Enhanced hyperplasia of gastric enterochromaffinlike cells in response to omeprazole-evoked hypergastrinemia in rats with portacaval shunts. An immunocytochemical and chemical study.

abstract：:We studied 375 chronic hemodialysis patients for evidence of hepatitis B virus infection using first- and second-generation monoclonal radioimmunoassays. These assays employ high-affinity monoclonal antibodies produced against antigenic determinants that reside on hepatitis B surface antigen. Such assays have a lower ...

journal_title：Gastroenterology

authors： Fujita YK,Kamata K,Kameda H,Isselbacher KJ,Wands JR

更新日期：1986-12-01 00:00:00

abstract：:The aim of this study was to assess the effect of cell culture on the bradykinin receptor of rabbit colon myocytes. In longitudinal muscle strips prepared from distal colon, bradykinin stimulated dose-dependent contraction that was 62% of the maximal response to bethanecol. At 4 degrees C, [3H]bradykinin binding to fr...

journal_title：Gastroenterology

authors： Hyman PE,Diego A,Ridout D,Yuan QX,Ennes H,Cominelli F,Snape WJ Jr,Tomomasa T

更新日期：1992-05-01 00:00:00

abstract：:The growth rate of 31 asymptomatic hepatocellular carcinomas (diameter less than or equal to 5 cm) discovered in 28 patients by a prospective screening program was determined by real-time ultrasonography over 36-860 days. Except for one tumor that shrank on follow-up, the doubling time ranged from 29 to 398 days, with...

journal_title：Gastroenterology

authors： Sheu JC,Sung JL,Chen DS,Yang PM,Lai MY,Lee CS,Hsu HC,Chuang CN,Yang PC,Wang TH

更新日期：1985-08-01 00:00:00

abstract：:In this review, we speculate about future therapeutic approaches for inflammatory bowel diseases (IBDs), focusing on the need for better preclinical and clinical models and approaches beyond small molecules and systemically administered biologics. We offer ideas to change clinical trial programs and to use immunologic...

journal_title：Gastroenterology

authors： Plevy SE,Targan SR

更新日期：2011-05-01 00:00:00

abstract：:We are delighted to introduce a new and simple format in the references section of the articles we publish in Gastroenterology that highlights joint first authors of citations. We believe this is an important step to acknowledging equal contribution to published work as research becomes increasingly team-oriented and ...

journal_title：Gastroenterology

authors： Dubnansky E,Omary MB

更新日期：2012-10-01 00:00:00

abstract：:To identify prognostic factors in cirrhotic patients admitted to the hospital for the treatment of an episode of ascites, a survival analysis was performed in a series of 139 patients hospitalized in our Unit between 1980 and 1985. Mean follow-up was 12.8 +/- 14.2 mo (mean +/- SD). A total of 38 variables based on his...

journal_title：Gastroenterology

authors： Llach J,Ginès P,Arroyo V,Rimola A,Titó L,Badalamenti S,Jiménez W,Gaya J,Rivera F,Rodés J

更新日期：1988-02-01 00:00:00

abstract：:The hepatic circulation is reviewed with emphasis on the role of hepatic blood vessels in hepatic and homeostatic functions. Contrasts are made with resistance, capacitance, and fluid exchange functions in other better known vascular beds. Hemodynamic changes that produce shifts in fluid exchange in other tissues are ...

journal_title：Gastroenterology

authors： Lautt WW

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND & AIMS:Feeding intolerance because of functional gastrointestinal dysmotility and parenteral nutrition-associated cholestasis (PNAC) are common problems in preterm, very-low-birth-weight (VLBW) infants. This double-blind, randomized, placebo-controlled study aimed to assess the effectiveness of "high-dose" o...

journal_title：Gastroenterology

authors： Ng PC,Lee CH,Wong SP,Lam HS,Liu FY,So KW,Lee CY,Fok TF

更新日期：2007-05-01 00:00:00

abstract：:Regional differences in the esophageal distribution and clearance of refluxed gastric acid was studied in seven asymptomatic volunteers and seven patients with reflux esophagitis. Intraluminal pH was recorded for 3 postprandial hours from the distal, middle, and proximal esophagus on two separate occasions (with subje...

journal_title：Gastroenterology

authors： Shaker R,Dodds WJ,Helm JF,Kern MK,Hogan WJ

更新日期：1991-08-01 00:00:00

abstract：:We have investigated the effect of oral cisapride (10 mg t.i.d.) in a double-blind, placebo-controlled trial in 26 patients with upper gut dysmotility: 11 with gastroparesis (8 diabetic, 3 idiopathic) and 15 with chronic idiopathic intestinal pseudoobstruction. Patients were evaluated at entry and at the end of the 6-...

journal_title：Gastroenterology

authors： Camilleri M,Malagelada JR,Abell TL,Brown ML,Hench V,Zinsmeister AR

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND & AIMS:Liver X receptors (LXRs) are transcriptional regulators of cholesterol metabolism, controlling cholesterol flow into cells, catabolism, and efflux. Cholesterol controls cell proliferation; disruptions in cholesterol metabolism have been associated with the development of colon cancer. We investigated ...

journal_title：Gastroenterology

authors： Lo Sasso G,Bovenga F,Murzilli S,Salvatore L,Di Tullio G,Martelli N,D'Orazio A,Rainaldi S,Vacca M,Mangia A,Palasciano G,Moschetta A

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND & AIMS:Practice guidelines recommend that endoscopists spend at least 7 minutes examining the colonic mucosa during colonoscopy withdrawal to optimize polyp yield. The aim of this study was to determine if the implementation of an institution-wide policy of colonoscopy withdrawal time > or = 7 minutes was as...

journal_title：Gastroenterology

authors： Sawhney MS,Cury MS,Neeman N,Ngo LH,Lewis JM,Chuttani R,Pleskow DK,Aronson MD

更新日期：2008-12-01 00:00:00

abstract：:By correlating morphological observations with quantitative measurements of net water transport, we determined whether bile salts altered colonic absorptive cells. Epithelial alteration was equivocal and water absorption was uninhibited during infusions of 1 mM deoxycholate or of concentrations of taurocholate less th...

journal_title：Gastroenterology

authors： Saunders DR,Hedges JR,Sillery J,Esther L,Matsumura K,Rubin CE

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND & AIMS:We have shown previously that cure of Helicobacter pylori infection leads to the disappearance of acid-neutralizing substances. Also, patients with ulcer after cure may gain weight. The aim of this study was to investigate whether cure of the infection increases the risk of reflux esophagitis. METHOD...

journal_title：Gastroenterology

authors： Labenz J,Blum AL,Bayerdörffer E,Meining A,Stolte M,Börsch G

更新日期：1997-05-01 00:00:00

abstract：:Sphincter of Oddi (SO) manometry was conducted in 48 subjects who had previously undergone cholecystectomy. Ten of these subjects had no detectable biliary or pancreatic disease and served as controls. The other 38 patients were presumed to have SO dysfunction and had presented with episodes of severe biliary-type pai...

journal_title：Gastroenterology

authors： Toouli J,Roberts-Thomson IC,Dent J,Lee J

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND & AIMS:It is not clear whether H2-receptor antagonists (H2RAs) reduce the risk of gastrointestinal (GI) bleeding in aspirin users at high risk. We performed a double-blind randomized trial to compare the effects of a proton pump inhibitor (PPI) vs a H2RA antagonist in preventing recurrent upper GI bleeding a...

journal_title：Gastroenterology

authors： Chan FK,Kyaw M,Tanigawa T,Higuchi K,Fujimoto K,Cheong PK,Lee V,Kinoshita Y,Naito Y,Watanabe T,Ching JY,Lam K,Lo A,Chan H,Lui R,Tang RS,Sakata Y,Tse YK,Takeuchi T,Handa O,Nebiki H,Wu JC,Abe T,Mishiro T,Ng S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND & AIMS:Postcolonoscopy colorectal cancer (PCCRC) is CRC diagnosed after a colonoscopy in which no cancer was found. A consensus article from the World Endoscopy Organization (WEO) proposed an approach for investigating and categorizing PCCRCs detected within 4 years of a colonoscopy. We aimed to identify cas...

journal_title：Gastroenterology

authors： Anderson R,Burr NE,Valori R

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND & AIMS:Accurate biomarkers of disease activity and therapeutic response can be valuable for clinical trials. We performed a post hoc analysis of data from a phase 2 trial to assess the relationship between the concentration of fecal calprotectin (FCP) and clinical and endoscopic outcomes of patients with mod...

journal_title：Gastroenterology

authors： Sandborn WJ,Panés J,Zhang H,Yu D,Niezychowski W,Su C

更新日期：2016-01-01 00:00:00

abstract：:Basal and pentagastrin-stimulated gastric acid secretion, fasting serum gastrin concentrations, and the gastric output of prostaglandin E and its major metabolite 13,14-dihydro 15-keto prostaglandin E2 were measured in 9 normal subjects before and after 14-20 days of dietary supplementation with linoleic acid. Mean ma...

journal_title：Gastroenterology

authors： Grant HW,Palmer KR,Kelly RW,Wilson NH,Misiewicz JJ

更新日期：1988-04-01 00:00:00

abstract：:Intramural pH of the gastric mucosa was measured using a microelectrode technique in rabbit gastric pouches under different secretory conditions and luminal acidity. Exposure of spontaneously secreting or metiamide-treated fundic pouches to a relatively high concentration of luminal acid. HCl 120 mM, for 60 min, led ...

journal_title：Gastroenterology

authors： Kivilaakso E,Fromm D,Silen W

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND & AIMS:We investigated the expression of estrogen receptor (ER) alpha and beta subtypes in cholangiocytes of normal and bile duct-ligated (BDL) rats and evaluated the role and mechanisms of estrogens in the modulation of cholangiocyte proliferation. METHODS:ER-alpha and ER-beta were analyzed by immunohistoc...

journal_title：Gastroenterology

authors： Alvaro D,Alpini G,Onori P,Perego L,Svegliata Baroni G,Franchitto A,Baiocchi L,Glaser SS,Le Sage G,Folli F,Gaudio E

更新日期：2000-12-01 00:00:00

abstract：:Disordered gustatory acuity was demonstrated in 22 patients with acute viral hepatitis and in 16 patients with chronic liver disease utilizing subjective responses and objective measurements of detection and recognition thresholds and scaling for NaCl, sucrose, HCl, and urea. In patients with early hepatitis and those...

journal_title：Gastroenterology

authors： Smith FR,Henkin RI,Dell RB

更新日期：1976-04-01 00:00:00

abstract：:The aim of this study was to correlate colonic motility with transit in 8 patients with functional diarrhea compared to 12 healthy subjects. Intraluminal pressure was measured with perfused catheter ports in the transverse colon, splenic flexure, and descending and sigmoid colons. Transit of the luminal contents was m...

journal_title：Gastroenterology

authors： Bazzocchi G,Ellis J,Villanueva-Meyer J,Reddy SN,Mena I,Snape WJ Jr

更新日期：1991-11-01 00:00:00

abstract：:The effects of bile salts on energy metabolism and acid secretion were investigated in the amphibian gastric mucosa in vitro. Serosal exposure to deoxycholate (0.2-2 mM), cholate (2-8 mM), or taurocholate (4-80 mM), at pH 7.4, decreased acid secretion depending on the concentration and time of exposure. Mucosal applic...

journal_title：Gastroenterology

authors： Núñez D,Chacín J

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND & AIMS:JC virus (JCV), a human polyomavirus, has been found in a limited number of normal human tissues and cancers. The oncogenic potential of this virus is mediated by a transforming protein, the T antigen (TAg). We have previously demonstrated the presence of JCV-TAg in colorectal cancers, in adjacent nor...

journal_title：Gastroenterology

authors： Ricciardiello L,Laghi L,Ramamirtham P,Chang CL,Chang DK,Randolph AE,Boland CR

更新日期：2000-11-01 00:00:00

abstract：:Interleukin 2, a soluble product of activated T lymphocytes, is of central importance in the development of an appropriate T-cell immune response. Defects in the production of or response to this lymphokine have been described in a variety of immune deficiency and autoimmune states, thus suggesting a role in the patho...

journal_title：Gastroenterology

authors： Fiocchi C,Hilfiker ML,Youngman KR,Doerder NC,Finke JH

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND & AIMS:Three-dimensional (3D) ultrasound imaging of the total stomach volume has not yet been achieved. The aim of this study was to investigate whether a magnetic position sensor system for acquisition of 3D ultrasonograms could be used to determine gastric emptying rates and intragastric distribution. MET...

journal_title：Gastroenterology

authors： Gilja OH,Detmer PR,Jong JM,Leotta DF,Li XN,Beach KW,Martin R,Strandness DE Jr

更新日期：1997-07-01 00:00:00

abstract：:The courses of 38 patients with severe, uncomplicated acute colitis (16 with Crohn's colitis and 22 with ulcerative colitis) were analyzed retrospectively. The patients were placed on total parenteral nutrition and treated concomitantly with corticosteroids, antibiotics (often metronidazole), sulfasalazine, and/or aza...

journal_title：Gastroenterology

authors： Sitzmann JV,Converse RL Jr,Bayless TM

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND & AIMS:Epithelial cells of the small intestine migrate to the tip of the villus at which they are shed. It is not understood how the intestinal barrier is maintained during this high cell turnover. The aim of this study was to use high-resolution in vivo light microscopy to investigate the mechanism of epith...

journal_title：Gastroenterology

authors： Watson AJ,Chu S,Sieck L,Gerasimenko O,Bullen T,Campbell F,McKenna M,Rose T,Montrose MH

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND & AIMS:Individuals with human immunodeficiency virus (HIV) infection frequently also are infected with hepatitis C virus (HCV) (co-infection), but little is known about its effects on the progression of HIV-associated disease. We aimed to determine the effects of co-infection on mortality from HIV and/or acq...

journal_title：Gastroenterology

authors： van der Helm J,Geskus R,Sabin C,Meyer L,Del Amo J,Chêne G,Dorrucci M,Muga R,Porter K,Prins M,CASCADE Collaboration in EuroCoord.

更新日期：2013-04-01 00:00:00