Abstract:
:Dry eye syndrome is a disease of the ocular surface and tear film that is prevalent in older adults. Even though the degree of visual acuity loss in dry eye patients is commonly mild-to-moderate, in the aging population, this minimal change in visual status can lead to a significant decrease in visual function and quality of life. A healthy ocular surface is maintained by appropriate tear production and tear drainage, and deficiencies in this delicate balance can lead to dryness. In the aging eye, risk factors such as polypharmacy, androgen deficiency, decreased blink rates, and oxidative stress can predispose the patient to developing dry eye that is frequently more severe, has higher economic costs, and leads to worse consequences to the well-being of the patient. Understanding why elderly patients are at higher risk for developing dry eyes can provide insights into the diagnosis and management of the growing number of older adults struggling with dry eye and minimize the burden of disease on our aging population.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Sharma A,Hindman HBdoi
10.1155/2014/781683subject
Has Abstractpub_date
2014-01-01 00:00:00pages
781683eissn
2090-004Xissn
2090-0058journal_volume
2014pub_type
杂志文章,评审abstract:Purpose:The correlations between the axial length-to-corneal radius (AL/CR) ratio and corneal astigmatism (CA) were studied by prospectively analyzing and comparing survey data from school children in the Beijing urban area from 2014 to 2015. Methods:In this longitudinal study, a total of 2,970 students were enrolled ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/4209236
更新日期:2018-08-30 00:00:00
abstract::Aim. To investigate the utility of fundus autofluorescence (FAF) and optical coherence tomography (OCT) in the evaluation of cystoid macular edema (CME) following cataract surgery. Materials and Methods. Forty eyes of 29 patients undergone phacoemulsification, with posterior chamber intraocular lens implantation surge...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/376013
更新日期:2013-01-01 00:00:00
abstract::Current intraocular pressure (IOP) measurement using air puff could be erroneous without applying proper corrections. Although noncontact tonometry is not considered to be accurate, it is still popularly used by eye clinics. It is thus necessary to extract the correct information from their results. This study propose...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/5410143
更新日期:2017-01-01 00:00:00
abstract::Purpose. To investigate the effect of cigarette smoking on the ocular tear film. Methods. Thirty healthy young male cigarette smokers (20-38 years old) and 30 healthy age matched nonsmokers were enrolled in the study. McMonnies questionnaire, slit lamp, and PRT test were used to screen the subjects. Tear samples were ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/8154315
更新日期:2016-01-01 00:00:00
abstract:Purpose:To investigate whether the risk of subsequent stroke, ischemic stroke, hemorrhagic stroke, and all-cause mortality is increased among retinal vein occlusion (RVO) patients compared to non-RVO patients. Methods:From the entire population of the Taiwan National Health Insurance Research Database (NHIRD) from 200...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/8629429
更新日期:2018-09-09 00:00:00
abstract::LASIK eye surgery has become a very common practice for myopic people, especially those in the military. Sometimes undertaken by people who need to keep a specific medical aptitude, this surgery could be performed in secret from the hierarchy and from the institute medical staff. However, even though the eyes have bee...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/762364
更新日期:2014-01-01 00:00:00
abstract::The functional visual acuity test which is the average of the visual acuities measured during a specific time frame (standard, 60 seconds) has been used recently to assess the visual function in various conditions. The availability of a shorter version of the functional visual acuity test promises to be patient friend...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/8950418
更新日期:2019-09-10 00:00:00
abstract:Background:The aim of this meta-analysis was to compare morphological and functional outcomes between vitrectomy with the inverted internal limiting membrane (ILM) flap technique and vitrectomy with internal limiting membrane peeling in highly myopic eyes with macular hole- (MH-) induced retinal detachment (MHRD). Met...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2020/2374650
更新日期:2020-08-24 00:00:00
abstract::Purpose. To evaluate the corneal higher-order aberrations (HOA), contrast sensitivity function (CSF), and light distortion (LD) in patients undergoing orthokeratology (OK). Methods. Twenty healthy subjects (mean age: 21.40 ± 8 years) with mean spherical equivalent refractive error M = -2.19 ± 0.97 D were evaluated at ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/8453462
更新日期:2016-01-01 00:00:00
abstract::The retinal degeneration 11 (rd11) mouse is a new animal model with rapid photoreceptor degeneration. The long-term efficacy of gene therapy has a direct relationship with the onset of photoreceptor degeneration or apoptosis, whereas the degeneration or apoptosis patterns of photoreceptors are still unclear in rd11 mi...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/9721362
更新日期:2017-01-01 00:00:00
abstract:Purpose:Glaucoma is the leading cause of irreversible blindness throughout the world. The pathogenesis of glaucoma is complex, and neuroprotection is a crucial aspect of therapy. High concentrations of extracellular glutamate are toxic to the optic nerve. The glutamate-aspartate transporter (GLAST) in retinal Müller ce...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/6128470
更新日期:2018-10-31 00:00:00
abstract::Purpose. To evaluate the outcome of combined vitrectomy with phacoemulsification without postoperative face-down positioning for idiopathic macular holes (MHs). Design. Retrospective, observational case series. Participants. Forty-two eyes of 42 patients with MH. Methods. We studied 42 eyes of 42 cases followed up for...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2012/571748
更新日期:2012-01-01 00:00:00
abstract:Purpose:To evaluate the difference in the repeatability of automated superficial retinal vessel density and foveal avascular zone (FAZ) metrics according to the measurement area of optical coherence tomography angiography (OCTA). Methods:A total of 127 normal eyes from 127 healthy subjects were included. Macular angio...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/5686894
更新日期:2020-04-17 00:00:00
abstract::Purpose. We evaluated the ability of novel optical coherence tomography (OCT) parameters to predict postoperative best-corrected visual acuity (BCVA) in macula-off rhegmatogenous retinal detachment (RRD) eyes. Methods. We reviewed the medical records of 56 consecutive eyes with macula-off RRD. Clinical findings were a...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/269837
更新日期:2014-01-01 00:00:00
abstract::Purpose. To evaluate the relationship between the macular ganglion cell complex (mGCC) thickness, which is the sum of the retinal nerve fiber, ganglion cell, and inner plexiform layers, measured with a spectral-domain optical coherence tomograph and the optic nerve head topography measured with a confocal scanning las...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2011/914250
更新日期:2011-01-01 00:00:00
abstract::Purpose. To investigate the thickness of the retinal nerve fiber layer (RNFL) and choroid in patients who have migraines in comparison to healthy controls. Methods. This study included 76 eyes and patients in the migraine group, 36 with aura (MWA group) and 40 without (MWoA group), and 38 eyes as control subjects. The...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/868967
更新日期:2015-01-01 00:00:00
abstract::Purpose. The aim of this study is to investigate the etiology and the clinical, microbiological, histopathological, and radiological findings of acquired dacryocystoceles. Methods. In this retrospective study, we reviewed the clinical records of 10 eyes of 8 patients with dacryocystoceles who underwent external dacryo...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/396782
更新日期:2014-01-01 00:00:00
abstract::Purpose. To evaluate the neutrophil/lymphocyte ratio (NLR) and the platelet/lymphocyte ratio(PLR) value in the development of branch retinal vein occlusion (BRVO)patients. METHODS:81 patients with BRVO and 81 age and sex-matched subjects were recruited as the control group. The BRVO diagnosis was confirmed under comp...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/6043612
更新日期:2019-10-31 00:00:00
abstract:PURPOSE:To evaluate sequential changes in choroidal thickness at the affected area in patients with acute zonal occult outer retinopathy (AZOOR). METHODS:This retrospective observational case series included 14 affected eyes and 6 unaffected fellow eyes from 10 AZOOR patients with impaired macular area. Using enhanced...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/2371032
更新日期:2017-01-01 00:00:00
abstract:Purpose:To compare the qualitative and quantitative choroidal neovascularization (CNV) changes after antivascular endothelial growth factor (anti-VEGF) therapy in treatment-naïve and treated eyes with age-related macular degeneration (AMD) using optical coherence tomography angiography (OCTA). Methods:Consecutive pati...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/3751702
更新日期:2018-02-04 00:00:00
abstract:Purpose:To evaluate contrast sensitivity (CS) changes in acute central serous chorioretinopathy (CSC). Methods:Visual acuity (VA), CS, and subretinal fluid (SRF) were evaluated monthly for 6 months. Treatment was considered at 3 months in case of persistent SRF. Results:Twelve of 20 eyes (60%) had spontaneous SRF res...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/9053932
更新日期:2017-01-01 00:00:00
abstract::The new type implantable Collamer lens with a central hole (V4c-ICL) is widely used to treat myopia. However, halos occur in some patients after surgery. The aim is to evaluate the effect of V4c-ICL implantation on vision-related daily activities. This retrospective study included 42 patients. Uncorrected visual acuit...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/5717932
更新日期:2016-01-01 00:00:00
abstract::Idiopathic full-thickness macular hole is a severe visual impairment disease. Pars plana vitrectomy remains the primary treatment option for idiopathic full-thickness macular holes, and over 90% idiopathic full-thickness macular holes are closed by vitrectomy surgery. However, the full-thickness macular hole may close...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2019/4793764
更新日期:2019-03-13 00:00:00
abstract::Objective. We aimed to assess peripheral vascular endothelial function in open-angle glaucoma (POAG) by measuring flow-mediated dilatation (FMD). Materials and Methods. The study included 20 cases with POAG (group 1, mean age 58.68 ± 13.3 years) and 30 healthy individuals (group 2, mean age 58.68 ± 13.6 years). In all...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/529082
更新日期:2014-01-01 00:00:00
abstract::Keratoconus is typically diagnosed through changes at the anterior ocular surface. However, we wished to assess if macular parameter changes might also occur in these patients. We assessed posterior changes through the use of optical coherence tomography and compared to a nonkeratoconus patient group. All subjects und...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/245953
更新日期:2015-01-01 00:00:00
abstract:Purpose:To characterize the relative contributions of intraocular pressure (IOP) and intracranial pressure (ICP) on lamina cribrosa (LC) behavior, specifically LC depth (LCD) and LC peak strain. Methods:An axially symmetric finite element model of the posterior eye was constructed with an elongated optic nerve and ret...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/3064949
更新日期:2019-03-17 00:00:00
abstract:Purpose:To compare the impact of visual field (VF) testing on intraocular pressure (IOP) change trends between healthy subjects and glaucoma patients. Methods:We recruited healthy volunteer subjects who did not have previous ocular diseases and open-angle glaucoma patients who were medically controlled well. IOP in bo...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/7936205
更新日期:2020-07-04 00:00:00
abstract::Background. The effect of angiotensin converting enzyme inhibitors (ACEi) on regression of retinopathy in type 2 diabetics is still ill defined. Methods. We compared the incidence of retinopathy regression in 90 hypertensive type 2 diabetics randomized to at least 3-year blinded ACEi with trandolapril (2 mg/day) or no...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2010/106384
更新日期:2010-01-01 00:00:00
abstract:Aims:To determine the accuracy and repeatability of new software to automatically quantify GA areas associated to age-related macular degeneration (AMD) by swept-source optical coherence tomography (SS-OCT). Settings and Design. Tertiary referral hospital in Spain. Cross-sectional and noninterventional. Methods and Mat...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/8204641
更新日期:2020-08-05 00:00:00
abstract:Purpose:The aim of this work was to describe the ultrastructure and behavior of peeled internal limiting membrane (ILM) in macular hole (MH) surgery. Methods:Seven patients with MH were included, and vitrectomy with ILM peeling was performed in all patients. The ILM inverted flap technique was used. Two other flaps of...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/1345683
更新日期:2019-05-02 00:00:00