Comparison of preseptal and pretarsal injections of botulinum toxin in the treatment of blepharospasm and hemifacial spasm.

abstract：:Temporal lobe epilepsy has been usually associated with progressive brain atrophy due to neuronal cell loss. However, recent animal models demonstrated a dual effect of epileptic seizures with initial enhancement of hippocampal neurogenesis followed by abnormal astrocyte proliferation and neurogenesis depletion in the...

journal_title：Journal of neurology

authors： Roggenhofer E,Santarnecchi E,Muller S,Kherif F,Wiest R,Seeck M,Draganski B

更新日期：2019-12-01 00:00:00

abstract：:The MS-ID (Multiple Sclerosis Information Dividend) project was initiated by the European Multiple Sclerosis Platform (EMSP) in 2007 in order to identify and address major inequalities of MS treatment and care and thus eliminate disparities across the EU. One major approach to reach these goals in the longer term is t...

journal_title：Journal of neurology

authors： Flachenecker P,Khil L,Bergmann S,Kowalewski M,Pascu I,Pérez-Miralles F,Sastre-Garriga J,Zwingers T

更新日期：2010-10-01 00:00:00

abstract：:The finding of a mutation in the alpha-synuclein gene in a rare autosomal dominant form of idiopathic Parkinson's disease (IPD), has prompted increased interest in identifying genes that account for the more common sporadic form. A number of association studies have suggested that functional polymorphisms in genes tha...

journal_title：Journal of neurology

authors： Bajaj NP,Shaw C,Warner T,RayChaudhuri K

更新日期：1998-10-01 00:00:00

abstract：:Erdheim-Chester disease (ECD) is a rare, non-Langerhans form of histiocytosis of unknown etiology that affects multiple organs. We report 6 cases of ECD with neurological involvement and neuroradiological abnormalities on brain MRI. A literature review revealed 60 other cases of ECD with neurological involvement. We t...

journal_title：Journal of neurology

authors： Lachenal F,Cotton F,Desmurs-Clavel H,Haroche J,Taillia H,Magy N,Hamidou M,Salvatierra J,Piette JC,Vital-Durand D,Rousset H

更新日期：2006-10-01 00:00:00

abstract：:Mutations in C19orf12 have been recently identified as the molecular genetic cause of a subtype of neurodegeneration with brain iron accumulation (NBIA). Given the mitochondrial localization of the gene product the new NBIA subtype was designated mitochondrial membrane protein-associated neurodegeneration. Frequent fe...

journal_title：Journal of neurology

authors： Deschauer M,Gaul C,Behrmann C,Prokisch H,Zierz S,Haack TB

更新日期：2012-11-01 00:00:00

abstract：:Small fibre neuropathy (SFN) has been demonstrated in sarcoidosis. However, a systematic analysis of neuropathic pain and autonomic symptoms, key features of SFN, has not been performed. Clinimetric evaluation of pain and autonomic symptoms using the neuropathic pain scale (NPS) and the modified Composite Autonomic Sy...

journal_title：Journal of neurology

authors： Bakkers M,Faber CG,Drent M,Hermans MC,van Nes SI,Lauria G,De Baets M,Merkies IS

更新日期：2010-12-01 00:00:00

abstract：:A 57-year-old male was repeatedly admitted to hospital because of complex neurological symptoms, including radicular pain, disturbance of micturition, seizures, and severely impaired mental state. The diagnosis was encephalomyeloradiculitis possibly of viral origin, and treatment with immunosuppressants was initiated....

journal_title：Journal of neurology

authors： Kollikowski HH,Schwendemann G,Schulz M,Wilhelm H,Lehmann HJ

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:An optimal management of vascular risk factors, associated with antithrombotic drugs and carotid surgery when appropriate, reduces the risk of a new vascular event after stroke. Although secondary prevention is not optimal in many patients in practice, the question of whether there is an improv...

journal_title：Journal of neurology

authors： Girot M,Mackowiak-Cordoliani MA,Deplanque D,Hénon H,Lucas C,Leys D

更新日期：2005-01-01 00:00:00

abstract：:Optic neuritis usually presents with rapid and gradual loss of vision that is either complete or incomplete, and typically associated with retro-orbital pain. To our knowledge there have been no documented reports of optic neuritis presenting with multiple episodes of amaurosis fugax, the sudden and transient loss of ...

journal_title：Journal of neurology

authors： Awad AM,Estephan B,Warnack W,Stüve O

更新日期：2009-12-01 00:00:00

abstract：:The long-duration response (LDR) to levodopa is an important component of the therapeutic response to the drug in Parkinson's disease (PD). Some characteristics are peculiar: it is independent from peripheral pharmacokinetics of levodopa, but it is dependent on the intervals between doses and on the size of each dose....

journal_title：Journal of neurology

authors： Zappia M,Nicoletti A

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVES:Recent retrospective studies found sleep disorders, including obstructive sleep apnea and its symptoms to occur more often in patients following aneurysmal subarachnoid hemorrhage, but studies investigating the incidence of subarachnoid hemorrhage in patients with diagnosed obstructive sleep apnea [OSA] comp...

journal_title：Journal of neurology

authors： Zaremba S,Albus L,Schuss P,Vatter H,Klockgether T,Güresir E

更新日期：2019-06-01 00:00:00

abstract：:Disability in multiple sclerosis (MS) patients is associated with white matter (WM) and gray matter (GM) pathology, and both processes contribute differently over the disease course. Total and regional GM volume loss can be imaged via voxel-based morphometry (VBM). Here, we retrospectively analyzed a group of 213 MS p...

journal_title：Journal of neurology

authors： Grothe M,Lotze M,Langner S,Dressel A

更新日期：2016-06-01 00:00:00

abstract：:Using a novel trial design, we prospectively examined the effect of intravenous immunoglobulin in seven patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in a double-blind, placebo-controlled cross-over study. We suggest that the commonly used manual muscle testing and Rankin scale are not...

journal_title：Journal of neurology

authors： Thompson N,Choudhary P,Hughes RA,Quinlivan RM

更新日期：1996-03-01 00:00:00

abstract：:Isolated floccular infarction is extremely rare, and impairments of the vestibulo-ocular reflex (VOR) have not been explored in humans with isolated floccular lesions. The purpose of this study was to examine and report selective impairment of VOR in response to high acceleration using head impulse in a patient with i...

journal_title：Journal of neurology

authors： Park HK,Kim JS,Strupp M,Zee DS

更新日期：2013-06-01 00:00:00

abstract：:The emotional and relationship problems associated with MS have not always been fully appreciated by the medical profession, which has tended to concentrate on the physical aspects of this disease. Yet the psychological problems of MS often cause more suffering than physical effects. ...

journal_title：Journal of neurology

authors： Kesselring J,Klement U

更新日期：2001-03-01 00:00:00

abstract：:To investigate the role of endogenous opioid peptides in the pathophysiology of cerebral ischaemia, the CSF levels of immunoreactive beta-endorphin and leu-enkephalin in 16 patients with cerebral infarction were measured. Both the CSF beta-endorphin and leu-enkephalin levels in the acute stage of cerebral infarction w...

journal_title：Journal of neurology

authors： Kobari M,Ishihara N,Yunoki K

更新日期：1987-06-01 00:00:00

abstract：:Leukoencephalopathy with brainstem and spinal cord involvement and elevated lactate (LBSL) is a rare, autosomal recessive disorder caused by mutations in the gene encoding a mitochondrial aspartyl-tRNA synthetase, DARS2. The disease is characterized by progressive spastic ataxia and magnetic resonance imaging (MRI) sh...

journal_title：Journal of neurology

authors： Tzoulis C,Tran GT,Gjerde IO,Aasly J,Neckelmann G,Rydland J,Varga V,Wadel-Andersen P,Bindoff LA

更新日期：2012-02-01 00:00:00

abstract：:To define the incidence and type of neurological complications and associated factors, we reviewed 41 consecutive patients who had 45 procedures for liver transplantation. Encephalopathy occurred after 28 procedures (62%) with immediate onset and no significant recovery before death or re-transplantation in 11 (24%), ...

journal_title：Journal of neurology

authors： Ghaus N,Bohlega S,Rezeig M

更新日期：2001-12-01 00:00:00

abstract：:The short-term benefits of levodopa/carbidopa intestinal gel (LCIG) in patients with advanced Parkinson's disease (PD) are well documented, but the long-term benefits are still uncertain. The aim of this study was to investigate the motor and cognitive outcome of LCIG treatment in advanced PD after a follow-up period ...

journal_title：Journal of neurology

authors： Cáceres-Redondo MT,Carrillo F,Lama MJ,Huertas-Fernández I,Vargas-González L,Carballo M,Mir P

更新日期：2014-03-01 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disease caused by both genetic and environmental factors. Sirtuins are highly-conserved, NAD-dependent class III deacetylases that regulate a variety of cellular functions. Most of the known sirtuins have been involved in animal models of neurodegenerative disorders, suc...

journal_title：Journal of neurology

authors： Jesús S,Gómez-Garre P,Carrillo F,Cáceres-Redondo MT,Huertas-Fernández I,Bernal-Bernal I,Bonilla-Toribio M,Vargas-González L,Carballo M,Mir P

更新日期：2013-09-01 00:00:00

abstract：:Quality of Life (QoL) is the preferred outcome in non-pharmacological trials, but there is little UK population evidence of QoL in epilepsy. In advance of evaluating an epilepsy self-management course we aimed to describe, among UK participants, what clinical and psycho-social characteristics are associated with QoL. ...

journal_title：Journal of neurology

authors： Ridsdale L,Wojewodka G,Robinson E,Landau S,Noble A,Taylor S,Richardson M,Baker G,Goldstein LH,SMILE Team.

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Since the detection of autoantibodies against neuronal surface antigens, autoimmune encephalitis (AE) has been more frequently diagnosed, especially in patients with symptoms typical of limbic encephalitis, such as seizures, short-term memory deficits, or psychosis. However, the clinical spectrum of AE may b...

journal_title：Journal of neurology

authors： Baumgartner A,Rauer S,Hottenrott T,Leypoldt F,Ufer F,Hegen H,Prüss H,Lewerenz J,Deisenhammer F,Stich O

更新日期：2019-01-01 00:00:00

abstract：:Anti-N-Methyl-D-Aspartate receptor (NMDAR) encephalitis is an acute neurological disorder affecting children and adults. We aimed to compare the clinical characteristics, treatments, and outcomes between children and adults with anti-NMDAR encephalitis and to assess the probable risk factors. In this observational stu...

journal_title：Journal of neurology

authors： Huang Q,Wu Y,Qin R,Wei X,Ma M

更新日期：2016-12-01 00:00:00

abstract：:Five patients are described who developed unilateral narrowing of the palpebral fissure that was aggravated by smiling. They had ischaemic lesions involving mainly the contralateral lenticulocapsular area. This rare but distinct symptom may be an action induced focal eyelid dystonia, and could be described as'smile-wi...

journal_title：Journal of neurology

authors： Kim JS

更新日期：2001-05-01 00:00:00

abstract：:Cerebral atrophy calculated from serial MRI is a marker of Alzheimer's disease (AD) progression, and a potential outcome measure for therapeutic trials. Reducing within-subject variability in cerebral atrophy rates by acquiring more than two serial scans could allow for shorter clinical trials requiring smaller patien...

journal_title：Journal of neurology

authors： Schott JM,Frost C,Whitwell JL,Macmanus DG,Boyes RG,Rossor MN,Fox NC

更新日期：2006-09-01 00:00:00

abstract：:The CHA(2)DS(2)-VASc score was developed to improve stroke risk stratification in atrial fibrillation (AF) patients. We sought to analyze the distribution and prognostic value of the CHA(2)DS(2)-VASc score in a cohort of ischemic stroke patients with AF. In total, 439 consecutive stroke patients with AF were studied. ...

journal_title：Journal of neurology

authors： Giralt-Steinhauer E,Cuadrado-Godia E,Ois Á,Jiménez-Conde J,Rodríguez-Campello A,Planellas L,Jimena-García S,Rubio MÁ,Roquer-González J

更新日期：2012-04-01 00:00:00

abstract：:Thirteen patients with subacute sclerosing panencephalitis (S.S.P.E.) at different stages of the disease were admitted for transfer factor treatment. The transfer factor was prepared from non-selected blood bank donors. The activity of the transfer factor was tested in patients with diseases other than S.S.P.E. and wa...

journal_title：Journal of neurology

authors： Käckell YM,Grob PJ,Kreth WH,Kibler R,Meulen V

更新日期：1975-12-02 00:00:00

abstract：:We reviewed the records of all patients who had received an epidural catheter for management of chronic cancer pain in a 3-year period (1993-1996). Patients with nervous system infections were identified, and pertinent clinical, radiological (magnetic resonance imaging), and bacteriological data were analyzed. We iden...

journal_title：Journal of neurology

authors： Sillevis Smitt P,Tsafka A,van den Bent M,de Bruin H,Hendriks W,Vecht C,Teng-van de Zande F

更新日期：1999-09-01 00:00:00

abstract：:Natalizumab (TYSABRI(®)), a specific α4-integrin antagonist, is approved as a second-line treatment of relapsing-remitting MS (RRMS) patients who fail therapy with interferons or as first-line treatment of patients with highly active relapsing-remitting disease. Since the market introduction of natalizumab as a monoth...

journal_title：Journal of neurology

authors： Hellwig K,Gold R

更新日期：2011-11-01 00:00:00

abstract：:An 18-year-old man suffered from acute Sydenham chorea appearing coincidently with beta-haemolytic streptococcal throat infection. Imaging techniques documented lesions of basal ganglia and substantia nigra. In the early course of the disease vascular lesions may be important pathogenetic mechanisms of this acquired m...

journal_title：Journal of neurology

authors： Heye N,Jergas M,Hötzinger H,Farahati J,Pöhlau D,Przuntek H

更新日期：1993-02-01 00:00:00