Abstract：
:Dopamine is synthesized from l-dopa and subsequently processed into norepinephrine and epinephrine. Any excess neurotransmitter can be taken up again by the neurons to be broken down enzymatically into DOPAC. The effect of dopamine on mammalian food intake is controversial. Mice unable to synthesize central dopamine die of starvation. However, studies have also shown that central injection of dopamine inhibits food intake. The effect of dopaminergic system in the fish feeding behavior has been scarcely explored. We report that the inclusion of l-dopa in the diets results in the activation of sea bass central dopaminergic system but also in the significant increase of the hypothalamic serotonin levels. Dietary l-dopa induces a decrease of food intake and feed conversion efficiency that drives a decline of all growth parameters tested. No behavioral effects were observed after l-dopa treatment. l-dopa treatment stimulated central expression of NPY and CRF. It suggests that CRF might mediate l-dopa effects on food intake but also that CRF neurons lie downstream of NPY neurons in the hierarchical forebrain system, thus controlling energy balance. Unexpectedly, dietary administration of haloperidol, a D2-receptor antagonist, cannot block dopamine effects but also induces a decline of the food intake. This decrease seems to be a side effect of haloperidol treatment since fish exhibited a decreased locomotor activity. We conclude that oral l-dopa inhibits sea bass food intake and growth. Mechanism could also involve an increase of hypothalamic serotoninergic tone.
journal_name
Horm Behavjournal_title
Hormones and behaviorauthors
Leal E,Fernández-Durán B,Agulleiro MJ,Conde-Siera M,Míguez JM,Cerdá-Reverter JMdoi
10.1016/j.yhbeh.2013.05.008subject
Has Abstractpub_date
2013-06-01 00:00:00pages
113-21issue
1eissn
0018-506Xissn
1095-6867pii
S0018-506X(13)00118-9journal_volume
64pub_type
杂志文章abstract：:The hormone oxytocin (OT) is released both centrally and peripherally during and after mating. Although research in humans suggests a central role in sexuality, the most reliable findings to date involve peripheral activation. This review will discuss these results and will particularly focus on understanding the most...
journal_title：Hormones and behavior
pub_type： 杂志文章,评审
doi：10.1016/j.yhbeh.2011.11.001
更新日期：2012-03-01 00:00:00
abstract：:We hypothesize that beneficial effects of estradiol on cognitive performance diminish with age and time following menopause due to a progressive decline in basal forebrain cholinergic function. This study tested whether galanthamine, a cholinesterase inhibitor used to treat memory impairment associated with Alzheimer'...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2011.08.010
更新日期：2011-11-01 00:00:00
abstract：:Children exhibit gender-typical preferences in play, toys, activities and interests, and playmates. Several studies suggest that high concentrations of pre- and postnatal androgens contribute to male-typical behavior development, whereas female-typical behavior develops in the absence of high androgens levels. This st...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2007.01.001
更新日期：2007-03-01 00:00:00
abstract：:Testosterone (T) appears to play a role in anxiety and sensorimotor gating in rodents, but whether T acts through the androgen receptor (AR) to influence these behaviors is less clear. We compared adult genetic male mice with the testicular feminization mutation (Tfm), which lack functional ARs, to wild type male litt...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2008.08.004
更新日期：2008-11-01 00:00:00
abstract：:As research neurobiologists, we pursue specific questions, and the answers rendered are also correspondingly specific. Our goal, however, is to understand an entire system or the whole organism. To that end, it is not only useful, but sometimes also necessary, that we periodically reappraise a body of specific data in...
journal_title：Hormones and behavior
pub_type： 杂志文章,评审
doi：10.1016/j.yhbeh.2007.08.007
更新日期：2008-01-01 00:00:00
abstract：:This article is part of a Special Issue "Energy Balance". Energy homeostasis is achieved through neuroendocrine and metabolic control of energy intake, storage, and expenditure. Traditionally, these controls have been studied in an unrealistic and narrow context. The appetite for food, for example, is most often assum...
journal_title：Hormones and behavior
pub_type： 社论
doi：10.1016/j.yhbeh.2014.05.001
更新日期：2014-06-01 00:00:00
abstract：:It has previously been shown that pre-pubertal or adult gonadectomy (GX) increases ethanol intake in male rats. This study examined whether this sex-selective increase reflects a GX-induced maintenance in males of more adolescent-typical responsiveness to ethanol characterized by enhanced sensitivity to positive (e.g....
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2014.04.015
更新日期：2014-07-01 00:00:00
abstract：:Fecal testosterone and cortisol levels were analyzed from six wild male muriquis (Brachyteles arachnoides) over a 19-month period at the Estação Biológica de Caratinga in Minas Gerais, Brazil, to investigate the hormonal correlates of seasonal sexual behavior and environmental conditions. Group mean testosterone level...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1006/hbeh.1998.1505
更新日期：1999-04-01 00:00:00
abstract：:In the field as well as in the laboratory, human-generated stress responses are reduced in adult animals previously habituated to humans in comparison to non-habituated individuals. In birds, yolk steroid levels vary with maternal environment and condition. We tested the hypothesis that the experience of female birds ...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2008.04.012
更新日期：2008-08-01 00:00:00
abstract：:Anthropogenic disturbance is a relevant and widespread facilitator of environmental change and there is clear evidence that it impacts natural populations. While population-level responses to major anthropogenic changes have been well studied, individual physiological responses to mild disturbance can be equally criti...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2010.08.001
更新日期：2010-11-01 00:00:00
abstract：:This article is part of a Special Issue "Chemosignals and Reproduction". Chemical cues were probably the first cues ever used to communicate and are still ubiquitous among living organisms. Birds have long been considered an exception: it was believed that birds were anosmic and relied on their acute visual and acoust...
journal_title：Hormones and behavior
pub_type： 杂志文章,评审
doi：10.1016/j.yhbeh.2014.06.001
更新日期：2015-02-01 00:00:00
abstract：:Imprinted genes, which are thought to comprise <1% of the mammalian genome, are defined by their parent-of-origin specific monoallelic expression arising as a consequence of differential epigenetic marking of alleles in the paternal and maternal germlines. Such genes are highly represented in the brain and placental t...
journal_title：Hormones and behavior
pub_type： 杂志文章,评审
doi：10.1016/j.yhbeh.2010.04.005
更新日期：2011-03-01 00:00:00
abstract：:Ovarian steroid hormones, estradiol and progesterone, regulate cellular functions in the central nervous system, resulting in the alterations in physiology and reproductive behavior. One means by which steroid hormones exert their neural effects on reproductive behavior is via their intracellular receptors functioning...
journal_title：Hormones and behavior
pub_type： 杂志文章,评审
doi：10.1006/hbeh.2001.1687
更新日期：2001-09-01 00:00:00
abstract：:While there exists increasing evidence of a relationship between testosterone (T) and risk-taking (RT), many issues remain unsolved. This paper tries to address two main-questions: (i) does T influence aggressive risk-taking (ART) and/or non-aggressive risk-taking (NART) behavior and (ii) is this relationship stable t...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2007.11.021
更新日期：2008-03-01 00:00:00
abstract：:Attention-deficit/hyperactivity disorder (ADHD) in adults is associated with significant impairment in many life activities and may thus increase the risk of chronic stress in everyday life. We compared adults with a DSM-IV ADHD diagnosis (n=28) with healthy controls (n=28) regarding subjective stress and amounts of s...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2008.12.004
更新日期：2009-03-01 00:00:00
abstract：:After proposing the organizational hypothesis from research in prenatally androgenized guinea pigs (Phoenix, C.H., Goy, R.W., Gerall, A.A., Young, W.C., 1959. Organizational action of prenatally administered testosterone propionate on the tissues mediating mating behavior in the female guinea pig. Endocrinology 65, 36...
journal_title：Hormones and behavior
pub_type： 杂志文章,评审
doi：10.1016/j.yhbeh.2009.03.015
更新日期：2009-05-01 00:00:00
abstract：:The effect of a high-fat diet on growth, sexual maturation, and developmental changes in serum levels of estradiol (E2), growth hormone (GH), somatomedin-C (Sm-C), and insulin were examined in outdoor-housed premenarchial rhesus monkeys. From 16 to 32 months of age, females were fed either a high-fat diet (HFD, N = 5)...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/0018-506x(88)90069-4
更新日期：1988-06-01 00:00:00
abstract：:Estrogen impairs performance on some striatum-sensitive tasks of learning and memory. Evidence indicates that it may have these impairing effects by creating a bias to use hippocampally based strategies to solve tasks whether or not it is advantageous to do so. Estrogen may also exert direct effects in the striatum to...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2005.05.001
更新日期：2006-01-01 00:00:00
abstract：:Three experiments were conducted to test whether testicular hormones secreted during puberty masculinize and defeminize the expression of adult reproductive behavior. Experiment 1 tested the hypothesis that gonadal hormones during puberty masculinize behavioral responses to testosterone (T) in adulthood. Male hamsters...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2003.12.007
更新日期：2004-04-01 00:00:00
abstract：:The individual time patterns of salivary testosterone of adult healthy men, self-reported sexual behavior and their co-occurrence with regular weekly or monthly intervals were studied. Twenty-seven volunteer males (mean age 33 +/- 1 years) collected daily morning saliva over a period of 90 days. Evening questionnaires...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1006/hbeh.2002.1815
更新日期：2002-09-01 00:00:00
abstract：:Coping strategies have been associated with differential stress responsivity, perhaps providing a valuable neurobiological marker for susceptibility to the emergence of depressogenic symptoms or vulnerability to other anxiety-related disorders. Rats profiled with a flexible coping phenotype, for example, exhibit incre...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2017.07.011
更新日期：2017-09-01 00:00:00
abstract：:Androgens are often associated with assertive behavior; under what circumstances is this reflected in higher dominance rank? In this study of coresidential college women, androgens (total testosterone, free testosterone, and androstenedione) and estradiol were positively correlated with high self-regard in women (as m...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1006/hbeh.1995.1025
更新日期：1995-09-01 00:00:00
abstract：:Corticotropin-releasing factor (CRF) plays a critical role in the mediation of physiological and behavioral responses to stressors. In the present study, we investigated the role played by the CRF system within the medial amygdala (MeA) in the modulation of anxiety and fear-related responses. Male Wistar rats were bil...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2014.01.004
更新日期：2014-03-01 00:00:00
abstract：:Previous studies have provided evidence that humans demonstrate subtle, but measurable, turning biases when tested in the absence of environmental constraints. Preferences for leftward or rightward rotation have been repeatedly demonstrated in rodents and appear to be modulated to a significant degree by ovarian hormo...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1006/hbeh.1997.1363
更新日期：1997-02-01 00:00:00
abstract：:The psychoendocrinology of the development of normal gender identity and its variations is poorly understood. Studies of gender development in individuals born with endocrinologically well-characterized intersex conditions are heuristically valuable for the disaggregation of factors that are acting in concert during n...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1006/hbeh.1996.0039
更新日期：1996-12-01 00:00:00
abstract：:Depression is one of the most common mental disorders and a primary cause of disability. To better treat patients suffering this illness, elucidation of the underlying psychopathological and neurobiological mechanisms is urgently needed. Based on the above-mentioned evidence, we sought to investigate the effects of ne...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2015.05.018
更新日期：2015-07-01 00:00:00
abstract：:Patients with thyroid dysfunction (31 hypothyroid, 32 subclinical hypothyroidism, 34 hyperthyroid, and 30 subclinical hyperthyroidism) and 37 euthyroid control subjects were recruited and performed the attention network test (ANT), which can simultaneously examine the alertness, orientation and execution control of th...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2020.104714
更新日期：2020-05-01 00:00:00
abstract：:Motivated social behaviors such as mating are controlled by a complex network of limbic nuclei. Concepts of network organization derived from computational neuroscience may aid our understanding of the links between the neuroanatomical circuitry and what is represented by the anatomy. Research in my laboratory uses ma...
journal_title：Hormones and behavior
pub_type： 杂志文章,评审
doi：10.1006/hbeh.1997.1403
更新日期：1997-08-01 00:00:00
abstract：:Previous research in the zebra finch, a socially monogamous pair-bonding species, suggests that the preference for opposite-sex partners may arise in part through the organizing actions of sex steroids. To further investigate this process, zebra finch eggs were injected with 20 microg fadrozole, a potent estrogen synt...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1006/hbeh.2000.1627
更新日期：2001-02-01 00:00:00
abstract：:Many studies have attempted to identify biological factors that reliably predict individual differences in women's preferences for masculine male faces. Marcinkowska et al. (2018, Hormones & Behavior) recently reported that women's (N = 102) preferences for facial masculinity were predicted by the interaction between ...
journal_title：Hormones and behavior
pub_type： 杂志文章
doi：10.1016/j.yhbeh.2018.12.004
更新日期：2019-01-01 00:00:00
