1H magnetic resonance spectroscopy in multiple sclerosis and related disorders.

Abstract:

:Proton magnetic resonance spectroscopy ((1)H-MRS) is an unconventional technique that allows noninvasive characterization of metabolic abnormalities in the central nervous system. (1)H-MRS provides important insights into the chemical-pathologic changes that occur in patients with multiple sclerosis (MS). In this review article we present the main brain and spinal cord (1)H-MRS features in MS, their diagnostic value in differentiating pseudotumoral demyelinating lesions from primary brain tumors, and their relationship with clinical variables. Last, some data related to the use of (1)H-MRS in therapeutic trials is presented.

journal_name

Neuroimaging Clin N Am

authors

Rovira A,Alonso J

doi

10.1016/j.nic.2013.03.005

subject

Has Abstract

pub_date

2013-08-01 00:00:00

pages

459-74

issue

3

eissn

1052-5149

issn

1557-9867

pii

S1052-5149(13)00019-1

journal_volume

23

pub_type

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