Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients.

Abstract:

:In this review, the most relevant and current epidemiological data, the main clinical, laboratory and therapeutical aspects of leprosy are presented. Detailed discussion of the main drugs used for leprosy treatment, their most relevant adverse effects, evolution of the therapeutic regimen, from dapsone as a monotherapy to the proposed polychemotherapy by World Health Organization (WHO) can be found in this CME. We specifically highlight the drug acceptability, reduction in treatment duration and the most recent proposal of a single therapeutic regimen, with a fixed six months duration, for all clinical presentations, regardless of their classification.

journal_name

An Bras Dermatol

authors

Cruz RCDS,Bührer-Sékula S,Penna MLF,Penna GO,Talhari S

doi

10.1590/abd1806-4841.20176724

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

761-773

issue

6

eissn

0365-0596

issn

1806-4841

pii

S0365-05962017000600761

journal_volume

92

pub_type

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