Prevalence of autoantibodies in a group of hereditary angioedema patients.

Abstract:

:Hereditary Angioedema is a dominantly inherited disease. Routine screening of autoantibodies (AAB) is not recommended for individuals with Hereditary Angioedema; however, prevalence of these antibodies in Hereditary Angioedema patients is not well documented. We aim to determine the prevalence of AAB so that individuals at risk of developing autoimmune diseases can be identified. Fifteen patients with Hereditary Angioedema attended at Clementino Fraga Filho University Hospital accepted to participate in this study. Prevalence of AAB was 40%. Our data indicate high prevalence of AAB in patients with Hereditary Angioedema. Large-scale studies should be considered to determine the significance of these AAB in the follow-up care of patients with Hereditary Angioedema.

journal_name

An Bras Dermatol

authors

Dortas Junior SD,Valle SO,Levy SA,Tortora RP,Abe AT,Pires GV,Papi JA,França AT

doi

10.1590/s0365-05962012000200030

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

332-4

issue

2

eissn

0365-0596

issn

1806-4841

pii

S0365-05962012000200030

journal_volume

87

pub_type

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