Are energy and energy-providing nutrients related to exocrine carcinoma of the pancreas?

abstract：:Neuron-specific src mRNA, which is expressed in human brain tissue by alternative splicing, is associated with neural differentiation. Neuronal c-srcNI expression may be associated with the ability of neuroblastomas to mature; furthermore, c-srcN2 mRNA is induced in chemically differentiated neuroblastoma cells in vit...

journal_title：International journal of cancer

authors： Matsunaga T,Shirasawa H,Tanabe M,Ohnuma N,Kawamura K,Etoh T,Takahashi H,Simizu B

更新日期：1994-09-15 00:00:00

abstract：:Previous studies have been inconsistent with respect to the reported associations between phospho-Akt (p-Akt) overexpression and lung cancer prognosis. In this study, we conducted a systematic review and meta-analysis to assess the prognostic value of p-Akt in patients with non-small cell lung carcinoma (NSCLC). Relev...

journal_title：International journal of cancer

authors： Yang Y,Luo J,Zhai X,Fu Z,Tang Z,Liu L,Chen M,Zhu Y

更新日期：2014-09-15 00:00:00

abstract：:Although aneuploidy is commonly observed in human cancers, the molecular mechanism underlying aneuploidization remains unclear. We used multiploid cancer model that had diploid and aneuploid cancer cells within the same cancerous tissue and attempted to detect specific epigenetic alterations associated with tumor cell...

journal_title：International journal of cancer

authors： Habano W,Sugai T,Jiao YF,Nakamura S

更新日期：2007-10-01 00:00:00

abstract：:Residential proximity to electrical power lines of different voltage in relation to childhood leukemia was investigated through a case-control study undertaken in Greece during 1993-1994. The study comprised 117 incident cases of childhood leukemia and 202 age-, gender- and place-of-residence-matched controls. Four me...

journal_title：International journal of cancer

authors： Petridou E,Trichopoulos D,Kravaritis A,Pourtsidis A,Dessypris N,Skalkidis Y,Kogevinas M,Kalmanti M,Koliouskas D,Kosmidis H,Panagiotou JP,Piperopoulou F,Tzortzatou F,Kalapothaki V

更新日期：1997-11-04 00:00:00

abstract：:Transforming growth factor-beta (TGF-beta1) is a potent negative regulator of cell growth that transduces signals through interactions with type I and II receptors. Abnormal expression and mutational alterations of these receptors have been observed in several human malignancies. In this study, we investigated the exp...

journal_title：International journal of cancer

authors： Guo Y,Jacobs SC,Kyprianou N

更新日期：1997-05-16 00:00:00

abstract：:Murine SCC-VII squamous carcinoma cells have the capacity to penetrate reconstituted basement membranes (Matrigel) in vitro. The invasion of Matrigel layers by SCC-VII cells was significantly reduced by E-64, a specific inhibitor of lysosomal cysteine proteinases. The cathepsin-B-selective E-64 derivative, CA-074, inh...

journal_title：International journal of cancer

authors： Coulibaly S,Schwihla H,Abrahamson M,Albini A,Cerni C,Clark JL,Ng KM,Katunuma N,Schlappack O,Glössl J,Mach L

更新日期：1999-11-12 00:00:00

abstract：:Heat shock protein (HSP) gp96/grp94 contains a signal peptide at the amino terminus and a -KDEL sequence at the carboxy terminus and is a major component of the lumen of the mammalian endoplasmic reticulum (ER). We show, by a number of immunolocalization methods using light and electron microscopy, that a significant ...

journal_title：International journal of cancer

authors： Altmeyer A,Maki RG,Feldweg AM,Heike M,Protopopov VP,Masur SK,Srivastava PK

更新日期：1996-08-22 00:00:00

abstract：:Our aim was to evaluate whether serum concentrations of squamous cell carcinoma antigen (SCC-Ag) are an independent prognostic factor in patients with vulvar cancer. We measured SCC-Ag in pretreatment serum samples of 55 patients with squamous cell vulvar cancer, 30 patients with vulvar intraepithelial neoplasia (VIN)...

journal_title：International journal of cancer

authors： Hefler L,Obermair A,Tempfer C,van Houte M,Maenner G,Reinthaller A,Leodolter S,Kainz C

更新日期：1999-06-21 00:00:00

abstract：:Novel classes of drug that interfere with the signalling of the small G-protein Ras, the so-called Ras antagonists, are showing much promise as novel anti-cancer agents. In this study, we demonstrate that the novel Ras antagonist farnesylthiosalicylic acid (FTS) inhibits the growth of Colo 853 melanoma cells through a...

journal_title：International journal of cancer

authors： Smalley KS,Eisen TG

更新日期：2002-04-01 00:00:00

abstract：:No animal model exists for the in vivo growth of Hodgkin's-lymphoma-derived cells. Neither unmanipulated Hodgkin's-disease(HD)-derived cell lines nor primary biopsy tissue could be grown in nude mice. Since the severe combined immunodeficient (SCID) mouse has been reported to be a better recipient for transplanted hum...

journal_title：International journal of cancer

authors： von Kalle C,Wolf J,Becker A,Sckaer A,Munck M,Engert A,Kapp U,Fonatsch C,Komitowski D,Feaux de Lacroix W

更新日期：1992-12-02 00:00:00

abstract：:Tumors can induce the generation and accumulation of immunosuppressive cells such as myeloid-derived suppressor cells (MDSCs) in a tumor microenvironment, contributing to tumor escape from immunological attack. Although dendritic cell-based cancer vaccines can initiate antitumor immune responses, tumor-educated dendri...

journal_title：International journal of cancer

authors： Ning Y,Xu D,Zhang X,Bai Y,Ding J,Feng T,Wang S,Xu N,Qian K,Wang Y,Qi C

更新日期：2016-06-01 00:00:00

abstract：:The association between the consumption of preserved foods in infancy, childhood and adulthood and the risk of nasopharyngeal carcinoma was investigated in a case-control study among Singapore Chinese: 200 cases (73% male) were compared with 406 hospital controls (71% male). Significantly increased risks were observed...

journal_title：International journal of cancer

authors： Lee HP,Gourley L,Duffy SW,Esteve J,Lee J,Day NE

更新日期：1994-12-01 00:00:00

abstract：:In mammals, transforming growth factor-beta (TGF-beta) is found in 3 highly homologous isoforms that exert their effects via heteromeric complexes of type-I and type-II receptors (TbetaR-I and TbetaR-II). TGF-beta regulates the growth and metabolism of various cell types, including keratinocytes. We have investigated ...

journal_title：International journal of cancer

authors： Furue M,Kato M,Nakamura K,Nashiro K,Kikuchi K,Okochi H,Miyazono K,Tamaki K

更新日期：1997-05-16 00:00:00

abstract：:Cytotoxic antibodies against glioblastoma-associated antigen(s) have been sought for in glioma patient sera. Complement-dependent cytotoxicity (CDC) I and antibody-dependent cell-mediated cytotoxicity (ADCC) assays were used to test sera from 80 patients using 51 Cr labelled target cells derived from eight different g...

journal_title：International journal of cancer

authors： Martin-Achard A,Diserens AC,de Tribolet N,Carrel S

更新日期：1980-02-15 00:00:00

abstract：:The clonotypic T-cell receptor (TCR) is a potential target antigen for specific immunotherapy of cutaneous T-cell lymphoma (CTCL). We identified T-cell epitopes from the rearranged TCR beta chain of the malignant T-cell population by the "reverse immunology" approach. Peptide-specific T-cell lines were generated again...

journal_title：International journal of cancer

authors： Zeng J,Müller-Berghaus J,Nguyen XD,Klüter H,Schönhaber H,Song M,Schwinn N,Schadendorf D,Goerdt S,Eichmüller S,Dippel E

更新日期：2006-11-15 00:00:00

abstract：:The involvement of 12-lipoxygenase (12-LOX) expression and function in tumor metastasis has been demonstrated in several murine tumor cell lines. In addition, 12-LOX expression was detected in human prostatic tumors and correlated to the clinical stage of disease. Here we provide data that human prostate cancer cell l...

journal_title：International journal of cancer

authors： Timár J,Rásó E,Döme B,Li L,Grignon D,Nie D,Honn KV,Hagmann W

更新日期：2000-07-01 00:00:00

abstract：:To assess the effect of different hospital types or surgical volume on the survival of ovarian cancer patients, a nationwide and population-based analysis was carried out in Finland. The study included all 3,851 ovarian cancer patients operated from 1983-94. The patients were classified according to the hospital of th...

journal_title：International journal of cancer

authors： Kumpulainen S,Grénman S,Kyyrönen P,Pukkala E,Sankila R

更新日期：2002-12-10 00:00:00

abstract：:Several lines of evidence suggest that long-term treatment with non-steroidal anti-inflammatory drugs may reduce the risk of colon cancer and the size and number of colonic polyps in patients with familial adenomatous polyposis. Aspirin has also been shown to inhibit cell proliferation in human tumor cell lines and to...

journal_title：International journal of cancer

authors： Ricchi P,Pignata S,Di Popolo A,Memoli A,Apicella A,Zarrilli R,Acquaviva AM

更新日期：1997-12-10 00:00:00

abstract：:A mammographic breast cancer screening programme has been ongoing in the Florence District (Italy) since 1970 and a favourable impact of screening on breast cancer mortality of women aged 50-70 has been shown by means of a case-control study. Two hundred and eleven screen- and 116 interval-detected cancers in the peri...

journal_title：International journal of cancer

authors： Paci E,Ciatto S,Buiatti E,Cecchini S,Palli D,Rosselli del Turco M

更新日期：1990-08-15 00:00:00

abstract：:In the present study we examined the expression of concanavalin-A(Con-A)-like molecules on natural-killer (NK)-sensitive target cells and investigated their possible role in the human NK-cell phenomenon. The incubation of either peripheral-blood lymphocytes (PBL) or large granular lymphocytes (LGL) with swainsonine (S...

journal_title：International journal of cancer

authors： Yagita M,Noda I,Maehara M,Fujieda S,Inoue Y,Hoshino T,Saksela E

更新日期：1992-10-21 00:00:00

abstract：:Inbred rats were hyper-immunised against a syngeneic transplanted mammary carcinoma, Sp4, which originally arose spontaneously in a breeding female. Spleen cells from Sp4-immune rats were fused with P3-NSI-Ag4 mouse myeloma cells, and supernatants from the hybrid progeny were screened for antibody reacting with Sp4 ce...

journal_title：International journal of cancer

authors： Gunn B,Embleton MJ,Middle JG,Baldwin RW

更新日期：1980-09-15 00:00:00

abstract：:Cancer-germline genes (CGGs) code for immunogenic antigens that are present on various human tumors but not on normal tissues. The importance of CGGs in cancer immunotherapy has led to detailed studies of their expression in a range of human tumors. We measured the levels of expression of 12 CGGs in various pediatric ...

journal_title：International journal of cancer

authors： Jacobs JF,Brasseur F,Hulsbergen-van de Kaa CA,van de Rakt MW,Figdor CG,Adema GJ,Hoogerbrugge PM,Coulie PG,de Vries IJ

更新日期：2007-01-01 00:00:00

abstract：:Specific estrogen, progesterone and androgen receptors were determined in 19 well-characterized squamous-cell carcinoma (SCC) cell lines. Ten of the lines were derived from patients with SCC of the larynx and nine were from patients with SCC originating in other areas of the head and neck. Estrogen receptors (ER) were...

journal_title：International journal of cancer

authors： Virolainen E,Vanharanta R,Carey TE

更新日期：1984-01-15 00:00:00

abstract：:Experimental and epidemiological data support a role for sex steroid hormones in the pathogenesis of endometrial cancer. The associations of pre-diagnostic blood concentrations of estradiol, estrone, testosterone, androstenedione, DHEAS and SHBG with endometrial cancer risk were investigated. A case-control study was ...

journal_title：International journal of cancer

authors： Lukanova A,Lundin E,Micheli A,Arslan A,Ferrari P,Rinaldi S,Krogh V,Lenner P,Shore RE,Biessy C,Muti P,Riboli E,Koenig KL,Levitz M,Stattin P,Berrino F,Hallmans G,Kaaks R,Toniolo P,Zeleniuch-Jacquotte A

更新日期：2004-01-20 00:00:00

abstract：:In order to analyze the mutational events and to understand the biological significance of the p53 gene in chemical carcinogenesis, we applied a new yeast-based p53 functional assay to ovarian tumors induced by 7, 12-dimethylbenz[a]anthracene (DMBA), as well as to transitional cell carcinomas of the urinary bladder in...

journal_title：International journal of cancer

authors： Yamamoto K,Nakata D,Tada M,Tonoki H,Nishida T,Hirai A,Ba Y,Aoyama T,Hamada J,Furuuchi K,Harada H,Hirai K,Shibahara N,Katsuoka Y,Moriuchi T

更新日期：1999-11-26 00:00:00

abstract：:An investigation was carried out to establish whether the reduction in catalase, glutathione peroxidase and superoxide dismutase activity, normally observed in liver tumours, is an early event and therefore of pathogenetic importance, or whether it is a late occurrence. Experiments performed on dimethylnitrosamine-tre...

journal_title：International journal of cancer

authors： Liotti FS,Menghini AR,Guerrieri P,Mariucci G,Locci P,Bruschelli G

更新日期：1988-11-15 00:00:00

abstract：:In EBV-immortalized lymphoblastoid cell lines (LCLs) a small number of "latent" proteins are expressed. These are the EBV nuclear antigens, EBNAs 1-6, and a latent membrane protein, LMP. We have investigated the expression of these proteins in a variety of EBV-associated tumours and cell lines. Whereas transplant and ...

journal_title：International journal of cancer

authors： Allday MJ,Kundu D,Finerty S,Griffin BE

更新日期：1990-06-15 00:00:00

abstract：:Clinical trials utilizing strategies to manipulate tumor oxygenation, blood flow and angiogenesis are under way, although limited quantitative information exists regarding basic tumor pathophysiology. The current study utilized murine KHT fibrosarcomas, spontaneous mammary carcinomas and first-generation spontaneous t...

journal_title：International journal of cancer

authors： Fenton BM,Lord EM,Paoni SF

更新日期：2001-09-01 00:00:00

abstract：:Monoclonal antibody 38.13 was raised against the Burkitt lymphoma cell line Daudi and has been previously shown to recognize a globotriaosylceramide (Pk) determinant expressed selectively on Burkitt and a few other B-cell lymphomas. We report here that 38.13 binds to a subset of normal B lymphocytes in germinal centre...

journal_title：International journal of cancer

authors： Murray LJ,Habeshaw JA,Wiels J,Greaves MF

更新日期：1985-11-15 00:00:00

abstract：:Expression of the macrophage antigen CD163 in breast cancer cells is recently shown to be related to early distant recurrence and shortened survival. In this study, 163 patients with rectal cancer, included in the Swedish rectal cancer trial and followed up for a median of 71 months, were examined for the expression o...

journal_title：International journal of cancer

authors： Shabo I,Olsson H,Sun XF,Svanvik J

更新日期：2009-10-15 00:00:00