Relationship between cortex and pulvinar abnormalities on diffusion-weighted imaging in status epilepticus.


:The aim of this study was to analyze the pattern of magnetic resonance diffusion-weighted imaging (DWI) findings in status epilepticus in terms of clinical characteristics. Participants comprised 106 patients with status epilepticus who were admitted to our hospital and underwent DWI. Forty-five patients (42.5 %) showed abnormal findings on DWI and were divided into two groups, comprising 26 patients (24.5 %) with cortex lesions alone and 19 patients (17.9 %) with cortex and pulvinar lesions in the same hemisphere. A long duration of status epilepticus (>120 min) tended to be more prevalent among patients with cortex and pulvinar lesions (57.9 %) than among patients with cortex lesions alone (30.8 %) by univariate and multivariate analyses. Todd's palsy tended to be more frequent in patients with abnormalities on DWI (24/45, 53.3 %) than in patients with normal DWI (21/61, 34.4 %). Six of the 26 patients with cortex lesions alone (23.1 %) had taken anti-epileptic drugs before the attack compared to none of the 19 patients with both cortex and pulvinar lesions. The trend toward a longer duration of status epilepticus in patients with both cortex and pulvinar lesions favors a spreading pattern of seizure discharge from cortex to pulvinar via cortico-pulvinar pathways, and anti-epileptic drugs might, to some extent, prevent spreading of seizure discharge from cortex to pulvinar. In addition, existence of high-intensity areas on DWI at the onset of epilepsy may be a predictive factor for the occurrence of Todd's palsy.


J Neurol


Journal of neurology


Nakae Y,Kudo Y,Yamamoto R,Dobashi Y,Kawabata Y,Ikeda S,Yokoyama M,Higashiyama Y,Doi H,Johkura K,Tanaka F




Has Abstract


2016-01-01 00:00:00














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    authors: Wieske L,Wijers D,Richard E,Vergouwen MD,Stam J

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    pub_type: 杂志文章


    authors: Fawcett K,Mehrabian M,Liu YT,Hamed S,Elahi E,Revesz T,Koutsis G,Herscheson J,Schottlaender L,Wardle M,Morrison PJ,Morris HR,Giunti P,Wood N,Houlden H

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    journal_title:Journal of neurology

    pub_type: 临床试验,杂志文章


    authors: Wildemann B,Jansen O,Haas J,Vogt-Schaden ME,Storch-Hagenlocher B

    更新日期:2001-02-01 00:00:00

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    authors: Grothe M,Lotze M,Langner S,Dressel A

    更新日期:2016-06-01 00:00:00

  • Classic ataxia-telangiectasia: the phenotype of long-term survivors.

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    journal_title:Journal of neurology

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    abstract::Three cases of Fahr's syndrome are described. All patients had disturbances of calcium metabolism and had had a meningoencephalitis in childhood. It is suggested that gliovascular changes, induced by cerebral inflammation, can later facilitate the occurrence of calcification of the striopallidodentate system when abno...

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    authors: Morgante L,Vita G,Meduri M,Di Rosa AE,Galatioto S,Coraci MA,Di Perri R

    更新日期:1986-02-01 00:00:00

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    journal_title:Journal of neurology

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    authors: Passier PE,Post MW,van Zandvoort MJ,Rinkel GJ,Lindeman E,Visser-Meily JM

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    authors: Deschauer M,Gaul C,Behrmann C,Prokisch H,Zierz S,Haack TB

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  • Combining short interval MRI in Alzheimer's disease: Implications for therapeutic trials.

    abstract::Cerebral atrophy calculated from serial MRI is a marker of Alzheimer's disease (AD) progression, and a potential outcome measure for therapeutic trials. Reducing within-subject variability in cerebral atrophy rates by acquiring more than two serial scans could allow for shorter clinical trials requiring smaller patien...

    journal_title:Journal of neurology

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    authors: Schott JM,Frost C,Whitwell JL,Macmanus DG,Boyes RG,Rossor MN,Fox NC

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    journal_title:Journal of neurology

    pub_type: 杂志文章


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    authors: Airla N,Luomala M,Elovaara I,Kettunen E,Knuutila S,Lehtimäki T

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    pub_type: 杂志文章


    authors: Sarasso E,Agosta F,Piramide N,Bianchi F,Butera C,Gatti R,Amadio S,Del Carro U,Filippi M

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    journal_title:Journal of neurology

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    journal_title:Journal of neurology

    pub_type: 杂志文章


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    更新日期:1994-02-01 00:00:00

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    pub_type: 杂志文章


    authors: Sakakibara R,Yamamoto T,Uchiyama T,Liu Z,Ito T,Yamazaki M,Awa Y,Yamanishi T,Hattori T

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    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Renard D,Nerrant E,Lechiche C

    更新日期:2015-09-01 00:00:00

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    pub_type: 杂志文章


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    pub_type: 杂志文章


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    更新日期:2006-08-01 00:00:00

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    pub_type: 杂志文章


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    更新日期:2021-01-01 00:00:00

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    journal_title:Journal of neurology

    pub_type: 杂志文章


    authors: Sjaastad O,Sjaastad OV

    更新日期:1977-09-12 00:00:00