Sex and gender differences in the causes of dementia: a narrative review.

abstract：BACKGROUND:Cardiovascular disease (CVD) is the leading cause of death in women after menopause. In essence major risk factors for CVD are similar in women as for men inclusive of serum lipid perturbations. The effects of estrogens and hormone replacement therapy on lipid metabolism is widely discussed and warrant furth...

journal_title：Maturitas

authors： Nerbrand C,Nyberg P,Nordström L,Samsioe G

更新日期：2002-05-20 00:00:00

abstract：OBJECTIVE:To investigate the relationship between hormone replacement therapy (HRT) and level of cognitive performance intra-individual variability, and interactions with statin use, progesterone therapy and type of menopause. METHODS:A representative sample of 60-64 year olds was recruited from the Canberra and Quean...

journal_title：Maturitas

authors： Low LF,Anstey KJ,Jorm AF,Christensen H,Rodgers B

更新日期：2006-04-20 00:00:00

abstract：:This is a scoping review of the notions of authenticity and citizenship in the context of understanding dementia. Authenticity suggests being true to yourself. Social citizenship suggests engagement, relationships and rights. The literature which links authenticity to dementia is scanty, albeit the notion suggests num...

journal_title：Maturitas

authors： Hughes JC

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:C-telopeptide crosslaps (CTX) and bone-specific alkaline phosphatase (BAP) do not provide sufficient sensitivity and specificity for diagnosis of osteoporosis. Cathepsin K (CatK), osteoprotegerin (OPG), and receptor activator of nuclear factor κB ligand (total (t) and soluble (s) RANKL) play an important rol...

journal_title：Maturitas

authors： Piatek S,Adolf D,Wex T,Halangk W,Klose S,Westphal S,Amthauer H,Winckler S

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVES:Estrogen is often prescribed for symptoms and sequelae of ovarian estrogen loss after menopause. METHODS:To assess efficacy and acceptability of a new, highly soluble estrogen-calcium preparation, we formulated a water-soluble powdered combination of estrogen (0.625 mg estrone piperazine sulfate) and calciu...

journal_title：Maturitas

authors： Downey D,Spencer SJ,Deghenghi R,Jaffe RB

更新日期：2001-04-20 00:00:00

abstract：:The immune system plays an essential role in the tumor progression; not only can it inhibit tumor growth but it can also promote tumor growth by establishing a favorable environment. Tumor cells utilize several strategies to evade the host's immune system, including expression of immunosuppressive molecules such as PD...

journal_title：Maturitas

authors： Kuol N,Stojanovska L,Nurgali K,Apostolopoulos V

更新日期：2017-11-01 00:00:00

abstract：:Stroke represents one of the most important menaces to public health. A number of modifiable and non-modifiable risk factors have been identified and studied in detail; among those, obesity, the new world epidemic, seems to be one of the most important in terms of prevention. The discovery of the secretory role of the...

journal_title：Maturitas

authors： Savopoulos C,Michalakis K,Apostolopoulou M,Miras A,Hatzitolios A

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the putative changes in serum angiotensinase activities (aminopeptidase N, APN; aminopeptidase B, APB; aminopeptidase A, APA; aspartyl aminopeptidase, ASAP) involved in the renin-angiotensin system (RAS) in women with breast cancer treated or not with a neoadjuvant thera...

journal_title：Maturitas

authors： Ramírez-Expósito MJ,Carrera-González Mdel P,Mayas MD,Dueñas B,Martínez-Ferrol J,Martínez-Martos JM

更新日期：2012-05-01 00:00:00

abstract：:Androgen insensitivity syndrome (AIS) is one of the most common sexual developmental disorders. According to the grade of the remaining androgen receptor (AR) function, AIS is classified as complete (CAIS), partial (PAIS) or mild (MAIS). In CAIS, the prevalence of germ cell tumours is increased compared with the gener...

journal_title：Maturitas

authors： Kosti K,Athanasiadis L,Goulis DG

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:A traditional asiatic phytoestrogen-rich diet is associated with a lower incidence of estrogen-dependent cancers and clinical consequences of postmenopausal estrogen deficiency. First Wilcox in 1990, showed an increase of the vaginal cell maturation with phytoestrogens on postmenopausal women, but this has n...

journal_title：Maturitas

authors： Chiechi LM,Putignano G,Guerra V,Schiavelli MP,Cisternino AM,Carriero C

更新日期：2003-08-20 00:00:00

abstract：OBJECTIVES:Study to compare the effects of tibolone and raloxifene on health-related quality of life, sexuality and vaginal atrophy. METHODS:A double-blind, randomized study was conducted in 308 osteopenic, but otherwise healthy, postmenopausal women (mean age 66 years) who received tibolone 1.25mg/day or raloxifene 6...

journal_title：Maturitas

authors： Nijland EA,Weijmar Schultz WC,Davis SR

更新日期：2007-10-20 00:00:00

abstract：:Almost without exception clinical research seeking to evaluate the effectiveness of Chinese medicine relies on TCM textbook knowledge - accessed directly or via practitioners' clinical usage - in order to frame its hypotheses. Recent historical research shows that these textbooks, products of a politically directed pr...

journal_title：Maturitas

authors： Scheid V,Ward T,Tuffrey V

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVES:To test the hypothesis that differences by gender will be observed in the association of hip fracture risk with stages of cognitive impairment; and to explore the association between Petersen's "mild cognitive impairment" (MCI) and DSM-5 "mild neurocognitive disorder" (MND). STUDY DESIGN:A community sample ...

journal_title：Maturitas

authors： Lobo E,Marcos G,Santabárbara J,Lobo-Escolar L,Salvador-Rosés H,De la Cámara C,Lopez-Anton R,Gracia-García P,Lobo-Escolar A,ZARADEMP Workgroup.

更新日期：2018-03-01 00:00:00

abstract：:Similar to their US counterparts, Costa Rican women enter menopause at ∼50 years of age, have similar symptoms, including hot flashes and night sweats, as well as an overall negative attitude toward the menopausal transition. One study of rural women in Monteverde reported that women knew little about the menopausal t...

journal_title：Maturitas

authors： Locklear TD,Doyle BJ,Perez AL,Wicks SM,Mahady GB

更新日期：2017-10-01 00:00:00

abstract：:The pentraxin serum amyloid P component (SAP) is a 9.5Sz1-glycoprotein and it has recently been found to be deposited in atherosclerotic lesions or neurofibrillary tangles, which are related to the aging process and Alzheimer's disease. The level of SAP was measured by micro single radial-immunodiffusion. Sample sera ...

journal_title：Maturitas

authors： Hashimoto S,Katou M,Dong Y,Murakami K,Terada S,Inoue M

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVES:Levonorgestrel (LNG), delivered locally into the uterine cavity has a profound effect on the endometrium. The aim of the study was to use a LNG intrauterine system to treat non-atypical and atypical endometrial hyperplasia in women and to evaluate the long-term cure (remission) rate. METHODS:Each of the 20 ...

journal_title：Maturitas

authors： Wildemeersch D,Janssens D,Pylyser K,De Wever N,Verbeeck G,Dhont M,Tjalma W

更新日期：2007-06-20 00:00:00

abstract：BACKGROUND:Several studies drawn from the Ecuadorian population have previously reported that more than half of mid-aged women present hot flushes, which can impair their quality of life. However up-to-date risk factors for their presence and severity have not been assessed. OBJECTIVE:To assess hot flush frequency and...

journal_title：Maturitas

authors： Chedraui P,Aguirre W,Calle A,Hidalgo L,León-León P,Miranda O,Martínez N,Mendoza M,Narváez J,Sánchez H,Schwager G,Quintero JC,Zambrano B,Aguilar A,Martínez MA,Rivera R,Ruilova I

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:Estrogen replacement therapy (ERT) has been reported to affect blood pressure. Since natriuretic peptides have natriuretic and vasodilatory activity and also inhibit the renin-angiotensin-aldosterone system and lower blood pressure, it was hypothesized that the changes in blood pressure effected by ERT might ...

journal_title：Maturitas

authors： Karjalainen AH,Ruskoaho H,Vuolteenaho O,Heikkinen JE,Bäckström AC,Savolainen MJ,Kesäniemi YA

更新日期：2004-03-15 00:00:00

abstract：OBJECTIVES:There is an assumption in menopause research that attitudes to menopause are influenced by a range of cultural, social and psychological variables, which may in turn affect menopausal experience and symptom reporting. However, many studies draw conclusions about this relationship without explicitly examining...

journal_title：Maturitas

authors： Ayers B,Forshaw M,Hunter MS

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:The goal of this study was to search the effects of two different doses of tibolone on endometrial IGF-1 and IGFBP-1 levels in ovariectomized rats. METHODS:Eighteen adult, female, 80-90-days-old, Wistar rats with an average weight of 250 g underwent bilateral ovariectomy under general anesthesia. After waiti...

journal_title：Maturitas

authors： Kuşcu NK,Koyuncu FM,Inan S,Tuglu I,Uyar Y,Ozbilgin K

更新日期：2002-07-25 00:00:00

abstract：BACKGROUND:Depression is related to increased morbidity and mortality in the general population and among patients with coronary artery disease (CAD). The prevalence of major depression is two-times higher in women than men in the general population, but whether this pattern holds true in the CAD population has not bee...

journal_title：Maturitas

authors： Shanmugasegaram S,Russell KL,Kovacs AH,Stewart DE,Grace SL

更新日期：2012-12-01 00:00:00

abstract：:The increasing prevalence of diabetes especially type 2 diabetes worldwide is indisputable. Diabetics suffer increased morbidity and mortality, compared to their non-diabetic counterparts, not only because of vascular complications, but also because of an increased fracture incidence. Both types 1 and 2 diabetes and s...

journal_title：Maturitas

authors： Antonopoulou M,Bahtiyar G,Banerji MA,Sacerdote AS

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Given the asymptomatic nature of osteoporosis, a fragility fracture provides an opportunity to make the issue of osteoporosis relevant to patients. Patients who link their fragility fracture with osteoporosis are more likely to initiate osteoporosis treatment, yet to date, we know little about who is likely t...

journal_title：Maturitas

authors： Sujic R,Gignac MA,Cockerill R,Beaton DE

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:Social support interventions for caregivers of persons with dementia (PwD) are important because informal carers often rely on their social networks for support. This systematic review synthesises findings from research on social support interventions, and examines their methodological quality and effectivene...

journal_title：Maturitas

authors： Dam AE,de Vugt ME,Klinkenberg IP,Verhey FR,van Boxtel MP

更新日期：2016-03-01 00:00:00

abstract：:Dementia affects approximately 6.5% of people over the age of 65. Whilst cognitive impairment is central to the dementia concept, neuropsychiatric symptoms are invariably present at some stage of the illness. Neuropsychiatric symptoms result in a number of negative outcomes for the individual and their caregivers and ...

journal_title：Maturitas

authors： Ford AH

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVES:To examine the potential of a new matrix system developed for estradiol delivery to cause microbial proliferation under the occluded site or to cause acute phototoxicity reactions. METHODS:Twenty healthy post-menopausal women participated in a microbial proliferation study and 11 in a phototoxicity study. B...

journal_title：Maturitas

authors： Mulberry GK,Della-Cioppa G,Monza G,Harper RA,Oelrich DM

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVE:New regimens and routes of administration of hormonal replacement therapy (HRT) in climateric women are becoming available. Since there is no information on the neuroendocrine effects of sequential combined treatment with 17 beta-estradiol and a progestin, the present study evaluated the neuroendocrine, clini...

journal_title：Maturitas

authors： Stomati M,Bersi C,Rubino S,Palumbo M,Comitini G,Genazzani AD,Santuz M,Petraglia F,Genazzani AR

更新日期：1997-12-15 00:00:00

abstract：:The effect of two forms of exogenous estrogen and a placebo on diastolic blood pressure and bodyweight was evaluated in 50 oophorectomized women. There was no significant change in bodyweight on any form of treatment, nor was there any significant elevation in mean diastolic blood pressure. However, 2 out of 49 female...

journal_title：Maturitas

authors： Utian WH

更新日期：1978-06-01 00:00:00

abstract：OBJECTIVES:The objectives of the study were to find the prevalence of major depressive disorder (MDD) in male climacteric outpatients in Japan, and to determine whether symptoms on the Aging Males' Symptoms (AMS) scale scores differed between patients with and without MDD, with the aim of increasing the specificity of ...

journal_title：Maturitas

authors： Yoshida NM,Kumano H,Kuboki T

更新日期：2006-01-20 00:00:00

abstract：:Combination therapy strategies for osteoporosis are reviewed in this article. Regimens including two antiresorptives agents increase BMD more than single therapy alone, but they have not proved to reduce fracture risk. The alternative of combining antiresorptives together with anabolics has gained more interest. There...

journal_title：Maturitas

authors： Garcés C,García LE

更新日期：2006-04-20 00:00:00