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The disease formerly known as rheumatoid arthritis.

Abstract：

:Rheumatoid arthritis is a complex disease where predetermined and stochastic factors conspire to confer disease susceptibility. In light of the diverse responses to targeted therapies, rheumatoid arthritis might represent a final common clinical phenotype that reflects many pathogenic pathways. Therefore, it might be appropriate to begin thinking about rheumatoid arthritis as a syndrome rather than a disease. Use of genetics, epigenetics, microbiomics,and other unbiased technologies will probably permit stratification of patients based on mechanisms of disease rather than by clinical phenotype.

journal_name

Arthritis Res Ther

journal_title

Arthritis research & therapy

authors

Firestein GS

doi

10.1186/ar4593

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

114

issue

3

eissn

1478-6354

issn

1478-6362

pii

ar4593

journal_volume

16

pub_type

杂志文章

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