The bactericidal activity of DR-3355, an optically active isomer of ofloxacin.

abstract：:DNA hybridisation of 309 consecutive Staphylococcus aureus clinical isolates with oligonucleotide probes specific for genes encoding Panton-Valentine leucocidin (luk-PV) and gamma-haemolysin (hlg) revealed that 99% of randomly selected strains carried the hlg locus whereas only 2% harboured the luk-PV as well as the h...

journal_title：Journal of medical microbiology

authors： Prevost G,Couppie P,Prevost P,Gayet S,Petiau P,Cribier B,Monteil H,Piemont Y

更新日期：1995-04-01 00:00:00

abstract：:Infection of humans by Abiotrophia defectiva, a nutritionally variant streptococcus, most commonly takes the form of endocarditis, though a variety of other manifestations ranging from central nervous system abscesses to orthopaedic infections have been seen. We report here what we believe is the first case of bullous...

journal_title：Journal of medical microbiology

authors： Anderson HM,Miller C,Kemp E,Huntington MK

更新日期：2012-07-01 00:00:00

abstract：:The global emergence of antibiotic-resistant strains of Pseudomonas aeruginosa poses a major threat in both hospital environments and the community. P. aeruginosa is an opportunistic human pathogen, and it also infects a wide range of model organisms including the nematode Caenorhabditis elegans. Quorum sensing (QS) m...

journal_title：Journal of medical microbiology

authors： Ganesh PS,Rai RV

更新日期：2016-12-01 00:00:00

abstract：:Epidemic methicillin-resistant Staphylococcus aureus types 15 and 16 (EMRSA-15 and EMRSA-16) are the dominant types of MRSA found in UK hospitals, but accurate designation of strains has been difficult. Restriction fragment length polymorphism (RFLP) profiles of seven core virulence genes were used to classify unambig...

journal_title：Journal of medical microbiology

authors： Moore PCL,Lindsay JA

更新日期：2002-06-01 00:00:00

abstract：:The inhibitory effect of human immunodeficiency virus (HIV) proteinase inhibitors amprenavir and saquinavir and antifungal agents terbinafine, ketoconazole, amphotericin B and ciclopiroxolamine on aspartyl proteinases (Saps) secreted by Candida albicans was tested in an in vitro spectophotometric assay. As expected, b...

journal_title：Journal of medical microbiology

authors： Schaller M,Krnjaic N,Niewerth M,Hamm G,Hube B,Korting HC

更新日期：2003-03-01 00:00:00

abstract：:Iliopsoas abscess is usually secondary to the spread of infection from a contiguous focus. Primary disease is uncommon, except in children where Staphylococcus aureus is the main pathogen. We report a 60-year-old woman who developed a primary iliopsoas abscess as a result of haematogenous spread of Capnocytophaga sput...

journal_title：Journal of medical microbiology

authors： Chan JFW,Wong SSY,Leung SSM,Li IWS,To KKW,Cheng VCC,Yuen KY

更新日期：2010-11-01 00:00:00

abstract：:As well as conventional methods such as immunodiffusion, ELISA, or agglutination for the detection of toxin production in Staphylococcus aureus, amplification techniques like PCR allow a very sensitive and specific identification of the genes responsible for enterotoxin B and C, and TSST-1 production. These toxins mig...

journal_title：Journal of medical microbiology

authors： Schmitz FJ,Steiert M,Hofmann B,Verhoef J,Hadding U,Heinz HP,Köhrer K

更新日期：1998-04-01 00:00:00

abstract：:A collection of 72 strains of catalase-negative gram-positive, -negative and -variable cocco-bacilli isolated from samples of vaginal discharge from women with non-specific vaginal infection was examined in an attempt to develop an identification system for Gardnerella vaginalis that could be used in a diagnostic labo...

journal_title：Journal of medical microbiology

authors： Taylor E,Phillips I

更新日期：1983-02-01 00:00:00

abstract：:Campylobacter jejuni is a frequent cause of infectious diarrhoea and is increasingly recognized as a trigger for late-onset complications. The poor standardization of commonly used serological tests might explain the conflicting results regarding the frequency of antecedent C. jejuni infections in defined patient grou...

journal_title：Journal of medical microbiology

authors： Schmidt-Ott R,Brass F,Scholz C,Werner C,Groß U

更新日期：2005-08-01 00:00:00

abstract：:A male patient of 32 years was referred for surgical drainage and orchidectomy of the right testis following a cycling injury. A Venereal Disease Research Laboratory (VDRL) test was requested by the surgery department to rule out secondary syphilis. Although serum samples gave a negative result in the VDRL test, quali...

journal_title：Journal of medical microbiology

authors： Purwar S,Metgud SC,Gokale SK

更新日期：2012-03-01 00:00:00

abstract：:Streptococcus gordonii produces a pheromone heptapeptide, s.g.cAM373, which induces a conjugative mating response in Enterococcus faecalis cells carrying the responsive plasmid, pAM373. We investigated the extent of this intergeneric signaling on DNA acquisition by streptococcal species likely to cohabit oral biofilms...

journal_title：Journal of medical microbiology

authors： Mansfield JM,Herrmann P,Jesionowski AM,Vickerman MM

更新日期：2017-11-01 00:00:00

abstract：:Active efflux has an important role in the antimicrobial resistance of Campylobacter jejuni and Campylobacter coli. The effects of two putative efflux pump inhibitors (EPIs), phenylalanine-arginine β-naphthylamide and 1-(1-naphthylmethyl)-piperazine, and the effects of inactivation of the cmeB,cmeF and cmeR genes on r...

journal_title：Journal of medical microbiology

authors： Mavri A,Smole Možina S

更新日期：2012-06-01 00:00:00

abstract：:This study used a previously described multiplex PCR-based reverse line blot (mPCR/RLB) assay to assess the prevalence and distribution of 14 urogenital pathogens or putative pathogens, namely Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Trichomonas vaginalis, Gardnerella va...

journal_title：Journal of medical microbiology

authors： McKechnie ML,Hillman RJ,Jones R,Lowe PC,Couldwell DL,Davies SC,King F,Kong F,Gilbert GL

更新日期：2011-07-01 00:00:00

abstract：:Rickettsia conorii is endemic in Greece, though only a few cases of infection have been published to date. The case of a 58-year-old man from northern Greece with a severe form of Mediterranean spotted fever and rapid neurological deterioration is presented here. The patient received antibiotic treatment with doxycycl...

journal_title：Journal of medical microbiology

authors： Tzavella K,Hatzizisis IS,Vakali A,Mandraveli K,Zioutas D,Alexiou-Daniel S

更新日期：2006-03-01 00:00:00

abstract：:Francisella tularensis is a highly virulent intracellular bacterium capable of rapid multiplication in phagocytic cells. Previous studies have revealed that activation of F. tularensis-infected macrophages leads to control of infection and reactive nitrogen and oxygen species make important contributions to the bacter...

journal_title：Journal of medical microbiology

authors： Tancred L,Telepnev MV,Golovliov I,Andersson B,Andersson H,Lindgren H,Sjöstedt A

更新日期：2011-11-01 00:00:00

abstract：:The aim of this study was to examine the frequency and distribution of human verocytotoxigenic Escherichia coli (VTEC) O157 and non-O157 in the Republic of Ireland, and also to examine the presence of virulence genes in these isolates. This genetic information combined with phenotypic tests was used to produce a compl...

journal_title：Journal of medical microbiology

authors： Carroll AM,Gibson A,McNamara EB

更新日期：2005-12-01 00:00:00

abstract：:Oral biofilms are one of the greatest challenges in dental research. The present study aimed to investigate initial bacterial colonization of enamel surfaces in situ using fluorescence in situ hybridization (FISH) over a 12 h period. For this purpose, bovine enamel slabs were fixed on buccal sites of individual splint...

journal_title：Journal of medical microbiology

authors： Al-Ahmad A,Follo M,Selzer AC,Hellwig E,Hannig M,Hannig C

更新日期：2009-10-01 00:00:00

abstract：:Rickettsia rickettsii has limited adverse effects on its arthropod vector, but causes severe disease in man. To model differences in host-parasite interaction, R. rickettsii growth and protein expression were examined at temperatures reflective of host environment in the tick cell lines DALBE3 and IDE2, the human endo...

journal_title：Journal of medical microbiology

authors： Policastro PF,Munderloh UG,Fischer ER,Hackstadt T

更新日期：1997-10-01 00:00:00

abstract：:Faecal specimens from 843 cases of diarrhoea in the community were tested for the presence of Clostridium difficile cytotoxin and Clostridium perfringens enterotoxin. C. difficile cytotoxin was detected in faecal specimens from 0.6 % of cases aged at least 2 years by using a Vero cell assay. Factors associated with de...

journal_title：Journal of medical microbiology

authors： Forward LJ,Tompkins DS,Brett MM

更新日期：2003-09-01 00:00:00

abstract：:Iron is an important nutritional requirement for bacteria due to its conserved role in many essential metabolic processes. As a consequence of the lack of freely available iron in the mammalian host, bacteria upregulate a range of virulence factors during infection. Transcriptional analysis of Francisella tularensis s...

journal_title：Journal of medical microbiology

authors： Milne TS,Michell SL,Diaper H,Wikström P,Svensson K,Oyston PCF,Titball RW

更新日期：2007-10-01 00:00:00

abstract：:Breakthrough contamination of tuberculosis (TB) cultures is a problem in that it allows the overgrowth of another bacterium present in the sputum specimen, which can potentially mask the presence of Mycobacterium tuberculosis. The aim of this study was to isolate and characterize the bacterial organisms responsible fo...

journal_title：Journal of medical microbiology

authors： McClean M,Stanley T,Stanley S,Maeda Y,Goldsmith CE,Shepherd R,Millar BC,Dooley JS,Moore JE

更新日期：2011-09-01 00:00:00

abstract：:This report focuses on the molecular characterization of 22 extended-spectrum beta-lactamase-producing Escherichia coli isolates collected in a German university hospital during a period of 9 months in 2006. Relationship analysis of clinical isolates was done via PFGE, multilocus sequence typing, plasmid profiling and...

journal_title：Journal of medical microbiology

authors： Cullik A,Pfeifer Y,Prager R,von Baum H,Witte W

更新日期：2010-05-01 00:00:00

abstract：:A total of 148 Vibrio cholerae isolates from a major shrimp production area in Southern Thailand were examined by colony hybridisation for genes encoding heat-stable enterotoxin (NAG-ST) and cholera toxin (CT). Only non-O1 V. cholerae strains were found to harbour NAG-ST (14 of 146) whereas no strains hybridised with ...

journal_title：Journal of medical microbiology

authors： Dalsgaard A,Serichantalergs O,Shimada T,Sethabutr O,Echeverria P

更新日期：1995-09-01 00:00:00

abstract：:Administration of oestradiol to three strains of female mice induced the oestrous phase of the reproductive cycle in which there are few or no polymorphonuclear leucocytes (PMNL) in vaginal smears. This treatment rendered the mice susceptible to genital tract colonisation by serotype 8 of Ureaplasma urealyticum, inocu...

journal_title：Journal of medical microbiology

authors： Furr PM,Taylor-Robinson D

更新日期：1989-06-01 00:00:00

abstract：:The potential of exocellular carbohydrate antigens of Staphylococcus epidermidis as markers of infection in bone was investigated by immunoblotting and enzyme-linked immunosorbent assay (ELISA). Exocellular antigens were prepared by gel filtration chromatography of concentrated brain heart infusion culture supernates....

journal_title：Journal of medical microbiology

authors： Lambert PA,Van Maurik A,Parvatham S,Akhtar Z,Fraise AP,Krikler SJ

更新日期：1996-05-01 00:00:00

abstract：:The fungal pathogen Cryptococcus neoformans has a predilection for the central nervous system (CNS), resulting in devastating meningoencephalitis. At present, it is unclear how C. neoformans traverses the blood-brain barrier (BBB) and causes CNS infection. The present study has examined and characterized the interacti...

journal_title：Journal of medical microbiology

authors： Chen SHM,Stins MF,Huang SH,Chen YH,Kwon-Chung KJ,Chang Y,Kim KS,Suzuki K,Jong AY

更新日期：2003-11-01 00:00:00

abstract：:Infections of the parotid gland with non-tuberculous mycobacteria (NTM) are rarely described. Here, we report on an infection of the parotid gland caused by Mycobacterium avium and give a literature-based overview about this entity. In the light of a global increase of mycobacterial infections, unusual manifestations ...

journal_title：Journal of medical microbiology

authors： Gittinger FS,Raible A,Kempf VAJ

更新日期：2008-04-01 00:00:00

abstract：:Catechin, a constituent of tea, possesses various bioactivities. In particular, the most abundant catechin in tea is epigallocatechin gallate (EGCg), which has an anti-inflammatory effect. In the present study, the usability of EGCg for osteomyelitis treatment was examined. Osteomyelitis is a difficult disease to cure...

journal_title：Journal of medical microbiology

authors： Ishida I,Kohda C,Yanagawa Y,Miyaoka H,Shimamura T

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:Sporothrix brasiliensis, a member of the Sporothrix schenckii complex, is a major cause of epidemic outbreaks of sporotrichosis due to its greater virulence and ability to evade the immune system. The absence of studies about this species led to this study, with the aim to evaluate the importance of Toll-like r...

journal_title：Journal of medical microbiology

authors： Rossato L,Silvana Dos Santos S,Ferreira LG,Rogério de Almeida S

更新日期：2019-01-01 00:00:00

abstract：:A novel bunyavirus associated with fever, thrombocytopenia and leukopenia syndrome (FTLS) was discovered in Henan Province, China. Here, we report the development of an assay for this novel bunyavirus based on real-time reverse transcription PCR (RT-PCR). The assay exhibited high sensitivity and specificity without cr...

journal_title：Journal of medical microbiology

authors： Huang X,Liu L,Du Y,Ma H,Mu Y,Pengzhi Wang,Ma H,Tang X,Wang H,Kang K,Zhang S,Wu W,Chen H,Liu G,Yang Y,Yongqiangj,Jiang,Xu B,Chen W

更新日期：2013-07-01 00:00:00