Abstract：
:Four cases of mild botulinus type B intoxication are reported with the clinical neurophysiological studies. Electromyographically tetanic stimulation of the N. ulnaris initially led to tetanic potentiation of the muscle action potential. After an interval without any symptoms tetanic reduction became apparent between the fourth and seventh week of the illness. The electroneurographic finding was normal during the observation period of three months. Infrared reflex pupillographic studies revealed that the cholinergic autonomous synapses were disturbed for a period much longer than the symptoms clinically established. The speed at which the pupillographic findings returned to normal varied considerably according to the patient. Electroencephalographic results indicated generalized groups of slow high amplitude waves in three of the four cases during the period of observation. The pathophysiology of botulinus intoxication is discussed with a consideration of the literature and the results of this study.
journal_name
J Neuroljournal_title
Journal of neurologyauthors
Hagenah R,Müller-Jensen Adoi
10.1007/BF00312957subject
Has Abstractpub_date
1978-02-14 00:00:00pages
159-71issue
3eissn
0340-5354issn
1432-1459journal_volume
217pub_type
杂志文章abstract：:The problem of consciousness is discussed briefly, including the contrary views of consciousness as a transcendental phenomenon and as an animistic fiction. Measurement of consciousness is possible only indirectly by means of quantitative assessment of accompanying behavioral deficits. Knowledge of the structural basi...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00313364
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journal_title：Journal of neurology
pub_type： 杂志文章,多中心研究
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abstract：:Genetic evidence indicates a central role of cerebral accumulation of beta-amyloid (Abeta) in the pathogenesis of Alzheimer's disease (AD). Beside presenilin 1 and 2, three other recently discovered proteins (Aph 1, PEN 2 and nicastrin) are associated with gamma-secretase activity, the enzymatic complex generating Abe...
journal_title：Journal of neurology
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doi：10.1007/s00415-005-0799-7
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doi：10.1007/BF00858729
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pub_type： 杂志文章,评审
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pub_type： 杂志文章
doi：10.1007/s00415-020-09881-6
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-015-7996-9
更新日期：2016-03-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-002-0905-z
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00313342
更新日期：1980-01-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章
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更新日期：2001-01-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-018-9075-5
更新日期：2018-12-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00313391
更新日期：1982-01-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s00415-020-09953-7
更新日期：2020-10-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章,评审
doi：10.1007/pl00022914
更新日期：2000-04-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章,评审
doi：10.1007/s00415-003-1103-1
更新日期：2003-02-01 00:00:00
abstract：:In 12 ambulant patients with a clinical diagnosis of probable Alzheimer's disease, a 12-week, double-blind, placebo-controlled study with 100 mg/day tetrahydroaminoacridine (THA) and 10 g/day lecithin is reported. The aim of the study was to find whether treatment would result in an improvement of cognition, of functi...
journal_title：Journal of neurology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF00319708
更新日期：1991-02-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Parkinson's disease (PD) reduces independence and quality of life through deterioration of upper limb motor function. Transcranial direct current stimulation (tDCS) may offer an alternative, adjunctive therapy for PD. However, the efficacy of tDCS for upper limb motor rehabilitation in PD is unkn...
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pub_type： 杂志文章,评审
doi：10.1007/s00415-019-09385-y
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journal_title：Journal of neurology
pub_type： 杂志文章,评审
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00869769
更新日期：1993-12-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章
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更新日期：2017-10-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-005-0907-8
更新日期：2005-12-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00919594
更新日期：1995-03-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00314221
更新日期：1989-01-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s00415-009-5401-2
更新日期：2010-05-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章,评审
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journal_title：Journal of neurology
pub_type： 杂志文章,评审
doi：10.1007/s00415-002-1307-y
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-016-8095-2
更新日期：2016-07-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章,评审
doi：10.1007/BF00819560
更新日期：1992-01-01 00:00:00
