Evaluation of cases of pemphigus vulgaris and pemphigus foliaceus from a reference service in Pará state, Brazil.

Abstract:

BACKGROUND:Pemphigusis a bullous, rare and chronic autoimmune disease. There are two major forms of pemphigus: vulgaris and foliaceus. Epidemiological data and clinical outcome in patients diagnosed in the Brazilian Amazon states are still rare. OBJECTIVES:To study the occurrence of the disease during the study period and analyze the epidemiological profile of patients, the most common subtype of pemphigus, and the clinical evolution of patients. METHODS:Retrospective analysis of medical records of hospitalized patients with pemphigus foliaceus and pemphigus vulgaris in the period from 2003 to 2010 in Dermatology Service of Hospital Fundação Santa Casa de Misericórdia do Pará, Belém, Northern Brazil. RESULTS:We found a total of 20 cases of pemphigus during the study period, 8 of which were of foliaceus pemphigus and 12 of vulgaris pemphigus. Pemphigus foliaceus had the predominance of male patients (75%), showed satisfactory clinical evolution, and was characterized by absence of pediatric cases. Pemphigus vulgaris affected more women (66.7%), showed mean hospital stay of 1 to 3 months (50%), and there were three cases of death (25%). The prescribed immunosuppressive drugs included prednisone with or without combination of azathioprine and/or dapsone. Sepsis was associated with 100% of the deaths. CONCLUSIONS:The occurrence of the disease is rare, there are no familiar/endemic outbreaks in the sample. Evolution is usually favorable, but secondary infection is associated with worse prognosis. The choice of best drugs to treat pemphigus remains controversial.

journal_name

An Bras Dermatol

authors

Pires CA,Viana VB,Araújo FC,Müller SF,Oliveira MS,Carneiro FR

doi

10.1590/abd1806-4841.20142679

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

556-61

issue

4

eissn

0365-0596

issn

1806-4841

pii

S0365-05962014000400556

journal_volume

89

pub_type

杂志文章
  • Treatment of actinic keratoses and cancerization field of the face and scalp with 0.015% ingenol mebutate gel in Brazilian individuals: safety, tolerability and patients' perspectives.

    abstract:BACKGROUND:Actinic keratosis (AK) represents a risk of progression to squamous cell carcinoma. Ingenol mebutate gel is a novel therapeutic option for field-directed treatment. OBJECTIVES:To evaluate the safety, tolerability and patients' perspectives, related to the therapeutic success of managing AKs on the face and ...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20197938

    authors: Gameiro L,Tovo LFR,Sanches Júnior JA,Aprahamian I

    更新日期:2019-07-29 00:00:00

  • Case for diagnosis.

    abstract::A fifty-five year old Caucasian male presented with infiltrated plaques and nodules on the left leg. The lesions had been present for 6 months. He presented associated cardiopathy, nephropathy and endocrinopathy. Histopathological and immunohistochemical examinations confirmed the diagnosis of cutaneous diffuse B cell...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962011000400036

    authors: Salaro CP,Tchernev G

    更新日期:2011-07-01 00:00:00

  • Second-to-fourth digit ratio and seborrheic dermatitis in males: a cross-sectional study.

    abstract:BACKGROUND:Seborrheic dermatitis is a common disease characterized by the erythematous plaques with oily-yellow desquamation. Increased sebaceous gland activity by androgenic hormones has played a role in the etiology of the disease. The second-to-fourth digit (2D:4D) ratio is thought to be a marker of prenatal androge...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20198578

    authors: İslamoğlu ZGK

    更新日期:2019-01-01 00:00:00

  • Proliferating trichilemmal cyst with clinical, radiological, macroscopic, and microscopic correlation.

    abstract::Proliferating trichilemmal cyst is an uncommon neoplasm arising from the follicular isthmus, whose histopathological hallmark is the presence of trichilemmal keratinization. We describe a case of proliferating trichilemmal cyst in a 57-year-old woman with a broad clinical, radiological, macroscopic and microscopic cor...

    journal_title:Anais brasileiros de dermatologia

    pub_type:

    doi:10.1590/abd1806-4841.20198199

    authors: Valerio E,Parro FHS,de Macedo MP,Pinto CAL

    更新日期:2019-01-01 00:00:00

  • Nosological profile of dermatological diseases in primary health care and dermatology secondary care in Florianópolis (2016-2017).

    abstract:BACKGROUND:Dermatology encompasses the management of many disorders of the skin and cutaneous appendages, making the analysis of epidemiological profiles relevant for health planning. OBJECTIVE:The study aims to describe the nosological profile of dermatological diseases in Florianopolis, analyzing the interrelation a...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1016/j.abd.2020.01.004

    authors: Ferreira IG,Godoi DF,Perugini ER

    更新日期:2020-01-01 00:00:00

  • [Molecular basis of photoaging].

    abstract::As a result of the increase in life expectancy, the study of the organic process of aging has been stimulated. Skin ageing, which reflects the signs of time, is a time-dependent process of progressive deterioration that can be intensified by sun exposure, which is known as photoaging. The damage of radiation on variou...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,评审

    doi:10.1590/s0365-05962009000300008

    authors: Montagner S,Costa A

    更新日期:2009-07-01 00:00:00

  • Dermatoscopy: an auxiliary resource for the diagnosis of poroid neoplasms.

    abstract::Poroid neoplasms are benign epithelial proliferations with eccrine sweat gland differentiation. They are a challenging diagnosis because of the clinical heterogeneity, being able to mimic several malignant neoplasms. They are classified into classic poroma, hidroacanthoma simplex, dermal duct tumor and poroid hidraden...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20187570

    authors: Saraiva MIR,Ferreira PS,Avancini J,Valente NYS

    更新日期:2018-01-01 00:00:00

  • [Diffuse plane idiopathic normolipemic xanthoma with hypersplenism].

    abstract::Diffuse plane normolipemic xanthoma is a rare disease, of a group of clinical syndromes called histiocytoses, characterized by the presence of yellowish or yellow-orange plaques, distributed symmetrically on the cutaneous surface and usually accompanied by xanthelasma. It affects mainly adults and it may cause discret...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962010000100010

    authors: Silva DM,Chacha JJ,Wiziack Nde C,Takita LC,Hayashi FK

    更新日期:2010-01-01 00:00:00

  • Assessment of the quality of life of Egyptian and Tunisian autoimmune bullous diseases' patients using an Arabic version of the autoimmune bullous disease quality of life and the treatment of autoimmune bullous disease quality of life questionnaires.

    abstract:BACKGROUND:The Autoimmune Bullous Disease Quality of Life (ABQOL) and the Treatment of Autoimmune Bullous Disease Quality of Life (TABQOL) questionnaires proved to be reliable tools that measure the disease and treatment burden. OBJECTIVES:We aimed to assess the ABQOL and TABQOL in the Arabic population. METHODS:The ...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20197198

    authors: Saleh MA,Zaraa I,Doss N,Saleh NA,Murrell DF

    更新日期:2019-01-01 00:00:00

  • Pityriasis versicolor circinata: isolation of Malassezia sympodialis - Case report.

    abstract::The authors report a case of pityriasis versicolor circinata whose isolated etiologic agent was Malassezia sympodialis in a 34-year-old woman. The isolation and identification of Malassezia sympodialis were accomplished with modified Dixon's agar, and the molecular method used to confirm the species was polymerase cha...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962010000200015

    authors: Framil VM,Melhem MS,Szeszs MW,Corneta EC,Zaitz C

    更新日期:2010-03-01 00:00:00

  • [Incidence of squamous cell carcinoma of the skin in the city of Tubarao (SC)--Brazil in the years 2000, 2003, and 2006].

    abstract:BACKGROUND:A worldwide increasing trend in the incidence of squamous cell carcinoma of the skin has been observed but there are no studies regarding the incidence of this cancer in the Southern region of the State of Santa Catarina. OBJECTIVES:To establish epidemiological data regarding squamous cell carcinoma of the ...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962009000500006

    authors: Nunes DH,Back L,Vieira e Silva R,Medeiros Vde S

    更新日期:2009-09-01 00:00:00

  • Serology with ML Flow test in health professionals from three different states of Brazil.

    abstract:BACKGROUND:In highly endemic countries, transmission and sub-clinical infection of leprosy are likely and the disease manifests itself in individuals without any known close contact with a leprosy patient. Health workers are social contacts belonging to the same network (the Health System) and some of them share the sa...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20132139

    authors: Calado KL,Magnanini MM,Moura RS,Gallo ME,Bührer-Sékula S,Oliveira ML

    更新日期:2013-11-01 00:00:00

  • Ichthyosis associated with widespread tinea corporis: report of three cases.

    abstract::Ichthyoses are a common group of keratinization disorders. A non-inflammatory generalized persistent skin desquamation is observed. It is characterized by increased cell turnover, thickening of the stratum corneum and functional changes of sebaceous and sweat glands. All of these favor fungal proliferation. Dermatophy...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20131854

    authors: Freitas CF,Mulinari-Brenner F,Fontana HR,Gentili AC,Hammerschmidt M

    更新日期:2013-07-01 00:00:00

  • Skin diseases reported by workers from UNESP campus at Rubião Jr, Botucatu-SP (Brazil).

    abstract::There are few populational studies to estimate the dimension of dermatological diseases. We performed a survey with 515 employees from UNESP campus, Botucatu (SP), exploring demographic data, medical appointments and dermatological diagnoses. Additionally, we induced questions about prevalent diseases. Appointments to...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20142875

    authors: Ishiy PS,Silva LR,Penha MÁ,Handel AC,Miot HA

    更新日期:2014-05-01 00:00:00

  • Lymphocytoma cutis on the inguinal region: report of a rare case of benign lymphoproliferative disorder.

    abstract::Lymphocytoma cutis, or benign reactive lymphoid hyperplasia, is an inflammatory skin lesion that mimics clinically and histologically malignant lymphoma. Most cases are idiopathic, but they may also be triggered by multiple factors, such as insect bites, tattoos, injections and herpes zoster. Clinically, the lesions a...

    journal_title:Anais brasileiros de dermatologia

    pub_type:

    doi:10.1590/abd1806-4841.20175555

    authors: Rosa WSC,Girão RJS,Carvalho IMS,Vargas LMML

    更新日期:2017-01-01 00:00:00

  • Efficacy and safety of a single dose pentamidine (7mg/kg) for patients with cutaneous leishmaniasis caused by L. guyanensis: a pilot study.

    abstract:BACKGROUND:There have been few studies on pentamidine in the Americas; and there is no consensus regarding the dose that should be applied. OBJECTIVES:To evaluate the use of pentamidine in a single dose to treat cutaneous leishmaniasis. METHODS:Clinical trial of phase II pilot study with 20 patients. Pentamidine was ...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20153956

    authors: Gadelha EP,Talhari S,Guerra JA,Neves LO,Talhari C,Gontijo B,Silva Junior RM,Talhari AC

    更新日期:2015-11-01 00:00:00

  • Tissue immunostaining for factor XIIIa in dermal dendrocytes of pityriasis alba skin lesions.

    abstract:BACKGROUND:Pityriasis alba affects 1% of the world population and about 9.9% of the children in Brazil. However, its etiology remains uncertain. OBJECTIVE:The objective of the present study was to evaluate the immunoexpression of factor XIIIa in dermal dendrocytes of skin lesions of pityriasis alba. METHOD:Twenty pat...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20142201

    authors: Carneiro FR,Amaral GB,Mendes MD,Quaresma JA

    更新日期:2014-03-01 00:00:00

  • Multisystemic fusariosis with fulminant evolution.

    abstract::This report presents the case of a 13-year-old female patient with history of acute myeloid leukemia, who, after a bone marrow transplant, began to vomit and experienced rapidly progressive deterioration of consciousness, in addition to disseminated erythematous-violaceous macules, and some blisters with hemorrhagic c...

    journal_title:Anais brasileiros de dermatologia

    pub_type:

    doi:10.1016/j.abd.2020.03.007

    authors: Turra N,Acosta A,Incoronato A,Beltramo P

    更新日期:2020-01-01 00:00:00

  • Association between three autoimmune diseases: vitiligo, primary biliary cirrhosis, and Sjögren's syndrome.

    abstract::Although the association of multiple autoimmune diseases has already been widely described, no reports of the association between vitiligo, primary biliary cirrhosis and Sjogren's syndrome were retrieved in the SciELO and PubMed databases. The authors describe the case of a female patient who was diagnosed with primar...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1016/j.abd.2018.07.002

    authors: Abdo-Aguiar LS,Silva de Castro CC

    更新日期:2019-01-01 00:00:00

  • Reactions to the different pigments in tattoos: a report of two cases.

    abstract::Tattoos are defined as the intentional or accidental deposit of pigment into the skin. These pigments have been associated with various dermatoses such as allergic contact dermatitis, lichenoid dermatitis, photoinduced reactions, and granulomatous, sarcoid and pseudolymphomatous reactions. The objective of this report...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962010000500019

    authors: Cruz FA,Lage D,Frigério RM,Zaniboni MC,Arruda LH

    更新日期:2010-09-01 00:00:00

  • Sarcoidosis simulating syringomas.

    abstract::Sarcoidosis is a granulomatous disease of unknown etiology. The skin is commonly affected. Cutaneous manifestations can mimic other diseases and autoimmune disorders. The dermatologist plays a critical role in elucidating the clinical diagnosis and assisting other specialists in the investigation of a systemic disease...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962012000200020

    authors: Rocha DS,Presotto C,Bringel DM,Bomm L,Balassiano E,Alves Mde F

    更新日期:2012-03-01 00:00:00

  • Identification of Leishmania species by high-resolution DNA dissociation in cases of American cutaneous leishmaniasis.

    abstract:BACKGROUND:American cutaneous leishmaniasis is an infectious dermatosis caused by protozoa of the genus Leishmania, which comprises a broad spectrum of clinical manifestations depending on the parasite species involved in the infections and the immunogenetic response of the host. The use of techniques for amplification...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1016/j.abd.2020.02.003

    authors: Veasey JV,Zampieri RA,Lellis RF,Freitas THP,Winter LMF

    更新日期:2020-01-01 00:00:00

  • Dermoscopy of inflammatory breast cancer.

    abstract::Inflammatory breast cancer is an aggressive and infiltrative malignancy that is often misdiagnosed as an infection because of its symptoms and signs of inflammation, delaying proper diagnosis and treatment. We report a case of inflammatory breast cancer showing correlation between dermoscopic and histopathological dia...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20186806

    authors: Vallone MG,González VM,Casas JG,Larralde M

    更新日期:2018-03-01 00:00:00

  • Proliferating trichilemmal cyst with clinical, radiological, macroscopic, and microscopic correlation.

    abstract::Proliferating trichilemmal cyst is an uncommon neoplasm arising from the follicular isthmus, whose histopathological hallmark is the presence of trichilemmal keratinization. We describe a case of proliferating trichilemmal cyst in a 57-year-old woman with a broad clinical, radiological, macroscopic and microscopic cor...

    journal_title:Anais brasileiros de dermatologia

    pub_type:

    doi:10.1590/abd1806-4841.20198199

    authors: Valerio E,Parro FHS,Macedo MP,Pinto CAL

    更新日期:2019-10-17 00:00:00

  • [Sweet's syndrome associated with polycythemia vera].

    abstract::Sweet's syndrome may be associated with hematological malignancies, particularly with acute myelogenous leukemia, but there are few reports of its association with polycythemiavera. We describethe case of a 65-year-old male patient, diagnosed with polycythemiavera, which developedinto paraneoplastic Sweet's syndrome. ...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962009000600014

    authors: Moreira AP,Souza FF,Gaspar NK,Quattrino AL,Vilar EA

    更新日期:2009-11-01 00:00:00

  • Diphencyprone as a therapeutic option in cutaneous metastasis of melanoma. A single-institution experience.

    abstract::Diphencyprone has been reported as a local immunotherapy for cutaneous melanoma metastases. We aim to report cases of melanoma patients treated with diphencyprone in a single Brazilian institution and highlight their outcomes. Since 2012, we have treated 16 melanoma patients with cutaneous metastases with topical diph...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20187162

    authors: Gibbons I,Bertolli E,Lopes Pinto C,Sonagli M,Macedo M,Duprat Neto J

    更新日期:2018-01-01 00:00:00

  • Case for diagnosis: (Ectodermal dysplasia: Christ-Siemens-Touraine syndrome).

    abstract::Christ-Siemens-Touraine syndrome (hypohidrotic ectodermal dysplasia) is a rare syndrome characterized by the triad of absent or reduced sweating, hypotrichosis, and defective dentition. The prominent forehead, saddle nose, thick lower lip and pointy chin produce a distinctive facies. The full syndrome only occurs in m...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962009000200015

    authors: Succi IB,Fontenelle E

    更新日期:2009-03-01 00:00:00

  • Child abuse: skin markers and differential diagnosis.

    abstract::Reports of child abuse have increased significantly. The matter makes most physicians uncomfortable for two reasons: a) Little guidance or no training in recognizing the problem; b - Not understanding its true dimension. The most common form of child violence is physical abuse. The skin is the largest and frequently t...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962011000300015

    authors: Gondim RM,Muñoz DR,Petri V

    更新日期:2011-05-01 00:00:00

  • Case for diagnosis. Solitary violaceous nodule on the toe.

    abstract::Reticulohistiocytomas represent a group of benign histiocytic dermal proliferations, which occur either sporadically as solitary cutaneous nodules or, when multiple, in association with systemic disease. Due to its nonspecific clinical presentation, reticulohistiocytoma may mimic other benign or malignant skin neoplas...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20187445

    authors: Kieselova K,Santiago F,Amado C,Henrique M

    更新日期:2018-01-01 00:00:00

  • Palmar hyperhidrosis: clinical, pathophysiological, diagnostic and therapeutic aspects.

    abstract::Palmar hyperhidrosis affects up to 3% of the population and inflict significant impact on quality of life. It is characterized by chronic excessive sweating, not related to the necessity of heat loss. It evolves from a localized hyperactivity of the sympathetic autonomic system and can be triggered by stressful events...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20165358

    authors: Romero FR,Haddad GR,Miot HA,Cataneo DC

    更新日期:2016-11-01 00:00:00