Abstract：
:We investigated the effect of chronic mechanical compression of the cervical spinal cord on the number of spinal accessory motoneurons in 25 tiptoe-walking Yoshimura mice. The animals had calcified deposits in the atlantoaxial membrane at the C1-C2 vertebral level, compressing the spinal cord posterolaterally. Motoneurons of the spinal accessory nerve between C1 and C5 segments were labelled using wheat germ agglutinin-horseradish peroxidase (WGA-HRP) injected into the sternocleidomastoid muscles. The counted cells were processed into a three-dimensional computer display to analyse the cytoarchitectonic changes caused by external cord compression. The number of WGA-HRP-labelled spinal accessory motoneurons was significantly reduced on the affected side. The number of motoneurons in compromised C2 and C3 cord segments correlated linearly with the extent of mechanical compression, but no such relationship was present on the contralateral side. There was an increase in the number of WGA-HRP-labelled spinal accessory motoneurons in the medial cell pools of the anterior grey horn at a level most rostral to the compression, and in the ventrolateral cell pools at levels immediately rostral to the compression. Our findings suggest that the spinal accessory motoneurons translocate rostral to the area of external compression in order to avoid mechanical injury.
journal_name
J Neuroljournal_title
Journal of neurologyauthors
Baba H,Maezawa Y,Uchida K,Imura S,Kawahara N,Tomita K,Kudo Mdoi
10.1007/s004150050076subject
Has Abstractpub_date
1997-04-01 00:00:00pages
222-9issue
4eissn
0340-5354issn
1432-1459journal_volume
244pub_type
杂志文章abstract：OBJECTIVE:A growing number of studies have been conducted on the relationship between anger and hostility and the risk of stroke, and their conclusions are not consistent. Accordingly, we performed a meta-analysis to evaluate the relationship between anger and hostility and the risk of stroke. METHODS:We searched the ...
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pub_type： 杂志文章,meta分析,评审
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abstract：:The safety and efficacy of intravenous thrombolysis (IVT) in dissection-related ischemic stroke (DRIS) has not been established. We sought to determine safety and recovery rates of IVT in DRIS using prospective, international, multicenter data and by conducting a comprehensive meta-analysis of reported case series. We...
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pub_type： 杂志文章
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abstract：:There has been a resurgence in the use of functional neurosurgery for Parkinson's disease. An important factor that has played a role in this development is the recent understanding of the functional anatomy of the basal ganglia including a knowledge of the changes in the activities of neurons in the internal segment ...
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pub_type： 杂志文章,评审
doi：10.1007/BF03161079
更新日期：1999-09-01 00:00:00
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pub_type： 信件
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abstract：:Glucocorticoids are the standard of care for multiple sclerosis (MS) relapses, but the most desirable route of administration is still matter of debate. The aim of the study was to compare the efficacy and safety of oral versus intravenous steroids for treatment of acute relapses in patients with MS. Randomized or qua...
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pub_type： 杂志文章,meta分析,评审
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doi：10.1007/BF00900957
更新日期：1994-06-01 00:00:00
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pub_type： 临床试验,杂志文章
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更新日期：2001-02-01 00:00:00
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doi：10.1007/BF00314279
更新日期：1987-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s00415-004-0449-5
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pub_type： 杂志文章
doi：10.1007/BF00313346
更新日期：1980-01-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/BF00314359
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pub_type： 信件
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更新日期：2019-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2006-08-01 00:00:00
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pub_type： 杂志文章,多中心研究
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