Abstract:
:In this review, the most relevant and current epidemiological data, the main clinical, laboratory and therapeutical aspects of leprosy are presented. Detailed discussion of the main drugs used for leprosy treatment, their most relevant adverse effects, evolution of the therapeutic regimen, from dapsone as a monotherapy to the proposed polychemotherapy by World Health Organization (WHO) can be found in this CME. We specifically highlight the drug acceptability, reduction in treatment duration and the most recent proposal of a single therapeutic regimen, with a fixed six months duration, for all clinical presentations, regardless of their classification.
journal_name
An Bras Dermatoljournal_title
Anais brasileiros de dermatologiaauthors
Cruz RCDS,Bührer-Sékula S,Penna MLF,Penna GO,Talhari Sdoi
10.1590/abd1806-4841.20176724subject
Has Abstractpub_date
2017-11-01 00:00:00pages
761-773issue
6eissn
0365-0596issn
1806-4841pii
S0365-05962017000600761journal_volume
92pub_type
杂志文章,评审abstract:BACKGROUND:Actinic keratosis (AK) represents a risk of progression to squamous cell carcinoma. Ingenol mebutate gel is a novel therapeutic option for field-directed treatment. OBJECTIVES:To evaluate the safety, tolerability and patients' perspectives, related to the therapeutic success of managing AKs on the face and ...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20197938
更新日期:2019-07-29 00:00:00
abstract:BACKGROUND:Superficial mycoses are fungal infections limited to the outermost layers of the skin. Dermatophytic filamentous fungi and yeasts are the major causative agents of these mycoses. Dermatophytosis is one of the clinical conditions caused by fungal infections most commonly found in dermatological practice. Thus...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20141783
更新日期:2014-01-01 00:00:00
abstract::This report presents the case of a 13-year-old female patient with history of acute myeloid leukemia, who, after a bone marrow transplant, began to vomit and experienced rapidly progressive deterioration of consciousness, in addition to disseminated erythematous-violaceous macules, and some blisters with hemorrhagic c...
journal_title:Anais brasileiros de dermatologia
pub_type:
doi:10.1016/j.abd.2020.03.007
更新日期:2020-01-01 00:00:00
abstract::Ascher's syndrome consists of double lip, blepharochalasis and sometimes non-toxic thyroid enlargement. It is a rare, benign, rarely reported, and sometimes misdiagnosed condition that most often affects patients under 20 years old. The etiology remains unknown, although factors such as trauma, hormonal dysfunction an...
journal_title:Anais brasileiros de dermatologia
pub_type:
doi:10.1590/abd1806-4841.20177158
更新日期:2017-09-01 00:00:00
abstract::Morphometric analysis of dermal collagen can provide quantitative support to dermatologic research. The authors of this article disclose a technique of digital image analysis which allows the identification of microscopic structures by color cluster segmentation regarding the estimate intensity and density of dermal c...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962010000300010
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Pentavalent antimonials remain as the standard drugs in the treatment of cutaneous leishmaniosis. The high cost, difficult administration, long treatment time, toxicity and increasing morbidity are factors that limit the use of these drugs. OBJECTIVES:To describe the response to radiofrequency thermotherapy...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20186415
更新日期:2018-01-01 00:00:00
abstract::Vegetative chronic genital herpes is an atypical presentation of herpes simplex 2 that it is usually seen in patients coinfected with human immunodeficiency virus. Clinically, it is characterized by extensive ulcers that evolve to chronification and hypertrophic pseudotumor forms. Antiviral drugs are recommended for t...
journal_title:Anais brasileiros de dermatologia
pub_type:
doi:10.1590/abd1806-4841.20198014
更新日期:2019-03-01 00:00:00
abstract::Pencil core granulomas are still infrequently reported in the literature. A 67-year-old woman presented with a 4mm hard blue subcutaneous nodule on the forehead. She remembered being injured with a pencil tip about 60 years before. The subcutaneous nodule was excised, which microscopically revealed a foreign body reac...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20176011
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Pityriasis alba affects 1% of the world population and about 9.9% of the children in Brazil. However, its etiology remains uncertain. OBJECTIVE:The objective of the present study was to evaluate the immunoexpression of factor XIIIa in dermal dendrocytes of skin lesions of pityriasis alba. METHOD:Twenty pat...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20142201
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Myeloid leukemia cutis is the terminology used for cutaneous manifestations of myeloid leukemia. OBJECTIVE:The purpose of this study was to study the clinical, histopathological and immunohistochemical features of myeloid leukemia cutis. METHODS:This was a retrospective study of clinical and pathological f...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20186327
更新日期:2018-03-01 00:00:00
abstract::Lipschütz Ulcer, or ulcus vulvae acutum, is a rare and probably underdiagnosed entity that usually presents as an acute painful vulvar ulcer in young women. The etiology is unknown, although recent reports have associated it with the Epstein-Barr virus. The diagnosis is made by exclusion after ruling out sexually tran...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962012000400018
更新日期:2012-07-01 00:00:00
abstract::Dermatophytosis caused by Microsporum gypseum is rare, especially in infants, with few published cases. Diagnosis in this age group is frequently delayed. We review the literature and report 4 new cases of tinea of glabrous skin caused by M. gypseum mimicking eczema in infants. Considering new and previously reported ...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章,评审
doi:10.1590/abd1806-4841.20165044
更新日期:2016-11-01 00:00:00
abstract::Light microscopy of granuloma annulare shows mucin deposition with lympho-histiocytic infiltrate. We describe the ultrastructural three-dimensional aspects of a typical case of granuloma with characteristic histopathological findings. At the ultrastructural level, affected collagen bundles and granular mucin depositio...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20187409
更新日期:2018-09-01 00:00:00
abstract::Chromoblastomycosis is a subcutaneous mycosis caused by the dermatophytic fungi Fonsecaea, Phialophora and Cladophialophora. Usual complications include secondary infection, lymphedema and elephantiasis. Associated malignancies have been found in chronic cases. This case report describes a 72 year-old male with a 30 y...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962010000200025
更新日期:2010-03-01 00:00:00
abstract::The etiology of pityriasis lichenoides is unknown. One of the accepted theories admits that PL is an inflammatory response to extrinsic antigens such as infectious agents, drugs and vaccines. In recent medical literature, only the MMR vaccine (Measles, Mumps and Rubella) was associated with the occurrence of this dise...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20153492
更新日期:2015-05-01 00:00:00
abstract::Christ-Siemens-Touraine syndrome (hypohidrotic ectodermal dysplasia) is a rare syndrome characterized by the triad of absent or reduced sweating, hypotrichosis, and defective dentition. The prominent forehead, saddle nose, thick lower lip and pointy chin produce a distinctive facies. The full syndrome only occurs in m...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962009000200015
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:Intense pulsed light has been used in the treatment of photoaging without a full understanding of its mechanism of action. OBJECTIVE:To study the effect of intense pulsed light on photoaging and on the skin immune response by means of a clinical and histopathological study, evaluating Langerhans cells (CD1)...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962011000600010
更新日期:2011-11-01 00:00:00
abstract::Reticulohistiocytomas represent a group of benign histiocytic dermal proliferations, which occur either sporadically as solitary cutaneous nodules or, when multiple, in association with systemic disease. Due to its nonspecific clinical presentation, reticulohistiocytoma may mimic other benign or malignant skin neoplas...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20187445
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Facial hyperhidrosis is a disease that may lead patients to serious emotional disturbances. Video-assisted thoracic sympathectomy provides excellent resolution of facial hyperhidrosis, but is associated with certain complications. The most frequent and important complication is compensatory hyperhidrosis. Es...
journal_title:Anais brasileiros de dermatologia
pub_type: 临床试验,杂志文章
doi:10.1590/s0365-05962011000300005
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Dermatophytes are filamentous keratinophilic fungi. Trichophyton rubrum is a prevalent infectious agent in tineas and other skin diseases. Drug therapy is considered to be limited in the treatment of such infections, mainly due to low accessibility of the drug to the tissue attacked and development of antifu...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20163643
更新日期:2016-04-01 00:00:00
abstract::Skin infections by Mycobacterium marinum are quite rare in our environment and, therefore, little studied. The majority of the lesions appear three weeks after traumas in aquariums, beaches and fish tanks. Lymph node drainage and systematization of the disease are rare and most lesions disappear in about three years. ...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20153090
更新日期:2015-01-01 00:00:00
abstract::Furuncular myiasis occurs after larvae penetrate on the skin. The disease is characterized by the presence of a nodule with a central hole through which there is serosanguinous exudate drainage. The authors present a case of furuncular myiasis by Dermatobia hominis in which late diagnosis made it necessary to have the...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20142975
更新日期:2014-07-01 00:00:00
abstract::Pigmented Bowen's disease (PBD) is a variant of squamous cell carcinoma in situ and represents less than 2% of cases of Bowen's disease. It is characterized by a sharply demarcated, pigmented plaque with a scaly or crusted surface on intertriginous and genital areas. The authors describe a case of PBD on the penis and...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962012000300023
更新日期:2012-05-01 00:00:00
abstract::There are few populational studies to estimate the dimension of dermatological diseases. We performed a survey with 515 employees from UNESP campus, Botucatu (SP), exploring demographic data, medical appointments and dermatological diagnoses. Additionally, we induced questions about prevalent diseases. Appointments to...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20142875
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Atopic dermatitis is an inflammatory skin disease that can be triggered by many factors. Several reports confirm the role of airborne allergic agents as aggravating or triggering factors. The patch test with airborne allergic agents or the atopy patch test was suggested to evaluate the role of these allergen...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962011000100004
更新日期:2011-01-01 00:00:00
abstract::Gianotti-Crosti syndrome is a rare disease characterized by acral papular eruption with symmetrical distribution. It is a benign and self-limited disease; the symptoms disappear after two to eight weeks, without recurrences or scars. Skin lesions are usually asymptomatic. Prodrome might occur, suggesting upper respira...
journal_title:Anais brasileiros de dermatologia
pub_type:
doi:10.1590/abd1806-4841.20164410
更新日期:2016-09-01 00:00:00
abstract::The number of individuals with tattoos has been increasing worldwide, alongside with reports of complications varying from reactions to the injected pigments to infections caused by agents inoculated in the pigmentation process. The diagnosis of such unwanted events can be obtained through complementary non-invasive m...
journal_title:Anais brasileiros de dermatologia
pub_type:
doi:10.1016/j.abd.2019.02.008
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:In highly endemic countries, transmission and sub-clinical infection of leprosy are likely and the disease manifests itself in individuals without any known close contact with a leprosy patient. Health workers are social contacts belonging to the same network (the Health System) and some of them share the sa...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20132139
更新日期:2013-11-01 00:00:00
abstract::Chronic cutaneous lupus erythematosus in a linear configuration is rare, particularly in children, demonstrating similar incidence in both genders, no photo-sensitivity and lower probability of progression to systemic disease. We describe the case of a 9-year-old girl who presented erythematous papules with central at...
journal_title:Anais brasileiros de dermatologia
pub_type:
doi:10.1590/abd1806-4841.20163800
更新日期:2016-07-01 00:00:00
abstract::Trichilemmoma is a benign neoplasm from the outer sheath of the pilosebaceous follicle. Desmoplastic trichilemmoma, a rare variant, is histologically characterized by a central area of desmoplasia that can clinically mimic an invasive carcinoma, requiring histopathological examination to define the diagnosis. ...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20143095
更新日期:2014-09-01 00:00:00