Abstract:
:Many aspects of nucleic acid metabolism, such as DNA replication, repair and transcription, are regulated by the post-translational modifiers ubiquitin and SUMO. Not surprisingly, DNA itself plays an integral part in determining the modification of most chromatin-associated targets. Conversely, ubiquitination or SUMOylation of a protein can impinge on its DNA-binding properties. This review describes mechanistic principles governing the mutual interactions between DNA and ubiquitin or SUMO.
journal_name
Nat Struct Mol Bioljournal_title
Nature structural & molecular biologyauthors
Ulrich HDdoi
10.1038/nsmb.2805subject
Has Abstractpub_date
2014-04-01 00:00:00pages
317-24issue
4eissn
1545-9993issn
1545-9985pii
nsmb.2805journal_volume
21pub_type
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journal_title:Nature structural & molecular biology
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journal_title:Nature structural & molecular biology
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更新日期:2014-10-01 00:00:00
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更新日期:2011-02-01 00:00:00
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journal_title:Nature structural & molecular biology
pub_type: 杂志文章
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更新日期:2016-04-01 00:00:00
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更新日期:2010-10-01 00:00:00
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更新日期:2008-06-01 00:00:00
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更新日期:2004-09-01 00:00:00
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更新日期:2015-05-01 00:00:00
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journal_title:Nature structural & molecular biology
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journal_title:Nature structural & molecular biology
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pub_type: 杂志文章
doi:10.1038/nsmb1042
更新日期:2006-02-01 00:00:00
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journal_title:Nature structural & molecular biology
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更新日期:2015-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1038/nsmb1057
更新日期:2006-02-01 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
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pub_type: 已发布勘误
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更新日期:2020-02-01 00:00:00
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更新日期:2013-02-01 00:00:00
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pub_type: 评论,新闻
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journal_title:Nature structural & molecular biology
pub_type: 杂志文章
doi:10.1038/s41594-020-0472-y
更新日期:2020-10-01 00:00:00
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journal_title:Nature structural & molecular biology
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更新日期:2013-07-01 00:00:00