Abstract:
:Various medicines are considered unsuitable for older adults due to alterations in pharmacokinetics/pharmacodynamics, lack of therapeutic efficacy, and/or increased risk of adverse events exceeding potential benefits. The aim of this study was to determine the prevalence of potentially inappropriate medication among older adults in the city of São Paulo, Brazil. A population-based cross-sectional study was conducted in a sample of 1,254 individuals aged 60 years or older (participants in the SABE Study), representing the elderly population of the city in 2006. Potentially inappropriate medication was defined according to the Beers criteria. Prevalence of potentially inappropriate medication was 28%. Potentially inappropriate medication was associated with polypharmacy (p=0.001), two or more diseases (p=0.011), and female gender (p=0.007). Thirty-six potentially inappropriate medicines were identified, the majority of which involving prescription medications. Specific criteria are needed for the Brazilian population, in addition to awareness-raising on clinical pharmacology in older adults. Prescription protocols and software programs could assist in the process of rational prescribing in this age group.
journal_name
Cad Saude Publicajournal_title
Cadernos de saude publicaauthors
Cassoni TC,Corona LP,Romano-Lieber NS,Secoli SR,Duarte YA,Lebrão MLdoi
10.1590/0102-311x00055613subject
Has Abstractpub_date
2014-08-01 00:00:00pages
1708-20issue
8eissn
0102-311Xissn
1678-4464pii
S0102-311X2014000801708journal_volume
30pub_type
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