[New antiplatelet drugs in coronary artery disease].

Abstract:

:The dual antiplatelet therapy with acetylsalicylic acid and clopidogrel has been the mainstay of both acute and chronic phase coronary artery disease, reducing importantly the risk of adverse events. Despite a correct compliance, a non-negligible rate of adverse events still happens. New compounds, with improved properties, are now clinically available (such as prasugrel or ticagrelor) or under advanced development. The aim of the present review is the description of these new compounds, particularly prasugrel and ticagrelor.

journal_name

Med Clin (Barc)

journal_title

Medicina clinica

authors

Tello-Montoliu A,Jover E,Valdés M

doi

10.1016/j.medcli.2013.12.006

subject

Has Abstract

pub_date

2014-12-09 00:00:00

pages

508-14

issue

11

eissn

0025-7753

issn

1578-8989

pii

S0025-7753(13)00916-0

journal_volume

143

pub_type

杂志文章,评审
  • [New approaches for the treatment of dyslipidemia].

    abstract::Reduction in the risk of cardiovascular complications through modification of lipids is currently focused on lowering low density lipoproteins-cholesterol, with statins being the preferred drugs. New agents, under research, such as antibodies neutralizing PCSK9, will have a special place for the management of patients...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2013.04.026

    authors: Mostaza JM,Lahoz C

    更新日期:2014-04-07 00:00:00

  • The role of the national general medical journal: surveys of which journals UK clinicians read to inform their clinical practice.

    abstract:BACKGROUND:For biomedical research findings to contribute toward health gains they must reach clinicians. Academic journals have historically been considered important information sources. Birken and Parkin found seven journals to most consistently contain the best pediatric evidence and, of these seven, four were gene...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/S0025-7753(08)76404-2

    authors: Jones TH,Hanney S,Buxton MJ

    更新日期:2008-12-01 00:00:00

  • [Evolution of the prevalence of HIV-1 infection in drug addicts in the Community of Madrid (1985-1986)].

    abstract:BACKGROUND:To evaluate the evolution of the HIV infection in the drug addicts of Madrid. PATIENTS AND METHODS:Data of 2,234 patients that entered for the first time in a Psychiatric Hospital Detoxication Unit of Madrid from October 1985 to december 1996 were recorded. RESULTS:There was a reduction of the percentage o...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Sopelana P,Carrascosa C,García-Benito P

    更新日期:1998-09-12 00:00:00

  • [Urinary tract infection in postmenopausal diabetic women. Clinical survey of hospital and nonhospital populations (author's transl)].

    abstract::The incidence and clinical course of urinary tract infections in postmenopausal diabetic patients in comparison to non-diabetic women have been evaluated. All cases with former history of urinary instrumentation or underlying conditions favoring urinary infections were rejected. Urinary tract infection was present in ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Torres Martí A,Jordá R,Vernet M,Cano JF,Coll J,Vivancos J,Balcells A

    更新日期:1980-10-10 00:00:00

  • [Chronic hepatitis E].

    abstract::The hepatitis E virus is an RNA virus with 4 genotypes. Genotypes 1 and 2 only affect humans and produce epidemic acute hepatitis in endemic regions (Asia and Africa). Genotypes 3 and 4 are considered a zoonosis and produce episodic acute hepatitis in non-endemic areas (America and Europe). However, in the last 3 year...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2011.02.003

    authors: González Tallón AI,Moreira Vicente V,Mateos Lindemann ML

    更新日期:2012-02-04 00:00:00

  • [Comparative study of three selective methods for nosocomial pneumonia surveillance in non-critical adult patients].

    abstract:BACKGROUND AND OBJECTIVE:Among nosocomial infections, pneumonia is one of the most important ones due to the mortality, morbidity and the increase of costs that it causes. The implementation of a cost-effective surveillance system for these infections is a challenge for hospitals. The objective of this work was to eval...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13070453

    authors: Bautista Rentero D,Giménez Ferri JL,Zanón Viguer V

    更新日期:2005-01-22 00:00:00

  • [Optic neuritis, brain stem syndromes and myelitis: rapid conversion to multiple sclerosis].

    abstract:BACKGROUND:To establish the early risk of multiple sclerosis (MS) following isolated demyelinating syndromes. PATIENTS AND METHOD:36 patients with optic neuritis, 24 with brainstem syndromes, 27 with spinal cord syndromes and 8 patients with a poliregional syndrome were included in a prospective protocol: including cl...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Tintoré M,Rovira A,Hernández D,Río J,Marzo ME,Montalban X

    更新日期:1999-05-22 00:00:00

  • [Validation and comparison of four instruments to detect partner violence in health-care setting].

    abstract:BACKGROUND AND OBJECTIVES:To validate four instruments to detect domestic violence in health-care settings against external criteria -Index of Spouse Abuse (ISA), Psychological Maltreatment of Women Inventory short form (PMWI-SF), Woman Abuse Screening Tool (WAST), Partner Violence Screen (PVS)- and to assess the conco...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2010.11.038

    authors: Garcia-Esteve L,Torres A,Navarro P,Ascaso C,Imaz ML,Herreras Z,Valdés M

    更新日期:2011-10-08 00:00:00

  • [Mortality caused by cardiovascular diseases in Spain: where are we going?].

    abstract::Spain is one of the european countries with a lowest mortality rate by cardiovascular diseases (although they are the leading cause of mortality) and, specifically, by ischemic heart disease. The trends in the last 16 years for which data are available point to a reduction of the former in 1.07% in males and 1.53% in ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Banegas Banegas JR,Rodríguez Pérez P,Rodríguez Artalejo F,Martín Moreno JM,González Enríquez J

    更新日期:1989-10-28 00:00:00

  • [Differences between office and ambulatory control of hypertension in very elderly patients. The CARDIORISC - MAPAPRES project].

    abstract:BACKGROUND AND OBJECTIVE:Hypertension is highly prevalent in the very elderly. We studied control rates of hypertension according to clinic blood pressure (BP) and ambulatory BP monitoring (ABPM) in treated hypertensives aged > or =80 years. PATIENTS AND METHOD:Data came from the Spanish Society of Hypertension ABPM R...

    journal_title:Medicina clinica

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.medcli.2009.04.056

    authors: Llisterri JL,Alonso FJ,Gorostidi M,Sierra C,de La Sierra A,Banegas JR,Segura J,Sobrino J,De La Cruz JJ,Madruga F,Aranda P,Redon J,Ruilope LM,en representación de los investigadores del Proyecto CARDIORISC-MAPAPRES. Sociedad Esp

    更新日期:2009-11-28 00:00:00

  • [Clinico-hemodynamic study and treatment of 44 patients with primary pulmonary hypertension].

    abstract:BACKGROUND:Primary pulmonary hypertension is a poorly understood disease with a difficult treatment. PATIENTS AND METHOD:Retrospective study of a series of 44 patients suffering from pulmonary hypertension who were studied in our center between 1992 and 2000. RESULTS:At diagnosis, 6 (13%) patients were classified as ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(02)72524-4

    authors: Roman A,Rodés-Cabau J,Lara B,Bravo C,Monforte V,Pallissa E,Domingo E,Morell F

    更新日期:2002-06-01 00:00:00

  • [The usefulness of the teriparatide acetate (Parathar) infusion test in the diagnosis of pseudohypoparathyroidism].

    abstract::In pseudohypoparathyroidism there is a resistance to the action of the parathormone in its target organs. Patients with this disease show clinical and laboratory data of hypoparathyroidism with normal or high levels of parathormone. Three types of pseudohypoparathyroidism are known according to the site in which the d...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Rius F,Salinas I,Reverter JL,Pizarro E,Lucas A

    更新日期:1993-09-18 00:00:00

  • [Perception of safety culture in Spanish intensive care units].

    abstract:BACKGROUND AND OBJECTIVE:Promoting a safety culture in intensive care units (ICUs) is a basic strategy to improve patient safety. The aim of this study was to measure the safety culture in Spanish ICUs. METHOD:We drafted a questionnaire based on the Safety Climate Survey (SCS) and the Safety Attitude Questionnaire-ICU...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/S0025-7753(10)70019-1

    authors: Gutiérrez-Cía I,de Cos PM,Juan AY,Obón-Azuara B,Alonso-Ovies Á,Martin-Delgado MC,Álvarez-Rodríguez J,Aibar-Remón C

    更新日期:2010-07-01 00:00:00

  • [Celiac disease with occipital calcifications: 2 late cases].

    abstract::The association of celiac disease, epilepsy and occipital calcifications with initial clinical manifestations of epilepsy during the first two decades of life with an often progressive and variable course and clinical expression of malabsorption has recently been described. Two cases of celiac disease with occipital c...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Baquero M,Narciso ML,García M,Perla C,Domínguez F

    更新日期:1995-12-08 00:00:00

  • [Spinal cord compression in non-Hodgkin's lymphoma. A study of 10 patients].

    abstract::Spinal cord compression is an infrequent event in patients with non-Hodgkin's lymphomas (NHL) and early diagnosis and therapy are required. The main clinical and histologic characteristics as well as the response to therapy in 10 NHL patients with spinal cord compression diagnosed at a single center in a 7-year period...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Vela D,Ribera JM,Florensa R,Arellano A,Vaquero M,Batlle M,Flores A,Millá F,Feliu E

    更新日期:1997-09-27 00:00:00

  • [Factors associated to aspirin failure for secondary stroke prevention].

    abstract:BACKGROUND:It is not settled whether aspirin (ASA) failure may be predicted in stroke and transient ischemic attack (TIA) patients. The risk of ASA failure may be predicted by analyzing the epidemiological traits of patients with stroke or TIA. PATIENTS AND METHODS:We evaluated retrospectively 695 stroke or TIA patien...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Chamorro A,Blanc R,Ascaso C,Saiz A,Vila N

    更新日期:1997-11-01 00:00:00

  • [Detection of hepatitis B virus DNA in serum by gene amplification in patients with chronic hepatitis B and in patients chronic hepatitis C].

    abstract:BACKGROUND:The polymerase chain reaction (PCR) constitutes important methodological progress for detecting the presence of viral nucleic acids when these are found in small quantities in serum or tissues. The aim of this study was the use of PCR to detect DNA of the hepatitis B virus (HBV) in patients with chronic HBsA...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Jáuregui JI,Civeira MP,Serrano M,Camps J,Castilla A,Riezu-Boj JI,Prieto J

    更新日期:1992-01-18 00:00:00

  • [Effect of tobacco smoking on leptin serum levels and its relationship with steroid hormones and bone mineral density].

    abstract:BACKGROUND AND OBJECTIVE:Leptin is an hormone resulting from the obesity gene. Their actions could be important in the pathogenesis of the osteoporosis. The aim of this study is to analyse the influence of tobacco on serum leptin levels, and its relationship with bone mineral density (BMD) and steroid hormones. SUBJEC...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13094819

    authors: Supervía A,Enjuanes A,Vila J,Mellibovsky L,Nogués X,Díez-Pérez A

    更新日期:2006-11-04 00:00:00

  • [An analysis of the cardiovascular maneuvers for the diagnosis of cardiovascular autonomic neuropathy].

    abstract::Fifteen reflex tests for the diagnosis of cardiovascular autonomic neuropathy (CAN) were evaluated in 90 controls and 154 diabetic patients. We found that age, baseline heart rate and body position differently influenced the tests. The best parasympathetic indexes were Valsalva, inspiration minus expiration (I-E) and ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Sánchez Luis A,Vázquez García JA

    更新日期:1990-09-29 00:00:00

  • [Health in all policies and intersectoriality in health promotion: the Public Health Interdepartmental Plan of Catalonia].

    abstract::In February 2014, the autonomous government in Catalonia, the Generalitat de Catalunya, approved the Catalan Public Health System Interdepartmental Plan (PINSAP, as per the Catalan acronym), responsible for the strategy in Catalonia for Health in All Policies, as recommended by the WHO and other international institut...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/S0025-7753(15)30036-1

    authors: Mateu i Serra A

    更新日期:2015-11-01 00:00:00

  • [Usefulness of polymerase chain reaction for the diagnosis of Bazin erythema induratum].

    abstract:BACKGROUND:Erythema induratum of Bazin (BEI), is included in the group of cutaneous granulomatous lobulillar panniculitis. The aethiopathogenic association between EI and tuberculosis can not rely on the clinicohistological features of these panniculitis and M. tuberculosis has never been isolated from BEI lesions. Det...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Margall N,Baselga E,Coll P,Barnadas M,Sánchez F,de Moragas JM,Prats G

    更新日期:1996-11-30 00:00:00

  • [Bronchiectasis in the elderly. Study of serum levels of immunoglobulin G subclasses].

    abstract:BACKGROUND AND OBJECTIVE:To analyze the serum levels of immunoglobulin G (IgG) subclasses in a broad range of elderly patients with bronchiectasis. PATIENTS AND METHOD:Data were collected from all patients who had a high-resolution chest computerized axial tomography diagnosis of bronchiectasis in our center. We gathe...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13111419

    authors: Martínez-García MA,Román-Sánchez P,Perpiñá-Tordera M,Soler-Cataluña JJ,Saura-Vinuesa A,Yago M,Pastor MJ

    更新日期:2007-10-20 00:00:00

  • [Clinical and epidemiological features of imported dengue in Spain].

    abstract:BACKGROUND AND OBJECTIVE:Dengue is the most common imported arbovirus infection in Europe. International travel and an increasing incidence of dengue fever in tropical areas have defined the disease as an emerging infection in returning travellers. We describe the clinical and microbiological features of imported dengu...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13123037

    authors: Muñoz J,Puente S,López-Vélez R,Domingo C,Ruiz J,Ramírez G,Navarro M,de Orye F,Sanz S,Rivas P,Turrientes MC,Tenorio A,Gascon J

    更新日期:2008-06-07 00:00:00

  • [Current controversies in glycemic control targets. What do the results of the latest clinical trials tell us about the approach to type 2 diabetes mellitus?].

    abstract::The aim of this article is to discuss the implications of the results obtained in the latest large-scale clinical trials designed to evaluate the effect of intensive glycemic control on the vascular complications associated with type 2 diabetes mellitus. The current scientific evidence is reviewed and the implications...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/S0025-7753(10)70025-7

    authors: Mauricio D,Rius F

    更新日期:2010-09-01 00:00:00

  • [Evaluation of ceftazidime monotherapy in Pseudomonas aeruginosa bacteremias. Prospective study].

    abstract::Twenty-six episodes of Pseudomonas aeruginosa bacteremia treated with intravenous ceftazidime, 4-6 g/day were evaluated. Treatment was begun within the first 24 hours after the isolation of the microorganism and was maintained for 10-12 days. In two patients with neutropenia amikacin was added during the initial 48-72...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Gómez J,Moldenhauer F,Ruiz J,Redondo C,Alonso JM,Canteras M,Sánchez-Gascón F

    更新日期:1989-09-16 00:00:00

  • [Hemolytic anemia due to cold-reacting antibodies: association with human immunodeficiency virus infection and non-Hodgkin's lymphoma].

    abstract::Hemolytic disease by cold-reacting antibodies is a rare form of hemolytic anemia. In most cases a subjacent cause is found. This disease is generally related with reactive lymphoproliferative processes (infections by the Epstein-Barr virus and cytomegalovirus) or uncontrolled lymphoproliferative disorders (lymphomas, ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: López Dupla JM,Rodríguez Pérez A,Martínez Martínez P,de Castro Carpeño J,Lavilla Uriol P,Gil Aguado A

    更新日期:1992-04-04 00:00:00

  • [Diagnostic concordance between emergency room and hospitalization in medical patients].

    abstract:BACKGROUND:The purpose of this study was to know the concordance of diagnosis between emergency rooms amd hospitalization wards and to analyze the mistake index, the epidemiological characteristics and the main reasons for the mistakes. PATIENTS AND METHOD:We analyzed hospitalized patients and used a three-level conco...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(02)73485-4

    authors: Tudela P,Mòdol JM,Veny A,Tor J,Bonet M,Rego MJ

    更新日期:2002-10-26 00:00:00

  • [Food consumption, dietary habits and nutritional status of the population of Reus: follow-up from preconception throughout pregnancy and after birth].

    abstract:BACKGROUND AND OBJECTIVE:To describe the evolution of food, energy and nutritional consumption at preconception, weeks 6, 10, 26 and 38 of pregnancy, and 6 and 26 weeks after birth. SUBJECTS AND METHOD:Longitudinal evaluation of the nutritional status in 80 healthy volunteers with the intention of immediate conception...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(04)74395-x

    authors: Arija V,Cucó G,Vila J,Iranzo R,Fernández-Ballart J

    更新日期:2004-06-05 00:00:00

  • [Effects of simvastatin on acute-phase protein levels after cardiac surgery].

    abstract:BACKGROUND AND OBJECTIVE:There is contradictory evidence as to whether the pleiotropic effects of statins improve morbidity/mortality rates in coronary artery bypass grafting with extracorporeal circulation, as they reduce the protein plasma levels in the acute phase. PATIENTS AND METHOD:This randomized prospective st...

    journal_title:Medicina clinica

    pub_type: 杂志文章,随机对照试验

    doi:10.1157/13121102

    authors: Tamayo E,Alonso O,Alvarez FJ,Castrodeza J,Flórez S,di Stefano S

    更新日期:2008-05-31 00:00:00

  • Usefulness of bronchoalveolar lavage and flow cytometry in patients with hematological malignancies and respiratory failure.

    abstract:BACKGROUND AND OBJECTIVES:Strategies to improve the efficiency of bronchoalveolar lavage (BAL) are needed. We conducted a study to establish the diagnostic value of BAL in patients with hematological malignancies and pulmonary infiltrates. PATIENTS AND METHODS:The correlation of cytologic and flow cytometric study of ...

    journal_title:Medicina clinica

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.medcli.2016.10.045

    authors: Ferrà C,Xicoy B,Castillo N,Morgades M,Juncà J,Andreo F,Millá F,Feliu E,Ribera JM

    更新日期:2017-04-07 00:00:00