Measurement of gastric functions during digestion of ordinary solid meals in man.

abstract：BACKGROUND & AIMS:The absence of grade A supporting evidence for surveillance colonoscopy in patients with ulcerative colitis (UC) has led to controversy regarding its benefit, yet it is routinely recommended in practice guidelines. Limited data are available on rates of colonoscopy surveillance and factors associated ...

journal_title：Gastroenterology

authors： Velayos FS,Liu L,Lewis JD,Allison JE,Flowers N,Hutfless S,Abramson O,Perry GS,Herrinton LJ

更新日期：2010-11-01 00:00:00

abstract：:From 1979 to 1984, we followed the cases of 3 men (aged 13, 31, and 75 yr) and 2 women (aged 38 and 45 yr who had never used oral contraceptives) suffering from liver adenomatosis, an uncommon lesion consisting of numerous benign adenomas in an otherwise normal hepatic parenchyma. During the same period, we observed 2...

journal_title：Gastroenterology

authors： Flejou JF,Barge J,Menu Y,Degott C,Bismuth H,Potet F,Benhamou JP

更新日期：1985-11-01 00:00:00

abstract：:A possible role of insulinlike growth factor I (IGF-I) and IGF-I receptors in the proliferation of human colon cancer has, to the best of the authors' knowledge, not been examined as yet. To determine a role of IGF-I in colon cancer, several human colon cancer cell lines and colon cancers were screened for specific bi...

journal_title：Gastroenterology

authors： Guo YS,Narayan S,Yallampalli C,Singh P

更新日期：1992-04-01 00:00:00

abstract：:In some patients with hiatus hernia, vomiting may propel a plug of redundant gastric mucosa into the distal esophagus, where it becomes incarcerated and engorged. Significant bleeding may result. Reduction of the hernia controls the hemorrhage. Endoscopy after the acute episode may demonstrate a gastric mucosal lesion...

journal_title：Gastroenterology

authors： Laforet EG

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND & AIMS:The basic mechanisms of food allergies are still unknown. The aims of this study were to investigate whether endothelins (ETs) in the intestinal mucosa are involved in the pathogenesis of intestinal anaphylaxis. METHODS:Sprague-Dawley rats were sensitized to chicken egg albumin (EA) by intraperitonea...

journal_title：Gastroenterology

authors： Shigematsu T,Miura S,Hirokawa M,Hokari R,Higuchi H,Tsuzuki Y,Kimura H,Nakatsumi RC,Serizawa H,Saito H,Ishii H

更新日期：1998-08-01 00:00:00

abstract：:Cholangiocarcinoma occurs in approximately 10% of patients with primary sclerosing cholangitis. Usually, liver failure, rapidly progressing jaundice, and an increase in alkaline phosphatase levels are suggestive diagnostic features. We report two cases of patients with primary sclerosing cholangitis who developed chol...

journal_title：Gastroenterology

authors： Martins EB,Fleming KA,Garrido MC,Hine KR,Chapman RW

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND & AIMS:The mechanism regulating cholecystokinin (CCK) secretion during prolonged diversion of bile pancreatic juice (BPJ) is unknown. We examined the hypothesis that the decrease of plasma CCK levels after prolonged diversion of BPJ is mediated by an increase in plasma somatostatin levels evoked by hyperchol...

journal_title：Gastroenterology

authors： Li Y,Hao Y,Owyang C

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Actin is a key contractile protein associated with the normal differentiation and function of gastrointestinal smooth muscle cells. Distinct changes in gastrointestinal smooth muscle cell morphology and function have been reported for the aganglionic rectum and megacolon of the adult lethal spotted mouse. Th...

journal_title：Gastroenterology

authors： Liddell RA,Mooers SU,Siegman MJ,McHugh KM

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND & AIMS:Math1 (Atoh1) is a basic helix-loop-helix transcription factor important for intestinal secretory cell differentiation. We hypothesized that Math1 is important in cell fate commitment, and therefore mediates proliferative homeostasis and the adaptive response following intestinal resection in the adul...

journal_title：Gastroenterology

authors： Shroyer NF,Helmrath MA,Wang VY,Antalffy B,Henning SJ,Zoghbi HY

更新日期：2007-06-01 00:00:00

abstract：:Reduction in caloric intake was associated with a greater absolute rise in the serum bilirubin concentration in patients with Gilbert's syndrome and partial hepatic bilirubin uridine diphosphate glucuronyltransferase (UDPG-T) dysfunction compared to patients with hemolytic unconjugated hyperbilirubinemia and normal su...

journal_title：Gastroenterology

authors： Felsher BF,Carpio NM

更新日期：1975-07-01 00:00:00

abstract：BACKGROUND & AIMS:Pancreatic ductal adenocarcinoma (PDAC) is characterized by a fibroblast-rich desmoplastic stroma. Cancer-associated fibroblasts (CAFs) have been shown to display a high degree of interconvertible states including quiescent, inflammatory, and myofibroblastic phenotypes; however, the mechanisms by whic...

journal_title：Gastroenterology

authors： Feldmann K,Maurer C,Peschke K,Teller S,Schuck K,Steiger K,Engleitner T,Öllinger R,Nomura A,Wirges N,Papargyriou A,Jahan Sarker RS,Ranjan RA,Dantes Z,Weichert W,Rustgi AK,Schmid RM,Rad R,Schneider G,Saur D,Reichert

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Several studies suggest that statins prevent some cancers, with one study finding a 47% reduction in colorectal cancer risk after >or=5 years of regular use. METHODS:A nested case-control study was conducted within 454 general practices in the United Kingdom using the QRESEARCH database. Cases with...

journal_title：Gastroenterology

authors： Vinogradova Y,Hippisley-Cox J,Coupland C,Logan RF

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND & AIMS:Progressive familial intrahepatic cholestasis can be caused by mutations in ABCB4 or ATP8B1; each encodes a protein that translocates phospholipids, but in opposite directions. ABCB4 flops phosphatidylcholine from the inner to the outer leaflet, where it is extracted by bile salts. ATP8B1, in complex ...

journal_title：Gastroenterology

authors： Groen A,Romero MR,Kunne C,Hoosdally SJ,Dixon PH,Wooding C,Williamson C,Seppen J,Van den Oever K,Mok KS,Paulusma CC,Linton KJ,Oude Elferink RP

更新日期：2011-11-01 00:00:00

abstract：UNLABELLED:We investigated a patient (W.B.) with chronic symptomatic Giardiasis despite seven separate courses of either quinacrine or metronidazole who was cured by combined quinacrine and metronidazole. After isolating Giardia lamblia from W.B., we cultured the trophozoites to make the following observations. In vitr...

journal_title：Gastroenterology

authors： Smith PD,Gillin FD,Spira WM,Nash TE

更新日期：1982-10-01 00:00:00

abstract：:Spinal cord stimulation is an increasingly popular form of pain treatment. An electrode positioned on the dorsal aspect of the spinal cord at the level of the nerve roots from the painful area stimulates the spinal cord. Current from the electrode is supplied by a pulse generator in the lower anterior abdominal wall. ...

journal_title：Gastroenterology

authors： Kemler MA,Barendse GA,Van Kleef M

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND & AIMS:Dysbiosis of the intestinal microbiota has been associated with development of allergies in infants. However, it is not clear what microbes might contribute to this process. We investigated what microbe(s) might be involved in analyses of infant twins and mice. METHODS:We studied fecal specimens pros...

journal_title：Gastroenterology

authors： Chua HH,Chou HC,Tung YL,Chiang BL,Liao CC,Liu HH,Ni YH

更新日期：2018-01-01 00:00:00

abstract：:Elevated levels of serum albumin have been noted in patients on chronic methadone maintenance and in heroin addicts. This observation was investigated in rabbits maintained on daily methadone 4 mg per kg of body weight after a period of 3 months on increasing dosage to assure drug tolerance. Albumin distribution and m...

journal_title：Gastroenterology

authors： Rothschild MA,Kreek MJ,Oratz M,Schreiber SS,Mongelli JG

更新日期：1976-08-01 00:00:00

abstract：BACKGROUND & AIMS:Confocal laser endomicroscopy (CLE) is a technique that permits real-time detection and quantification of changes in intestinal tissues and cells, including increases in intraepithelial lymphocytes and fluid extravasation through epithelial leaks. Using CLE analysis of patients with irritable bowel sy...

journal_title：Gastroenterology

authors： Fritscher-Ravens A,Pflaum T,Mösinger M,Ruchay Z,Röcken C,Milla PJ,Das M,Böttner M,Wedel T,Schuppan D

更新日期：2019-07-01 00:00:00

abstract：:We describe a novel "silvering" method to determine the surface area of nonspherical objects and have applied this method to human cholesterol gallstones. A standard curve is first constructed, using data obtained from the dissolution rates of silver-coated plastic spheres of known dimensions in unstirred thiosulfate-...

journal_title：Gastroenterology

authors： Park YH,Igimi H,Carey MC

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND & AIMS:Patients with chronic hepatitis B virus (HBV) infection have a high risk for developing hepatocellular carcinoma (HCC). Patients with lower levels of hepatitis B surface antigen (HBsAg) have higher chances of losing HBsAg than those with high levels. However, little is known about whether higher level...

journal_title：Gastroenterology

authors： Tseng TC,Liu CJ,Yang HC,Su TH,Wang CC,Chen CL,Kuo SF,Liu CH,Chen PJ,Chen DS,Kao JH

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND & AIMS:Foxl1(+) hepatic progenitor cells (HPCs) differentiate into cholangiocytes and hepatocytes after liver injury. We investigated the requirement for Foxl1(+) HPCs in recovery from liver injury in mice. METHODS:We developed mice in which we could trace and delete Foxl1-expressing HPCs and their descenda...

journal_title：Gastroenterology

authors： Shin S,Upadhyay N,Greenbaum LE,Kaestner KH

更新日期：2015-01-01 00:00:00

abstract：:The transport of folic acid was investigated in organ-cultured endoscopic biopsy specimens of intestinal mucosa from normal subjects. In the proximal small intestine at pH 5.5 and 6.5, [3H]folic acid accumulated to concentrations 2.64- and 2.17-fold higher than those of the medium, respectively, but at pH 7.5 the conc...

journal_title：Gastroenterology

authors： Zimmerman J

更新日期：1990-10-01 00:00:00

abstract：:Somatostatin receptor frequency was evaluated in 12 human exocrine pancreatic carcinomas taken after surgery. The tumors were analyzed by receptor autoradiography on tissue sections and by in vitro binding techniques on tumor homogenates. None of the tested human pancreatic carcinomas was shown to possess specific som...

journal_title：Gastroenterology

authors： Reubi JC,Horisberger U,Essed CE,Jeekel J,Klijn JG,Lamberts SW

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND & AIMS:Few studies, even those with cohort designs, test the mediating effects of infant gut microbes and metabolites on the onset of disease. We undertook such a study. METHODS:Using structural equation modeling path analysis, we tested directional relationships between first pregnancy, birth mode, prolong...

journal_title：Gastroenterology

authors： Vu K,Lou W,Tun HM,Konya TB,Morales-Lizcano N,Chari RS,Field CJ,Guttman DS,Mandal R,Wishart DS,Azad MB,Becker AB,Mandhane PJ,Moraes TJ,Lefebvre DL,Sears MR,Turvey SE,Subbarao P,Scott JA,Kozyrskyj AL

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The mammalian intestinal epithelium self-renews rapidly and homeostasis is preserved via tightly controlled mechanisms. Long noncoding RNAs transcribed from ultraconserved regions (T-UCRs) control different cell functions, but little is known about their role in maintaining the integrity of the inte...

journal_title：Gastroenterology

authors： Xiao L,Wu J,Wang JY,Chung HK,Kalakonda S,Rao JN,Gorospe M,Wang JY

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND/AIMS:Ursodeoxycholic acid (UDCA) and colchicine have beneficial effects in primary biliary cirrhosis (PBC). The efficacy of colchicine and UDCA in PBC was compared in a 2-year placebo-controlled study (n = 90). METHODS:Clinical events, laboratory test results, and liver histology were recorded at the beginn...

journal_title：Gastroenterology

authors： Vuoristo M,Färkkilä M,Karvonen AL,Leino R,Lehtola J,Mäkinen J,Mattila J,Friman C,Seppälä K,Tuominen J

更新日期：1995-05-01 00:00:00

abstract：:To define a potential role for the angiotensin system in Crohn's colitis, the colonic mucosal levels of angiotensin I and II were measured in endoscopic biopsy samples from patients with active Crohn's colitis (n = 20), ulcerative colitis (n = 13), other forms of colitis (n = 3), and normal controls (n = 17). Colonic ...

journal_title：Gastroenterology

authors： Jaszewski R,Tolia V,Ehrinpreis MN,Bodzin JH,Peleman RR,Korlipara R,Weinstock JV

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND & AIMS:Nuclear factor kappaB (NF-kappaB) is the master regulator of tumor necrosis factor (TNF) susceptibility. Although mitochondrial glutathione (mGSH) depletion was shown to sensitize hepatocytes to TNF despite NF-kappaB activation, the mechanisms involved, particularly the role of Bax oligomerization and...

journal_title：Gastroenterology

authors： Marí M,Colell A,Morales A,Caballero F,Moles A,Fernández A,Terrones O,Basañez G,Antonsson B,García-Ruiz C,Fernández-Checa JC

更新日期：2008-05-01 00:00:00

abstract：:Gastrointestinal symptoms occur in a large number of patients with food allergies. Immediate hypersensitivity mechanisms may give rise to the nausea, vomiting, abdominal pain, and diarrhea experienced by these patients. However, there are limited human data about the pathophysiological basis for these symptoms. Most o...

journal_title：Gastroenterology

authors： Crowe SE,Perdue MH

更新日期：1992-09-01 00:00:00

abstract：:There is increasing evidence that ingested diet-borne components are involved in the pathogenesis of disorders such as inflammatory bowel diseases, atherosclerosis, and type 2 diabetes. Nutrients can have short- and long-term effects in shaping the composition of the microbiota. Western diets (enriched in fat, phospha...

journal_title：Gastroenterology

authors： Tilg H,Moschen AR

更新日期：2015-05-01 00:00:00