Neuro-ophthalmology update.

abstract：RATIONALE:Phase I/II studies of autologous hematopoietic stem cell transplantation (HSCT) for multiple sclerosis ( MS) were initiated, based on results of experimental transplantation in animal models of multiple sclerosis and clinical observations in patients treated concomitantly for malignant disease. PATIENTS:Eigh...

journal_title：Journal of neurology

authors： Fassas A,Passweg JR,Anagnostopoulos A,Kazis A,Kozak T,Havrdova E,Carreras E,Graus F,Kashyap A,Openshaw H,Schipperus M,Deconinck E,Mancardi G,Marmont A,Hansz J,Rabusin M,Zuazu Nagore FJ,Besalduch J,Dentamaro T,Fouill

更新日期：2002-08-01 00:00:00

abstract：:Infectious agents have been proposed as potential causes of Alzheimer's disease (AD). Recently, we documented a high prevalence of Helicobacter pylori (Hp) infection in patients with AD. We aim to access the effect of Hp eradication on the AD cognitive (MMSE: Mini Mental State Examination and CAMCOG: Cambridge Cogniti...

journal_title：Journal of neurology

authors： Kountouras J,Boziki M,Gavalas E,Zavos C,Grigoriadis N,Deretzi G,Tzilves D,Katsinelos P,Tsolaki M,Chatzopoulos D,Venizelos I

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Parkinson's disease (PD) is a neurodegenerative disorder characterized by deposition of intraneural inclusion bodies in the brain as well as the enteric nervous system. Emerging concepts regarding the brain-gut axis have been proposed for neurological disorders. Thus, the present study investigat...

journal_title：Journal of neurology

authors： Kim YJ,Lee CM,Kim S,Jang JW,Lee SY,Lee SH

更新日期：2020-02-01 00:00:00

abstract：:Demyelination in multiple sclerosis (MS) may cause damage to the vegetative nervous system. Our objective was to examine cerebral autoregulation assessed via blood pressure and cerebral blood flow velocity fluctuations during head-up tilt table testing. We also investigated the effects of high-dose intravenous cortico...

journal_title：Journal of neurology

authors： Mezei Z,Olah L,Kardos L,Kovacs RK,Csiba L,Csepany T

更新日期：2013-09-01 00:00:00

abstract：:The aim of this study was to analyze the pattern of magnetic resonance diffusion-weighted imaging (DWI) findings in status epilepticus in terms of clinical characteristics. Participants comprised 106 patients with status epilepticus who were admitted to our hospital and underwent DWI. Forty-five patients (42.5 %) show...

journal_title：Journal of neurology

authors： Nakae Y,Kudo Y,Yamamoto R,Dobashi Y,Kawabata Y,Ikeda S,Yokoyama M,Higashiyama Y,Doi H,Johkura K,Tanaka F

更新日期：2016-01-01 00:00:00

abstract：:Neuropsychological deficits and the relationship to brain pathology were examined in 13 primary progressive (PP) and 12 secondary progressive (SP) multiple sclerosis patients with a similar duration of the progressive phase and comparable physical disability. A battery of neuropsychological tests to assess attention, ...

journal_title：Journal of neurology

authors： Foong J,Rozewicz L,Chong WK,Thompson AJ,Miller DH,Ron MA

更新日期：2000-02-01 00:00:00

abstract：:We have investigated how the abnormal head posture and motility in spasmodic torticollis interferes with ecological movements such as combined eye-to-foot whole-body reorientations to visual targets. Eight mildly affected patients and 10 controls voluntarily rotated eyes and body in response to illuminated targets of ...

journal_title：Journal of neurology

authors： Anastasopoulos D,Ziavra N,Pearce R,Bronstein AM

更新日期：2013-08-01 00:00:00

abstract：:Genetic evidence indicates a central role of cerebral accumulation of beta-amyloid (Abeta) in the pathogenesis of Alzheimer's disease (AD). Beside presenilin 1 and 2, three other recently discovered proteins (Aph 1, PEN 2 and nicastrin) are associated with gamma-secretase activity, the enzymatic complex generating Abe...

journal_title：Journal of neurology

authors： Sala Frigerio C,Piscopo P,Calabrese E,Crestini A,Malvezzi Campeggi L,Civita di Fava R,Fogliarino S,Albani D,Marcon G,Cherchi R,Piras R,Forloni G,Confaloni A

更新日期：2005-09-01 00:00:00

abstract：:Cognition and gait appear to be closely related. The chronological interplay between cognitive decline and gait dysfunction is not fully understood. The aim of the present prospective study is investigating whether the dysfunction of specific gait parameters, during specific task and medication conditions, may predict...

journal_title：Journal of neurology

authors： Amboni M,Iuppariello L,Iavarone A,Fasano A,Palladino R,Rucco R,Picillo M,Lista I,Varriale P,Vitale C,Cesarelli M,Sorrentino G,Barone P

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:In December 2019, unexplained cases of pneumonia emerged in Wuhan, China, which were found to be secondary to the novel coronavirus SARS-CoV-2. On March 11, 2020, the WHO declared the Coronavirus Disease 2019 (COVID-2019) outbreak, a pandemic. OBJECTIVE:To clarify the neurological complications of SARS-CoV-...

journal_title：Journal of neurology

authors： Ghannam M,Alshaer Q,Al-Chalabi M,Zakarna L,Robertson J,Manousakis G

更新日期：2020-11-01 00:00:00

abstract：:Cerebral ischemia of 15 min was produced in rats by increasing intracranial pressure above the systolic blood pressure level by infusing artificial cerebrospinal fluid into the cisterna magna. Pulmonary edema was prevented by blocking the vasomotor response with a ganglioplegic agent, and reducing the fluid load by pe...

journal_title：Journal of neurology

authors： Kawakami S,Hossmann KA

更新日期：1977-12-01 00:00:00

abstract：:Prognosis of patients with ischemic stroke requiring mechanical ventilation (MV) has been reported to be poor. However, longterm survival and functional outcome have scarcely been studied and nothing is known about the prevalence of cognitive impairment or depression in survivors and their quality of life (QoL). We id...

journal_title：Journal of neurology

authors： Schielke E,Busch MA,Hildenhagen T,Holtkamp M,Küchler I,Harms L,Masuhr F

更新日期：2005-06-01 00:00:00

abstract：:A clinical and electrophological study was performed on 30 patients with chronic carbon disulphide poisoning. Although the measurements of motor conduction velocity and of terminal latency were within the normal range in the subclinical stage, estimation of nerve excitability threshold showed distal motor hypoexcitabi...

journal_title：Journal of neurology

authors： Vasilescu C,Florescu A

更新日期：1980-01-01 00:00:00

abstract：:The United Nations High Commissioner for Refugees (UNHCR) recognizes 43.7 million forcibly displaced persons and asylum seekers due to conflict and persecution worldwide. Neurological disorders have rarely been described in displaced persons but likely pose a significant burden of disease. We describe the disease spec...

journal_title：Journal of neurology

authors： Mateen FJ,Carone M,Nyce S,Ghosn J,Mutuerandu T,Al-Saedy H,Lowenstein DH,Burnham G

更新日期：2012-04-01 00:00:00

abstract：:Acquired copper deficiency has been recognised as a rare cause of anaemia and neutropenia for over half a century. Copper deficiency myelopathy (CDM) was only described within the last decade, and represents a treatable cause of non-compressive myelopathy which closely mimics subacute combined degeneration due to vita...

journal_title：Journal of neurology

authors： Jaiser SR,Winston GP

更新日期：2010-06-01 00:00:00

abstract：:The occurrence of spontaneous internal carotid or vertebral artery dissection after childbirth remains rare. To our knowledge, seven cases of arterial dissection in the postpartum period have been described in the literature as single case reports. We report four additional cases of internal carotid and vertebral arte...

journal_title：Journal of neurology

authors： Gasecki AP,Kwiecinski H,Lyrer PA,Lynch TG,Baxter T

更新日期：1999-08-01 00:00:00

abstract：:Central nervous system localizations of sarcoidosis may be refractory to conventional treatment such as steroids and immunosuppressive drugs. Infliximab, a TNF-α antagonist chimeric antibody, has been shown to be effective for treatment of these localizations. The aim of this study was to evaluate the efficacy and saf...

journal_title：Journal of neurology

authors： Cohen Aubart F,Bouvry D,Galanaud D,Dehais C,Mathey G,Psimaras D,Haroche J,Pottier C,Hie M,Mathian A,Devilliers H,Nunes H,Valeyre D,Amoura Z

更新日期：2017-05-01 00:00:00

abstract：:Regional cerebral glucose metabolism (rCMRGlc) and dopamine D2 receptor binding were measured in a 31-year-old, severely affected, untreated patient with Wilson's disease of 3 years' duration using positron emission tomography and 18F-deoxyglucose and 18F-methylspiperone ([18F]MSP), respectively. There was a severe re...

journal_title：Journal of neurology

authors： Schlaug G,Hefter H,Nebeling B,Engelbrecht V,Weiss P,Stöcklin G,Seitz RJ

更新日期：1994-10-01 00:00:00

abstract：:Cerebral venous thrombosis (CVT) affects mainly working-aged individuals. Functional recovery after CVT is generally considered good with about 3/4 of patients achieving short-term independence. However, vascular events, long-term functional outcome, and employment after CVT remain poorly investigated. We identified c...

journal_title：Journal of neurology

authors： Hiltunen S,Putaala J,Haapaniemi E,Tatlisumak T

更新日期：2016-03-01 00:00:00

abstract：:To further evaluate (1) transcranial sonography (TCS) for (pre)clinical diagnosis of Parkinson's disease (PD) and (2) to examine asymptomatic carriers of Parkin mutations we investigated substantia nigra (SN) hyperechogenicity in PD patients and unaffected subjects with and without Parkin mutations. The area (aSN) of ...

journal_title：Journal of neurology

authors： Hagenah JM,König IR,Becker B,Hilker R,Kasten M,Hedrich K,Pramstaller PP,Klein C,Seidel G

更新日期：2007-10-01 00:00:00

abstract：:During recent years, evidence has come up that bipedal locomotion is based on a quadrupedal limb coordination. A task-dependent neuronal coupling of upper and lower limbs allows one to involve the arms during gait but to uncouple this connection during voluntarily guided arm/hand movements. Hence, despite the evolutio...

journal_title：Journal of neurology

authors： Dietz V

更新日期：2011-08-01 00:00:00

abstract：:The number of dementia patients requesting euthanasia in the Netherlands has increased over the past five years. The issue is highly controversial. In this contribution we discuss some of the main arguments: the nature of suffering, the voluntariness of the request and the role of the physician. We argue that society ...

journal_title：Journal of neurology

authors： de Beaufort ID,van de Vathorst S

更新日期：2016-07-01 00:00:00

abstract：:Clinical and neuropathological data of a 50-year-old woman with an unusual multisystem degeneration are presented. Clinically the illness was characterized by progressive ataxia with ophthalmoplegia and multiple cranial nerve palsies. Neuropathological investigation showed a severe and selective degeneration of the de...

journal_title：Journal of neurology

authors： Janzer RC,Barontini F

更新日期：1985-01-01 00:00:00

abstract：:Fatigue is a common and frequently disabling symptom of multiple sclerosis (MS). The aim of this study was to develop the Fatigue index Kliniken Schmieder (FKS) for detecting motor fatigue in patients with MS using kinematic gait analysis. The FKS relies on the chaos theoretical term "attractor", which, if unchanged, ...

journal_title：Journal of neurology

authors： Sehle A,Vieten M,Sailer S,Mündermann A,Dettmers C

更新日期：2014-09-01 00:00:00

abstract：:Four cases of mild botulinus type B intoxication are reported with the clinical neurophysiological studies. Electromyographically tetanic stimulation of the N. ulnaris initially led to tetanic potentiation of the muscle action potential. After an interval without any symptoms tetanic reduction became apparent between ...

journal_title：Journal of neurology

authors： Hagenah R,Müller-Jensen A

更新日期：1978-02-14 00:00:00

abstract：OBJECTIVE:To characterize the progression of the cognitive involvement in patients affected by myotonic dystrophy type 1 (DM1) by a longitudinal neuropsychological follow-up study. METHODS:In a previous study we documented an ageing-related decline of frontal and temporal cognitive functions in juvenile/adult forms of...

journal_title：Journal of neurology

authors： Modoni A,Silvestri G,Vita MG,Quaranta D,Tonali PA,Marra C

更新日期：2008-11-01 00:00:00

abstract：:Several studies have reported infection as a possible risk factor for cervical artery dissection (CAD). We retrospectively analyzed several inflammatory parameters of CAD patients with the aim of detecting differences between spontaneous (n = 25) and traumatic (n = 18) CAD. In this case-control study, we observed sign...

journal_title：Journal of neurology

authors： Forster K,Poppert H,Conrad B,Sander D

更新日期：2006-06-01 00:00:00

abstract：:Although most patients with spinal muscular atrophy (SMA) are homozygous for deletion of the SMN1 gene, some patients bear one SMN1 copy with a subtle mutation. Detection of such an intragenic mutation may be helpful not only in confirming diagnosis but also in elucidating functional domains of the SMN protein. In thi...

journal_title：Journal of neurology

authors： Kotani T,Sutomo R,Sasongko TH,Sadewa AH,Gunadi,Minato T,Fujii E,Endo S,Lee MJ,Ayaki H,Harada Y,Matsuo M,Nishio H

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Spontaneous cervical artery dissections (sCAD) are often preceded by infections. However, existing data about inflammatory parameters remained inconsistent. Remarkably, concurrent information about the coagulation system, whose affection seems also reasonable to cause ischaemic events, are still lacking in s...

journal_title：Journal of neurology

authors： Pelz JO,Harms K,Metze M,Michalski D

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Sleep disorders can occur in early Parkinson's disease (PD). However, the relationship between different sleep disturbances and their longitudinal evolution has not been fully explored. OBJECTIVE:To describe the frequency, coexistence, and longitudinal change in excessive daytime sleepiness (EDS), insomnia,...

journal_title：Journal of neurology

authors： Xu Z,Anderson KN,Saffari SE,Lawson RA,Chaudhuri KR,Brooks D,Pavese N

更新日期：2021-01-01 00:00:00