Primary cutaneous anaplastic large-cell lymphoma--case report.

Abstract:

:Primary cutaneous anaplastic large-cell lymphoma is part of the spectrum of CD30+ lymphoproliferative cutaneous processes, characterized by single or multifocal nodules that ulcerate, are autoregressive and recurrent. Extracutaneous dissemination may occur, especially to regional lymph nodes. Histology shows a diffuse, non-epidermotropic infiltrate , anaplastic large lymphoid cells of immunohistochemistry CD30+, CD4+, EMA-/+, ALK-, CD15- and TIA1-/+. Prognosis is good and does not depend on lymphatic invasion. Radiotherapy, removal of the lesion and/or low-dose methotrexate are the treatments of choice. The present study reports the case of a 57-year-old-woman presenting Primary cutaneous anaplastic large-cell lymphoma with multifocal lesions. The patient evolved with pulmonary involvement 7 years later. She showed a good response to the treatment with low-dose methotrexate prescribed weekly.

journal_name

An Bras Dermatol

authors

Oliveira LS,Nobrega MP,Monteiro MG,Almeida WL

doi

10.1590/abd1806-4841.20131731

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

132-5

issue

6 Suppl 1

eissn

0365-0596

issn

1806-4841

pii

S0365-05962013000800132

journal_volume

88

pub_type

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