Generalizability of established prostate cancer risk variants in men of African ancestry.

abstract：:Marfe, G., Pucci, B., De Martino, L., Fiorito, F., Di Stefano, C., Indelicato, M., Aventaggiato, M., Russo, M. A. and Tafani, M. (2009), Heat-shock pretreatment inhibits sorbitol-induced apoptosis in K562, U937 and HeLa cells. Int. J. Cancer, 125: 2077-2085. doi: 10.1002/ijc.24572 The above article, published online o...

journal_title：International journal of cancer

authors：

更新日期：2019-08-15 00:00:00

abstract：:Like the majority of tumor cells, ovarian cancer cell growth is critically dependent on their neovascularization. Adhesion molecules and cellular events that lead to ovarian tumor cell interactions with endothelial extracellular matrix surrounding the vasculature are poorly identified. To understand the role of alphav...

journal_title：International journal of cancer

authors： Carreiras F,Thiébot B,Leroy-Dudal J,Maubant S,Breton MF,Darbeida H

更新日期：2002-06-20 00:00:00

abstract：:The secretion of antibody by hybridoma cells allows the growth of individual cells to be measured by a hemolytic plaque assay. Similarly, plaque reduction assays were sensitive indicators of tumor immunity. A series of strains of hybridoma have been isolated from an original isolate which is sensitive to cytotoxic T c...

journal_title：International journal of cancer

authors： Ezaki T,Marbrook J

更新日期：1985-01-15 00:00:00

abstract：:In addition to antiviral effects, Type I interferons (IFN) have potent antiproliferative and immunomodulatory activities. Because of these properties IFNs have been evaluated as therapeutics for the treatment of a number of human diseases, including cancer. Currently, IFNs have been shown to be efficacious for the tre...

journal_title：International journal of cancer

authors： Wagner TC,Velichko S,Chesney SK,Biroc S,Harde D,Vogel D,Croze E

更新日期：2004-08-10 00:00:00

abstract：:Altered DNA methylation is often seen in malignant cells, potentially contributing to carcinogenesis by suppressing gene expression. We hypothesized that heritable methylation potential might be a risk factor for breast cancer and evaluated possible association with breast cancer for single nucleotide polymorphisms (S...

journal_title：International journal of cancer

authors： Harlid S,Ivarsson MI,Butt S,Hussain S,Grzybowska E,Eyfjörd JE,Lenner P,Försti A,Hemminki K,Manjer J,Dillner J,Carlson J

更新日期：2011-10-01 00:00:00

abstract：:Chimeric bcr/abl fusion proteins are thought to be the molecular 'pathogen' of chronic myelogenous leukaemia (CML). Expression levels of the respective fusion RNAs reflect disease progression as well as remission upon therapeutic intervention in CML patients. However, there is no quick and reliable method that would a...

journal_title：International journal of cancer

authors： Kreuzer KA,Lass U,Nagel S,Ellerbrok H,Pauli G,Pawlaczyk-Peter B,Siegert W,Huhn D,Schmidt CA

更新日期：2000-06-01 00:00:00

abstract：:Oxidative stress plays a role in the regulation of cancer cell metastasis which involves cell invasion and adhesion that could be supported by ADAM proteins through the activities of their metalloprotease and disintegrin domains. We hypothesized that oxidative stress could act through the induction of ADAM9 protein in...

journal_title：International journal of cancer

authors： Mongaret C,Alexandre J,Thomas-Schoemann A,Bermudez E,Chéreau C,Nicco C,Goldwasser F,Weill B,Batteux F,Lemare F

更新日期：2011-08-15 00:00:00

abstract：:3H-HSV-2 DNA has been hybridized in situ to frozen sectioned tissue from human cervical biopsies. RNA complementary to the virus-specific probe was detected in cells undergoing pre-malignant changes, but not in the cells of the fully developed squamous-cell cancer. ...

journal_title：International journal of cancer

authors： McDougall JK,Galloway DA,Fenoglio CM

更新日期：1980-01-15 00:00:00

abstract：:This report describes the appearance of ectopic chromosome around centrosome (ECAC) in metaphase cell nuclei of high-risk HPV-associated cervical neoplasms. ECAC are clearly visible on HE-stained sections as a tiny (approx. 0.7 micro), round, dark structure or an aggregate of filamentous chromosome, often symmetrical ...

journal_title：International journal of cancer

authors： Furuta R,Hirai Y,Katase K,Tate S,Kawaguchi T,Akiyama F,Kato Y,Kumada K,Iwasaka T,Yaegashi N,Kanazawa K,Yoshikawa H,Kitagawa T

更新日期：2003-08-20 00:00:00

abstract：:Interferon-beta (IFN-beta) has been used as an antitumor drug against human glioma, melanoma and medulloblastoma since the 1980s. Recently, we developed a new gene therapy using the IFN-beta gene against malignant gliomas and then began clinical trials in 2000. Since stimulation of immune system was one mechanism of a...

journal_title：International journal of cancer

authors： Saito R,Mizuno M,Nakahara N,Tsuno T,Kumabe T,Yoshimoto T,Yoshida J

更新日期：2004-09-20 00:00:00

abstract：:The expression of the recently described rap genes, closely related in the effector region to the ras proto-oncogenes, was examined by Northern blot analysis in 41 primary human tumors. The structural and in vitro biological properties of the rap gene products suggest their possible antagonistic action in the same eff...

journal_title：International journal of cancer

authors： Culine S,Olofsson B,Gosselin S,Honore N,Tavitian A

更新日期：1989-12-15 00:00:00

abstract：:Use of herbal preparations containing Aristolochia species has led to progressive nephropathy and urothelial cancer in humans. Analysis of DNA adducts formed in human target tissues and studies in animal models have pointed out a major role of the secondary plant metabolites, aristolochic acids, in these effects. Only...

journal_title：International journal of cancer

authors： Meinl W,Pabel U,Osterloh-Quiroz M,Hengstler JG,Glatt H

更新日期：2006-03-01 00:00:00

abstract：:Human papillomavirus (HPV) genomes usually persist as episomal molecules in HPV associated preneoplastic lesions whereas they are frequently integrated into the host cell genome in HPV-related cancers cells. This suggests that malignant conversion of HPV-infected epithelia is linked to recombination of cellular and vi...

journal_title：International journal of cancer

authors： Luft F,Klaes R,Nees M,Dürst M,Heilmann V,Melsheimer P,von Knebel Doeberitz M

更新日期：2001-04-01 00:00:00

abstract：:Molecular genetic mechanisms involved in the progression of prostate cancer are not well understood due to extensive tumor heterogeneity and lack of suitable models. New methods such as fluorescence in-situ hybridization (FISH), comparative genomic hybridization (CGH) and microsatellite analysis have documented losses...

journal_title：International journal of cancer

authors： Karan D,Lin MF,Johansson SL,Batra SK

更新日期：2003-01-20 00:00:00

abstract：:We aimed to identify risk factors for Kaposi's sarcoma (KS) among HIV-positive patients and behaviors associated with human Herpesvirus 8 (HHV-8) infection, as well as to assess KS incidence and mortality rates longitudinally. To fulfill the first objective, a European case-control study was designed in the early 1990...

journal_title：International journal of cancer

authors： Martró E,Esteve A,Schulz TF,Sheldon J,Gambús G,Muñoz R,Whitby D,Casabona J,Euro-Shaks study group.

更新日期：2007-03-01 00:00:00

abstract：:Tumor infiltrating T cells are a predictor of patient outcome in patients with colorectal cancer (CRC). However, many T cell populations have been associated with both poor and positive patient prognoses, indicating a need to further understand the role of different T cell subsets in CRC. In this study, the T cell inf...

journal_title：International journal of cancer

authors： Taylor ES,McCall JL,Shen S,Girardin A,Munro FM,Black MA,Ward-Hartstonge KA,Kemp RA

更新日期：2018-10-15 00:00:00

abstract：:It has been suggested that phytoestrogens protect against hormone-dependent cancers. Lignans are the main class of phytoestrogens in Western diets. We conducted a prospective study of endometrial cancer and circulating levels of the main human lignan, enterolactone. The design was a case-control study nested within 3 ...

journal_title：International journal of cancer

authors： Zeleniuch-Jacquotte A,Lundin E,Micheli A,Koenig KL,Lenner P,Muti P,Shore RE,Johansson I,Krogh V,Lukanova A,Stattin P,Afanasyeva Y,Rinaldi S,Arslan AA,Kaaks R,Berrino F,Hallmans G,Toniolo P,Adlercreutz H

更新日期：2006-11-15 00:00:00

abstract：:Sera from 450 individuals between the age of 1 and 80 years, representing the general population of the Czech Republic, were tested for the presence of antibodies to human-papillomavirus(HPV)-derived antigens. The following antigens were used: (i) HPV1 virions; (ii) HPV16, -18 and -33-virus-like particles (VLP); (iii)...

journal_title：International journal of cancer

authors： Hamsíková E,Ludvíková V,Smahel M,Sapp M,Vonka V

更新日期：1998-08-31 00:00:00

abstract：:Fatty acids play a key role in cellular bioenergetics, membrane biosynthesis and intracellular signaling processes and thus may be involved in cancer development and progression. In the present study, we comprehensively assessed associations of 14,522 common single-nucleotide polymorphisms (SNPs) in 149 genes of the f...

journal_title：International journal of cancer

authors： Dai W,Liu H,Xu X,Ge J,Luo S,Zhu D,Amos CI,Fang S,Lee JE,Li X,Nan H,Li C,Wei Q

更新日期：2019-11-15 00:00:00

abstract：:The acyclic nucleoside phosphonate analogue cidofovir is a broad-spectrum anti-DNA virus agent, which also possesses potent inhibitory activity against various tumors associated with papillomaviruses in animal models and patients. Moreover, we recently described the potent inhibition of polyomavirus (PyV)-induced hema...

journal_title：International journal of cancer

authors： Liekens S,Verbeken E,De Clercq E,Neyts J

更新日期：2001-04-15 00:00:00

abstract：:Rab11-FIP2 can interact with MYO5B and plays an important role in regulating plasma membrane recycling. Our previous study has shown that MYO5B is epigenetically silenced and associated with c-Met signaling in human gastric cancer. However, little is known of the function of Rab11-FIP2 in gastric cancer. In this study...

journal_title：International journal of cancer

authors： Dong W,Qin G,Shen R

更新日期：2016-04-01 00:00:00

abstract：:Classical Hodgkin lymphoma (HL) is characterized by the presence of Hodgkin and Reed-Sternberg cells (H&RS) and a prominent lymphocytic infiltration. We previously reported Hodgkin-like adult T-cell leukemia/lymphoma (HL-like ATLL) (new WHO classification). Various CXC and CC chemokines are expressed on H&RS cells and...

journal_title：International journal of cancer

authors： Ohshima K,Karube K,Hamasaki M,Suefuji H,Tutiya T,Yamaguchi T,Suzumiya J,Kikuchi M

更新日期：2003-09-20 00:00:00

abstract：:Our study demonstrates that synthetic sialyl Lewis X (SLex) as a ligand for selectins and fibronectin-derived RGDS peptide analogue [Ar(DRGDS)3] inhibits lung metastases produced by i.v. co-injection of B16-BL6 melanoma cells. To investigate the inhibitory mechanisms in a living animal, we performed positron-emission ...

journal_title：International journal of cancer

authors： Saiki I,Koike C,Obata A,Fujii H,Murata J,Kiso M,Hasegawa A,Komazawa H,Tsukada H,Azuma I,Okada S,Oku N

更新日期：1996-03-15 00:00:00

abstract：:In the 7th edition of the AJCC staging system, the mitotic rate criterion replaced Clark level to increase correct classification of high-risk thin melanoma patients (pT1B). Additionally, sentinel node biopsy (SNB) was recommended for nodal staging of pT1B melanomas. The aim of this article was to evaluate the effects...

journal_title：International journal of cancer

authors： Oude Ophuis CM,Louwman MW,Grünhagen DJ,Verhoef K,van Akkooi AC

更新日期：2017-04-15 00:00:00

abstract：:Phenotypic and functional characteristics of tumor-infiltrating lymphocytes (TIL) obtained from human primary and metastatic liver tumors were studied. Lymphocytes isolated from 18 tumors and autologous (A) peripheral blood (6 cases) were phenotyped by 2-color flow cytometry and cloned in a limiting dilution system, w...

journal_title：International journal of cancer

authors： Shimizu Y,Iwatsuki S,Herberman RB,Whiteside TL

更新日期：1990-11-15 00:00:00

abstract：:The purpose of our study was to investigate a novel therapeutic approach for rhabdomyosarcoma (RMS) in an animal model. The pursuit of new therapeutic modalities for RMS is critically important since this type of tumor is the most common soft tissue sarcoma in children and because patients with metastatic disease may ...

journal_title：International journal of cancer

authors： Kalebic T,Tsokos M,Helman LJ

更新日期：1996-11-27 00:00:00

abstract：:Survivin protein is an attractive candidate for cancer immunotherapy since it is abundantly expressed in most common human cancers and mostly absent in normal adult tissues. Malignant mesothelioma (MM) is a deadly cancer associated with asbestos or erionite exposure for which no successful therapies are currently avai...

journal_title：International journal of cancer

authors： Bertino P,Panigada M,Soprana E,Bianchi V,Bertilaccio S,Sanvito F,Rose AH,Yang H,Gaudino G,Hoffmann PR,Siccardi A,Carbone M

更新日期：2013-08-01 00:00:00

abstract：:Embryonal tumors such as Wilms' tumor (WT), embryonal rhabdomyosarcoma (eRMS) and hepatoblastoma have been thought to have a common pathogenetic mechanism. H19 was found to be inactivated in WT and eRMS either by loss of heterozygosity or by hypermethylation of the maternal allele. We show here that the expression of ...

journal_title：International journal of cancer

authors： Fukuzawa R,Umezawa A,Ochi K,Urano F,Ikeda H,Hata J

更新日期：1999-08-12 00:00:00

abstract：:Stem cell-like cells have recently been identified in melanoma cell lines, but their relevance for melanoma pathogenesis is controversial. To characterize the stem cell signature of melanoma, expression of stem cell markers BMI-1 and nestin was studied in 64 cutaneous melanomas, 165 melanoma metastases as well as 53 m...

journal_title：International journal of cancer

authors： Mihic-Probst D,Kuster A,Kilgus S,Bode-Lesniewska B,Ingold-Heppner B,Leung C,Storz M,Seifert B,Marino S,Schraml P,Dummer R,Moch H

更新日期：2007-10-15 00:00:00

abstract：:Exfoliated nasopharyngeal (NP) cells from 62 normal Cantonese Chinese having IgA/VCA antibodies for more than a year and from 39 similar persons without IgA/VCA antibodies, were tested for the presence of EBV/DNA sequences by spot followed by blot hybridization tests, using the cloned internal repeat of B95-8 viral DN...

journal_title：International journal of cancer

authors： Desgranges C,Pi GH,Bornkamm GW,Legrand C,Zeng Y,de-Thé G

更新日期：1983-11-15 00:00:00