Association of interleukin-8 gene polymorphisms with the risk of hepatocellular carcinoma.

abstract：:Large-scale random cDNA sequencing projects have been started for several organisms and are a valuable tool for the analysis of quantitative and qualitative aspects of gene expression. However, the reliability of the obtained data is limited as most of the clones are only partially analysed on one strand. As a consequ...

journal_title：Molecular biology reports

authors： Braun HP

更新日期：1996-01-01 00:00:00

abstract：:The aim of this study was to explore the association between alpha-thalassemia, fetal hemoglobin, hematological indices, and clinical adverse events in Angolan sickle cell disease pediatric patients. A total of 200 sickle cell disease (SCD) children were sampled in Luanda and Caxito. A venous blood sample was collecte...

journal_title：Molecular biology reports

authors： Santos B,Delgadinho M,Ferreira J,Germano I,Miranda A,Arez AP,Faustino P,Brito M

更新日期：2020-07-01 00:00:00

abstract：:It is well known that transcriptionally inactive rRNA genes are correlated with DNA hyper-methylation and histone hypo-methylation and there is clear evidence in humans that DNA and histone modification which alter chromatin structure are related to chromosome fragility. Very little is known about the biological cause...

journal_title：Molecular biology reports

authors： Singh M,Barman AS

更新日期：2013-01-01 00:00:00

abstract：:One mutant transgenic line displaying homeotic conversion of sepals to petals with other phenotypic aberrations was selected and characterized at molecular level. The increased transcript level of gene encoding anthocyanidin synthase and petal specific class B genes, GLOBOSA and DEFECIENS in sepals of mutant line may ...

journal_title：Molecular biology reports

authors： Mahajan M,Yadav SK

更新日期：2014-02-01 00:00:00

abstract：:Among the bacteria groups, most of them are known to be beneficial to human being whereas only a minority is being recognized as harmful. The pathogenicity of bacteria is due, in part, to their rapid adaptation in the presence of selective pressures exerted by the human host. In addition, through their genomes, bacter...

journal_title：Molecular biology reports

authors： Alibayov B,Baba-Moussa L,Sina H,Zdeňková K,Demnerová K

更新日期：2014-08-01 00:00:00

abstract：:Kawasaki disease (KD) is a multi-systemic vasculitis which preferentially affects infants and children. A single nucleotide polymorphism (rs28493229) in the inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) was identified to be associated with the increased risk of KD; however, in more recent studies associations have b...

journal_title：Molecular biology reports

authors： Lou J,Xu S,Zou L,Zhong R,Zhang T,Sun Y,Lu X,Liu L,Li C,Wang L,Xiong G,Wang W,Gong F,Wu J

更新日期：2012-12-01 00:00:00

abstract：:Abiotic stresses such as salinity and drought have adverse effects on plants. In the present study, a Na(+)/H(+) antiporter gene homologue (LfNHX1) has been cloned from a local halophyte grass (Leptochloa fusca). The LfNHX1 cDNA contains an open reading frame of 1,623 bp that encodes a polypeptide chain of 540 amino a...

journal_title：Molecular biology reports

authors： Rauf M,Shahzad K,Ali R,Ahmad M,Habib I,Mansoor S,Berkowitz GA,Saeed NA

更新日期：2014-03-01 00:00:00

abstract：:Vascular endothelial growth factor B (VEGF-B) was reported to be angiogenic, and it was considered as a neuroprotective agent in mouse retinal ganglion cells following optic nerve crush. Thus, it was necessary to investigate whether VEGF-B contributes to the process of retinal and choroidal neovascularization. We aime...

journal_title：Molecular biology reports

authors： Zhang GH,Qin R,Zhang SH,Zhu H

更新日期：2014-02-01 00:00:00

abstract：:We reported earlier about the detection of a chromosomally located arsenic operon (arsRBC) in a gram-negative bacterium Pseudomonas fluorescens strain MSP3, which showed resistance to elevated levels of sodium arsenate and sodium arsenite. The genes for arsenic resistance were cloned into the HindIII site of pBluescri...

journal_title：Molecular biology reports

authors： Prithivirajsingh S,Mishra SK,Mahadevan A

更新日期：2001-01-01 00:00:00

abstract：UNLABELLED:Hepatocellular carcinoma (HCC) is a worldwide neoplasm for which early diagnosis is difficult and the prognosis is usually poor. Overexpression of cyclooxygenase 2 (COX-2) has been suggested to be associated with hepatocarcinogenesis. Although several COX-2 inhibitors have been used in hepatoma therapy, the ...

journal_title：Molecular biology reports

authors： Mohamed FZ,Hussein YM,El-Deen IM,Sabea MS

更新日期：2014-03-01 00:00:00

abstract：:As a kind of binding protein, the type 1 Na(+)/H(+) exchanger (NHE1) is a receptor for the highly pathogenic Avian leukosis viruses-J subgroup (ALV-J) in chicken. In order to investigate the potential effect of chicken NHE1 gene on leukosis, we compared its expression between ALV-J-affected and -unaffected chicken, sc...

journal_title：Molecular biology reports

authors： Chen B,Pan W,Zhang L,Liu J,Ouyang H,Nie Q,Zhang X

更新日期：2014-10-01 00:00:00

abstract：:Plant microRNAs have shown the capacity to regulate mammalian systems. The potential bioactivity of miR171vr, an isoform of the plant miR171, on human embryonic kidney 293 (HEK293) cells was investigated. Bioinformatics simulations revealed that human G protein subunit alpha 12 (GNA12) transcript could represent an ex...

journal_title：Molecular biology reports

authors： Gismondi A,Nanni V,Monteleone V,Colao C,Di Marco G,Canini A

更新日期：2021-01-01 00:00:00

abstract：:Variants of the transcription factor 7-like 2 gene (TCF7L2) have been associated with type 2 diabetes and cardiovascular disease in different populations. Here we investigated the potential association of the rs7903146 polymorphism in the TCF7L2 gene with clinical profile of end-stage renal disease (ESRD) patients. We...

journal_title：Molecular biology reports

authors： Buraczynska M,Zukowski P,Ksiazek P,Kuczmaszewska A,Janicka J,Zaluska W

更新日期：2014-06-01 00:00:00

abstract：:Recent studies suggest that the common variant in the GSTM1 and GSTT1 genes modifies the risk of coronary artery disease (CAD), however, it is unclear whether the risk of CAD modulated by variants in the GSTM1 and GSTT1 genes was associated with alterations of indices of oxidative stress and inflammation. Our study is...

journal_title：Molecular biology reports

authors： Tang JJ,Wang MW,Jia EZ,Yan JJ,Wang QM,Zhu J,Yang ZJ,Lu X,Wang LS

更新日期：2010-01-01 00:00:00

abstract：:Biochemical networks comprise many diverse components and interactions between them. It has intracellular signaling, metabolic and gene regulatory pathways which are highly integrated and whose responses are elicited by extracellular actions. Previous modeling techniques mostly consider each pathway independently with...

journal_title：Molecular biology reports

authors： Tomar N,Choudhury O,Chakrabarty A,De RK

更新日期：2013-02-01 00:00:00

abstract：:Phosphomannose isomerase (PMI) is an enzyme that catalyses the first step of the L-galactose pathway for ascorbic acid (AsA) biosynthesis in plants. To clarify the physiological roles of PMI in AsA biosynthesis, the cDNA sequence of PMI was cloned from non-heading Chinese cabbage (Brassica campestris ssp. chinensis Ma...

journal_title：Molecular biology reports

authors： Wang X,Zhang S,Hu D,Zhao X,Li Y,Liu T,Wang J,Hou X,Li Y

更新日期：2014-01-01 00:00:00

abstract：:Common bean is gaining acceptance as one of the most valuable major food consumed worldwide owing to innumerable nutritional and therapeutic benefits. Comparatively less productivity in underdeveloped countries encouraged us to proceed for QTL mining of yield traits in common bean. Heretofore, multiple yield associate...

journal_title：Molecular biology reports

authors： Gupta N,Zargar SM,Singh R,Nazir M,Mahajan R,Salgotra RK

更新日期：2020-09-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) incidence is fast-growing especially in countries highly prevalent with viral hepatitis. Its poor prognosis has driven the research toward the discovery of sensitive markers for early detection. We investigated the usefulness of serum Transforming growth factor-beta1 (TGF-β1), Glypican-3...

journal_title：Molecular biology reports

authors： Ibrahim GH,Mahmoud MA,Aly NM

更新日期：2013-12-01 00:00:00

abstract：:In individuals with diabetes, a log linear relationship exists between cholesterol levels and cardiovascular disease. Type 2 diabetes (T2D) and Statins, a cholesterol lowering drug, have a complex relationship. Statins are potent modulators of CYP3A4 2 enzyme and endothelial nitric oxide synthase (eNOS) functions in a...

journal_title：Molecular biology reports

authors： Jamil K,Kandula V,Kandula R,Asimuddin M,Joshi S,Yerra SK

更新日期：2014-10-01 00:00:00

abstract：:In higher eukaryotes mechanism of DNA replication origin recognition and binding by origin recognition complex (ORC) is still unknown. Origin transfer studies have shown that origin sites are genetically determined, containing functionally interchangeable modules. One of such modules from the human lamin B2 origin of ...

journal_title：Molecular biology reports

authors： Kusic J,Tomic B,Divac A,Kojic S

更新日期：2010-06-01 00:00:00

abstract：:Single nucleotide polymorphisms (SNPs) in adiponectin gene [rs1501299 (+276G/T) and rs266729 (-11377C/G)] and one SNP of leptin gene [rs7799039 (-2548G/A)] are known to influence plasma levels of adiponectin and leptin respectively. Literature is scarce on the association of adiponectin gene polymorphism rs266729 with...

journal_title：Molecular biology reports

authors： Geriki S,Bitla AR,SrinivasaRao PVLN,Hulikal N,Yootla M,Sachan A,Amancharla Yadagiri L,Asha T,Manickavasagam M,Kannan T,Kumari AP

更新日期：2019-12-01 00:00:00

abstract：:Staudtia kamerunensis (Myristicaceae) or 'Niové' is an evergreen tree widespread in Central African moist forests. The bark and seeds are used in traditional medicine, yet the tree is mainly harvested for its high quality, multi-purpose timber. To facilitate sustainable harvesting and conservation of the species, we a...

journal_title：Molecular biology reports

authors： Vanden Abeele S,Hardy OJ,Janssens SB

更新日期：2018-10-01 00:00:00

abstract：:Cotton fiber cells elongate without dividing to form economically valuable spinnable fiber. Reports of the ploidy level of fiber cells are variable. Early reports indicated an increase in nuclear DNA content in young fibers; however, subsequent reports failed to observe such a significant increase in ploidy level. Eva...

journal_title：Molecular biology reports

authors： Taliercio E,Ray J,Scheffler J

更新日期：2010-02-01 00:00:00

abstract：:Nowadays, lower post-release survivorship of hatchery-reared fish in natural aquatic bodies has attained great attention and research is in progress to determine the reasons for their higher mortality. It is assumed that hatchery rearing environments negatively affect the physiological stress response of the fish. Thu...

journal_title：Molecular biology reports

authors： Murtaza MUH,Zuberi A,Ahmad M,Amir I,Kamran M,Ahmad M

更新日期：2020-07-01 00:00:00

abstract：:Cell-based approaches offer a potential therapeutic strategy for appropriate bone manufacturing. Capable of differentiating into multiple cell types especially osteoblasts spontaneously, unrestricted somatic stem cell (USSC) seems to be a suitable candidate. Recent studies have shown the involvement of microRNAs in se...

journal_title：Molecular biology reports

authors： Bakhshandeh B,Soleimani M,Hafizi M,Paylakhi SH,Ghaemi N

更新日期：2012-07-01 00:00:00

abstract：:Spermiogenesis is a developmental process undergoing continuous differentiation to drive a diploid spermatogonium towards a haploid sperm cell. This striking transformation from spermatogonium to spermatozoa is made possible by the stage-specific adaption of cytoskeleton and associated molecular motor proteins. KIFC1 ...

journal_title：Molecular biology reports

authors： Wang YT,Mao H,Hou CC,Sun X,Wang DH,Zhou H,Yang WX

更新日期：2012-07-01 00:00:00

abstract：:The beta class of the carbonic anhydrase (CA) enzyme family has been found in plants, yeast, bacteria and algae, but not in animals. Also, little is known concerning the CAs of C. elegans. Genes possibly encoding beta-CAs were revealed by in silico analysis of the C. elegans genome. Amino acid sequence and 3D structur...

journal_title：Molecular biology reports

authors： Fasseas MK,Tsikou D,Flemetakis E,Katinakis P

更新日期：2010-07-01 00:00:00

abstract：:The transforming growth factor-β (TGF-β) signaling pathway is conserved across animals, and knowledge of its roles during the molt cycle in crustaceans is presently very limited. This study investigates the roles of the TGF-β receptor in molting-related muscle growth in Eriocheir sinensis. Using the RT-PCR and RACE te...

journal_title：Molecular biology reports

authors： Tian Z,Peng H,Deng W,Jiao C

更新日期：2020-01-01 00:00:00

abstract：:Tetrahydrobiopterin (BH4) is an essential cofactor for aromatic acid hydroxylases, which control the levels of monoamine neurotransmitters. BH4 deficiency has been associated with many neuropsychological disorders. Dihydrofolate reductase (DHFR) can catalyze 7,8-dihydrobiopterin to 5,6,7,8-tetrahydrobiopterin (BH4) in...

journal_title：Molecular biology reports

authors： Wang W,Gao J,Wang J,Liu C,Meng Y

更新日期：2012-12-01 00:00:00

abstract：:The CRISPR/Cas9 system now allows for unprecedented possibilities of genome editing. However, there are some limitations, including achieving efficient one-step multiple genome targeting to save costs, time, and ensure high quality. In the present study, we investigated the efficiency of one-step multiple gene modific...

journal_title：Molecular biology reports

authors： Hirata M,Wittayarat M,Namula Z,Le QA,Lin Q,Nguyen NT,Takebayashi K,Sato Y,Tanihara F,Otoi T

更新日期：2020-07-01 00:00:00