Abstract:
:Potassium iodide, as a saturated solution, is a valuable drug in the dermatologist's therapeutic arsenal and is useful for the treatment of different diseases due to its immunomodulatory features. However, its prescription has become increasingly less frequent in dermatology practice. Little knowledge about its exact mechanism of action, lack of interest from the pharmaceutical industry, the advent of new drugs, and the toxicity caused by the use of high doses of the drug are some possible explanations for that. Consequently, there are few scientific studies on the pharmacological aspects, dosage and efficacy of this drug. Also, there is no conventional standard on how to manipulate and prescribe the saturated solution of potassium iodide, which leads to unawareness of the exact amount of the salt being delivered in grams to patients. Considering that dosage is directly related to toxicity and the immunomodulatory features of this drug, it is essential to define the amount to be prescribed and to reduce it to a minimum effective dose in order to minimize the risks of intolerance and thus improve treatment adherence. This review is relevant due to the fact that the saturated solution of potassium iodide is often the only therapeutic choice available for the treatment of some infectious, inflammatory and immune-mediated dermatoses, no matter whether the reason is specific indication, failure of a previous therapy or cost-effectiveness.
journal_name
An Bras Dermatoljournal_title
Anais brasileiros de dermatologiaauthors
Costa RO,Macedo PM,Carvalhal A,Bernardes-Engemann ARdoi
10.1590/abd1806-4841.20132377subject
Has Abstractpub_date
2013-05-01 00:00:00pages
396-402issue
3eissn
0365-0596issn
1806-4841pii
S0365-05962013000300396journal_volume
88pub_type
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journal_title:Anais brasileiros de dermatologia
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abstract:BACKGROUND:Actinic keratosis (AK) represents a risk of progression to squamous cell carcinoma. Ingenol mebutate gel is a novel therapeutic option for field-directed treatment. OBJECTIVES:To evaluate the safety, tolerability and patients' perspectives, related to the therapeutic success of managing AKs on the face and ...
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journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章,评审
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doi:10.1590/abd1806-4841.20175608
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journal_title:Anais brasileiros de dermatologia
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journal_title:Anais brasileiros de dermatologia
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journal_title:Anais brasileiros de dermatologia
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journal_title:Anais brasileiros de dermatologia
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doi:10.1590/abd1806-4841.20132139
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journal_title:Anais brasileiros de dermatologia
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journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
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journal_title:Anais brasileiros de dermatologia
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doi:10.1590/s0365-05962011000500008
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journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20164891
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journal_title:Anais brasileiros de dermatologia
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journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962012000300003
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journal_title:Anais brasileiros de dermatologia
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journal_title:Anais brasileiros de dermatologia
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journal_title:Anais brasileiros de dermatologia
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journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
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journal_title:Anais brasileiros de dermatologia
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journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962011000200030
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journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20198675
更新日期:2019-01-01 00:00:00
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journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20196864
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abstract:BACKGROUND:Intense pulsed light has been used in the treatment of photoaging without a full understanding of its mechanism of action. OBJECTIVE:To study the effect of intense pulsed light on photoaging and on the skin immune response by means of a clinical and histopathological study, evaluating Langerhans cells (CD1)...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962011000600010
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journal_title:Anais brasileiros de dermatologia
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abstract:BACKGROUND:Atopic dermatitis is an inflammatory skin disease that can be triggered by many factors. Several reports confirm the role of airborne allergic agents as aggravating or triggering factors. The patch test with airborne allergic agents or the atopy patch test was suggested to evaluate the role of these allergen...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962011000100004
更新日期:2011-01-01 00:00:00
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journal_title:Anais brasileiros de dermatologia
pub_type:
doi:10.1016/j.abd.2019.11.016
更新日期:2020-01-01 00:00:00