Abstract:
BACKGROUND:Elective programs for medical students in the last year of their university training are poorly evaluated. The goal of this study was to determine the gain in theoretical and practical skills in a group of students during their elective in neurology. Students were trained by either conventional teaching methods or applying improved problem-based teaching. METHOD:A test of 78 multiple choice questions regarding both, theoretical and practical aspects of clinical neurology, was presented to 21 students (9 female, 12 male). This group of students (group A) was trained according to the conventional teaching method. A subsequent group of students (intervention group B; n = 19; 9 female; 10 male) was educated using a modified teaching method that consisted of more problem-based learning, gathering experience with neurosonological and neurophysiological principles and in intense bedside teaching. The test was performed at the beginning and end of their elective period. The percentage increase in the tests was taken as the primary endpoint. In addition, all students were asked about their degree of satisfaction with the elective in general. RESULTS:Students of both groups did not differ with regard to age, gender, number of semesters, score of last examination and score of the test at the beginning of the elective. However, students who participated in the problem-based teaching group (group B) performed significantly better in the test at the end of the elective (increase 16.3% +/- 15.5) than those who were trained according to the conventional teaching program (percentage increase 6.3% +/- 9.4; p = 0.017). Students of both groups were highly satisfied with the elective in general. CONCLUSION:More problem-based teaching including practical exercises and intense bed-side teaching significantly improved students' performance. Thus, adaptation of teaching covering these aspects should be encouraged and might improve the neurological knowledge and skills of the students.
journal_name
J Neuroljournal_title
Journal of neurologyauthors
Heckmann JG,Bleh C,Dütsch M,Lang CJ,Neundörfer Bdoi
10.1007/s00415-003-0255-5keywords:
subject
Has Abstractpub_date
2003-12-01 00:00:00pages
1464-8issue
12eissn
0340-5354issn
1432-1459journal_volume
250pub_type
杂志文章abstract::The finding of a mutation in the alpha-synuclein gene in a rare autosomal dominant form of idiopathic Parkinson's disease (IPD), has prompted increased interest in identifying genes that account for the more common sporadic form. A number of association studies have suggested that functional polymorphisms in genes tha...
journal_title:Journal of neurology
pub_type: 杂志文章,评审
doi:10.1007/s004150050258
更新日期:1998-10-01 00:00:00
abstract::Whole genome screening is increasingly used to identify genetic risk factors for complex diseases. In this study, a genome wide linkage disequilibrium (LD) screen was performed in a cohort of Parkinson's disease (PD) patients from the UK (n = 195) using pooled DNA to facilitate efficient genotyping of 5546 microsatell...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-005-0686-2
更新日期:2005-05-01 00:00:00
abstract::Functional magnetic resonance imaging (fMRI) of hand movements in amyotrophic lateral sclerosis (ALS) has repeatedly demonstrated increased activation in cortical and subcortical areas, whereas a single study has suggested decreased rather than increased activations for tongue movements in patients with bulbar involve...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-010-5842-7
更新日期:2011-05-01 00:00:00
abstract::In vivo nuclear magnetic resonance spectroscopy (MRS) of the human brain is a recently developed technique which allows to assay noninvasively in vivo key molecules of brain metabolism. After a review of the origin of the signals detected by phosphorus and proton MRS of human brain, the impact of MRS on clinical neuro...
journal_title:Journal of neurology
pub_type: 社论,评审
doi:10.1007/BF02033352
更新日期:1994-05-01 00:00:00
abstract::Mutations in C19orf12 have been recently identified as the molecular genetic cause of a subtype of neurodegeneration with brain iron accumulation (NBIA). Given the mitochondrial localization of the gene product the new NBIA subtype was designated mitochondrial membrane protein-associated neurodegeneration. Frequent fe...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-012-6521-7
更新日期:2012-11-01 00:00:00
abstract::A man, aged 46, who had been taking Clioquinol in high doses for a long period, developed a characteristic neurological syndrome of subacute myelo-optic neuropathy rather abruptly. Electron microscopical examination of the muscle biopsy, obtained five months after the onset of the disease, revealed severe degenerative...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:
更新日期:1977-05-13 00:00:00
abstract:BACKGROUND:Myelin oligodendrocyte glycoprotein immunoglobulin G associated optic neuritis (MOG-ON) is a recently described entity. Recent studies have shown that MOG-ON has a more severe clinical presentation than classic optic neuritis (ON). OBJECTIVE:This study aimed to define morphological characteristics of MOG-ON...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-020-10097-x
更新日期:2021-01-01 00:00:00
abstract::A woman affected by chronic progressive external ophthalmoplegia and muscle mitochondrial DNA deletion was studied by phosphorus magnetic resonance spectroscopy (31P-MRS) prior to and after 1 and 7 months of treatment with oral lipoic acid. Before treatment a decreased phosphocreatine (PCr) content was found in the oc...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00873552
更新日期:1995-07-01 00:00:00
abstract::In the epidemiological area of Southern Lower Saxony 92 patients with clinically definite or probable diagnosis of multiple sclerosis (MS) were interviewed and examined. This group contained a remarkably high percentage of benign cases (52%) in comparison with a sample of hospitalized patients. Neurological examinatio...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313292
更新日期:1981-01-01 00:00:00
abstract::Two patients with chorea and polycythaemia vera are described. The literature on this rare association is reviewed and its pathophysiology discussed. ...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313895
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Dysphagia is estimated to occur in up to 50% of the stroke neurorehabilitation population. Those patients with severe neurogenic oropharyngeal dysphagia (NOD) may receive feeding gastrostomy tubes (FGT) if noninvasive therapies prove ineffective in eliminating aspiration or sustaining adequate nu...
journal_title:Journal of neurology
pub_type: 临床试验,杂志文章
doi:10.1007/s00415-005-0906-9
更新日期:2005-12-01 00:00:00
abstract::Parkinson's disease (PD) is preceded by a premotor phase of unknown duration. Dopaminergic degeneration during this phase may lead to subtle cognitive and behavioural changes, such as decreased novelty seeking. Consequently, premotor subjects might be most comfortable in jobs that do not require optimal dopamine level...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-015-7828-y
更新日期:2015-09-01 00:00:00
abstract::The aim of our study was to compare the results obtained by intraoperative and postoperative subthalamic nucleus (STN) macrostimulation in Parkinson's disease (PD). One hundred three PD patients implanted with bilateral STN stimulation were included. The thresholds for efficacy and side effects (motor contraction; par...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-010-5543-2
更新日期:2010-09-01 00:00:00
abstract::The aim of the study was to identify the main factors that impact mobility impairment in multiple sclerosis (MS) patients in Italy. Clinicians from a large number of Italian MS centers took part in a Delphi process aimed at obtaining consensus statements among the participants. Large consensus was obtained for stateme...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-013-7230-6
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:The increase in disease-modifying drugs (DMDs) allows individualization of treatment in relapsing multiple sclerosis (RMS); however, the long-term impact of different treatment sequences is not well established. This is particularly relevant for MS patients who may need to postpone more aggressive DMD strate...
journal_title:Journal of neurology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00415-019-09531-6
更新日期:2019-12-01 00:00:00
abstract:: ...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-019-09192-5
更新日期:2019-03-01 00:00:00
abstract::Although central facial paresis (CFP) is a major symptom of stroke, there is a lack of studies on the motor and non-motor disabilities in stroke patients. A prospective cohort study was performed at admission for inpatient rehabilitation and discharge of post-stroke phase of 112 patients (44% female, median age: 64 ye...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-018-9099-x
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND AND AIMS:The association between multiple sclerosis (MS) and depression has been well established but prevalence estimates have varied widely. The aims of this study were to assess the point prevalence of previously unrecognised symptoms of depression in a community-based population with MS and examine their...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-005-0963-0
更新日期:2006-02-01 00:00:00
abstract::Two previously healthy women are described who in their late thirties suffered transient strokelike episodes, consisting of initial headache and vomiting, with various subsequent neurological signs that were only partially reversible. Investigations revealed elevated serum creatine kinase, lactic acidosis, hypertrigly...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00818708
更新日期:1993-01-01 00:00:00
abstract::To further evaluate (1) transcranial sonography (TCS) for (pre)clinical diagnosis of Parkinson's disease (PD) and (2) to examine asymptomatic carriers of Parkin mutations we investigated substantia nigra (SN) hyperechogenicity in PD patients and unaffected subjects with and without Parkin mutations. The area (aSN) of ...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-007-0567-y
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Parkinson's disease (PD) reduces independence and quality of life through deterioration of upper limb motor function. Transcranial direct current stimulation (tDCS) may offer an alternative, adjunctive therapy for PD. However, the efficacy of tDCS for upper limb motor rehabilitation in PD is unkn...
journal_title:Journal of neurology
pub_type: 杂志文章,评审
doi:10.1007/s00415-019-09385-y
更新日期:2020-12-01 00:00:00
abstract::We describe three patients with unilateral asterixis. One diabetic patient with a moderately-sized haematoma in the left putamen initially developed bilateral and symmetrical asterixis, which became confined to the right side as his diabetes mellitus was controlled. Two patients showed unilateral asterixis due to haem...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314766
更新日期:1990-12-01 00:00:00
abstract:INTRODUCTION:Intracranial lipomas are rare, mostly congenital lesions. Sporadic case reports suggest an association with focal epilepsy. METHODS:All admissions to our epilepsy monitoring unit who had had brain MRI were reviewed for intracranial lipomas during 6 consecutive years. RESULTS:Five patients with intracrani...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-006-0065-7
更新日期:2006-05-01 00:00:00
abstract::The clinicopathological findings of a 50-year-old man, who developed cervicothoracic syringomyelia at the age of 25 are presented. He was given radiation therapy at the age of 33. At the age of 57 he developed a foramen jugulare syndrome on the left, caused by a low grade leiomyosarcoma. Etiologically, the most attrac...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313150
更新日期:1980-01-01 00:00:00
abstract::Somatostatin levels were measured in cerebrospinal fluid of patients with Alzheimer's disease, multi-infarct dementia and normal pressure hydrocephalus and compared with levels from a normal control group. All pathological groups showed a statistically significant decrease of somatostatin with respect to the control g...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00319684
更新日期:1991-06-01 00:00:00
abstract::The influence of portal-systemic shunting on maximal motor nerve conduction velocity (MCV) was analyzed in rats with portacaval shunts. At 3 and 8 weeks after the shunting there was a marked but transient fall in MCV. This was not prevented by colectomy. At 16 weeks the MCV had almost normalized, despite sustained por...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313181
更新日期:1980-01-01 00:00:00
abstract::Three patients with postural and intention cerebellar tremor caused by a cerebellar infarction in the superior cerebellar artery distribution were studied; treatment with carbamazepine resulted in marked improvement. ...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00328507
更新日期:1989-12-01 00:00:00
abstract::To investigate the role of endogenous opioid peptides in the pathophysiology of cerebral ischaemia, the CSF levels of immunoreactive beta-endorphin and leu-enkephalin in 16 patients with cerebral infarction were measured. Both the CSF beta-endorphin and leu-enkephalin levels in the acute stage of cerebral infarction w...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314282
更新日期:1987-06-01 00:00:00
abstract::Quality of Life (QoL) is the preferred outcome in non-pharmacological trials, but there is little UK population evidence of QoL in epilepsy. In advance of evaluating an epilepsy self-management course we aimed to describe, among UK participants, what clinical and psycho-social characteristics are associated with QoL. ...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-017-8512-1
更新日期:2017-06-01 00:00:00
abstract::Disability in multiple sclerosis (MS) patients is associated with white matter (WM) and gray matter (GM) pathology, and both processes contribute differently over the disease course. Total and regional GM volume loss can be imaged via voxel-based morphometry (VBM). Here, we retrospectively analyzed a group of 213 MS p...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-016-8114-3
更新日期:2016-06-01 00:00:00