311x00055613

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

1708-20

issue

8

eissn

0102-311X

issn

1678-4464

pii

S0102-311X2014000801708

journal_volume

30

pub_type

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