Abstract:
:Proton magnetic resonance spectroscopy ((1)H-MRS) is an unconventional technique that allows noninvasive characterization of metabolic abnormalities in the central nervous system. (1)H-MRS provides important insights into the chemical-pathologic changes that occur in patients with multiple sclerosis (MS). In this review article we present the main brain and spinal cord (1)H-MRS features in MS, their diagnostic value in differentiating pseudotumoral demyelinating lesions from primary brain tumors, and their relationship with clinical variables. Last, some data related to the use of (1)H-MRS in therapeutic trials is presented.
journal_name
Neuroimaging Clin N Amjournal_title
Neuroimaging clinics of North Americaauthors
Rovira A,Alonso Jdoi
10.1016/j.nic.2013.03.005subject
Has Abstractpub_date
2013-08-01 00:00:00pages
459-74issue
3eissn
1052-5149issn
1557-9867pii
S1052-5149(13)00019-1journal_volume
23pub_type
杂志文章,评审abstract::Spinal vascular malformations (AVMs) are rare but important causes of treatable myelopathies. Recent advances in the interventional neuroradiology and neurosurgical techniques have improved the delineation and classification of these heterogeneous lesions. Because MR imaging usually is the first screening test for pat...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:2001-02-01 00:00:00
abstract::Fungal sinusitis is characterized into invasive and noninvasive forms. The invasive variety is further classified into acute, chronic and granulomatous forms; and the noninvasive variety into fungus ball and allergic fungal sinusitis. Each of these different forms has a unique radiologic appearance. The clinicopatholo...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2015.07.004
更新日期:2015-11-01 00:00:00
abstract::Imaging of the postoperative spine is common, although it remains a difficult task for radiologists. This article presents an overview of common surgical approaches and spinal hardware, and specific complications that may be associated with each procedure. In addition, expected postoperative changes and complications ...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2014.01.002
更新日期:2014-05-01 00:00:00
abstract::High resolution computed tomography has proved to be invaluable in the evaluation of the temporal bone, and demonstrates its bony anatomy in exquisite detail. Furthermore, the role of magnetic resonance imaging, especially with improving high resolution techniques, has continued to expand in the past decade. A thoroug...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1998-02-01 00:00:00
abstract::There are increasing applications and use of spectral computed tomography or dual-energy computed tomography (DECT) in neuroradiology and head and neck imaging in routine clinical practice. Part 1 of this 2-part review covered fundamental physical principles underlying DECT scanning and the different approaches for sc...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2017.03.003
更新日期:2017-08-01 00:00:00
abstract::Computed tomography is often the first-line diagnostic imaging modality in the evaluation of patients with neurologic emergencies. A patient-centered approach to radiation dose management in emergent neuroimaging thus revolves around the appropriate use of computed tomography, including clinical decision support for o...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2018.03.010
更新日期:2018-08-01 00:00:00
abstract::This article focuses on the indications for anterior cervical surgery, relevant surgical anatomy, a brief description of the technique of anterior surgery followed by a discussion of results and complications. It is hoped that the reader will achieve a better understanding for the clinical syndrome of cervical disc de...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1995-08-01 00:00:00
abstract::In addition to basic image-guided injections, there are many advanced procedures to address the challenges of spine pain. Patients with debilitating symptoms are offered relief, a shorter recovery period, and fewer potential complications. Pain arises from numerous sites along the spine, presenting as spine pain or ra...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2019.07.005
更新日期:2019-11-01 00:00:00
abstract::This article reviews the current status and trends in the treatment of primary gliomas, focusing predominantly on glioblastoma. It also discusses the current standard of care and new targeted agents currently under investigation. Furthermore, the concepts of pseudoprogression and pseudoresponse are introduced, which a...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2009.08.015
更新日期:2009-11-01 00:00:00
abstract::Functional MR imaging (fMRI) is being used increasingly to explore the human central auditory system. The considerable background noise produced by echo-planar imaging (EPI) and other fMRI sequences, however, interferes in an unpredictable way with the experimental stimuli. Several approaches exist to overcome this pr...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:2001-05-01 00:00:00
abstract::Approximately 30,000 spinal injuries occur in the United States every year. Injuries to the spine and its contents affect predominately young, healthy individuals and are a major cause of disability, with significant socioeconomic consequences. The main cause for spinal injuries is blunt trauma, most commonly caused b...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2006.11.006
更新日期:2007-02-01 00:00:00
abstract::One of the major pitfalls faced by physicians is a basic lack of understanding of the legal aspects of medical malpractice. It is the authors' hope that the brief review of the history of malpractice law provided here affords the radiologist insights that could prove helpful in understanding how one must conduct onese...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2012.05.012
更新日期:2012-08-01 00:00:00
abstract::The neuroimaging of hydrocephalus from the perspective of the pediatric neurosurgeon is discussed. Processes with new developments in therapy and imaging are described, including congenital causes of hydrocephalus, unilateral hydrocephalus, trapped fourth ventricle, and benign external hydrocephalus. ...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1999-02-01 00:00:00
abstract::Neuroimaging is a potentially valuable tool to link individual differences in the human genome to structure and functional variations, narrowing the gaps in the casual chain from a given genetic variation to a brain disorder. Because genes are not usually expressed at the level of mental behavior, but are mediated by ...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2014.09.005
更新日期:2015-02-01 00:00:00
abstract::This article presents the advantages and challenges of MR angiography of the intracranial and extracranial cerebral vasculature at 3.0 T with comparative assessment to 1.5 T approaches. The physical basis for the superiority of 3.0 T MR angiography is discussed in the context of evolving technological capabilities aff...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2006.03.002
更新日期:2006-05-01 00:00:00
abstract::Arterial supply of hippocampal formation in humans has been studied by many investigators in the past. More recently, investigation of correlation of complex partial seizure with mesial temporal sclerosis has brought a resurgence of interest in studying the hippocampus. This article discusses arterial architecture of ...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章
doi:
更新日期:1997-02-01 00:00:00
abstract::In this article, the authors describe their strategy for intraoperative MR image guidance of tumor resection at low-field (0.2 T) strength. It is their opinion that intraoperative imaging is most useful in assessing the resection of intrinsic, infiltrating brain tumors; boundaries of the tumor cannot be clearly distin...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:2001-11-01 00:00:00
abstract::This content presents infectious and vascular spinal emergencies, including epidural abscess, nontraumatic epidural hematoma, vascular malformations, and spinal cord infarction. The spine is subjected to multiple potential insults, such as trauma, infection, ischemia, hemorrhage, tumor, inflammation, and degeneration....
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2010.07.006
更新日期:2010-11-01 00:00:00
abstract::Functional magnetic resonance imaging is able to define noninvasively the location of eloquent cortex responsible for speech, motor, and visual function, and it holds promise for localizing other important functional tissues in the future. Such localization is extremely important to the epileptologist and surgeon plan...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1995-11-01 00:00:00
abstract::The authors review the course and appearance of the major segments of the upper cranial nerves from their apparent origin at the brainstem through the proximal extraforaminal region, focusing on the imaging and anatomic features of particular relevance to high-resolution magnetic resonance imaging evaluation. Selected...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2013.03.021
更新日期:2014-02-01 00:00:00
abstract::Magnetic resonance and computed tomographic angiography have been increasingly applied to the study of disease affecting the cerebral vasculature. Despite these advances, however, conventional cerebral angiography clearly remains the diagnostic gold standard and essential guide to any microneurosurgical or endovascula...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1996-08-01 00:00:00
abstract::The role for neuroimaging in the management of patients with tremor is gradually increasing, particularly with respect to stereotactic neurosurgery and deep brain stimulation where less than 2-mm tolerance is required for accurate electrode placement. The routine use of single photon emission CT technology to image th...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章
doi:10.1016/j.nic.2009.08.005
更新日期:2010-02-01 00:00:00
abstract::EEG-fMRI is capable of providing novel localizing information in a substantial proportion of patients with frequent epileptiform discharges, even at 1.5T, suggesting a potential clinical role. Increasing availability of equipment capable of providing good-quality intra-MR imaging EEG with relative ease should ensure a...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2004.04.009
更新日期:2004-08-01 00:00:00
abstract::Previously, CT was considered insensitive in the evaluation of the acute ischemic stroke patient; however, more recently detection of early CT findings has proved to be of prognostic value in the evaluation of these patients. The use of CT coupled with early acute phase therapy of stroke such as thrombolytic therapy h...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1998-08-01 00:00:00
abstract::Conventional neuroimaging is still the mainstay in the assessment of the acute, follow-up, and chronic settings of concussion and mild traumatic brain injury (mTBI). Computed tomography (CT) is preferred for the initial assessment of acute mTBI, repeat evaluation in acute mTBI with neurologic deterioration, and cautio...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2017.09.006
更新日期:2018-02-01 00:00:00
abstract::Dynamic functional connectivity adds another dimension to resting-state functional MR imaging analysis. In recent years, dynamic functional connectivity has been increasingly used in resting-state functional MR imaging, and several studies have demonstrated that dynamic functional connectivity patterns correlate with ...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2020.09.004
更新日期:2021-02-01 00:00:00
abstract::Diskography has become a vital study in the evaluation of spinal pain, particularly in patients who are considered candidates for possible surgical intervention. It has been the author's experience that when diskography is performed with appropriate clinical indication by skilled and experienced practitioners who are ...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:2000-08-01 00:00:00
abstract::Extensive PET imaging research on AD has been conducted since PET scanners became available in the early 1980s. PET imaging using FDG, now commercially available, can detect early metabolic changes in AD and differential metabolic features of various dementing disorders. Image analysis techniques have also advanced in...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s1052-5149(03)00099-6
更新日期:2003-11-01 00:00:00
abstract::Assessment of the oxygenation status of brain tumors has been studied increasingly with imaging techniques in light of recent advances in oncology. Tumor oxygen tension is a critical factor influencing the effectiveness of radiation and chemotherapy and malignant progression. Hypoxic tumors are resistant to treatment,...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s1052-5149(02)00029-1
更新日期:2002-11-01 00:00:00
abstract::Cerebral blood flow (CBF, cerebral perfusion) mirrors cerebral metabolic demand and neuronal function, and therefore, is a vital parameter in the evaluation of pediatric brain injury and recovery. Until recently, measurement of CBF involved intravenous bolus injection of contrast agents or nuclear medicine methods tha...
journal_title:Neuroimaging clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.nic.2005.10.002
更新日期:2006-02-01 00:00:00