Effect of c-Met inhibitor SU11274 on human colon cancer cell growth.

abstract：BACKGROUND:The aim of this research was to analyze the perioperative factors of regular hepatectomy and irregular hepatectomy. The superiority of the clinical application of the two methods was compared in the perioperative period. METHODS:From 1986 to 2011, 1798 patients underwent consecutive liver resections with re...

journal_title：Chinese medical journal

authors： Feng Z,Li H,Zhang J,Xu L,Xiao M,Huang Z,Zhang H

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The continual and rapid development of techniques which are used for diagnosis and treatment makes management of colorectal cancer more difficult depending on single discipline. Colorectal cancer multidisciplinary team (MDT) working model is recommended by UK and other countries, but there is little informat...

journal_title：Chinese medical journal

authors： Ye YJ,Shen ZL,Sun XT,Wang ZF,Shen DH,Liu HJ,Zhang WL,Chen YL,Zhou J,Poston GJ,Wang S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Prediabetes is an early stage of β-cell dysfunction presenting as insulin resistance. Evidences suggest that endoplasmic reticulum (ER) stress is involved in the pathogenesis of type 2 diabetes mellitus and prediabetes. In a Chinese population with prediabetes, we investigated single nucleotide polymorphisms...

journal_title：Chinese medical journal

authors： Feng N,Ma X,Wei X,Zhang J,Dong A,Jin M,Zhang H,Guo X

更新日期：2014-01-01 00:00:00

abstract：:By employing monoclonal phosphorylated neurofilaments antibody, we studied the abnormally pale-staining neurons in 3 cases of corticonigral degeneration by the avidin-biotin immunoperoxidase method. For comparison, the central chromatolysis in anterior horn cells secondary to cervical spine fracture and "ballooned" ne...

journal_title：Chinese medical journal

authors： Wang LN,Kowall NW,Richardson EP Jr

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:To determine the in vitro expression of interleukin-12 (IL-12) and its effect on signal transducers and activators of transcription (STAT) signaling molecules in peripheral blood mononuclear cells (PBMCs) in patients with systemic lupus erythematosus (SLE). METHODS:Peripheral blood mononuclear cells in 39 pa...

journal_title：Chinese medical journal

authors： Li Z,Li Y,Huang L,Xu H,Yu X,Ye R

更新日期：2002-06-01 00:00:00

abstract：:Myocardial revascularization by Nd: YAG laser used in rats with myocardial infarction was studied. The left coronary artery was ligated and the laser channels with a diameter of 300 microns were made immediately by 2.5-4.2 W lasersonics YAG unit. After 24 hours, the rats were killed. Evaluation included hemodynamics, ...

journal_title：Chinese medical journal

authors： Guo JX,Pan J,Ma L,Chen MZ,Xu H,Shi AY

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Hemophilia A (HA) is an X-linked inherited bleeding disorder caused by decreased activity of factor VIII (FVIII) due to heterogenous mutations in the FVIII coding gene (F8). The type of mutation plays an important role in the FVIII inhibitor formation. To date, several studies on the spectra of F8 defects ha...

journal_title：Chinese medical journal

authors： Hua BL,Yan ZY,Liang Y,Yan M,Fan LK,Li KX,Xiao B,Liu JZ,Zhao YQ

更新日期：2010-02-05 00:00:00

abstract：BACKGROUND:It is now recognized that Cimicifuga foetida (C. foetida) extract is effective in alleviating menopausal symptoms. But the durations reported were usually short. The aim of this study was to investigate the effects of C. foetida extract therapy and different estrogen and progesterone sequential therapies, on...

journal_title：Chinese medical journal

authors： Gaowa S,Sun AJ,Jiang Y,He FW,Zheng TP,Wang YP

更新日期：2015-04-20 00:00:00

abstract：OBJECTIVE:To analyze the effect and mechanism of hyperbaric oxygen (HBO) treatment for severe brain injury (SBI). METHODS:Fifty-five patients were divided into a treatment group of 35 patients and a control group of 20 patients. We observed the alterations of clinical, brain electric earth map (BEAM), endothelin (ET) ...

journal_title：Chinese medical journal

authors： Ren H,Wang W,Ge Z,Zhang J

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Metformin is the most widely used anti-diabetic drug in the world. An increasing body of evidence shows metformin also blocks cell cycle progression and selectively induces apoptosis via caspase activation in some breast tumor cells. Diffusion-weighted imaging (DWI) and bioluminescence imaging (BLI) have gre...

journal_title：Chinese medical journal

authors： Mao Y,Xia R,Wang L,Wang YQ,Gao FB

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Recent studies have demonstrated that the Lenke system is relatively efficient and consistent in classifying scoliosis curves. Basically, fusion should include the main curve and the structural minor curve. The criteria for defining the structural minor curve were established to help guide these decision-mak...

journal_title：Chinese medical journal

authors： Chen ZQ,Zhao YF,He SS,Wang CF,Zhang JT,Zhao YC,Yang CW,Li M

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Airway mucus hypersecretion is an important pathophysiological feature of chronic obstructive pulmonary disease, which is closely associated with cigarette smoking. However, the signal transduction pathway from the cell surface to the nucleus through which cigarette smoke causes upregulation of mucin gene ex...

journal_title：Chinese medical journal

authors： Xiao J,Wang K,Feng YL,Chen XR,Xu D,Zhang MK

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:Secreted modular calcium-binding proteins (SMOCs) are extracellular glycoproteins of the secreted protein, acidic, and rich in cysteine-related modular calcium-binding protein family and include two isoforms, SMOC1 and SMOC2, in humans. Functionally, SMOCs bind to calcium for various cell functions. In this r...

journal_title：Chinese medical journal

authors： Gao Q,Mok HP,Zhuang J

更新日期：2019-10-20 00:00:00

abstract：BACKGROUND:Na + /Ca 2+ exchanger (NCX) plays a crucial role in pentylenetetrazol-induced convulsion. However, it is unclear whether NCX is critically involved in hyperthermia-induced convulsion. In this study, we examined the potential changes in NCX3 in the hippocampus and cerebrocortex of rats with hyperthermia-induc...

journal_title：Chinese medical journal

authors： Sun D,Xiao JH,Bai Y,Chen MS,Hu JS,Wu GF,Mao B,Wu SH,Hu Y

更新日期：2015-11-20 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic inflammatory skin disease, affecting about 0.6% of the Chinese population. Many patients are not well controlled by conventional treatments, thus there is need for new treatment regimens. In this study, we assessed the efficacy and safety of secukinumab in Chinese patients with moderat...

journal_title：Chinese medical journal

authors： Cai L,Zhang JZ,Yao X,Gu J,Liu QZ,Zheng M,Zhang SF,Xu JH,Li CX,Cheng H,Guo Q,Pan WL,Li SQ,Li RY,Guo ZP,Song ZQ,Li SS,Dong XQ,Wang L,Fu R,Regnault P,Charef P,Mazur R,Patekar M

更新日期：2020-11-20 00:00:00

abstract：OBJECTIVE:To determine the relationships of Met416Val and XbaI polymorphism of muscle glycogen synthase (GYS1) gene and Trg64Arg variant of the beta(3)-adrenergic-receptor (beta(3)-AR) gene with type 2 diabetes mellitus (DM) and its intermediate phenotypes in the Chinese population. METHODS:Polymerase chain reaction-o...

journal_title：Chinese medical journal

authors： Wang G,Li Q,Niu T,Chen C,Xu X

更新日期：2002-09-01 00:00:00

abstract：:[This corrects the article DOI: 10.4103/0366-6999.181956.]. ...

journal_title：Chinese medical journal

authors：

更新日期：2016-07-20 00:00:00

abstract：BACKGROUND:Studies have reported that low bone mineral density (BMD) is prevalent in human immunodeficiency virus (HIV)-infected patients; however, the factors that contribute to HIV-related BMD changes are yet to be fully understood. Due to the application of dual X-ray absorptiometry (DXA) among a select group of hos...

journal_title：Chinese medical journal

authors： Zeng YQ,Xiao J,Li CL,Wang Y,Zhang L,Pang XL,Wang D,Du J,Zhao HX

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:The postremission therapies for adult patients generally contain consolidation chemotherapy, allogeneic hematopoietic stem cell transplantation and autologous hematopoietic stem cell transplantation (auto-HSCT). Because of the various results from different centers, the optimal therapy for adult acute lympho...

journal_title：Chinese medical journal

authors： Ding Z,Han MZ,Chen SL,Ma QL,Wei JL,Pang AM,Zhang XY,Liang C,Yao JF,Cao YG,Feng SZ,Jiang EL

更新日期：2015-08-05 00:00:00

abstract：BACKGROUND:The endovascular treatment of abdominal aortic aneurysm (AAA) has improved greatly in the last 15 years. The present study aimed to evaluate the endografting experience for the treatment of unfavorable abdominal aortic aneurysm (uAAA). METHODS:During December 2001 and December 2007, 41 patients with uAAA we...

journal_title：Chinese medical journal

authors： Hu ZJ,Chang GQ,Li XX,Huang XL,Yin HH,Wang SM

更新日期：2009-04-05 00:00:00

abstract：OBJECTIVE:To investigate the feasibility of adrenal sparing surgery for selected renal cell carcinoma (RCC), since the necessity of routine adrenalectomy during radical nephrectomy for RCC has been challenged in recent years. METHODS:178 patients underwent perifascial nephrectomy in a 16-year period. Of these patients...

journal_title：Chinese medical journal

authors： Xu C,Niu Z,Lü J,Wang J

更新日期：1998-10-01 00:00:00

abstract：:The association of gluckinase (GCK) gene with type 2 (non-insulin-dependent) diabetes mellitus was investigated in 168 Chinese subjects (85 unrelated type 2 diabetics and 83 non-diabetic controls). The microsatellite polymorphism marker, GCK-5', was amplified with polymerase chain reaction. Four alleles were observed ...

journal_title：Chinese medical journal

authors： Xiang K,Wu S,Wang Y,Sun D,Zhang R,Xu J,Huang Q,Karam JH,Bell GI

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:HATCH score is an established predictor of progression from paroxysmal to persistent atrial fibrillation (AF). The purpose of this study was to determine if HATCH score could predict recurrence after catheter ablation of AF. METHODS:The data of 488 consecutive paroxysmal AF patients who underwent an index c...

journal_title：Chinese medical journal

authors： Tang RB,Dong JZ,Long DY,Yu RH,Ning M,Jiang CX,Sang CH,Liu XH,Ma CS

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Exposure of adult mice to more than 95% O(2) produces a lethal injury by 72 hours. Nitric oxide synthase (NOS) is thought to contribute to the pathophysiology of murine hyperoxia-induced acute lung injury (ALI). Osteopontin (OPN) is a phosphorylated glycoprotein produced principally by macrophages. OPN inhib...

journal_title：Chinese medical journal

authors： Zhang XF,Liu S,Zhou YJ,Zhu GF,Foda HD

更新日期：2010-04-05 00:00:00

abstract：BACKGROUND:Apoptosis is a major cause of ischemic heart dysfunction. Apelin, the endogenous ligand for the G-protein-coupled APJ receptor, has been reported to exert cardioprotective effects during myocardial injury. The aim of this study was to investigate the effects of apelin on apoptosis of rat cardiomyocytes induc...

journal_title：Chinese medical journal

authors： Zhang Z,Yu B,Tao GZ

更新日期：2009-10-05 00:00:00

abstract：OBJECTIVE:To investigate the correlation among retinal fluorescein angiography, blood viscosity, and other factors in patients with open angle glaucoma (POAG). METHODS:Multiple step regression analysis was made to investigate the correlation between each of the following blood vessel filling times: the arm-choroid (A-...

journal_title：Chinese medical journal

authors： Liu X,Zhou W,Ye T,Ge J,Cai X,Cheng A,Lin Y,Liang L,Tang H,Chen Z

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:The side effects of cyclosporine therapy include thromboembolic complications. However, the mechanisms underlying the hypercoagulable state induced by cyclosporine are not fully understood. Cyclosporine binds to red blood cells (RBCs) with a high affinity in circulation and alters the membranes of RBCs. Ther...

journal_title：Chinese medical journal

authors： Zheng YN,Yu HJ,Hou JX,Lu CF,Zhou J

更新日期：2009-07-20 00:00:00

abstract：BACKGROUND:Since early December 2019, the 2019 novel coronavirus disease (COVID-19) has caused pneumonia epidemic in Wuhan, Hubei province of China. This study aimed to investigate the factors affecting the progression of pneumonia in COVID-19 patients. Associated results will be used to evaluate the prognosis and to f...

journal_title：Chinese medical journal

authors： Liu W,Tao ZW,Wang L,Yuan ML,Liu K,Zhou L,Wei S,Deng Y,Liu J,Liu HG,Yang M,Hu Y

更新日期：2020-05-05 00:00:00

abstract：:The surface structure of four different articular cartilages of the femoral head was studied with scanning electron microscope in 12 cases of hip joint osteoarthritis. These articular cartilages were mink white, yellow, dusky red and hyperplastic and thickened. The osteoarthritic articular cartilage surface was uneven...

journal_title：Chinese medical journal

authors： Chai BF,Tang XM

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:Clinical application of autologous fat grafting (AFG) is quickly expanding. Despite the widely acceptance, long-term survival rate (SR) of AFG remains a question not yet solved. Meanwhile, although rare, severe complications related to AFG including vision loss, stroke even death could be seen in the literatu...

journal_title：Chinese medical journal

authors： Yu NZ,Huang JZ,Zhang H,Wang Y,Wang XJ,Zhao R,Bai M,Long X

更新日期：2015-05-05 00:00:00