Abstract:
:Extensive PET imaging research on AD has been conducted since PET scanners became available in the early 1980s. PET imaging using FDG, now commercially available, can detect early metabolic changes in AD and differential metabolic features of various dementing disorders. Image analysis techniques have also advanced in the field of functional brain imaging and permit accurate and consistent scan interpretation. PET studies that involve autopsy-confirmed cases suggest that the PET diagnosis of AD is no worse or may even be better than clinical diagnosis. Limited prospective studies demonstrated the effects of PET imaging in dementia management, which precludes the approval of FDG PET for more widespread, reimbursable use. Further evidence for the efficacy of PET imaging through well-organized clinical studies, as well as continuing efforts in technologic development and basic research to characterize functional alterations in dementing disorders in living patients, are equally important to achieve the goal of better dementia care.
journal_name
Neuroimaging Clin N Amjournal_title
Neuroimaging clinics of North Americaauthors
Minoshima Sdoi
10.1016/s1052-5149(03)00099-6keywords:
subject
Has Abstractpub_date
2003-11-01 00:00:00pages
769-80issue
4eissn
1052-5149issn
1557-9867pii
S1052-5149(03)00099-6journal_volume
13pub_type
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journal_title:Neuroimaging clinics of North America
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journal_title:Neuroimaging clinics of North America
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