Intracranial lipomas and epilepsy.

Abstract:

INTRODUCTION:Intracranial lipomas are rare, mostly congenital lesions. Sporadic case reports suggest an association with focal epilepsy. METHODS:All admissions to our epilepsy monitoring unit who had had brain MRI were reviewed for intracranial lipomas during 6 consecutive years. RESULTS:Five patients with intracranial lipomas were identified (0.14%). Lipomas were located in the midline (3 cases), in the tectal region, and over the parietal cortex. Another intracranial pathology was identified in two patients causing the epilepsy in these cases (head trauma and hemimegaencephaly). In two other cases the Video EEG monitoring findings were not congruent with the location of the lipoma, but no other explanation for their epilepsy was found. In one patient a large midline lipoma extending into the right lateral ventricle was thought to be the cause of the patient's right hemispheric seizures. No other clinical symptoms or complications of the lipomas were noted. DISCUSSION:Intracranial lipomas are rare, incidental, often asymptomatic findings and usually located near the midline. In only one of our five patients was the lipoma interpreted as the definite cause of the epilepsy.

journal_name

J Neurol

journal_title

Journal of neurology

authors

Loddenkemper T,Morris HH 3rd,Diehl B,Lachhwani DK

doi

10.1007/s00415-006-0065-7

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

590-3

issue

5

eissn

0340-5354

issn

1432-1459

journal_volume

253

pub_type

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