Human initiation protein Orc4 prefers triple stranded DNA.

abstract：:In jasmonate biosynthetic pathway, allene oxide synthase (AOS, EC 4.2.1.92), which is a cytochrome P450 (CYP74A), catalyzes the first committed step. We herein cloned a novel cDNA from Lonicera japonica Thunb., named LjAOS (GenBank accession: DQ303120), which was homologous to other AOSs. Southern blot analysis reveal...

journal_title：Molecular biology reports

authors： Jiang K,Pi Y,Hou R,Zeng H,Huang Z,Zhang Z,Sun X,Tang K

更新日期：2009-03-01 00:00:00

abstract：:STAT4 is a transcription factor that has been implicated in the pathogenesis of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Recently, several reports has documented that a STAT4 haplotype is associated with RA, SLE and Sjogren's syndrome. To summarize and review these findings, we conducted a met...

journal_title：Molecular biology reports

authors： Ji JD,Lee WJ,Kong KA,Woo JH,Choi SJ,Lee YH,Song GG

更新日期：2010-01-01 00:00:00

abstract：:CD40 signaling plays a critical role in the survival rate of gastric cancer patients. Tumour samples were collected from 73 patients with who were diagnosed as gastric cancer in general surgery department in the 1st affiliated hospital of Suzhou University between September 2002 and July 2003. All patients had not rec...

journal_title：Molecular biology reports

authors： Li R,Chen WC,Pang XQ,Tian WY,Wang WP,Zhang XG

更新日期：2012-09-01 00:00:00

abstract：:The swine fatty acid binding protein gene (FABP3) has been screened with 4 primer sets for 270 purebred Yorkshire pigs from National Institute of Animal Science. The selection of primers was based on the swine cDNA sequence (AJ416019), and primer sets (FABP3-2 and FABP3-3) amplified target segments in real time PCR to...

journal_title：Molecular biology reports

authors： Cho KH,Kim MJ,Jeon GJ,Chung HY

更新日期：2011-03-01 00:00:00

abstract：:The purpose of this study was to investigate the efficacy of Endostar combined with chemotherapy on human esophageal squamous cell carcinoma Eca-109 in mice. The tumor xenograft models were established and randomly assigned to 4 groups: control group, Endostar group (1.5 mg/kg day, once daily for 3 weeks), chemotherap...

journal_title：Molecular biology reports

authors： Chang L,Guo F,Lv Y,Wang Y,Huo B,Wang L,Liu W

更新日期：2013-01-01 00:00:00

abstract：:The interleukin (IL)-1β-511 C/T polymorphism has been shown to be functional and to contribute to the risk of gastric cancer. However, the relationship between the IL-1β-511 C/T polymorphism and gastric carcinogenesis remains inconclusive. A systematical electronic search was conducted of the MEDLINE, EMBASE, and CENT...

journal_title：Molecular biology reports

authors： Park MJ,Hyun MH,Yang JP,Yoon JM,Park S

更新日期：2015-01-01 00:00:00

abstract：:Growth-regulating factor (GRF) is an important protein in GA-mediated response, with key roles in plant growth and development. However, it is not known whether or how the GRF proteins in citrus to regulate organ size. In this study, nine citrus GRF genes (CsGRF1-9) were validated from the 'Anliu' sweet orange (AL, Ci...

journal_title：Molecular biology reports

authors： Liu X,Guo LX,Jin LF,Liu YZ,Liu T,Fan YH,Peng SA

更新日期：2016-10-01 00:00:00

abstract：:Sheep are valuable resources for the wool industry. Wool growth of Aohan fine wool sheep has cycled during different seasons in 1 year. Therefore, identifying genes that control wool growth cycling might lead to ways for improving the quality and yield of fine wool. In this study, we employed Agilent sheep gene expres...

journal_title：Molecular biology reports

authors： Liu N,Li H,Liu K,Yu J,Cheng M,De W,Liu J,Shi S,He Y,Zhao J

更新日期：2014-08-01 00:00:00

abstract：:Endometriosis is a polygenic and multifactorial gynecology situation which might be associated with angiogenesis. In the current study we assess the role of vascular endothelial growth factor (VEGF) - 2578 A/C, and + 936 C/T polymorphisms in susceptibility to endometriosis and checking the expression of VEGF mRNA in e...

journal_title：Molecular biology reports

authors： Rashidi BH,Sarhangi N,Aminimoghaddam S,Haghollahi F,Naji T,Amoli MM,Shahrabi-Farahani M

更新日期：2019-06-01 00:00:00

abstract：:Vascular endothelial growth factor B (VEGF-B) was reported to be angiogenic, and it was considered as a neuroprotective agent in mouse retinal ganglion cells following optic nerve crush. Thus, it was necessary to investigate whether VEGF-B contributes to the process of retinal and choroidal neovascularization. We aime...

journal_title：Molecular biology reports

authors： Zhang GH,Qin R,Zhang SH,Zhu H

更新日期：2014-02-01 00:00:00

abstract：:The ATP-binding cassette transporter ABCG2 (also known as breast cancer resistance protein, BCRP) belongs to the ATP-binding cassette (ABC) family of transmembrane drug transporters, playing a crucial role in the protection of various cells and tissues against xenotoxins and/or endotoxins. Recently, several studies ha...

journal_title：Molecular biology reports

authors： Yue W,Fang X,Zhang C,Pang Y,Xu H,Gu C,Shao R,Lei C,Chen H

更新日期：2011-06-01 00:00:00

abstract：:This novel orange fluorescent protein (OFP) emits brilliant orange fluorescent light. OFP has high fluorescence quantum yield, fast maturation rate, and stability, which imply this protein should be the most favorable biotechnological tools used to investigate the function of target gene by visualizing, monitoring, an...

journal_title：Molecular biology reports

authors： Liu JM,David WC,Ip DT,Li XH,Li GL,Wu XF,Yue WF,Zhang CX,Miao YG

更新日期：2009-02-01 00:00:00

abstract：:ColE1 DNA replication is initiated by RNA II and inhibited by RNA I. Control of the replication occurs through the interaction between RNA I and RNA II. Therefore, RNases involved in the metabolism of RNA I and RNA II are expected to play a key role in the control of the ColE1 plasmid replication. RNase H, RNase E, RN...

journal_title：Molecular biology reports

authors： Jung YH,Lee Y

更新日期：1995-01-01 00:00:00

abstract：:An RNA polymerase III transcript, 7SK nuclear RNA, was found to bear sequence homology to the B2 class of highly repeated elements in the mouse genome. Northern blot hybridizations between the small RNAs and two B2 clones showed that only one of them (p49C8) hybridized to 7SK RNA. Both clones, however, hybridized to 4...

journal_title：Molecular biology reports

authors： Gallant J,Lovely J,Krause M

更新日期：1987-01-01 00:00:00

abstract：:In the present study, Amukkara Chooram (AC) a well known herbal medicine was investigated for their antibiofilm efficacy against biofilm of Candida albicans. The biofilm inhibitory concentration of 20 µg/mL of AC showed promising effect by inhibiting the biofilm upto 60%. Morphogenic transition state of C. albicans fr...

journal_title：Molecular biology reports

authors： Rajamohamed BS,Siddharthan S

更新日期：2019-06-01 00:00:00

abstract：:The aim of this study was to explore the association between alpha-thalassemia, fetal hemoglobin, hematological indices, and clinical adverse events in Angolan sickle cell disease pediatric patients. A total of 200 sickle cell disease (SCD) children were sampled in Luanda and Caxito. A venous blood sample was collecte...

journal_title：Molecular biology reports

authors： Santos B,Delgadinho M,Ferreira J,Germano I,Miranda A,Arez AP,Faustino P,Brito M

更新日期：2020-07-01 00:00:00

abstract：:The complete mitochondrial genome of Zhikong scallop Chlamys farreri is 21,695 bp in length and contains 12 protein-coding genes (the atp8 gene is absent, as in most bivalves), 2 ribosomal RNA genes, and 22 transfer RNA genes. The heavy strand has an overall A+T content of 58.7%. GC and AT skews for the mt genome of C...

journal_title：Molecular biology reports

authors： Xu K,Kanno M,Yu H,Li Q,Kijima A

更新日期：2011-06-01 00:00:00

abstract：:Schistosomiasis, a disease caused by helminth parasites of genus Schistosoma. Its treatment intensively depends on single drug, praziquantel which increases the risk of development of drug-resistant parasite. Inhibitors of human HDAC are profoundly reported as novel anti-cancer drugs and used as new anit-parasitic age...

journal_title：Molecular biology reports

authors： Singh R,Pandey PN

更新日期：2015-03-01 00:00:00

abstract：:Hepatitis C virus (HCV) can be classified into six major genotypes. The HCV genotypes variability accounts for its geographical distribution, its responses to treatments and the clinical outcomes. The aim of this study was to determine the distribution of HCV genotypes among volunteer blood donors in Thailand. Samples...

journal_title：Molecular biology reports

authors： Sistayanarain A,Kunthalert D,Vipsoongnern Y

更新日期：2011-10-01 00:00:00

abstract：:Interleukin-8 (IL8) polymorphisms have been implicated in several cancers, but their roles in the pathogenesis of hepatocellular carcinoma (HCC) are largely unknown. The present study was designed to explore the association between IL8 polymorphism and the risk of HCC in a Chinese population. Four single nucleotide po...

journal_title：Molecular biology reports

authors： Wang JL,Nong LG,Wei YS,Tang YJ,Wang JC,Wang CF

更新日期：2014-03-01 00:00:00

abstract：:This study was designed to examine the interactions of ergosterol with bovine serum albumin (BSA) and human serum albumin (HSA) under physiological conditions with the drug concentrations in the range of 2.99-105.88 μM and the concentration of proteins was fixed at 5.0 μM. The analysis of emission spectra quenching at...

journal_title：Molecular biology reports

authors： Cheng Z

更新日期：2012-10-01 00:00:00

abstract：:Dengue virus and Zika virus are arthropod-borne flaviviruses that cause millions of infections worldwide. The co-circulation of both viruses makes serological diagnosis difficult as they share high amino acid similarities in viral proteins. Antigens are one of the key reagents in the differential diagnosis of these vi...

journal_title：Molecular biology reports

authors： Lopes-Luz L,Junqueira IC,da Silveira LA,de Melo Pereira BR,da Silva LA,Ribeiro BM,Nagata T

更新日期：2020-10-01 00:00:00

abstract：:Type 2 diabetes is one of the most prevalent diseases, which increases resistance to insulin in target tissues. The measurement of miRNAs quantity is a molecular approach for diagnosis of diabetes. miRNAs are small non-coding RNA strings of 21-23 long nucleotides that act as inhibitors in proteins translation. Several...

journal_title：Molecular biology reports

authors： Andoorfar S,Hosseini Tafreshi SA,Rezvani Z

更新日期：2019-10-01 00:00:00

abstract：:Induction and break of bud dormancy are important features for perennial plants surviving extreme seasonal variations in climate. However, the molecular mechanism of the dormancy regulation, still remain poorly understood. To better understand the molecular basis of poplar bud dormancy, we used a label-free quantitati...

journal_title：Molecular biology reports

authors： Ning DL,Liu CC,Liu JW,Shen Z,Chen S,Liu F,Wang BC,Yang CP

更新日期：2013-07-01 00:00:00

abstract：:The Italian National Reference Center for Echinococcosis (CeNRE, Sassari, Italy) set up a diagnostic protocol of "one-step-PCR" useful for the detection of E. granulosus sensu stricto (E.g.s.s.) and the identification of its genotype (G1-G3). The purpose of this work was to perform the validation of the "PCR E.g.s.s."...

journal_title：Molecular biology reports

authors： Santucciu C,Masu G,Mura A,Peruzzu A,Piseddu T,Bonelli P,Masala G

更新日期：2019-04-01 00:00:00

abstract：:High Mobility Group Box 1 (HMGB1) is a nuclear protein participating in chromatin architecture and transcriptional regulation. Recently, there is increasing evidence that HMGB1 contributes to the pathogenesis of chronic inflammatory and autoimmune diseases due to its pro-inflammatory and immunostimulatory properties. ...

journal_title：Molecular biology reports

authors： Pan HF,Wu GC,Li WP,Li XP,Ye DQ

更新日期：2010-03-01 00:00:00

abstract：:Brassica oleracea var. capitata (cabbage) is an economically important crop affected by black rot disease caused by Xanthomonas campestris pv. campestris (Xcc). MicroRNAs (miRNAs) play an important role in plant defense modulation and therefore the analysis of these molecules can help better understand plant-pathogen ...

journal_title：Molecular biology reports

authors： Santos LS,Maximiano MR,Megias E,Pappas M,Ribeiro SG,Mehta A

更新日期：2019-06-01 00:00:00

abstract：:The purpose of this study was to assess the value of cytokeratin 19 (CK19) and matrix metalloproteinase 2 (MMP-2) in predicting lymph node metastasis (LNM) and survival after curative resection in hepatocellular carcinoma (HCC) patients. Expression of CK19 and MMP-2 in tumor tissue was assessed through immunohistochem...

journal_title：Molecular biology reports

authors： Xiang ZL,Zeng ZC,Tang ZY,Fan J,Sun HC,Tan YS

更新日期：2011-06-01 00:00:00

abstract：:The fat mass and obesity associated gene (FTO) has been widely reported to be associated with fat mass or fat deposition in different species. In the present study, we cloned both promoter and coding regions of the gene in pigs with over 5 Kb of sequence for the former region and 1,596 bp for the latter region. Compar...

journal_title：Molecular biology reports

authors： Huang J,Yang Y,Liu G,Zhang J,Dong X,Bai Y,Fang M

更新日期：2011-04-01 00:00:00

abstract：:Vitiligo is a common chronic depigmented skin disease characterized by melanocyte loss or dysfunction in the lesion. The pathogenesis of vitiligo has not been fully clarified. Most studies have suggested that the occurrence and progression of vitiligo are due to multiple factors and gene interactions in which noncodin...

journal_title：Molecular biology reports

authors： Yan S,Shi J,Sun D,Lyu L

更新日期：2020-04-01 00:00:00