Calciphylaxis, a diagnostic and therapeutic challenge: report of a successful case.

Abstract:

:Calciphylaxis, also known as calcific uremic arteriolopathy, is a severe complication often observed in patients with hyperparathyroidism secondary to chronic renal failure, which occurs mainly in women. It is characterized by ischemic tissue loss secondary to progressive vascular compromise. This is a rare and severe condition and its pathogenesis is unclear. The best treatment is prevention, especially in order to maintain adequate levels of calcium and phosphorus. We describe a case of this disease in a patient with hyperparathyroidism secondary to chronic renal failure who underwent medical treatment, surgical debridement and total skin autografts, with resolution of symptoms after 6 months.

journal_name

An Bras Dermatol

authors

Roncada EV,Abreu MA,Pereira MF,Oliveira CC,Nai GA,Soares DF

doi

10.1590/s0365-05962012000500014

subject

Has Abstract

pub_date

2012-09-01 00:00:00

pages

752-5

issue

5

eissn

0365-0596

issn

1806-4841

pii

S0365-05962012000500014

journal_volume

87

pub_type

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