Aging: a predisposition to dry eyes.

Abstract:

:Dry eye syndrome is a disease of the ocular surface and tear film that is prevalent in older adults. Even though the degree of visual acuity loss in dry eye patients is commonly mild-to-moderate, in the aging population, this minimal change in visual status can lead to a significant decrease in visual function and quality of life. A healthy ocular surface is maintained by appropriate tear production and tear drainage, and deficiencies in this delicate balance can lead to dryness. In the aging eye, risk factors such as polypharmacy, androgen deficiency, decreased blink rates, and oxidative stress can predispose the patient to developing dry eye that is frequently more severe, has higher economic costs, and leads to worse consequences to the well-being of the patient. Understanding why elderly patients are at higher risk for developing dry eyes can provide insights into the diagnosis and management of the growing number of older adults struggling with dry eye and minimize the burden of disease on our aging population.

journal_name

J Ophthalmol

journal_title

Journal of ophthalmology

authors

Sharma A,Hindman HB

doi

10.1155/2014/781683

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

781683

eissn

2090-004X

issn

2090-0058

journal_volume

2014

pub_type

杂志文章,评审
  • Development of Corneal Astigmatism (CA) according to Axial Length/Corneal Radius (AL/CR) Ratio in a One-Year Follow-Up of Children in Beijing, China.

    abstract:Purpose:The correlations between the axial length-to-corneal radius (AL/CR) ratio and corneal astigmatism (CA) were studied by prospectively analyzing and comparing survey data from school children in the Beijing urban area from 2014 to 2015. Methods:In this longitudinal study, a total of 2,970 students were enrolled ...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2018/4209236

    authors: Wang F,Xiao L,Meng X,Wang L,Wang D

    更新日期:2018-08-30 00:00:00

  • Evaluation of cystoid macular edema using optical coherence tomography and fundus autofluorescence after uncomplicated phacoemulsification surgery.

    abstract::Aim. To investigate the utility of fundus autofluorescence (FAF) and optical coherence tomography (OCT) in the evaluation of cystoid macular edema (CME) following cataract surgery. Materials and Methods. Forty eyes of 29 patients undergone phacoemulsification, with posterior chamber intraocular lens implantation surge...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2013/376013

    authors: Sahin M,Cingü AK,Gözüm N

    更新日期:2013-01-01 00:00:00

  • Estimation of the Corneal Young's Modulus In Vivo Based on a Fluid-Filled Spherical-Shell Model with Scheimpflug Imaging.

    abstract::Current intraocular pressure (IOP) measurement using air puff could be erroneous without applying proper corrections. Although noncontact tonometry is not considered to be accurate, it is still popularly used by eye clinics. It is thus necessary to extract the correct information from their results. This study propose...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2017/5410143

    authors: Shih PJ,Huang CJ,Huang TH,Lin HC,Yen JY,Wang IJ,Cao HJ,Shih WP,Dai CA

    更新日期:2017-01-01 00:00:00

  • Assessment of Tear Film Quality among Smokers Using Tear Ferning Patterns.

    abstract::Purpose. To investigate the effect of cigarette smoking on the ocular tear film. Methods. Thirty healthy young male cigarette smokers (20-38 years old) and 30 healthy age matched nonsmokers were enrolled in the study. McMonnies questionnaire, slit lamp, and PRT test were used to screen the subjects. Tear samples were ...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2016/8154315

    authors: Masmali AM,Al-Shehri A,Alanazi SA,Abusharaha A,Fagehi R,El-Hiti GA

    更新日期:2016-01-01 00:00:00

  • Risk of Ischemic Stroke, Hemorrhagic Stroke, and All-Cause Mortality in Retinal Vein Occlusion: A Nationwide Population-Based Cohort Study.

    abstract:Purpose:To investigate whether the risk of subsequent stroke, ischemic stroke, hemorrhagic stroke, and all-cause mortality is increased among retinal vein occlusion (RVO) patients compared to non-RVO patients. Methods:From the entire population of the Taiwan National Health Insurance Research Database (NHIRD) from 200...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2018/8629429

    authors: Chen YY,Yen YF,Lin JX,Feng SC,Wei LC,Lai YJ,Shen YC

    更新日期:2018-09-09 00:00:00

  • Chronic Electromagnetic Exposure at Occupational Safety Level Does Not Affect the Metabolic Profile nor Cornea Healing after LASIK Surgery.

    abstract::LASIK eye surgery has become a very common practice for myopic people, especially those in the military. Sometimes undertaken by people who need to keep a specific medical aptitude, this surgery could be performed in secret from the hierarchy and from the institute medical staff. However, even though the eyes have bee...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2014/762364

    authors: Crouzier D,Dabouis V,Gentilhomme E,Vignal R,Bourbon F,Fauvelle F,Debouzy JC

    更新日期:2014-01-01 00:00:00

  • Shortened Measurement Time of Functional Visual Acuity for Screening Visual Function.

    abstract::The functional visual acuity test which is the average of the visual acuities measured during a specific time frame (standard, 60 seconds) has been used recently to assess the visual function in various conditions. The availability of a shorter version of the functional visual acuity test promises to be patient friend...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2019/8950418

    authors: Hidaka Y,Masui S,Nishi Y,Ayaki M,Kaido M,Mimura M,Tsubota K,Negishi K

    更新日期:2019-09-10 00:00:00

  • Inverted Internal Limiting Membrane Flap Technique versus Internal Limiting Membrane Peeling for Vitrectomy in Highly Myopic Eyes with Macular Hole-Induced Retinal Detachment: An Updated Meta-Analysis.

    abstract:Background:The aim of this meta-analysis was to compare morphological and functional outcomes between vitrectomy with the inverted internal limiting membrane (ILM) flap technique and vitrectomy with internal limiting membrane peeling in highly myopic eyes with macular hole- (MH-) induced retinal detachment (MHRD). Met...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1155/2020/2374650

    authors: Ling L,Liu Y,Zhou B,Gao F,Hu Z,Tian M,Xing Y,Ji K,Sun T,Zhou W

    更新日期:2020-08-24 00:00:00

  • Corneal Aberrations, Contrast Sensitivity, and Light Distortion in Orthokeratology Patients: 1-Year Results.

    abstract::Purpose. To evaluate the corneal higher-order aberrations (HOA), contrast sensitivity function (CSF), and light distortion (LD) in patients undergoing orthokeratology (OK). Methods. Twenty healthy subjects (mean age: 21.40 ± 8 years) with mean spherical equivalent refractive error M = -2.19 ± 0.97 D were evaluated at ...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2016/8453462

    authors: Santolaria-Sanz E,Cerviño A,González-Méijome JM

    更新日期:2016-01-01 00:00:00

  • The Degeneration and Apoptosis Patterns of Cone Photoreceptors in rd11 Mice.

    abstract::The retinal degeneration 11 (rd11) mouse is a new animal model with rapid photoreceptor degeneration. The long-term efficacy of gene therapy has a direct relationship with the onset of photoreceptor degeneration or apoptosis, whereas the degeneration or apoptosis patterns of photoreceptors are still unclear in rd11 mi...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2017/9721362

    authors: Zhang H,Li X,Dai X,Han J,Zhang Y,Qi Y,He Y,Liu Y,Chang B,Pang JJ

    更新日期:2017-01-01 00:00:00

  • Cyanin Chloride Inhibits Hyperbaric Pressure-Induced Decrease of Intracellular Glutamate-Aspartate Transporter in Rat Retinal Müller Cells.

    abstract:Purpose:Glaucoma is the leading cause of irreversible blindness throughout the world. The pathogenesis of glaucoma is complex, and neuroprotection is a crucial aspect of therapy. High concentrations of extracellular glutamate are toxic to the optic nerve. The glutamate-aspartate transporter (GLAST) in retinal Müller ce...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2018/6128470

    authors: Chen X,Wang Y,Han F,Ke M

    更新日期:2018-10-31 00:00:00

  • Combined Idiopathic Macular Hole Vitrectomy with Phacoemulsification without Face-Down Positioning.

    abstract::Purpose. To evaluate the outcome of combined vitrectomy with phacoemulsification without postoperative face-down positioning for idiopathic macular holes (MHs). Design. Retrospective, observational case series. Participants. Forty-two eyes of 42 patients with MH. Methods. We studied 42 eyes of 42 cases followed up for...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2012/571748

    authors: Yagi F,Takagi S,Tomita G

    更新日期:2012-01-01 00:00:00

  • The Difference in Repeatability of Automated Superficial Retinal Vessel Density according to the Measurement Area Using OCT Angiography.

    abstract:Purpose:To evaluate the difference in the repeatability of automated superficial retinal vessel density and foveal avascular zone (FAZ) metrics according to the measurement area of optical coherence tomography angiography (OCTA). Methods:A total of 127 normal eyes from 127 healthy subjects were included. Macular angio...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2020/5686894

    authors: Lim HB,Kang TS,Won YK,Kim JY

    更新日期:2020-04-17 00:00:00

  • Predicting visual outcomes for macula-off rhegmatogenous retinal detachment with optical coherence tomography.

    abstract::Purpose. We evaluated the ability of novel optical coherence tomography (OCT) parameters to predict postoperative best-corrected visual acuity (BCVA) in macula-off rhegmatogenous retinal detachment (RRD) eyes. Methods. We reviewed the medical records of 56 consecutive eyes with macula-off RRD. Clinical findings were a...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2014/269837

    authors: Suzuki N,Kunikata H,Aizawa N,Abe T,Nakazawa T

    更新日期:2014-01-01 00:00:00

  • Macular retinal ganglion cell complex thickness and its relationship to the optic nerve head topography in glaucomatous eyes with hemifield defects.

    abstract::Purpose. To evaluate the relationship between the macular ganglion cell complex (mGCC) thickness, which is the sum of the retinal nerve fiber, ganglion cell, and inner plexiform layers, measured with a spectral-domain optical coherence tomograph and the optic nerve head topography measured with a confocal scanning las...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2011/914250

    authors: Takagi ST,Kita Y,Takeyama A,Tomita G

    更新日期:2011-01-01 00:00:00

  • The impact of migraine on posterior ocular structures.

    abstract::Purpose. To investigate the thickness of the retinal nerve fiber layer (RNFL) and choroid in patients who have migraines in comparison to healthy controls. Methods. This study included 76 eyes and patients in the migraine group, 36 with aura (MWA group) and 40 without (MWoA group), and 38 eyes as control subjects. The...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2015/868967

    authors: Demircan S,Ataş M,Arık Yüksel S,Ulusoy MD,Yuvacı İ,Arifoğlu HB,Başkan B,Zararsız G

    更新日期:2015-01-01 00:00:00

  • Clinical, radiological, microbiological, and histopathological aspects of acquired dacryocystoceles.

    abstract::Purpose. The aim of this study is to investigate the etiology and the clinical, microbiological, histopathological, and radiological findings of acquired dacryocystoceles. Methods. In this retrospective study, we reviewed the clinical records of 10 eyes of 8 patients with dacryocystoceles who underwent external dacryo...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2014/396782

    authors: Sendul SY,Cinar S,Cağatay HH,Demir M,Dirim B,Guven D

    更新日期:2014-01-01 00:00:00

  • Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio in Branch Retinal Vein Occlusion.

    abstract::Purpose. To evaluate the neutrophil/lymphocyte ratio (NLR) and the platelet/lymphocyte ratio(PLR) value in the development of branch retinal vein occlusion (BRVO)patients. METHODS:81 patients with BRVO and 81 age and sex-matched subjects were recruited as the control group. The BRVO diagnosis was confirmed under comp...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2019/6043612

    authors: Zhu DD,Liu X

    更新日期:2019-10-31 00:00:00

  • Relationship between Choroidal Thickness and Visual Field Impairment in Acute Zonal Occult Outer Retinopathy.

    abstract:PURPOSE:To evaluate sequential changes in choroidal thickness at the affected area in patients with acute zonal occult outer retinopathy (AZOOR). METHODS:This retrospective observational case series included 14 affected eyes and 6 unaffected fellow eyes from 10 AZOOR patients with impaired macular area. Using enhanced...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2017/2371032

    authors: Hashimoto Y,Saito W,Saito M,Hasegawa Y,Takita A,Mori S,Noda K,Ishida S

    更新日期:2017-01-01 00:00:00

  • Optical Coherence Tomography Angiography to Distinguish Changes of Choroidal Neovascularization after Anti-VEGF Therapy: Monthly Loading Dose versus Pro Re Nata Regimen.

    abstract:Purpose:To compare the qualitative and quantitative choroidal neovascularization (CNV) changes after antivascular endothelial growth factor (anti-VEGF) therapy in treatment-naïve and treated eyes with age-related macular degeneration (AMD) using optical coherence tomography angiography (OCTA). Methods:Consecutive pati...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2018/3751702

    authors: Miere A,Oubraham H,Amoroso F,Butori P,Astroz P,Semoun O,Bruyere E,Pedinielli A,Addou-Regnard M,Jung C,Cohen SY,Souied EH

    更新日期:2018-02-04 00:00:00

  • Pattern of Contrast Sensitivity Changes in Acute Central Serous Chorioretinopathy.

    abstract:Purpose:To evaluate contrast sensitivity (CS) changes in acute central serous chorioretinopathy (CSC). Methods:Visual acuity (VA), CS, and subretinal fluid (SRF) were evaluated monthly for 6 months. Treatment was considered at 3 months in case of persistent SRF. Results:Twelve of 20 eyes (60%) had spontaneous SRF res...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2017/9053932

    authors: Lourthai P,Bhurayanontachai P

    更新日期:2017-01-01 00:00:00

  • Effects of V4c-ICL Implantation on Myopic Patients' Vision-Related Daily Activities.

    abstract::The new type implantable Collamer lens with a central hole (V4c-ICL) is widely used to treat myopia. However, halos occur in some patients after surgery. The aim is to evaluate the effect of V4c-ICL implantation on vision-related daily activities. This retrospective study included 42 patients. Uncorrected visual acuit...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2016/5717932

    authors: Liu T,Linghu S,Pan L,Shi R

    更新日期:2016-01-01 00:00:00

  • Characteristics and Risk Factors for Spontaneous Closure of Idiopathic Full-Thickness Macular Hole.

    abstract::Idiopathic full-thickness macular hole is a severe visual impairment disease. Pars plana vitrectomy remains the primary treatment option for idiopathic full-thickness macular holes, and over 90% idiopathic full-thickness macular holes are closed by vitrectomy surgery. However, the full-thickness macular hole may close...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1155/2019/4793764

    authors: Liang X,Liu W

    更新日期:2019-03-13 00:00:00

  • Systemic endothelial function in primary open-angle glaucoma.

    abstract::Objective. We aimed to assess peripheral vascular endothelial function in open-angle glaucoma (POAG) by measuring flow-mediated dilatation (FMD). Materials and Methods. The study included 20 cases with POAG (group 1, mean age 58.68 ± 13.3 years) and 30 healthy individuals (group 2, mean age 58.68 ± 13.6 years). In all...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2014/529082

    authors: Atas M,Arifoglu HB,Hashas AS,Sarli B,Demircan S,Ozkose A,Goktas A

    更新日期:2014-01-01 00:00:00

  • Assessment of Macular Parameter Changes in Patients with Keratoconus Using Optical Coherence Tomography.

    abstract::Keratoconus is typically diagnosed through changes at the anterior ocular surface. However, we wished to assess if macular parameter changes might also occur in these patients. We assessed posterior changes through the use of optical coherence tomography and compared to a nonkeratoconus patient group. All subjects und...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2015/245953

    authors: Sahebjada S,Amirul Islam FM,Wickremasinghe S,Daniell M,Baird PN

    更新日期:2015-01-01 00:00:00

  • Relative Contributions of Intracranial Pressure and Intraocular Pressure on Lamina Cribrosa Behavior.

    abstract:Purpose:To characterize the relative contributions of intraocular pressure (IOP) and intracranial pressure (ICP) on lamina cribrosa (LC) behavior, specifically LC depth (LCD) and LC peak strain. Methods:An axially symmetric finite element model of the posterior eye was constructed with an elongated optic nerve and ret...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2019/3064949

    authors: Tong J,Ghate D,Kedar S,Gu L

    更新日期:2019-03-17 00:00:00

  • Impact of Visual Field Testing on Intraocular Pressure Change Trends in Healthy People and Glaucoma Patients.

    abstract:Purpose:To compare the impact of visual field (VF) testing on intraocular pressure (IOP) change trends between healthy subjects and glaucoma patients. Methods:We recruited healthy volunteer subjects who did not have previous ocular diseases and open-angle glaucoma patients who were medically controlled well. IOP in bo...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2020/7936205

    authors: Li M,Zheng B,Wang Q,Sun X

    更新日期:2020-07-04 00:00:00

  • Effect of trandolapril on regression of retinopathy in hypertensive patients with type 2 diabetes: a prespecified analysis of the benedict trial.

    abstract::Background. The effect of angiotensin converting enzyme inhibitors (ACEi) on regression of retinopathy in type 2 diabetics is still ill defined. Methods. We compared the incidence of retinopathy regression in 90 hypertensive type 2 diabetics randomized to at least 3-year blinded ACEi with trandolapril (2 mg/day) or no...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2010/106384

    authors: Ruggenenti P,Iliev I,Filipponi M,Tadini S,Perna A,Ganeva M,Ene-Iordache B,Cravedi P,Trevisan R,Bossi A,Remuzzi G

    更新日期:2010-01-01 00:00:00

  • Automatic Quantification Software for Geographic Atrophy Associated with Age-Related Macular Degeneration: A Validation Study.

    abstract:Aims:To determine the accuracy and repeatability of new software to automatically quantify GA areas associated to age-related macular degeneration (AMD) by swept-source optical coherence tomography (SS-OCT). Settings and Design. Tertiary referral hospital in Spain. Cross-sectional and noninterventional. Methods and Mat...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2020/8204641

    authors: Ruiz-Moreno JM,Ruiz-Medrano J,Lugo F,Sirvent B,Flores-Moreno I

    更新日期:2020-08-05 00:00:00

  • Morphology of Peeled Internal Limiting Membrane in Macular Hole Surgery.

    abstract:Purpose:The aim of this work was to describe the ultrastructure and behavior of peeled internal limiting membrane (ILM) in macular hole (MH) surgery. Methods:Seven patients with MH were included, and vitrectomy with ILM peeling was performed in all patients. The ILM inverted flap technique was used. Two other flaps of...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2019/1345683

    authors: Faria MY,Sousa DC,Almeida BC,Pinto AL,Ferreira NP

    更新日期:2019-05-02 00:00:00