Factors affecting warfarin dose requirements and quality of anticoagulation in adult Egyptian patients: role of gene polymorphism.

abstract：INTRODUCTION:Medullary carcinoma of the thyroid (MTC) is a rare tumour which occurs in both sporadic and hereditary forms. Mutations of the RET proto-oncogene have been identified in hereditary forms. The aim of our study was to confirm or exclude familial disease by examining for germline mutations in the RET proto-on...

journal_title：Irish journal of medical science

authors： O'Keeffe DA,Hill AD,Sheahan K,Ryan F,Barton D,Fitzgerald RJ,McDermott EW,O'Higgins NJ

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Most femoral neck fractures in younger patients have a different mechanism, treatment, and prognosis from those in elderly patients. AIMS:To evaluate the results of internal fixation of femoral neck fractures in patients aged between 20 and 60 years, and to determine reasons for failure. PATIENTS AND METHO...

journal_title：Irish journal of medical science

authors： Farooq MA,Orkazai SH,Okusanya O,Devitt AT

更新日期：2005-10-01 00:00:00

abstract：:Over a four year period, 20 segments in 16 patients were treated by lengthening by callotasis or chondrodiastasis. The indications for treatment were leg length discrepancy in 13 patients and short stature in three. Patients with leg length discrepancy were all treated by femoral lengthening; the mean length gained wa...

journal_title：Irish journal of medical science

authors： O'Beirne J,Maher M,O'Flanagan S,McGuinness A

更新日期：1993-08-01 00:00:00

abstract：:The evaluation of fetal health using ultrasound to establish a biophysical profile in the Rotunda Hospital in 1987 is reported. The corrected perinatal mortality rate fell from 10.0 in 1986 to 6.9 per 1,000 for babies over 500g and from 5.9 in 1986 to 3.4 for babies over 1,000g. This was achieved without significant a...

journal_title：Irish journal of medical science

authors： Gaughan B

更新日期：1989-07-01 00:00:00

abstract：INTRODUCTION:We conducted a study at two main centres for paediatric surgery in the Republic of Ireland, Temple Street Children's University Hospital (TSCUH) and Our Lady's Children's Hospital Crumlin (OLCHC). AIM:The aim of the study was to assess doctors' opinions, frequency and methods of smartphone use in clinical...

journal_title：Irish journal of medical science

authors： El Hadidy TS,Alshafei AE,Mortell AE,Doherty EM

更新日期：2018-08-01 00:00:00

abstract：:In a prospective study designed to assess the effect of duration of antibiotic therapy on the helicobactericidal and ulcer healing efficacy of bismuth therapy, groups of patients, 10 in each group, with H. pylori-positive duodenal ulcer received a triple therapy regimen consisting of colloidal bismuth subcitrate 120 m...

journal_title：Irish journal of medical science

authors： O'Connor HJ,Cunnane K,Collins JS,Sloan JM,Johnston BT,Bamford KC,Gilvarry J,O'Morain CA

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Nearly half of the Irish population is covered by private health insurance. In recent years, premium inflation has been significantly ahead of overall inflation and has been accelerating. This has contributing to a drop in the numbers insured since the peak in 2008. The fall in the numbers with private healt...

journal_title：Irish journal of medical science

authors： Turner B

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Posterior reversible encephalopathy syndrome (PRES) is associated with variable predisposing risk factors including preeclampsia and eclampsia since it proposed. However, studies of large case series focusing on pregnancy-related PRES are still limited. We performed a large retrospective study of patients wi...

journal_title：Irish journal of medical science

authors： Wen Y,Yang B,Huang Q,Liu Y

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Chronic anal fissures (CAF) are caused by anal sphincter hypertonia leading to an ischaemic ulcer. By inducing temporary sphincter relaxation, botulinum toxin (Botox) injection has been shown to heal CAF in approximately 73-96% of cases in clinical trials. AIM:This study looks at the efficacy of Botox clini...

journal_title：Irish journal of medical science

authors： Simms HN,McCallion K,Wallace W,Campbell WJ,Calvert H,Moorehead RJ

更新日期：2004-10-01 00:00:00

abstract：INTRODUCTION:Biclonal lymphoid disorders, when two distinct lymphoproliferative disorders (LPD) co-exist, are rare (incidence of 1.4%) and associated with a poor prognosis. NOTCH1 mutations occur in 10% of CLL at diagnosis, associated with a short disease-free interval and increased risk of Richter's transformation. We...

journal_title：Irish journal of medical science

authors： Fogarty H,Dowling A,O'Brien D,Langabeer S,Bacon CL,Flavin R,O'Dwyer M,Hennessy B,O'Leary H,Crotty G,Henderson R,Nolan J,Thornton P,Vandenberghe E,Quinn F

更新日期：2020-10-17 00:00:00

abstract：BACKGROUND:Cadmium (Cd) is an environmental and industrial pollutant that induces a broad spectrum of toxicological effects, influences a variety of human organs, and is associated with poor semen quality and male infertility. Increasing evidence demonstrates that Cd induces testicular germ cell apoptosis in rodent ani...

journal_title：Irish journal of medical science

authors： Ou Z,Chen Y,Niu X,He W,Song B,Fan D,Sun X

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Attitudes have been shown to be important determinants of the quality and efficacy of medical care. There is little research on the education about, and assessment of, attitudes in undergraduate medical education. AIM:To describe the design and delivery of an attitude awareness workshop, and the associated ...

journal_title：Irish journal of medical science

authors： Kelly ME,Fenlon NP,Murphy AW

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Since their original description in 1687, aneurysms of the extracranial internal carotid artery (ICA) remain rare and account for less than 2% of all carotid operations (Zwolak et al. in: J Vasc Surg 1:415-422, 1984; El-Sabrout, Cooley in: J Vasc Surg 31:702-712, 2000). Cerebrovascular morbidity and mortalit...

journal_title：Irish journal of medical science

authors： Noad RL,O'Donnell ME,McCavert M,Gardner R,Lee B,Lau LL

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The management of patients with chronic pain is challenging. The aim of treatment is alleviation of symptoms in an attempt to increase functional capacity. Interventional procedures, such as chemical neurolysis are adopted when other techniques fail to provide adequate pain control. RESULTS:An 82-year-old m...

journal_title：Irish journal of medical science

authors： Al-Hilli Z,Deasy J,Keaveny J

更新日期：2010-09-01 00:00:00

abstract：:The management of patients with suspected post laparotomy intra-abdominal sepsis poses a major therapeutic challenge to clinicians. The mortality is high and the optimal interventional modality remains ill-defined. We define the incidence, diagnostic methodology, pre- and postoperative findings and outcome of patients...

journal_title：Irish journal of medical science

authors： McCrory C,Crowley K

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:There is little known regarding how familiar parents are with the newborn bloodspot screening (NBS) test or how well parents of a child with a screen-detected condition understand that condition initially. AIM:The study aim was to examine parental NBS awareness and conditions screened. METHODS:Two studies ...

journal_title：Irish journal of medical science

authors： Fitzpatrick P,Fitzgerald C,Somerville R,Linnane B

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a progressive illness that is mostly managed in the general practice setting. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines are the international gold standard, and it is important to understand how these are being applied in gene...

journal_title：Irish journal of medical science

authors： Sehl J,O'Doherty J,O'Connor R,O'Sullivan B,O'Regan A

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:Prostate cancer is the most common solid cancer affecting men in Ireland. Transrectal ultrasound (TRUS) biopsies of the prostate are routinely performed to diagnose prostate cancer. They are, in general, a safe procedure but are associated with a significant risk of infective complications ranging from fev...

journal_title：Irish journal of medical science

authors： Smyth LG,Mulvin DW

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Dysphagia affects up to 30% of hospitalized patients, and it is associated with numerous complications. AIMS:Assess the impact of a 24/7 dysphagia screening protocol in an Internal Medicine Unit regarding respiratory complications (such as aspiration pneumonia) as the primary outcome. Length of stay and dis...

journal_title：Irish journal of medical science

authors： Taveira I,Silva S,Bonança Í,Parreira D,Antunes C

更新日期：2020-09-22 00:00:00

abstract：:Two-hundred and eleven Irish GPs responded to a questionnaire survey of their experience and management of acute myocardial infarction (MI) and their attitudes to the use of thrombolytic therapy Three-quarters of the respondents felt they dealt with three or more MIs per year; most felt that the majority of MIs were i...

journal_title：Irish journal of medical science

authors： Murphy AW,Power R,Ungruh K,Bury G

更新日期：1992-10-01 00:00:00

abstract：INTRODUCTION:Otitis externa (OE) is an extremely common dermatological condition that can affect social life and employment, but formal studies of its general health impact are lacking. OBJECTIVE:The aims of this study were two-folded, first to assess the impact of OE on various health determinants as measured by the ...

journal_title：Irish journal of medical science

authors： Ali R,Burns P,Donnelly M

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:In 1996, Irish accident and emergency (A&E) departments had approximately 1.2 million visits. General practitioners (GPs) have been shown to work efficiently in A&E. AIM:This study aimed to describe the current A&E structures in Ireland and the potential contribution of general practice. METHOD:Questionnai...

journal_title：Irish journal of medical science

authors： Bury G,Hungerford P,Langton D,Plunkett P

更新日期：2000-10-01 00:00:00

abstract：INTRODUCTION:Heparin-induced thrombocytopenia syndrome (HITS) is an infrequent complication of heparin anticoagulation. CASE REPORT:We present the case of a 44-year-old male who was admitted with acute ischaemia of his right lower limb. He was initially treated with unfractionated heparin and thrombolysis, but subsequ...

journal_title：Irish journal of medical science

authors： Collins D,Moloney MA,O'Donnell D,Brophy D,Sheehan SJ

更新日期：2012-09-01 00:00:00

abstract：:The use of injectable gold in the treatment of rheumatoid arthritis (RA) is hampered by the high incidence of adverse reactions of which myelotoxicity is potentially the most serious. Regular full blood count (FBC) monitoring prior to each injection, a practice which requires much time and effort, has never been fully...

journal_title：Irish journal of medical science

authors： Cervi PL,Wright P,Casey EB

更新日期：1992-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to analyze neuropathic pain (NeP) and its therapy in patients with Guillain-Barré syndrome (GBS) during a 6-month follow-up period. METHOD:This longitudinal multicenter study included 69 newly diagnosed adult GBS patients. NeP diagnosis was based on the criteria of Finnerup and conf...

journal_title：Irish journal of medical science

authors： Vukojevic Z,Berisavac I,Bozovic I,Dominovic-Kovacevic A,Lavrnic D,Peric S

更新日期：2020-10-15 00:00:00

abstract：AIMS:Many studies have suggested Cytomegalovirus infection might be implicated in steroid-refractory inflammatory bowel disease (IBD), in which situation management is extremely difficult. CMV infection being a potential cause of IBD have drawn great attention of clinicians, with insufficient evidence to reach conclusi...

journal_title：Irish journal of medical science

authors： Liu CC,Ji S,Ding Y,Zhou L,Liu X,Li W

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:We describe a case of Cushing's syndrome due to ectopic ACTH secretion, where the only potential source on conventional imaging was a tiny benign-appearing lung nodule, which failed to take up radiolabelled octreotide. DESIGN AND METHODS:To determine whether the patient might respond to therapeutic administr...

journal_title：Irish journal of medical science

authors： McDermott JH,Thabit H,Hickey N,Thompson C,Gaffney E,Young V,Sreenan S

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Evaluate condylar, ramal, and condylar plus ramal vertical mandibular asymmetry in patients with unilateral posterior crossbite (UPCB) and in patients with unilateral cleft lip and palate (UCLP) compared with subjects having normal occlusion. DESIGN:This cross-sectional study evaluated panoramic radiographs ...

journal_title：Irish journal of medical science

authors： Abad-Santamaría L,López-de-Andrés A,Jiménez-Trujillo I,Ruíz C,Romero M

更新日期：2014-09-01 00:00:00

abstract：INTRODUCTION:Extrahepatic Portal Hypertension (EPH) is defined as extrahepatic hypertension of the portal venous system in the absence of liver cirrhosis. Isolated splenic vein stenosis/occlusion as one of the causes of extrahepatic portal hypertension is uncommon, comprising less than 5 % of all cases of portal hypert...

journal_title：Irish journal of medical science

authors： El Kininy W,Kearney L,Hosam N,Broe P,Keeling A

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:Although good evidence exists regarding the clinical effectiveness of mechanical thrombectomy for people with acute ischaemic stroke, cost-effectiveness should also be considered. The aim of this study was to systematically review the evidence of cost-effectiveness of emergency endovascular therapy using mechan...

journal_title：Irish journal of medical science

authors： Teljeur C,Harrington P,Glynn RW,Ryan M

更新日期：2019-08-01 00:00:00