Updates in the management of high-grade glioma.

Abstract:

:The management of high-grade glioma (HGG) has evolved significantly over the last decade. Patients are managed in a multidisciplinary team setting in order to ensure their care is guided by the most current evidenced based treatments. The outcome in patients with HGG, while still poor, has improved in terms of both survival and quality of life during illness. This review discusses a number of developments seen in the management of HGG over the last 5 years.

journal_name

J Neurol

journal_title

Journal of neurology

authors

Bradley D,Rees J

doi

10.1007/s00415-013-7032-x

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

651-4

issue

4

eissn

0340-5354

issn

1432-1459

journal_volume

261

pub_type

杂志文章,评审
  • Abnormal ghrelin secretion contributes to gastrointestinal symptoms in multiple system atrophy patients.

    abstract::Patients with multiple system atrophy (MSA) often have evidence of compromised gastrointestinal motility. Ghrelin is a gut hormone that influences gastrointestinal motility in humans. The aim of this study was to determine whether ghrelin secretion is affected in MSA patients, and to investigate the relation between g...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-013-6944-9

    authors: Ozawa T,Tokunaga J,Arakawa M,Ishikawa A,Takeuchi R,Mezaki N,Miura T,Sakai N,Hokari M,Takeshima A,Utsumi K,Kondo T,Yokoseki A,Nishizawa M

    更新日期:2013-08-01 00:00:00

  • Parvalbumin-immunoreactive neurons in the cortex in Pick's disease.

    abstract::Parvalbumin (a calcium-binding protein)-immunoreactive (PV-Ir) neurons in the cerebral cortex were examined in 20 postmortem brains obtained from elderly controls and patients with Pick's disease (PD). The type of PV-Ir neurons and their distribution in control and PD brains were similar. The number of PV-Ir neurons i...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00314780

    authors: Arai H,Noguchi I,Makino Y,Kosaka K,Heizmann CW,Iizuka R

    更新日期:1991-07-01 00:00:00

  • Progression of sleep disturbances in Parkinson's disease: a 5-year longitudinal study.

    abstract:BACKGROUND:Sleep disorders can occur in early Parkinson's disease (PD). However, the relationship between different sleep disturbances and their longitudinal evolution has not been fully explored. OBJECTIVE:To describe the frequency, coexistence, and longitudinal change in excessive daytime sleepiness (EDS), insomnia,...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-020-10140-x

    authors: Xu Z,Anderson KN,Saffari SE,Lawson RA,Chaudhuri KR,Brooks D,Pavese N

    更新日期:2021-01-01 00:00:00

  • Peduncular hallucinosis: a syndrome of impaired reality monitoring.

    abstract::Peduncular hallucinosis (PH) is a syndrome of hallucinations and brainstem symptoms which has only been described in single case reports. A detailed analysis of five patients was undertaken to investigate the clincial characteristics, hallucinations and behavioural abnormalities of PH in greater detail. Frequent clini...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-0060-0254-4

    authors: Benke T

    更新日期:2006-12-01 00:00:00

  • The effect of mild microembolic injury on the energy metabolism of the cat brain.

    abstract::Moderate unilateral cerebral ischemia was produced by microembolism in 24 adult cats. Two million plastic microspheres with a diameter of 15 +/- 5 microns were injected into the left common carotid artery via the lingual artery. The physiological and metabolic responses to embolism were accessed by electrocorticograp...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00313342

    authors: Sugi T,Schuier FJ,Hossmann KA,Zülch KJ

    更新日期:1980-01-01 00:00:00

  • Comparison of preseptal and pretarsal injections of botulinum toxin in the treatment of blepharospasm and hemifacial spasm.

    abstract::Although the beneficial effect of subcutaneous injections of botulinum toxin type A (BTX-A) is well known in both blepharospasm and hemifacial spasm, the position of the injection sites around the orbicularis oculi may influence the effectiveness and side effects. Here we report results of preseptal and pretarsal BTX-...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/pl00007849

    authors: Cakmur R,Ozturk V,Uzunel F,Donmez B,Idiman F

    更新日期:2002-01-01 00:00:00

  • Frequency of nocturnal sudden death in patients with multiple system atrophy.

    abstract::Sudden death has been reported in patients with multiple system atrophy (MSA), although the frequency of this event has not been well delineated. We investigated the frequency and potential causes of sudden death in patients with MSA. During the 5-year observation period, 10 of 45 patients with probable MSA died. The ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-008-0941-4

    authors: Shimohata T,Ozawa T,Nakayama H,Tomita M,Shinoda H,Nishizawa M

    更新日期:2008-10-01 00:00:00

  • Aphasia outcome: the interactions between initial severity, lesion size and location.

    abstract:OBJECTIVES:The outcome of aphasia at 3 months is variable in patients with moderate/severe stroke. The aim was to predict 3-month aphasia outcome using prediction models including initial severity in addition to the interaction between lesion size and location at the acute phase. METHODS:Patients with post-stroke apha...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-019-09259-3

    authors: Benghanem S,Rosso C,Arbizu C,Moulton E,Dormont D,Leger A,Pires C,Samson Y

    更新日期:2019-06-01 00:00:00

  • Intraventricular haemorrhage, CT and arteriographic findings in thirty-five patients.

    abstract::Thirty-five patients with intraventricular haemorrhage shown by CT underwent cerebral arteriography. In 15 patients arteriography showed an occlusion of a carotid or middle cerebral artery. Secondary bleeding into an infarction caused the intraventricular haemorrhage. All 15 patients were aged over 40 years. ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00313641

    authors: Cohn DF,Avrahami E

    更新日期:1983-01-01 00:00:00

  • Intravenous thrombolysis for ischemic stroke in the golden hour: propensity-matched analysis from the SITS-EAST registry.

    abstract::As there are scarce data regarding the outcomes of acute ischemic stroke (AIS) patients treated with intravenous thrombolysis (IVT) within 60 min from symptom onset ("golden hour"), we sought to compare outcomes between AIS patients treated within [GH(+)] and outside [GH(-)] the "golden hour" by analyzing propensity s...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-017-8461-8

    authors: Tsivgoulis G,Katsanos AH,Kadlecová P,Czlonkowska A,Kobayashi A,Brozman M,Švigelj V,Csiba L,Fekete K,Kõrv J,Demarin V,Vilionskis A,Jatuzis D,Krespi Y,Liantinioti C,Giannopoulos S,Mikulik R

    更新日期:2017-05-01 00:00:00

  • Acetylcholine-receptor-like protein from human thymoma associated with myasthenia gravis.

    abstract::Cobrotoxin-binding protein was isolated by affinity chromatography from human thymoma which had been surgically removed from patients with myasthenia gravis. The protein was composed of polypeptides with a molecular mass of 40, 51, 65, and 74 kilodaltons as determined by polyacrylamide gel electrophoresis in the prese...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00618251

    authors: Kawanami S,Kamei H,Oita J,Kurokawa M,Uchida Y,Hayashi K

    更新日期:1987-05-01 00:00:00

  • Primary lateral sclerosis and the amyotrophic lateral sclerosis-frontotemporal dementia spectrum.

    abstract:AIM:To investigate whether primary lateral sclerosis (PLS) represents part of the amyotrophic lateral sclerosis-frontotemporal dementia (ALS-FTD) spectrum of diseases. METHODS:Comprehensive assessment was taken on 21 patients with PLS and results were compared to patients diagnosed with pure motor ALS (n = 27) and ALS...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-018-8917-5

    authors: Agarwal S,Highton-Williamson E,Caga J,Matamala JM,Dharmadasa T,Howells J,Zoing MC,Shibuya K,Geevasinga N,Vucic S,Hodges JR,Ahmed RM,Kiernan MC

    更新日期:2018-08-01 00:00:00

  • Long-term levodopa/carbidopa intestinal gel in advanced Parkinson's disease.

    abstract::The short-term benefits of levodopa/carbidopa intestinal gel (LCIG) in patients with advanced Parkinson's disease (PD) are well documented, but the long-term benefits are still uncertain. The aim of this study was to investigate the motor and cognitive outcome of LCIG treatment in advanced PD after a follow-up period ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-013-7235-1

    authors: Cáceres-Redondo MT,Carrillo F,Lama MJ,Huertas-Fernández I,Vargas-González L,Carballo M,Mir P

    更新日期:2014-03-01 00:00:00

  • Mitochondrial encephalomyopathy, lactic acidosis and stroke in adults: two cases.

    abstract::Two previously healthy women are described who in their late thirties suffered transient strokelike episodes, consisting of initial headache and vomiting, with various subsequent neurological signs that were only partially reversible. Investigations revealed elevated serum creatine kinase, lactic acidosis, hypertrigly...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00818708

    authors: Kremer HP,Keyser A,Wintzen AR,Scholte HR,van Hellenberg Hubar JG,Poorthuis BJ,Ruitenbeek W

    更新日期:1993-01-01 00:00:00

  • Prevalence of epilepsy in northeast Madrid.

    abstract::During a period of 42 months, we studied the prevalence of epilepsy in a specific health district, composing by four towns with 98,405 inhabitants older than 10 years. This has been accomplished by a two-phase cross-sectional study. The prevalence rate observed was 4.12/1000 inhabitants for all types of epilepsy. No s...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s004150170091

    authors: Luengo A,Parra J,Colás J,Rámos F,Carreras T,Fernández-Pozos MJ,Muñoz A,Hernando V

    更新日期:2001-09-01 00:00:00

  • Treatment of multiple sclerosis: current concepts and future perspectives.

    abstract::Currently, several disease-modifying therapies for the treatment of multiple sclerosis are established and more are likely to be introduced. These treatment options differ with respect to their application profile, mechanism of action, efficacy, safety, and tolerance. Here, we review current concepts of MS therapies, ...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-011-6101-2

    authors: Buck D,Hemmer B

    更新日期:2011-10-01 00:00:00

  • [Intracranial and spinal hemorrhage in haemophilia (author's transl)].

    abstract::Among 234 hemophiliacs, 14 patients (5.9%) with intracranial and 1 patient (0.4%) with intramedullary hemorrhage were observed and examined. The average age at the time of hemorrhage was 17 years in patients with severe hemophilia and 43 years in patients with moderate hemophilia. The patients with mild hemophilia and...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00313358

    authors: Mamoli B,Sonneck G,Lechner K

    更新日期:1976-01-14 00:00:00

  • Movement disorder emergencies.

    abstract::Movement disorder emergencies include any movement disorder which evolves over hours to days, in which failure to appropriately diagnose and manage can result in patient morbidity or mortality. It is crucial that doctors recognize these emergencies with accuracy and speed by obtaining the proper history and by being f...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-008-4002-9

    authors: Poston KL,Frucht SJ

    更新日期:2008-08-01 00:00:00

  • Neurological complications following rubella infection.

    abstract::Neurological complications following rubella are only rarely encountered. However, in many cases severe neurological impairment may occur, leading to permanent disability. In a recent epidemic of rubella in Israel during the years 1978-1979, 20 patients with severe neurological complications have been seen. We report ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00313402

    authors: Bechar M,Davidovich S,Goldhammer G,Machtey I,Gadoth N

    更新日期:1982-01-01 00:00:00

  • Predictors of outcome in HSV encephalitis.

    abstract::This study aims to explore the clinical features, radiological findings, management and the factors influencing prognosis in PCR-confirmed herpes simplex virus encephalitis (HSE). This is a retrospective review of consecutive patients diagnosed with HSE at Mayo Clinic, Rochester, MN, between January 1995 and December ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-015-7960-8

    authors: Singh TD,Fugate JE,Hocker S,Wijdicks EFM,Aksamit AJ Jr,Rabinstein AA

    更新日期:2016-02-01 00:00:00

  • The impact of the initial severity on later outcome: retrospective analysis of a large cohort of botulinum toxin naïve patients with idiopathic cervical dystonia.

    abstract:BACKGROUND:The aim of study was to demonstrate that the first three injections of botulinum neurotoxin type A (BoNT/A) appear to be less effective in botulinum toxin naïve patients with idiopathic cervical dystonia (CD) with mild symptoms and low severity scores (TSUI-scores) at onset of BoNT/A-therapy compared to pati...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-020-10128-7

    authors: Hefter H,Samadzazeh S,Rosenthal D

    更新日期:2021-01-01 00:00:00

  • Three-dimensional topographic analysis of spinal accessory motoneurons under chronic mechanical compression: an experimental study in the mouse.

    abstract::We investigated the effect of chronic mechanical compression of the cervical spinal cord on the number of spinal accessory motoneurons in 25 tiptoe-walking Yoshimura mice. The animals had calcified deposits in the atlantoaxial membrane at the C1-C2 vertebral level, compressing the spinal cord posterolaterally. Motoneu...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s004150050076

    authors: Baba H,Maezawa Y,Uchida K,Imura S,Kawahara N,Tomita K,Kudo M

    更新日期:1997-04-01 00:00:00

  • Botulinum toxin therapy for treatment of spasticity in multiple sclerosis: review and recommendations of the IAB-Interdisciplinary Working Group for Movement Disorders task force.

    abstract::Botulinum toxin (BT) therapy is an established treatment of spasticity due to stroke. For multiple sclerosis (MS) spasticity this is not the case. IAB-Interdisciplinary Working Group for Movement Disorders formed a task force to explore the use of BT therapy for treatment of MS spasticity. A formalised PubMed literatu...

    journal_title:Journal of neurology

    pub_type: 指南,杂志文章,评审

    doi:10.1007/s00415-016-8304-z

    authors: Dressler D,Bhidayasiri R,Bohlega S,Chahidi A,Chung TM,Ebke M,Jacinto LJ,Kaji R,Koçer S,Kanovsky P,Micheli F,Orlova O,Paus S,Pirtosek Z,Relja M,Rosales RL,Sagástegui-Rodríguez JA,Schoenle PW,Shahidi GA,Timerbaeva S,

    更新日期:2017-01-01 00:00:00

  • Deterioration of dopaminergic pathways and alterations in cognition and motor functions.

    abstract::Degeneration of central dopaminergic neurons is the most characteristic pathological feature of Parkinson's disease. It remains to be established to what extent these lesions explain the motor, cognitive and affective disorders observed in patients, but there are now some interesting clues to a possible solution. ...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/BF00819560

    authors: Dubois B,Pillon B,Agid Y

    更新日期:1992-01-01 00:00:00

  • Epidemiology of paraneoplastic neurological syndromes: a population-based study.

    abstract:BACKGROUND:The epidemiology of paraneoplastic neurological syndromes (PNS) remains to be defined. We present here the first population-based incidence study and report the clinical spectrum and antibody profile of PNS in a large area in Northeastern Italy. METHODS:We performed a 9-year (2009-2017) population-based epi...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-019-09544-1

    authors: Vogrig A,Gigli GL,Segatti S,Corazza E,Marini A,Bernardini A,Valent F,Fabris M,Curcio F,Brigo F,Iacono D,Passadore P,Rana M,Honnorat J,Valente M

    更新日期:2020-01-01 00:00:00

  • Determinants of autonomic dysfunction in idiopathic Parkinson's disease.

    abstract:OBJECTIVES:To determine demographic or disease-related factors that may influence the severity of autonomic dysfunction in idiopathic Parkinson's disease (IPD). METHODS:532 patients with IPD aged between 55 and 75 years were included. Severity of autonomic dysfunction was assessed using a 9-item autonomic dysfunction ...

    journal_title:Journal of neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00415-005-0909-6

    authors: Korchounov A,Kessler KR,Yakhno NN,Damulin IV,Schipper HI

    更新日期:2005-12-01 00:00:00

  • From amaurosis fugax to asymptomatic bithalamic infarct.

    abstract::Bilateral paramedian thalamic infarctions are usually associated with impaired consciousness, oculomotor disturbances and neuropsychological changes. A 44-year-old healthy woman presented with amaurosis fugax of the right eye immediately after a Valsalva maneuver. Neurological examination, in particular visual acuity,...

    journal_title:Journal of neurology

    pub_type: 信件

    doi:10.1007/s00415-009-5030-9

    authors: Emond H,Landis T,Perren F

    更新日期:2009-06-01 00:00:00

  • When is there a full recovery for a myasthenia gravis patient?

    abstract::A myasthenia gravis (MG) patient who seems to have recovered can later have recurrence of myasthenic signs. Clearly clinical remission does not always correspond to the normalization of all the factors involved in the pathogenesis of the disease. In ten patients who had apparently recovered from MG, electromyographic ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00313771

    authors: Scoppetta C,Bartoccioni E,David P,Flamini G,Lo Monaco M,Scuderi F,Tonali P

    更新日期:1982-01-01 00:00:00

  • Differentiating Alzheimer's disease from subcortical vascular dementia with the FAB test.

    abstract:BACKGROUND:The frontal assessment battery (FAB) test is a composite tool for assessing executive functions related to the frontal lobe. Neuropsychological and blood-flow studies indicate distinct patterns of deterioration of anterior and posterior cortical function in Alzheimer's disease (AD) and subcortical vascular d...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-006-0251-7

    authors: Oguro H,Yamaguchi S,Abe S,Ishida Y,Bokura H,Kobayashi S

    更新日期:2006-11-01 00:00:00

  • Bulbocavernosus reflex latencies and somatosensory evoked potentials after pudendal nerve stimulation in the diagnosis of impotence.

    abstract::The bulbocavernosus reflex (BCR) was examined in 39 normal potent men and in 252 patients with impaired potency of varying aetiology. For BCR evaluation minimum, maximum and mean latencies, the temporal dispersion in ten successive responses, together with minimum and maximum side differences from simultaneous recordi...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00314350

    authors: Tackmann W,Porst H,van Ahlen H

    更新日期:1988-03-01 00:00:00