Abstract:
:The world's coastal zones are experiencing rapid development and an increase in storms and flooding. These hazards put coastal communities at heightened risk, which may increase with habitat loss. Here we analyse globally the role and cost effectiveness of coral reefs in risk reduction. Meta-analyses reveal that coral reefs provide substantial protection against natural hazards by reducing wave energy by an average of 97%. Reef crests alone dissipate most of this energy (86%). There are 100 million or more people who may receive risk reduction benefits from reefs or bear hazard mitigation and adaptation costs if reefs are degraded. We show that coral reefs can provide comparable wave attenuation benefits to artificial defences such as breakwaters, and reef defences can be enhanced cost effectively. Reefs face growing threats yet there is opportunity to guide adaptation and hazard mitigation investments towards reef restoration to strengthen this first line of coastal defence.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Ferrario F,Beck MW,Storlazzi CD,Micheli F,Shepard CC,Airoldi Ldoi
10.1038/ncomms4794subject
Has Abstractpub_date
2014-05-13 00:00:00pages
3794issn
2041-1723pii
ncomms4794journal_volume
5pub_type
杂志文章abstract::Rheb is a small GTP-binding protein and its GTPase activity is activated by the complex of Tsc1 and Tsc2 whose mutations cause tuberous sclerosis complex (TSC). We previously reported that cultured TSC neurons showed impaired spine synapse morphogenesis in an mTORC1-independent manner. Here we show that the PDZ protei...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7842
更新日期:2015-04-16 00:00:00
abstract::Orexins are associated with drug relapse in rodents. Here, we show that acute restraint stress in mice activates lateral hypothalamic (LH) orexin neurons, increases levels of orexin A and 2-arachidonoylglycerol (2-AG) in the ventral tegmental area (VTA), and reinstates extinguished cocaine-conditioned place preference...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12199
更新日期:2016-07-22 00:00:00
abstract::The T helper 9 (Th9) cell transcriptional network is formed by an equilibrium of signals induced by cytokines and antigen presentation. Here we show that, within this network, two interferon regulatory factors (IRF), IRF1 and IRF4, display opposing effects on Th9 differentiation. IRF4 dose-dependently promotes, wherea...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15366
更新日期:2017-05-12 00:00:00
abstract::Variation in body iron is associated with or causes diseases, including anaemia and iron overload. Here, we analyse genetic association data on biochemical markers of iron status from 11 European-population studies, with replication in eight additional cohorts (total up to 48,972 subjects). We find 11 genome-wide-sign...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5926
更新日期:2014-10-29 00:00:00
abstract::Thrombocytosis is present in more than 30% of patients with solid malignancies and correlates with worsened patient survival. Tumor cell interaction with various cellular components of the tumor microenvironment including platelets is crucial for tumor growth and metastasis. Although it is known that platelets can inf...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00411-z
更新日期:2017-08-21 00:00:00
abstract::Cytosolic HSP90 requires multiple cochaperones in folding client proteins. However, the function of gp96 (HSP90b1, grp94), an HSP90 paralogue in the endoplasmic reticulum (ER), is believed to be independent of cochaperones. Here, we demonstrate that gp96 chaperones multiple Toll-like receptors (TLRs), but not TLR3, in...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1070
更新日期:2010-09-21 00:00:00
abstract::High-harmonic generation (HHG) in gases has been the main enabling technology of attosecond science since its discovery. Recently, HHG from solids has been demonstrated, opening a lively area of research. In contrast, harmonic generation from liquids has so far remained restricted to low harmonics in the visible regim...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06040-4
更新日期:2018-09-13 00:00:00
abstract::Plasmodium vivax poses unique challenges for malaria control and elimination, notably the potential for relapses to maintain transmission in the face of drug-based treatment and vector control strategies. We developed an individual-based mathematical model of P. vivax transmission calibrated to epidemiological data fr...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05860-8
更新日期:2018-08-17 00:00:00
abstract::COVID-19, caused by SARS-CoV-2, lacks effective therapeutics. Additionally, no antiviral drugs or vaccines were developed against the closely related coronavirus, SARS-CoV-1 or MERS-CoV, despite previous zoonotic outbreaks. To identify starting points for such therapeutics, we performed a large-scale screen of electro...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18709-w
更新日期:2020-10-07 00:00:00
abstract::In the quantum Hall regime, near integer filling factors, electrons should only be transmitted through spatially separated edge states. However, in mesoscopic systems, electronic transmission turns out to be more complex, giving rise to a large spectrum of magnetoresistance oscillations. To explain these observations,...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1038
更新日期:2010-07-27 00:00:00
abstract::Since the observation of the first brown dwarf in 1995, numerous studies have led to a better understanding of the structures of these objects. Here we present a method for studying material resistivity in warm dense plasmas in the laboratory, which we relate to the microphysics of brown dwarfs through viscosity and e...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9742
更新日期:2015-11-06 00:00:00
abstract::Protein function and dynamics are closely related; however, accurate dynamics information is difficult to obtain. Here based on a carefully assembled data set derived from experimental data for proteins in solution, we quantify backbone dynamics properties on the amino-acid level and develop DynaMine--a fast, high-qua...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3741
更新日期:2013-01-01 00:00:00
abstract::The change of global-mean precipitation under global warming and interannual variability is predominantly controlled by the change of atmospheric longwave radiative cooling. Here we show that tightening of the ascending branch of the Hadley Circulation coupled with a decrease in tropical high cloud fraction is key in ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15771
更新日期:2017-06-07 00:00:00
abstract::In healthy blood vessels with a laminar blood flow, the endothelial cell division rate is low, only sufficient to replace apoptotic cells. The division rate significantly increases during embryonic development and under halted or turbulent flow. Cells in barrier tissue are connected and their motility is highly correl...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6720
更新日期:2014-12-08 00:00:00
abstract::Stable water isotope records from Antarctica are key for our understanding of Quaternary climate variations. However, the exact quantitative interpretation of these important climate proxy records in terms of surface temperature, ice sheet height and other climatic changes is still a matter of debate. Here we report r...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05430-y
更新日期:2018-08-30 00:00:00
abstract::Chemoproteomics is a key technology to characterize the mode of action of drugs, as it directly identifies the protein targets of bioactive compounds and aids in the development of optimized small-molecule compounds. Current approaches cannot identify the protein targets of a compound and also detect the interaction s...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18071-x
更新日期:2020-08-21 00:00:00
abstract::The superconducting state is formed by the condensation of Cooper pairs and protected by the superconducting gap. The pairing interaction between the two electrons of a Cooper pair determines the gap function. Thus, it is pivotal to detect the gap structure for understanding the mechanism of superconductivity. In cupr...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09340-5
更新日期:2019-04-08 00:00:00
abstract::The downstream consequences of inflammation in the adult mammalian heart are formation of a non-functional scar, pathological remodelling and heart failure. In zebrafish, hydrogen peroxide released from a wound is the initial instructive chemotactic cue for the infiltration of inflammatory cells, however, the identity...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3081
更新日期:2013-01-01 00:00:00
abstract::Organic conjugated polymers demonstrate great potential in transistors, solar cells and light-emitting diodes, whose performances are fundamentally governed by charge transport. However, the morphology-property relationships and the underpinning charge transport mechanisms remain unclear. Particularly, whether the non...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20238-5
更新日期:2021-01-04 00:00:00
abstract::Quasicrystals, materials with aperiodic long-range order, have been found in intermetallics, soft materials such as colloids and supermolecules, and also in two-dimensional monolayer films. Here we present the first example of three-dimensional growth of a single-element quasicrystalline film. Using a hitherto unexplo...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3715
更新日期:2013-01-01 00:00:00
abstract::The low-energy elementary excitations in frustrated quantum magnets have fascinated researchers for decades. In frustrated Ising magnets on a pyrochlore lattice possessing macroscopically degenerate spin-ice ground states, the excitations have been discussed in terms of classical magnetic monopoles, which do not conta...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10807
更新日期:2016-02-25 00:00:00
abstract::Carotenoid cleavage dioxygenases (CCDs) form hormones and signaling molecules. Here we show that a member of an overlooked plant CCD subfamily from rice, that we name Zaxinone Synthase (ZAS), can produce zaxinone, a novel apocarotenoid metabolite in vitro. Loss-of-function mutants (zas) contain less zaxinone, exhibit ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08461-1
更新日期:2019-02-18 00:00:00
abstract::Collective cell migration mediates multiple tissue morphogenesis processes. Yet how multi-dimensional mesenchymal cell movements are coordinated remains mostly unknown. Here we report that coordinated mesenchymal cell migration during chicken feather elongation is accompanied by dynamic changes of bioelectric currents...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07661-5
更新日期:2018-12-18 00:00:00
abstract::The sensitivity of quantum magnetometer is challenged by control errors and, especially in the solid state, by their short coherence times. Refocusing techniques can overcome these limitations and improve the sensitivity to periodic fields, but they come at the cost of reduced bandwidth and cannot be applied to sense ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2375
更新日期:2013-01-01 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Nature communications
pub_type: 已发布勘误
doi:10.1038/s41467-020-19626-8
更新日期:2020-11-03 00:00:00
abstract::Alike materials in the solid state, the phase diagram of type-II superconductors exhibit crystalline, amorphous, liquid and spatially inhomogeneous phases. The multitude of different phases of vortex matter has thence proven to act as almost ideal model system for the study of both the underlying properties of superco...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9813
更新日期:2015-11-02 00:00:00
abstract::Functional blood vessel growth depends on generation of distinct but coordinated responses from endothelial cells. Bone morphogenetic proteins (BMP), part of the TGFβ superfamily, bind receptors to induce phosphorylation and nuclear translocation of SMAD transcription factors (R-SMAD1/5/8) and regulate vessel growth. ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13247
更新日期:2016-11-11 00:00:00
abstract::Acoustical tweezers open major prospects in microbiology for cells and microorganisms contactless manipulation, organization and mechanical properties testing since they are biocompatible, label-free and have the potential to exert forces several orders of magnitude larger than their optical counterpart at equivalent ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18000-y
更新日期:2020-08-25 00:00:00
abstract::Single-nucleotide variants that underlie phenotypic variation can affect chromatin occupancy of transcription factors (TFs). To delineate determinants of in vivo TF binding and chromatin accessibility, we introduce an approach that compares ChIP-seq and DNase-seq data sets from genetically divergent murine erythroid c...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03082-6
更新日期:2018-02-22 00:00:00
abstract::One of the most dramatic events in river environments is the natural diversion, or avulsion, of a channel across its floodplain. Though rarely witnessed, avulsions can cause massive floods, and over geologic time they create most of the fluvial stratigraphic record. Avulsions exhibit behavior ranging from reoccupying ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15859-9
更新日期:2020-04-30 00:00:00