Synthesis and characterization of modified starch/polybutadiene as novel transdermal drug delivery system.

Abstract:

:Transdermal drug delivery systems are topically administered medicaments in the form of patches that deliver drugs for systemic effects at a predetermined and controlled rate. It works very simply in which drug is applied inside the patch and it is worn on skin for long period of time. Polymer matrix, drug, permeation enhancers are the main components of transdermal drug delivery systems. The objective of the present study was to develop the modified starch and 1,4-cis polybutadiene nanoparticles as novel polymer matrix system. We have been studied the properties of a novel transdermal drug delivery system with clonidine as drug model.

journal_name

Int J Biol Macromol

authors

Saboktakin MR,Akhyari S,Nasirov FA

doi

10.1016/j.ijbiomac.2014.05.062

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

442-6

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(14)00358-4

journal_volume

69

pub_type

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