An overview about oxidation in clinical practice of skin aging.

Abstract:

:Free radicals are unstable chemical species, highly reactive, being formed by cellular entities of different tissues. Increased production of these species without proper effective action of endogenous and exogenous antioxidant systems, generates a condition of oxidative stress, potentially provider of skin disorders that extend from functional impairments (skin cancer, dermatitis, chronic and acute inflammatory processes) even aesthetic character, with the destruction of structural proteins and cellular changes with the appearance of stains, marks and lines of expressions and other signs inherent to the intrinsic and extrinsic skin aging process. The antioxidants are chemical substances commonly used in clinical practice for topical application and may contribute in the fight against the radical species responsible for many skin damage. This paper summarized the main evidence of the benefits brought by the topical application of antioxidants in the skin, considering the amplitude of the indicative performance of antioxidant activity by in vitro and ex-vivo tests as well as in vivo tests. It is recognized that a breadth of product performance tests should be explored to truly identify the effectiveness of antioxidant products for an anti-aging effect.

journal_name

An Bras Dermatol

authors

Silva SAME,Michniak-Kohn B,Leonardi GR

doi

10.1590/abd1806-4841.20175481

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

367-374

issue

3

eissn

0365-0596

issn

1806-4841

pii

S0365-05962017000300367

journal_volume

92

pub_type

杂志文章,评审
  • Pigmented purpura and cutaneous vascular occlusion syndromes.

    abstract::Purpura is defined as a visible hemorrhage in the skin or mucosa, which is not evanescent upon pressure. Proper classification allows a better patient approach due to its multiple diagnoses. Purpuras can be categorized by size, morphology, and other characteristics. The course varies according to the etiology, as do t...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,评审

    doi:10.1590/abd1806-4841.20187459

    authors: Lamadrid-Zertuche AC,Garza-Rodríguez V,Ocampo-Candiani JJ

    更新日期:2018-06-01 00:00:00

  • [Molecular basis of photoaging].

    abstract::As a result of the increase in life expectancy, the study of the organic process of aging has been stimulated. Skin ageing, which reflects the signs of time, is a time-dependent process of progressive deterioration that can be intensified by sun exposure, which is known as photoaging. The damage of radiation on variou...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,评审

    doi:10.1590/s0365-05962009000300008

    authors: Montagner S,Costa A

    更新日期:2009-07-01 00:00:00

  • Wooly hair nevus.

    abstract::Woolly hair nevus is a rare condition characterized by a structural anomaly of the hair, restricted to certain areas of the scalp. The hair becomes coiled and slightly hypopigmented. The term woolly hair refers to changes that affect all the scalp and has a hereditary character. We present a case of woolly hair nevus,...

    journal_title:Anais brasileiros de dermatologia

    pub_type:

    doi:10.1590/abd1806-4841.20175289

    authors: Fernandes KAP,Fernandes KAP,Vargas TJS,Melo DF

    更新日期:2017-01-01 00:00:00

  • Assessment of the quality of life of Egyptian and Tunisian autoimmune bullous diseases' patients using an Arabic version of the autoimmune bullous disease quality of life and the treatment of autoimmune bullous disease quality of life questionnaires.

    abstract:BACKGROUND:The Autoimmune Bullous Disease Quality of Life (ABQOL) and the Treatment of Autoimmune Bullous Disease Quality of Life (TABQOL) questionnaires proved to be reliable tools that measure the disease and treatment burden. OBJECTIVES:We aimed to assess the ABQOL and TABQOL in the Arabic population. METHODS:The ...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20197198

    authors: Saleh MA,Zaraa I,Doss N,Saleh NA,Murrell DF

    更新日期:2019-01-01 00:00:00

  • Oral mucosal diseases in children - casuistics from the Department of Dermatology - University of São Paulo - Brazil.

    abstract::There are no studies about pediatric oral mucosal diseases performed by dermatologists in Brazil. This study presents the casuistics of oral mucosal diseases in children examined at the Oral Diseases Clinic at the Department of Dermatology - University of São Paulo - Brazil. Cases were retrospectively studied from the...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20165424

    authors: Erthal A,Lourenço SV,Nico MM

    更新日期:2016-11-01 00:00:00

  • Pityriasis lichenoides et varioliformis acuta after influenza vaccine.

    abstract::The etiology of pityriasis lichenoides is unknown. One of the accepted theories admits that PL is an inflammatory response to extrinsic antigens such as infectious agents, drugs and vaccines. In recent medical literature, only the MMR vaccine (Measles, Mumps and Rubella) was associated with the occurrence of this dise...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20153492

    authors: Castro BA,Pereira JM,Meyer RL,Trindade FM,Pedrosa MS,Piancastelli AC

    更新日期:2015-05-01 00:00:00

  • Study of 448 cases of melanoma in situ in two hospitals in Rio de Janeiro.

    abstract::The diagnosis of cutaneous melanoma in situ, considered to have excellent prognosis, has been increasingly frequent, with rare isolated reports of cutaneous melanoma in situ presenting recurrence, metastasis, and death. No specific study is found in the literature about these lesions of unexpected behavior. We describ...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,多中心研究

    doi:10.1590/abd1806-4841.20175121

    authors: Pantaleão L,Rochael MC

    更新日期:2017-03-01 00:00:00

  • Case for diagnosis. Suppurative nodule or something deeper?

    abstract::The authors report the case of a 62-year-old man with a history of total left hip arthroplasty nine years previously presenting with a large infiltrated plaque on the posterior area of the left thigh with three months of evolution without systemic symptoms or elevated inflammatory markers. Computed tomography of the l...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20198675

    authors: Gomes NP,Costa-Silva M,Moreira E,Azevedo F

    更新日期:2019-01-01 00:00:00

  • Nuclear morphometry and chromatin textural characteristics of basal cell carcinoma.

    abstract::Histological subtypes of basal cell carcinoma have biological, evolutionary and distinct prognostic behavior. The analysis of characteristics of the nucleus can provide data on their cellular physiology and behavior. The authors of this study evaluated nuclear morphological parameters and textural patterns of chromati...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20154076

    authors: Mendaçolli PJ,Brianezi G,Schmitt JV,Marques ME,Miot HA

    更新日期:2015-11-01 00:00:00

  • Teledermatology protocol for screening of skin cancer.

    abstract:BACKGROUND:Telemedicine refers to the use of technology as improvement of healthcare delivery to places where distance becomes an obstacle. Its use represents a great potential for dermatology, a specialty whose visual analysis phase is essential in diagnosis. OBJECTIVES:To analyze the compatibility index of skin canc...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20153163

    authors: Piccoli MF,Amorim BD,Wagner HM,Nunes DH

    更新日期:2015-03-01 00:00:00

  • Case for diagnosis. Adult-type xanthogranuloma.

    abstract::Male patient, 28 years old, presented with an asymptomatic yellowish erythematous papule on his right thigh. Excisional biopsy was performed for histopathological examination of the lesion. Multinucleated cells (Touton giant cells) were observed. S100 immunohistochemistry was negative for CD1a and positive for CD4 and...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962012000500024

    authors: Sampaio FM,Lourenço FT,Obadia DL,Nascimento LV

    更新日期:2012-09-01 00:00:00

  • Targetoid hemosiderotic hemangioma - Case report.

    abstract::Targetoid Hemosiderotic Hemangioma, also known as Hobnail Hemangioma, is a lesion of vascular origin, probably lymphatic. The most common clinical feature is a solitary violaceous papule surrounded by a pale, thin area and a peripheral ecchymotic ring, simulating a target. Histopathologically, there is a biphasic patt...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20143264

    authors: Kakizaki P,Valente NY,Paiva DL,Dantas FL,Gonçalves SV

    更新日期:2014-11-01 00:00:00

  • Skin barrier in rosacea.

    abstract::Recent studies about the cutaneous barrier demonstrated consistent evidence that the stratum corneum is a metabolically active structure and also has adaptive functions, may play a regulatory role in the inflammatory response with activation of keratinocytes, angiogenesis and fibroplasia, whose intensity depends prima...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,评审

    doi:10.1590/abd1806-4841.20163541

    authors: Addor FA

    更新日期:2016-01-01 00:00:00

  • Ultraviolet radiation protection: current available resources in photoprotection.

    abstract::Ultraviolet radiation can damage the DNA, cause immunosuppression, chemical and histological alterations in the epidermis, early photoaging, cataracts and carcinogenesis, among others. Photoprotection prevents these and other harmful effects of ultraviolet radiation. Sunscreens, protective clothing, proper accessories...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,评审

    doi:10.1590/s0365-05962011000400016

    authors: Balogh TS,Velasco MV,Pedriali CA,Kaneko TM,Baby AR

    更新日期:2011-07-01 00:00:00

  • Pityriasis versicolor circinata: isolation of Malassezia sympodialis - Case report.

    abstract::The authors report a case of pityriasis versicolor circinata whose isolated etiologic agent was Malassezia sympodialis in a 34-year-old woman. The isolation and identification of Malassezia sympodialis were accomplished with modified Dixon's agar, and the molecular method used to confirm the species was polymerase cha...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962010000200015

    authors: Framil VM,Melhem MS,Szeszs MW,Corneta EC,Zaitz C

    更新日期:2010-03-01 00:00:00

  • Do you know this syndrome? Ascher´s syndrome: clinical findings of little known triad.

    abstract::Ascher's syndrome consists of double lip, blepharochalasis and sometimes non-toxic thyroid enlargement. It is a rare, benign, rarely reported, and sometimes misdiagnosed condition that most often affects patients under 20 years old. The etiology remains unknown, although factors such as trauma, hormonal dysfunction an...

    journal_title:Anais brasileiros de dermatologia

    pub_type:

    doi:10.1590/abd1806-4841.20177158

    authors: Donato CMG,Melo DF,Santos JN Netto

    更新日期:2017-09-01 00:00:00

  • Florid cutaneous papillomatosis and acanthosis nigricans maligna revealing gastric adenocarcinoma.

    abstract::This paper reports the case of a 57-year-old, previously healthy male with no systemic symptoms who over a short period of time developed multiple wart-like lesions on his trunk, limbs and face, typical lesions of acanthosis nigricans in the major body folds and tripe palms. Diagnostic tests revealed a metastatic gast...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962011000300025

    authors: Brinca A,Cardoso JC,Brites MM,Tellechea O,Figueiredo A

    更新日期:2011-05-01 00:00:00

  • American cutaneous leishmaniasis: epidemiological profile of patients treated in Londrina from 1998 to 2009.

    abstract:BACKGROUND:American cutaneous leishmaniasis is a dermatozoonosis of compulsory notification with relevant morbidity. The disease is considered endemic in northern Paraná. OBJECTIVES:To evaluate the clinical, laboratory and epidemiological aspects of patients with American cutaneous leishmaniasis treated at Clinics Hos...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20132168

    authors: Pontello Junior R,Gon Ados S,Ogama A

    更新日期:2013-09-01 00:00:00

  • Diffuse plane xanthomatosis associated with monoclonal gammopathy.

    abstract::Diffuse plane normolipemic xanthomatosis (DPNX) is a rare, non-inherited disease that is often associated with systemic diseases, mainly malignant hematological (especially multiple myeloma) or lymph proliferative disorders. The DPNX can precede the appearance of such conditions by several years, so careful follow-up ...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962011000700012

    authors: Rosmaninho A,Fernandes I,Guimas A,Amorim I,Selores M

    更新日期:2011-07-01 00:00:00

  • Primary cutaneous follicle center lymphoma simulating basal-cell carcinoma on the nasal ala.

    abstract::Primary cutaneous B-cell lymphomas (PCBCLs) constitute 25% of all primary cutaneous lymphomas. They present in the skin with no evidence of systemic or extracutaneous disease at the time of diagnosis, after adequate staging. Primary cutaneous B-cell lymphomas differ significantly from their nodal counterparts in relat...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20153768

    authors: Wanczinsnki MI,Pinto CA,Trevisan F,Cunha PR,Grohs LM

    更新日期:2015-05-01 00:00:00

  • Evaluation of cases of pemphigus vulgaris and pemphigus foliaceus from a reference service in Pará state, Brazil.

    abstract:BACKGROUND:Pemphigusis a bullous, rare and chronic autoimmune disease. There are two major forms of pemphigus: vulgaris and foliaceus. Epidemiological data and clinical outcome in patients diagnosed in the Brazilian Amazon states are still rare. OBJECTIVES:To study the occurrence of the disease during the study period...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20142679

    authors: Pires CA,Viana VB,Araújo FC,Müller SF,Oliveira MS,Carneiro FR

    更新日期:2014-07-01 00:00:00

  • Primary systemic amyloidosis associated with multiple myeloma.

    abstract::This case report is about a 48-year-old female patient with systemic amyloidosis and multiple myeloma simultaneously. Amyloid cutaneous infiltrative lesions like papules, nodules, or plaques with a serous-hemorrhagic aspect were found in the eyelids, neck and retroauricular region, among others. She had presented inte...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962012000100015

    authors: Oliveira EV,Pozetti AC,Pozetti EM,Antonio JR,Michalany NS

    更新日期:2012-01-01 00:00:00

  • A rare clinical presentation of Desmoplastic Trichilemmoma mimicking Invasive Carcinoma.

    abstract::Trichilemmoma is a benign neoplasm from the outer sheath of the pilosebaceous follicle. Desmoplastic trichilemmoma, a rare variant, is histologically characterized by a central area of desmoplasia that can clinically mimic an invasive carcinoma, requiring histopathological examination to define the diagnosis. ...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20143095

    authors: Sano DT,Yang JJ,Tebcherani AJ,Bazzo LA

    更新日期:2014-09-01 00:00:00

  • Prevalence of self-medication for skin diseases: a systematic review.

    abstract::Self-medication is the selection and use of drugs without medical prescription, to treat diseases or for symptomatic relief. This article is a systematic review on self-medication in skin diseases. A search was conducted on Virtual Health Library and PubMed databases using predetermined descriptors. Two researchers pe...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,评审

    doi:10.1590/abd1806-4841.20142872

    authors: Corrêa-Fissmer M,Mendonça MG,Martins AH,Galato D

    更新日期:2014-07-01 00:00:00

  • Multisystemic fusariosis with fulminant evolution.

    abstract::This report presents the case of a 13-year-old female patient with history of acute myeloid leukemia, who, after a bone marrow transplant, began to vomit and experienced rapidly progressive deterioration of consciousness, in addition to disseminated erythematous-violaceous macules, and some blisters with hemorrhagic c...

    journal_title:Anais brasileiros de dermatologia

    pub_type:

    doi:10.1016/j.abd.2020.03.007

    authors: Turra N,Acosta A,Incoronato A,Beltramo P

    更新日期:2020-01-01 00:00:00

  • Granuloma faciale: a good therapeutic response with the use of topical tacrolimus.

    abstract::Granuloma faciale is a rare dermatosis of chronic course, benign, usually asymptomatic, first described in 1945 by Wingley. It is characterized by the appearance of well-defined, single or multiple papules, plaques and nodules, predominantly located in sun-exposed areas, especially the face. In this work we report the...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20153339

    authors: Lima RS,Maquiné GÁ,Silva Junior RC,Schettini AP,Santos M

    更新日期:2015-09-01 00:00:00

  • Clinical trial for uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): adverse effects approach.

    abstract:BACKGROUND:The Clinical Trial for Uniform Multidrug Therapy for Leprosy Patients in Brazil (U-MDT/CT-BR), designed to evaluate the effectiveness of a six-months regimen, assessed the adverse effects caused by the drugs. OBJECTIVE:Describe adverse effects due to MDT in U-MDT/CT-BR, comparing the uniform regimen (U-MDT)...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,随机对照试验

    doi:10.1590/abd1806-4841.20186709

    authors: Cruz RCDS,Bührer-Sékula S,Penna GO,Moraes MEA,Gonçalves HS,Stefani MMA,Penna MLF,Pontes MAA,Talhari S

    更新日期:2018-06-01 00:00:00

  • The vegetal biomembrane in the healing of chronic venous ulcers.

    abstract:BACKGROUND:The vegetal biomembrane has been used to treat cutaneous ulcers. OBJECTIVES:To assess the role of the vegetal biomembrane on the chronic venous ulcers treatment compared to treatment with collagenase cream. METHODS:Fourteen patients were selected to be treated with vegetal biomembrane and 7 with Fibrase(®)...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,随机对照试验

    doi:10.1590/s0365-05962012000100005

    authors: Frade MA,Assis RV,Coutinho Netto J,Andrade TA,Foss NT

    更新日期:2012-01-01 00:00:00

  • Syphilis associated with paretic neurosyphilis mimicking Reiter's syndrome in HIV-infected patients.

    abstract::HIV/syphilis co-infection is common because both conditions affect similar risk groups. HIV interferes with the natural history of syphilis, which often has atypical clinical features and nervous system involvement in the early stage of disease. We report the case of an HIV-positive patient with secondary syphilis, sc...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20153625

    authors: Bastos TC,Maia DC,Gomes NM,Menezes CK,Francesconi V,Francesconi F

    更新日期:2015-05-01 00:00:00

  • Periungual basal cell carcinoma.

    abstract::Periungual basal cell carcinoma is rare and needs to be differentiated from other common diseases that affect this region. Several factors are associated with the development of this tumor, and sun damage seems to play an important role in its pathogenesis. Dermoscopy of clinically indolent lesions on the nail unit ca...

    journal_title:Anais brasileiros de dermatologia

    pub_type:

    doi:10.1590/abd1806-4841.20186515

    authors: Tavares LL,Costa JCMD,Delcourt NC,Rodrigues NCDS

    更新日期:2018-01-01 00:00:00