Abstract:
:Effects of carbofuran commercial formulation on oxidative stress parameters were studied in carps (Cyprinus carpio) exposed to 50µg/L for 7 and 30 days under rice field and laboratory conditions. Thiobarbituric acid reactive substance (TBARS) levels were increased in the brain of fish after 7 and 30 days under rice field and laboratory conditions. In the liver and muscle, TBARS levels increased after 7 and 30 days under laboratory conditions, whereas in rice field the levels increased only after 30 days. Protein carbonyl content in the liver increased after 7 and 30 days under both experimental conditions. Acetylcholinesterase (AChE) activity was decreased in the brain and muscle after 7 and 30 days under both experimental conditions evaluated. The superoxide dismutase (SOD) activity increased in the liver after 7 and 30 days under rice field condition, whereas under laboratory condition this enzyme increased only after 30 days. The catalase (CAT) activity in the liver decreased after 30 days under rice field condition, whereas no changes were observed under laboratory conditions. In rice field, glutathione S-transferase (GST) decreased after 7 days but increased after 30 days, whereas no change was observed in fish exposed to carbofuran under laboratory conditions. These results suggest that environmental relevant carbofuran concentrations may cause oxidative stress, affecting biochemical and enzymatic parameters on carps. Some parameters could be used as biomarkers to carbofuran exposure.
journal_name
Ecotoxicol Environ Safjournal_title
Ecotoxicology and environmental safetyauthors
Clasen B,Leitemperger J,Murussi C,Pretto A,Menezes C,Dalabona F,Marchezan E,Adaime MB,Zanella R,Loro VLdoi
10.1016/j.ecoenv.2013.12.012subject
Has Abstractpub_date
2014-03-01 00:00:00pages
77-82eissn
0147-6513issn
1090-2414pii
S0147-6513(13)00536-8journal_volume
101pub_type
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