CSF beta-endorphin and leu-enkephalin levels in the acute and chronic stages of cerebral infarction.

abstract：:The neuropsychiatric symptoms and behavioral disorders affecting Parkinson's disease (PD) patients are common and disabling. A PD-specific interview-based 12-item scale, the Scale for Evaluation of Neuropsychiatric Disorders in Parkinson's Disease (SEND-PD), has been developed to assess the severity of neuropsychiatri...

journal_title：Journal of neurology

authors： Martinez-Martin P,Frades-Payo B,Agüera-Ortiz L,Ayuga-Martinez A

更新日期：2012-11-01 00:00:00

abstract：:The purpose of this study was to evaluate the contribution of posterior circulation to memory function by comparing memory scores between patients with and without a foetal-type posterior cerebral artery (FTP) during the intracarotid amobarbital procedure (IAP) in epilepsy patients. Patients undergoing bilateral IAP b...

journal_title：Journal of neurology

authors： Zijlmans M,Huibers CJ,Huiskamp GJ,de Kort GA,Alpherts WC,Leijten FS,Hendrikse J

更新日期：2012-08-01 00:00:00

abstract：:Production of reactive oxygen species after cerebral blood flow disruption may enhance tissue damage through multiple molecular pathways. Changes in nitric oxide (NO) metabolism and oxidative stress status were investigated in 47 patients with ischemic stroke by measuring plasma nitric oxide (NO) and peroxynitrite (ON...

journal_title：Journal of neurology

authors： Taffi R,Nanetti L,Mazzanti L,Bartolini M,Vignini A,Raffaelli F,Pasqualetti P,Vernieri F,Provinciali L,Silvestrini M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Elective programs for medical students in the last year of their university training are poorly evaluated. The goal of this study was to determine the gain in theoretical and practical skills in a group of students during their elective in neurology. Students were trained by either conventional teaching meth...

journal_title：Journal of neurology

authors： Heckmann JG,Bleh C,Dütsch M,Lang CJ,Neundörfer B

更新日期：2003-12-01 00:00:00

abstract：:This study aimed at an analysis of the release of Braintype and Heart-type Fatty Acid- Binding Proteins (B-FABP and HFABP) in acute ischaemic stroke and their potential value as neurobiochemical markers of brain damage. We investigated 42 consecutive patients admitted within 6 hours after ischaemic stroke. Serial veno...

journal_title：Journal of neurology

authors： Wunderlich MT,Hanhoff T,Goertler M,Spener F,Glatz JF,Wallesch CW,Pelsers MM

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:In order to define the predictors of prolonged survival available at the time of first examination we performed a historical cohort study of amyotrophis sclerosis (ALS) patients referred to our ALS Clinic over the last 20 years. METHODS:In a group of 1034 patients with the diagnosis of definite or probable A...

journal_title：Journal of neurology

authors： Czaplinski A,Yen AA,Appel SH

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:More research is needed to understand the contribution of comorbidities to MS symptomatology. OBJECTIVES:To examine the dose-response relationship between the number of comorbidities and severity of MS symptoms and to assess the relative contribution of comorbidity groups and individual comorbidities to the...

journal_title：Journal of neurology

authors： Lo LMP,Taylor BV,Winzenberg T,Palmer AJ,Blizzard L,van der Mei I

更新日期：2020-09-02 00:00:00

abstract：:Rapid-eye-movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by complex motor activity associated with dreaming during REM sleep. RBD may be idiopathic or associated with various neurological diseases involving the brainstem. The association of RBD and limbic system impairment was unclear. We r...

journal_title：Journal of neurology

authors： Lin FC,Liu CK,Hsu CY

更新日期：2009-07-01 00:00:00

abstract：:Atrial fibrillation (AF) is considered a predictor for severe stroke and poor outcome. The aim was to evaluate whether AF is associated with poor outcome in acute ischemic stroke (IS) patients treated with intravenous thrombolysis (IVT). In a retrospective study, 157 consecutive IS patients (98 males, mean age 67.3 +/...

journal_title：Journal of neurology

authors： Sanák D,Herzig R,Král M,Bártková A,Zapletalová J,Hutyra M,Skoloudík D,Vlachová I,Veverka T,Horák D,Kanovský P

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Protein Z (PZ), a vitamin Kdependent protein, plays a role in inhibiting coagulation. Its plasma level or PZ gene polymorphisms have been discussed as risk factors for stroke with conflicting results reported between various studies. Only one of these polymorphisms was studied in a cohort of pati...

journal_title：Journal of neurology

authors： Le Cam-Duchez V,Bagan-Triquenot A,Barbay V,Mihout B,Borg JY

更新日期：2008-10-01 00:00:00

abstract：:Glycogen storage disease type II (GSDII) is a lysosomal storage disorder caused by acid alpha-1,4-glucosidase deficiency and associated with recessive mutations in its coding gene GAA. Few studies have provided so far a detailed phenotypical characterization in late onset GSDII (LO-GSDII) patients. Genotype-phenotype ...

journal_title：Journal of neurology

authors： Remiche G,Ronchi D,Magri F,Lamperti C,Bordoni A,Moggio M,Bresolin N,Comi GP

更新日期：2014-01-01 00:00:00

abstract：:Acanthocytosis occurs because of ultrastructural abnormalities of the erythrocyte membranous skeleton resulting in reduced membrane fluidity. At least three hereditary neurological conditions are associated with it, although as yet the pathogenesis of the neurological features is unknown. In abetalipoproteinaemia, an ...

journal_title：Journal of neurology

authors： Stevenson VL,Hardie RJ

更新日期：2001-02-01 00:00:00

abstract：INTRODUCTION:The so called "neurodegenerative Langerhans cell histiocytosis" (ND-LCH) is a rare and severe complication of LCH presenting as a progressive cerebellar ataxia associated with pyramidal tract signs, and cognitive impairment. MRI is the gold standard to investigate CNS lesions of ND-LCH but little is known ...

journal_title：Journal of neurology

authors： Ribeiro MJ,Idbaih A,Thomas C,Remy P,Martin-Duverneuil N,Samson Y,Donadieu J,Hoang-Xuan K

更新日期：2008-04-01 00:00:00

abstract：:Patients in a minimally conscious state (MCS) show restricted signs of awareness but are unable to communicate. We assessed cerebral glucose metabolism in MCS patients and tested the hypothesis that this entity can be subcategorized into MCS- (i.e., patients only showing nonreflex behavior such as visual pursuit, loca...

journal_title：Journal of neurology

authors： Bruno MA,Majerus S,Boly M,Vanhaudenhuyse A,Schnakers C,Gosseries O,Boveroux P,Kirsch M,Demertzi A,Bernard C,Hustinx R,Moonen G,Laureys S

更新日期：2012-06-01 00:00:00

abstract：:Alien limb syndrome following stroke within the territory of the posterior cerebral artery is exceedingly rare. A right-handed female experienced left homonymous hemianopia, visuospatial neglect, and proprioceptive loss of her left hemi-body. She experienced unintended, involuntary movements of her left arm and hand, ...

journal_title：Journal of neurology

authors： Nowak DA,Engel A,Leutbecher M,Zeller C

更新日期：2020-01-01 00:00:00

abstract：:Fatigue is a frequent and often severe symptom in multiple sclerosis. Pathogenic mechanisms proposed for fatigue include the release of proinflammatory cytokines, which is thought to have an important effect on changes in the blood-brain barrier (BBB). To investigate whether fatigue is related to BBB disruption we stu...

journal_title：Journal of neurology

authors： Mainero C,Faroni J,Gasperini C,Filippi M,Giugni E,Ciccarelli O,Rovaris M,Bastianello S,Comi G,Pozzilli C

更新日期：1999-06-01 00:00:00

abstract：:Lipids were extracted from brains of a patient with membranous lipodystrophy (ML) and three normal patients and the neutral lipid and sphingolipid constituents were investigated. The storage of a large amount of free fatty acid was observed in the ML brain, but no cholesterol ester was found. Total lipid, cholesterol ...

journal_title：Journal of neurology

authors： Ohtani Y,Miura S,Tamai Y,Kojima H,Kashima H

更新日期：1979-03-22 00:00:00

abstract：:A boy was suspected of having meningoencephalitis probably of viral origin, although all microbiological, including virological, tests were negative. Postmortem examination revealed a dissecting aortic aneurysm and disseminated intravascular coagulation involving the central nervous system exclusively. The clinical ev...

journal_title：Journal of neurology

authors： Hens L,Dom R,Goddeeris P,van den Bergh R

更新日期：1981-01-01 00:00:00

abstract：:We measured changes in brain magnetization transfer ratio (MTR) as a potential indicator of myelin density in brain tissue of patients with relapsing-remitting multiple sclerosis (RRMS) treated with delayed-release dimethyl fumarate (DMF) in the Phase 3 DEFINE study. DEFINE was a randomized, double-blind, placebo-cont...

journal_title：Journal of neurology

authors： Arnold DL,Gold R,Kappos L,Bar-Or A,Giovannoni G,Selmaj K,Yang M,Zhang R,Stephan M,Sheikh SI,Dawson KT

更新日期：2014-12-01 00:00:00

abstract：:Interferon beta (IFNbeta) therapy for multiple sclerosis (MS) is associated with a potential for the development of neutralising antibodies (NAbs) that negatively affect therapy. Several factors influence the development of NAbs, such as lack of complete sequence homology with the endogenous IFNbeta sequence, frequenc...

journal_title：Journal of neurology

authors： Hartung HP,Polman C,Bertolotto A,Deisenhammer F,Giovannoni G,Havrdova E,Hemmer B,Hillert J,Kappos L,Kieseier B,Killestein J,Malcus C,Comabella M,Pachner A,Schellekens H,Sellebjerg F,Selmaj K,Sorensen PS

更新日期：2007-07-01 00:00:00

abstract：:Although the beneficial effect of subcutaneous injections of botulinum toxin type A (BTX-A) is well known in both blepharospasm and hemifacial spasm, the position of the injection sites around the orbicularis oculi may influence the effectiveness and side effects. Here we report results of preseptal and pretarsal BTX-...

journal_title：Journal of neurology

authors： Cakmur R,Ozturk V,Uzunel F,Donmez B,Idiman F

更新日期：2002-01-01 00:00:00

abstract：:In this review, we describe the wide clinical spectrum of features that can be seen in multiple system atrophy (MSA) with a focus on the premotor phase and the non-motor symptoms providing an up-to-date overview of the current understanding in this fast-growing field. First, we highlight the non-motor features at dise...

journal_title：Journal of neurology

authors： Chelban V,Catereniuc D,Aftene D,Gasnas A,Vichayanrat E,Iodice V,Groppa S,Houlden H

更新日期：2020-09-01 00:00:00

abstract：:Myasthenia gravis (MG) is the archetypic disorder of both the neuromuscular junction and autoantibody-mediated disease. In most patients, IgG1-dominant antibodies to acetylcholine receptors cause fatigable weakness of skeletal muscles. In the rest, a variable proportion possesses antibodies to muscle-specific tyrosine...

journal_title：Journal of neurology

authors： Binks S,Vincent A,Palace J

更新日期：2016-04-01 00:00:00

abstract：:Two patients with chorea and polycythaemia vera are described. The literature on this rare association is reviewed and its pathophysiology discussed. ...

journal_title：Journal of neurology

authors： Mas JL,Gueguen B,Bouche P,Derouesné C,Varet B,Castaigne P

更新日期：1985-01-01 00:00:00

abstract：:Spinocerebellar ataxia (SCA) type 7 is an autosomal dominant disorder characterized by neural loss, mainly in the cerebellum and regions of the brainstem and particularly the inferior olivary complex. This neurodegeneration disease is associated with expansion of unstable CAG repeats within the 5'-translated region of...

journal_title：Journal of neurology

authors： Hsieh M,Lin SJ,Chen JF,Lin HM,Hsiao KM,Li SY,Li C,Tsai CJ

更新日期：2000-08-01 00:00:00

abstract：:A 23-year-old woman had progressive right hemiparesis followed by spontaneous clinical remission. The clinical profile and multifocal contrast-enhancing CT lesions in the periventricular region of the cerebrum favored the diagnosis of an acute demyelinating process. Serial examinations showed resolution of CT abnormal...

journal_title：Journal of neurology

authors： Kuroiwa Y,Nishimura Y,Kobayashi S,Mizoguchi K,Honda N

更新日期：1982-01-01 00:00:00

abstract：:Genetic evidence indicates a central role of cerebral accumulation of beta-amyloid (Abeta) in the pathogenesis of Alzheimer's disease (AD). Beside presenilin 1 and 2, three other recently discovered proteins (Aph 1, PEN 2 and nicastrin) are associated with gamma-secretase activity, the enzymatic complex generating Abe...

journal_title：Journal of neurology

authors： Sala Frigerio C,Piscopo P,Calabrese E,Crestini A,Malvezzi Campeggi L,Civita di Fava R,Fogliarino S,Albani D,Marcon G,Cherchi R,Piras R,Forloni G,Confaloni A

更新日期：2005-09-01 00:00:00

abstract：:The history of our understanding of the pathogenesis and pathophysiology of multiple sclerosis are reviewed in the context of Charcot's contribution. The implications for treatment of the new knowledge gained from studies during life of pathology and pathogenesis (by MRI) and pathophysiology (by evoked potentials) are...

journal_title：Journal of neurology

authors： McDonald WI

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To explore the value of olfactory identification deficits as a predictor of cerebral β-amyloid status and other markers of brain health in cognitively normal adults aged ~ 70 years. METHODS:Cross-sectional observational cohort study. 389 largely healthy and cognitively normal older adults were recruited from...

journal_title：Journal of neurology

authors： Buchanan SM,Parker TD,Lane CA,Keshavan A,Keuss SE,Lu K,James SN,Murray-Smith H,Wong A,Nicholas J,Cash DM,Malone IB,Coath W,Thomas DL,Sudre C,Fox NC,Richards M,Schott JM

更新日期：2020-11-01 00:00:00

abstract：:Rapid Eye Movement sleep behavior disorder (RBD) is a parasomnia causing sufferers to physically act out their dreams. These behaviors can disrupt sleep and sometimes lead to injuries in patients and their bed-partners. Clonazepam and melatonin are the first-line pharmacological treatment options for RBD based on dire...

journal_title：Journal of neurology

authors： Gilat M,Marshall NS,Testelmans D,Buyse B,Lewis SJG

更新日期：2021-01-07 00:00:00