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Risk factors related to the presence and severity of hot flushes in mid-aged Ecuadorian women.

Abstract：

BACKGROUND:Several studies drawn from the Ecuadorian population have previously reported that more than half of mid-aged women present hot flushes, which can impair their quality of life. However up-to-date risk factors for their presence and severity have not been assessed. OBJECTIVE:To assess hot flush frequency and intensity and related risk factors among middle-aged Ecuadorian women. METHODS:In this cross-sectional study, 1154 healthy women aged 40-59 years, visiting healthcare centers of eight main cities of Ecuador with more than 100,000 inhabitants, were assessed with the first item of the Menopause Rating Scale (MRS) and a questionnaire containing female and partner socio-demographic data. RESULTS:Mean age of the entire sample was 48.8+/-5.6 years (median 48), a 48.7% had 12 or less years of schooling, 52.8% were postmenopausal, 43.6% lived at high altitude, 56.8% were married and 10% were on hormonal therapy (HT). Hot flushes accounted for 56% (n=646) of the whole sample, of which 29.1% and 9.1% were respectively graded as severe and very severe. Logistic regression determined that female sedentarism (OR: 2.42, CI 95% [1.63-3.59]), accessing a free healthcare system (OR: 1.96, CI 95% [1.30-2.96]), living at high altitude (OR: 1.82, CI 95% [1.14-2.90]) and having a partner abusing alcohol (OR: 1.92, CI 95% [1.09-3.35]) were significant risk factors related to the presence of hot flushes. The regression model also determined that among women with hot flushes (n=646), sedentarism (OR: 1.73, CI 95% [1.14-2.62]) and having a partner with erectile dysfunction (OR: 2.57, CI 95% [1.44-4.59]) were significant risk factors related to severe/very severe hot flushes whereas married status (OR: 0.53, CI 95% [0.32-0.86]), living at high altitude (OR: 0.46, CI 95% [0.26-0.78]) and partner healthiness (OR: 0.59, CI 95% [0.36-0.95]) were not. CONCLUSION:To the best of our knowledge this is the first and largest study assessing hot flushes in a mid-aged Ecuadorian population. We found that the presence and severity were not significantly related to age and hormonal status yet to other individual female/male characteristics and the demography of the studied population.

journal_name

Maturitas

journal_title

Maturitas

authors

Chedraui P,Aguirre W,Calle A,Hidalgo L,León-León P,Miranda O,Martínez N,Mendoza M,Narváez J,Sánchez H,Schwager G,Quintero JC,Zambrano B,Aguilar A,Martínez MA,Rivera R,Ruilova I

doi

10.1016/j.maturitas.2009.11.024

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

378-82

issue

eissn

0378-5122

issn

1873-4111

pii

S0378-5122(09)00449-6

journal_volume

pub_type

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Risk factors related to the presence and severity of hot flushes in mid-aged Ecuadorian women.