Recurrent skin ulcer cross-repair and sensory reconstruction in a WRN gene mutational patient.

Abstract:

:A 37-year-old man complained of a refractory posterior malleolar ulceration on his left ankle. He was diagnosed with Werner syndrome according to the progeroid clinical features and genetic testing. To approach the ulceration, a free flow-through right anterolateral thigh perforator flap with anterolateral thigh cutaneous nerve was harvested. One year later, he was readmitted due to a new ulceration on his right ankle. We harvested the left anterolateral thigh perforator flap with anterolateral thigh cutaneous nerve to reconstruct the defect. After one more year of follow-up, there was no recurrence of ulcers, and the sensation of the flap recovered partially after 6 months. We conclude that free flow-through anterolateral thigh perforator flap is a feasible choice for the repair of foot ulcers in Werner syndrome.

journal_name

An Bras Dermatol

authors

He J,Wu P,Pan D,Tang J

doi

10.1590/abd1806-4841.20187517

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

443-446

issue

3

eissn

0365-0596

issn

1806-4841

pii

S0365-0596(20)30454-2

journal_volume

93

pub_type

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