Combination of anabolic and antiresorptive agents for the treatment of osteoporosis.

abstract：OBJECTIVE:Physical and psychological incapacity, including fear of falling is related to decreased satisfaction with life in osteoporosis (OP). The impact of a balance exercise program on improving the quality of life is not well established. We have, therefore, investigated the effect of 12-month Balance Training Prog...

journal_title：Maturitas

authors： Madureira MM,Bonfá E,Takayama L,Pereira RM

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVES:Bone mineral density (BMD) and development of osteoporosis are partly determined by genetic factors. The associations between one of suggested candidate, apolipoprotein E (apo E) genotype to bone mineral density (BMD) and bone biochemical markers was studied in 464 subjects recruited from a population-based ...

journal_title：Maturitas

authors： Heikkinen AM,Kröger H,Niskanen L,Komulainen MH,Ryynänen M,Parviainen MT,Tuppurainen MT,Honkanen R,Saarikoski S

更新日期：2000-01-15 00:00:00

abstract：:An open prospective multicentric trial has been conducted over 6 months in 241 postmenopausal volunteers. One-hundred forty-one women had an intact uterus. All patients received a fixed peroral combination of conjugated estrogens CE (1.25 mg per day from day 1 to day 21) and medrogestone (5 mg per day from day 12 to d...

journal_title：Maturitas

authors： Haenggi W,Birkhaeuser MH

更新日期：1993-03-01 00:00:00

abstract：:The pentraxin serum amyloid P component (SAP) is a 9.5Sz1-glycoprotein and it has recently been found to be deposited in atherosclerotic lesions or neurofibrillary tangles, which are related to the aging process and Alzheimer's disease. The level of SAP was measured by micro single radial-immunodiffusion. Sample sera ...

journal_title：Maturitas

authors： Hashimoto S,Katou M,Dong Y,Murakami K,Terada S,Inoue M

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the effects of different types of hormone replacement therapy (HRT) on mammographic density. MATERIALS AND METHODS:In a prospective 1-year study, 103 postmenopausal women were randomized to receive tibolone 2.5 mg/die, continuous conjugated equine estrogens 0.625 mg/die ...

journal_title：Maturitas

authors： Marchesoni D,Driul L,Ianni A,Fabiani G,Della Martina M,Zuiani C,Bazzocchi M

更新日期：2006-01-10 00:00:00

abstract：OBJECTIVE:Mandibular indices, measured on panoramic radiographs, may be useful screening implements for low skeletal bone mass density (BMD). Recent studies suggest that radiographic examination of mandible may constitute an effective process for the early diagnosis of osteoporosis. Biochemical markers of bone turnover...

journal_title：Maturitas

authors： Vlasiadis KZ,Damilakis J,Velegrakis GA,Skouteris CA,Fragouli I,Goumenou A,Matalliotakis J,Koumantakis EE

更新日期：2008-03-20 00:00:00

abstract：:The present study had two objectives: (1) to register the prevalence of a number of climacteric complaints in a Danish general population cohort and (2) retrospectively to test the validity of an association between climacteric complaints, menopausal development, occurrence of life events and social background. A post...

journal_title：Maturitas

authors： Køster A,Davidsen M

更新日期：1993-11-01 00:00:00

abstract：:This is a scoping review of the notions of authenticity and citizenship in the context of understanding dementia. Authenticity suggests being true to yourself. Social citizenship suggests engagement, relationships and rights. The literature which links authenticity to dementia is scanty, albeit the notion suggests num...

journal_title：Maturitas

authors： Hughes JC

更新日期：2019-07-01 00:00:00

abstract：:The uterine environment is often viewed as a relatively safe haven, being guarded by the placenta which acts as a filter, permitting required materials to enter and unwanted products to be removed. However, this defensive barrier is sometimes breached by potential chemical hazards to which the mother may be subjected....

journal_title：Maturitas

authors： Waring RH,Harris RM,Mitchell SC

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to examine the expression of oestrogen regulated genes in premenopausal and postmenopausal normal and malignant endometrial specimens. The molecular mechanisms and the role of these genes in endometrial carcinogenesis are poorly understood. METHODS:Normal and malignant endometrial ...

journal_title：Maturitas

authors： O'Toole SA,Dunn E,Sheppard BL,Sheils O,O'Leary JJ,Wuttke W,Seidlova-Wuttke D

更新日期：2005-06-16 00:00:00

abstract：:The effect of two forms of exogenous estrogen and a placebo on diastolic blood pressure and bodyweight was evaluated in 50 oophorectomized women. There was no significant change in bodyweight on any form of treatment, nor was there any significant elevation in mean diastolic blood pressure. However, 2 out of 49 female...

journal_title：Maturitas

authors： Utian WH

更新日期：1978-06-01 00:00:00

abstract：:The explanations so far proposed for the effects of oestrogens on bone metabolism in post-menopausal women have been based on the changes seen in calciotrophic hormones. However, we demonstrated in a previous study [6] that there is a decrease in the concentration of somatomedin (an insulin-like growth factor) and an ...

journal_title：Maturitas

authors： Duursma SA,Bijlsma JW,van Paassen HC,Slootweg MC

更新日期：1986-03-01 00:00:00

abstract：AIMS:Women in the West can now expect to live one third of their life in a postmenopausal state, and consequently in a state of estrogen deficiency. This can have a number of consequences, and many women suffer vasomotor symptoms during the climacteric. Estrogen deficiency can also result in changes to the skin, hair, ...

journal_title：Maturitas

authors： Palacios S

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to document sexual function in Kelantanese postmenopausal women. METHOD:A semi-structured questionnaire in Malay language was administered to 326 women (mean age of 57.1+/-6.58 (S.D.) years) residing in Kelantan. The subjects comprised of naturally menopaused, healthy women. RESULT...

journal_title：Maturitas

authors： Dhillon HK,Singh HJ,Ghaffar NA

更新日期：2005-11-01 00:00:00

abstract：:End-of-life (EoL) care1 is increasingly used as a generic term in preference to palliative care or terminal care, particularly with reference to individuals with chronic disease, who are resident in community and long-term care (LTC) settings. This review evaluates studies based on patient reported outcome measures (P...

journal_title：Maturitas

authors： Kearns T,Cornally N,Molloy W

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:The aim of this prospective 3-year clinical study was to examine the effect of hormone replacement therapy (HRT) on uterine fibroid growth among postmenopausal women. METHODS:Thirty-seven postmenopausal women with uterine solitary fibroids were recruited randomly for HRT in a 3-year program. All participants...

journal_title：Maturitas

authors： Yang CH,Lee JN,Hsu SC,Kuo CH,Tsai EM

更新日期：2002-09-30 00:00:00

abstract：:Dementia has often thought to be unavoidable and incurable. In recent years, risk factors, including lifestyle attributes, have been associated with the two commonest forms of dementia, Alzheimer's Disease and vascular dementia. There is also new evidence that the adult brain maintains plasticity and response to exter...

journal_title：Maturitas

authors： Flicker L

更新日期：2009-08-20 00:00:00

abstract：:Forty-nine immigrated South-American (SA) and 48 Swedish women, aged 42-67 years, were studied in a comparative semi-structured interview survey, concerning the climacteric and its treatment. The mean age at natural menopause was 47 for the South-American women and 50 for the Swedish women. The prevalence of moderate ...

journal_title：Maturitas

authors： Nedstrand E,Ekseth U,Lindgren R,Hammar M

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease (CVD) is the leading cause of death in women after menopause. In essence major risk factors for CVD are similar in women as for men inclusive of serum lipid perturbations. The effects of estrogens and hormone replacement therapy on lipid metabolism is widely discussed and warrant furth...

journal_title：Maturitas

authors： Nerbrand C,Nyberg P,Nordström L,Samsioe G

更新日期：2002-05-20 00:00:00

abstract：:At least 16 million women over the age of 50 currently experience low sexual desire, with approximately 4 million women exhibiting hypoactive sexual desire disorder (HSDD). Although early research established that testosterone therapy improves sexual desire in postmenopausal women, safer and more efficacious administr...

journal_title：Maturitas

authors： Krapf JM,Simon JA

更新日期：2009-07-20 00:00:00

abstract：:In direct contrast to the observational studies, both primary and secondary prevention trials of female reproductive hormones have found no benefit for coronary heart disease (CHD). Basic science studies have elucidated several mechanisms by which estrogen may improve coronary arterial physiology and prevent pathology...

journal_title：Maturitas

authors： Rossouw JE

更新日期：2005-05-16 00:00:00

abstract：:It is important for our aging population to remain active, particularly those with chronic diseases, like Parkinson disease (PD), which limit mobility. Recent studies in older adults and people with PD suggest dance interventions provide various motor benefits. The literature for dance in PD is growing, but many knowl...

journal_title：Maturitas

authors： McNeely ME,Duncan RP,Earhart GM

更新日期：2015-05-01 00:00:00

abstract：:Menopause marks a time of dramatic hormonal and often social change for women. Both risk factors and health needs are likely to change as women pass through menopause. This paper examines the demographic characteristics of the world population of menopausal and post-menopausal women, and also examines the implication ...

journal_title：Maturitas

authors： Hill K

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:To correlate circulating hormone levels with the clinical and biological features of the tumors in menopausal breast cancer patients. DESIGN:Circulating hormone levels were measured in 161 previously untreated menopausal breast cancer patients within 72 h of their planned surgery. The obtained hormone levels...

journal_title：Maturitas

authors： Schneider J,Martín-Gutiérrez S,Tresguerres JA,García-Velasco JA

更新日期：2009-09-20 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Cutaneous intrinsic ageing has been shown to be improved by hormone replacement therapy (HRT). Photoageing is, however, unresponsive to such treatment. The present double-blind study was undertaken to compare the beneficial effect of a 1-month topical treatment with 0.05% all-trans-retinoic ac...

journal_title：Maturitas

authors： Piérard GE,Henry F,Piérard-Franchimont C

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVES:The purpose of this review is to focus on the importance of metabolic syndrome (MBS) and its increased prevalence in postmenopausal (PM) women. Also the role of hormonal therapy in PM women with MBS will be discussed. METHODS:Review of the relevant literature and results from recent clinical trials. RESULT...

journal_title：Maturitas

authors： Lobo RA

更新日期：2008-05-20 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate gynecologists' knowledge of the WHI study, and its repercussions on their attitudes and practice 3 years after publication. DESIGN:A self-administered, anonymous questionnaire containing 19 questions was sent to 6000 gynecologists, members of the São Paulo Society ...

journal_title：Maturitas

authors： Lazar F Jr,Costa-Paiva L,Morais SS,Pedro AO,Pinto-Neto AM

更新日期：2007-02-20 00:00:00

abstract：:Most health decisions occur in contexts of scientific uncertainty, the "grey zone" of decision-making and many decisions faced by menopausal women are no exception. These contexts are characterized either by scientific evidence that points to a balance between harms and benefits within or between options, or by the ab...

journal_title：Maturitas

authors： Légaré F,Brouillette MH

更新日期：2009-07-20 00:00:00

abstract：OBJECTIVE:In 1990 we initiated a 20 year, partly randomised study (Danish Osteoporosis Prevention Study, DOPS) in order to (a) evaluate clinical, biochemical and osteodensitometric variables as predictors of low bone mass and future osteoporotic fractures, and (b) test the hypothesis, that hormone replacement therapy (...

journal_title：Maturitas

authors： Mosekilde L,Hermann AP,Beck-Nielsen H,Charles P,Nielsen SP,Sørensen OH

更新日期：1999-03-15 00:00:00

abstract：OBJECTIVES:It is still controversial whether hormone replacement therapy (HRT) can affect the onset of uterine myomas or their growth in postmenopause. It is likely that some therapeutic schedules can influence the myometrial growth differently, due to a more potent stimulation of the uterine receptors. The aim of the ...

journal_title：Maturitas

authors： Polatti F,Viazzo F,Colleoni R,Nappi RE

更新日期：2000-11-30 00:00:00