Pediatric perfusion MR imaging using arterial spin labeling.

Abstract:

:Cerebral blood flow (CBF, cerebral perfusion) mirrors cerebral metabolic demand and neuronal function, and therefore, is a vital parameter in the evaluation of pediatric brain injury and recovery. Until recently, measurement of CBF involved intravenous bolus injection of contrast agents or nuclear medicine methods that were technically difficult or ethically problematic in pediatrics. The development of arterial spin label (ASL) perfusion MR imaging as a noninvasive method for measuring CBF allows for the increased ability to measure this vital physiologic parameter in any age group. This article presents the technical aspects of performing ASL perfusion MR imaging in pediatrics, and discusses its current use in clinical studies and its potential for influencing important management strategies in specific disease entities.

journal_name

Neuroimaging Clin N Am

authors

Wang J,Licht DJ

doi

10.1016/j.nic.2005.10.002

keywords:

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

149-67, ix

issue

1

eissn

1052-5149

issn

1557-9867

pii

S1052-5149(05)00110-3

journal_volume

16

pub_type

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